We narrowed to 29,405 results for: des.2

1. pcDNA3.1 NKX6-2(1-40)-Venus

   Plasmid

   #203713

   Purpose

   SPAX8-related truncated mutation (K41*) containing the amino acids 1 to 40 of human NKX6-2, fused with the Venus fluorescent protein.

   Depositor

   Federico Herrera

   Article

   Ferreira-Peralta et al Biochim Biophys Acta Mol Basis Dis. 2023

   Insert

   NKX6-2 (1-40) fused with Venus (NKX6-2 Human)
   

   Tags

   Venus

   Expression

   Mammalian

   Mutation

   deletion of amino acids 41-277

   Promoter

   CMV

   Available Since

   Sept. 22, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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2. pLKO.1-Teton-puro-shPP1C #2

   Plasmid

   #198763

   Purpose

   conditional knockdown of PP1C

   Depositor

   Hyonchol Jang

   Article

   Kim et al Cancers (Basel). 2020 Sep 11;12(9):2601.

   Insert

   shPP1C #2 (PPP1CC Human)
   

   Expression

   Mammalian

   Available Since

   April 21, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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3. pGEX-GP-2-KDM4A double Tudor

   Plasmid

   #59699

   Purpose

   Contains histone modification interacting domain (KDM4A double Tudor)

   Depositor

   Albert Jeltsch

   Article

   Kungulovski et al Genome Res. 2014 Nov;24(11):1842-53. doi

   Insert

   KDM4A double Tudor (KDM4A Human)
   

   Tags

   GST

   Expression

   Bacterial

   Promoter

   tac promoter

   Available Since

   Oct. 17, 2014

   Availability

   Academic Institutions and Nonprofits only

   

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4. HH02-LP Clone 2 heavy chain

   Plasmid

   #192175

   Purpose

   Clone 2 heavy chain (HH02)

   Depositor

   Sidi Chen

   Article

   Peng et al Nat Commun. 2022 Mar 28;13(1):1638. doi:

   Insert

   Clone 2 heavy chain (HH02)
   

   Expression

   Mammalian

   Mutation

   NA

   Available Since

   Dec. 8, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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5. HK02-LP Clone 2 light chain

   Plasmid

   #192179

   Purpose

   Clone 2 light chain (HK02)

   Depositor

   Sidi Chen

   Article

   Peng et al Nat Commun. 2022 Mar 28;13(1):1638. doi:

   Insert

   Clone 2 light chain (HK02)
   

   Expression

   Mammalian

   Mutation

   NA

   Available Since

   Oct. 27, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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6. pCAGGS SARS-CoV-2 XBB Spike

   Plasmid

   #195287

   Purpose

   Expresses codon-optimized full length SARS-CoV-2 XBB Spike

   Depositor

   Marceline Côté

   Insert

   SARS-CoV-2 XBB Spike (S )
   

   Expression

   Mammalian

   Mutation

   Contains the following mutations: T19I, LPPA24-27…

   Promoter

   chicken β-actin promoter, CMV enhancer

   Available Since

   Feb. 8, 2023

   Availability

   Industry, Academic Institutions, and Nonprofits

   

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7. pEGFP C3-Lats1-PY1+2 mutant

   Plasmid

   #19054

   Depositor

   Marius Sudol

   Article

   Oka et al J Biol Chem. 2008 Oct 10;283(41):27534-2

   Insert

   Large tumor suppressor kinase 1, N mutant (LATS1 Human)
   

   Tags

   EGFP

   Expression

   Mammalian

   Mutation

   PY1 mutant, (Tyrosine 376 changed to Alanine) and…

   Available Since

   Sept. 8, 2008

   Availability

   Academic Institutions and Nonprofits only

8. TET-pLKO.1 PURO shId2 #2

   Plasmid

   #83090

   Purpose

   Lentiviral shRNA vector for inducible knockdown of mouse Id2

   Depositor

   Kevin Janes

   Article

   Bajikar et al Dev Cell. 2017 Nov 20;43(4):418-435.e13.

   Insert

   shId2 (Id2 Mouse)
   

   Use

   Lentiviral

   Expression

   Mammalian

   Available Since

   Feb. 28, 2019

   Availability

   Academic Institutions and Nonprofits only

9. pLKO human shRNA 2 c-MAF

   Plasmid

   #29433

   Depositor

   David Sabatini

   Article

   Peterson et al Cell. 2009 May 29;137(5):873-86. doi: 10

   Insert

   c-MAF shRNA 2 (MAF Human)
   

   Use

   Lentiviral and RNAi

   Expression

   Mammalian

   Available Since

   April 7, 2011

   Availability

   Academic Institutions and Nonprofits only

10. pPICZ A-SLC25A46[∆2-83]-His (SB258)

    Plasmid

    #227607

    Purpose

    Inducible expression of His-tagged SLC25A46 lacking its N-terminal region (∆2-83) in Pichia pastoris

    Depositor

    Luke Chao

    Article

    Boopathy et al J Biol Chem. 2024 Aug 31:107740. doi: 10

    Insert

    SLC25A46 (SLC25A46 Human)
    

    Tags

    10xHis

    Expression

    Yeast

    Mutation

    aa 2-83 deleted

    Promoter

    AOX1

    Available Since

    Dec. 6, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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11. GFP-Bcl-2-G128L-A131L-T132L

    Plasmid

    #220304

    Purpose

    mammalian expression of Bcl-2-G128L-A131L-T132L tagged with GFP

    Depositor

    Xinlai Cheng

    Article

    Wang et al Cell Reports Physical Science, Volume 5,

    Insert

    Bcl2 (BCL2 Human)
    

    Tags

    Emerald GFP

    Expression

    Mammalian

    Mutation

    G128L-A131L-T132L

    Promoter

    CMV

    Available Since

    June 17, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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12. pKLV2-U6gRNA5(Control(2))-PGKpuro2AmCherry-W

    Plasmid

    #210613

    Purpose

    Lentiviral vector expressing gRNA targeting a control region at the CXCR4 locus

    Depositor

    Kosuke Yusa

    Article

    Aoki et al Blood. 2023 Nov 3:blood.2023020857. doi:

    Insert

    Control(2)
    

    Use

    Lentiviral

    Available Since

    Jan. 8, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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13. pSpCas9(BB)-2A-mCherry_MAPRE3-gRNA#2

    Plasmid

    #197422

    Purpose

    Knock out of EB3 in human cells by CRISPR/Cas9

    Depositor

    Torsten Wittmann

    Article

    Dema et al Elife. 2023 Jan 30;12:e84143. doi: 10.75

    Insert

    MAPRE3 gRNA #2 (targets Exon 1) (MAPRE3 Human)
    

    Use

    CRISPR

    Available Since

    June 26, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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14. RPS15A sgRNA-2 lentiCRISPR v2 plasmid

    Plasmid

    #192228

    Purpose

    lentiviral vector expressing sgRNA-2 targeting eIF3 binding site of RPS15A 5'UTR

    Depositor

    Dieter Wolf

    Article

    Duan et al EMBO J. 2023 Jun 15;42(12):e112362. doi:

    Insert

    sgRNA-2 targeting eIF3 binding site of RPS15A 5'UTR (RPS15A Human)
    

    Use

    CRISPR and Lentiviral

    Available Since

    Dec. 19, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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15. BMP10 N67Q N131Q D4G (S2-2)

    Plasmid

    #184622

    Purpose

    for transfection into S2 cells and expression of BMP10 protein

    Depositor

    Timothy Springer

    Article

    Le et al J Mol Biol. 2022 Mar 15;434(5):167439. d

    Insert

    BMP10 (BMP10 Human)
    

    Tags

    8x His - streptavidin binding peptide

    Expression

    Insect

    Mutation

    N67Q, N131Q, ARIRR(312-316) replaced with G

    Available Since

    June 29, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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16. TET-pLKO.1 PURO shGDF11 #2

    Plasmid

    #83084

    Purpose

    Lentiviral shRNA vector for inducible knockdown of human GDF11

    Depositor

    Kevin Janes

    Article

    Bajikar et al Dev Cell. 2017 Nov 20;43(4):418-435.e13.

    Insert

    shGDF11 (GDF11 Human)
    

    Use

    Lentiviral

    Expression

    Mammalian

    Available Since

    Feb. 28, 2019

    Availability

    Academic Institutions and Nonprofits only

17. LSB-hsa-miR-181b-2-3p

    Plasmid

    #103277

    Purpose

    Used to sense miRNA activity using fluorescence based tools. hsa-miR-181b-2-3p target in 3' UTR of of mKate. miRNA activity can be measured by the repression of mKate2 relative to EBFP2 fluorescent proteins . Plasmid is inherently unstable; please see Depositor Comments

    Depositor

    Ron Weiss

    Article

    Gam et al Nat Commun. 2018 Jun 22;9(1):2430. doi:

    Insert

    hsa-miR-181b-2-3p target
    

    Use

    Synthetic Biology

    Expression

    Mammalian

    Promoter

    EF-1a

    Available Since

    Nov. 26, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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18. LSB-hsa-miR-125b-2-3p

    Plasmid

    #103190

    Purpose

    Used to sense miRNA activity using fluorescence based tools. hsa-miR-125b-2-3p target in 3' UTR of of mKate. miRNA activity can be measured by the repression of mKate2 relative to EBFP2 fluorescent proteins . Plasmid is inherently unstable; please see Depositor Comments

    Depositor

    Ron Weiss

    Article

    Gam et al Nat Commun. 2018 Jun 22;9(1):2430. doi:

    Insert

    hsa-miR-125b-2-3p target
    

    Use

    Synthetic Biology

    Expression

    Mammalian

    Promoter

    EF-1a

    Available Since

    Nov. 26, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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19. TRS6E1b-luc(-732/-721) mutant 2

    Plasmid

    #45385

    Depositor

    Thomas Gelehrter

    Article

    Song et al J Biol Chem. 1998 Nov 6;273(45):29287-90

    Insert

    6 copies of hPAI-1 promoter -732/-721 mutated at -730/-728
    

    Use

    Luciferase

    Tags

    luciferase

    Expression

    Mammalian

    Mutation

    mutated at -730/-728 from aca to tgt

    Available Since

    June 20, 2013

    Availability

    Academic Institutions and Nonprofits only

20. pPGK-T7/2-CD44v8-10 (fl)

    Plasmid

    #137823

    Purpose

    expression of CD44 proteins in mammalian cells

    Depositor

    Ursula Gunthert

    Article

    Mielgo et al Cell Death Differ. 2006 Mar;13(3):465-77

    Insert

    CD44v8-10 (fl) (CD44 Human)
    

    Tags

    GFP

    Expression

    Mammalian

    Mutation

    full length

    Promoter

    PGK

    Available Since

    Aug. 6, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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