375 results

1. FNLCR CRISPRa Cell Surface and FNLCR CRISPRa Soluble Libraries

   Pooled Library

   #1000000228

   Depositor

   Raj Chari

   Available since

   Jan. 24, 2024

   Availability

   Academic Institutions and Nonprofits only

2. Human CRISPRa sgRNA library Calabrese in backbone XPR_502 (P65 HSF)

   Pooled Library

   #1000000111

   Purpose

   Genome-wide CRISPR gRNA pooled library for activation of human genes

   Depositor

   David Root, John Doench

   Available since

   Aug. 3, 2017

   Availability

   Academic Institutions and Nonprofits only

3. Human sgRNA library Brunello in lentiCRISPRv2

   Pooled Library

   #73179

   Purpose

   Human sgRNA library in backbone lentiCRISPRv2 targeting 19,114 genes and containing 76,441 unique sgRNAs along with 1000 non-targeting controls

   Depositor

   David Root, John Doench

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Has Service

   Lentiviral Prep

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available since

   Feb. 9, 2016

   Availability

   Academic Institutions and Nonprofits only

4. Human CRISPR Metabolic Gene Knockout Library

   Pooled Library

   #110066

   Purpose

   Encodes gRNAs for targeting metabolic genes in CRISPR screens.

   Depositor

   David Sabatini

   Article

   Birsoy et al Cell. 2015 Jul 30;162(3):540-51. doi: 10

   Use

   Lentiviral

   Available since

   May 4, 2018

   Availability

   Academic Institutions and Nonprofits only

5. Human sgRNA library Brunello in lentiGuide-Puro

   Pooled Library

   #73178

   Purpose

   Human sgRNA library in backbone lentiGuide-Puro targeting 19,114 genes and containing 76,441 unique sgRNAs along with 1000 non-targeting controls

   Depositor

   David Root, John Doench

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Has Service

   Lentiviral Prep

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available since

   Feb. 9, 2016

   Availability

   Academic Institutions and Nonprofits only

6. MORF Library Kit with GFP and mCherry controls

   Pooled Library

   #1000000218

   Depositor

   Feng Zhang

   Available since

   March 24, 2023

   Availability

   Academic Institutions and Nonprofits only

7. MinLibCas9

   Pooled Library

   #164896

   Purpose

   Human genome-wide CRISPR-Cas9 gRNA library, optimised by mining existing large-scale screening datasets, which provides a >60% reduction in size while preserving key information content

   Depositor

   Mathew Garnett

   Article

   Gonçalves et al Genome Biol. 2021 Jan 21;22(1):40. doi:

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   May 20, 2021

   Availability

   Academic Institutions and Nonprofits only

8. ClonTracer Barcoding Library (2.5 ug)

   Pooled Library

   #67267

   Purpose

   High complexity 30bp-long semi random DNA barcode library in lentiviral backbone

   Depositor

   Frank Stegmeier

   Article

   Bhang et al Nat Med. 2015 Apr 13. doi: 10.1038/nm.38

   Expression

   Mammalian

   Species

   Synthetic

   Use

   Lentiviral

   Available since

   Sept. 11, 2015

   Availability

   Academic Institutions and Nonprofits only

9. Toronto KnockOut version 3 library (TKOv3)

   Pooled Library

   #90294

   Purpose

   Optimized library offering improved accuracy, efficiency, and scalability for CRISPR screens compared to TKOv1

   Depositor

   Jason Moffat

   Article

   Hart et al G3 (Bethesda). 2017 Aug 7;7(8):2719-2727

   Available since

   May 5, 2017

   Availability

   Academic Institutions and Nonprofits only

10. Human Epigenetic Knockout Library

    Pooled Library

    #162256

    Purpose

    Lentiviral CRISPR library targets human epigenetic genes

    Depositor

    Kivanc Birsoy

    Article

    Williams et al Cell Metab. 2020 Apr 7;31(4):852-861.e6.

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    Nov. 17, 2020

    Availability

    Academic Institutions and Nonprofits only

11. lentiCRISPRv2_ISG

    Pooled Library

    #125753

    Purpose

    Expresses gRNAs targeting human Interferon-Stimulated Genes

    Depositor

    Molly OhAinle, Michael Emerman

    Article

    Roesch et al Retrovirology. 2018 Mar 20;15(1):26. doi

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    May 7, 2020

    Availability

    Academic Institutions and Nonprofits only

12. hCRISPRa-v2, Membrane Proteins (h6), top 5 sgRNAs/gene

    Pooled Library

    #83985

    Purpose

    Human CRISPRa Pooled Library targeting membrane proteins

    Depositor

    Jonathan Weissman

    Article

    Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

    Available since

    Jan. 12, 2017

    Availability

    Academic Institutions and Nonprofits only

13. Human genome-wide lentiviral CRISPR gRNA library version 1

    Pooled Library

    #67989

    Purpose

    Human genome-wide CRISPR guide RNA library V1 (pKLV2-U6gRNA5(HumanV1)-PGKpuro2ABFP-W)

    Depositor

    Kosuke Yusa

    Article

    Tzelepis et al Cell Rep. 2016 Oct 18;17(4):1193-1205. d

    Species

    Homo sapiens, Mus musculus, and Synthetic

    Use

    CRISPR and Lentiviral

    Available since

    Oct. 14, 2016

    Availability

    Academic Institutions and Nonprofits only

14. Mouse genome-wide lentiviral CRISPR gRNA library version 2

    Pooled Library

    #67988

    Purpose

    Mouse genome-wide CRISPR guide RNA library V2. (pKLV2-U6gRNA5(MouseV2)-PGKpuro2ABFP-W)

    Depositor

    Kosuke Yusa

    Article

    Tzelepis et al Cell Rep. 2016 Oct 18;17(4):1193-1205. d

    Species

    Homo sapiens, Mus musculus, and Synthetic

    Use

    CRISPR and Lentiviral

    Available since

    Oct. 14, 2016

    Availability

    Academic Institutions and Nonprofits only

15. Lenti-human-TF-gRNA-puromycin

    Pooled Library

    #162275

    Purpose

    This is a gRNA library targeting on ~1600 human transcription factors for genetic screening.

    Depositor

    Chunliang Li

    Article

    Zhang et al Elife. 2020 Oct 1;9. pii: 57858. doi: 10

    Species

    Homo sapiens

    Use

    Lentiviral

    Available since

    Dec. 15, 2020

    Availability

    Academic Institutions and Nonprofits only

16. Human Kinase Domain-Focused CRISPR Knockout Library

    Pooled Library

    #117725

    Purpose

    gRNAs targeting the kinase domain of human protein kinases

    Depositor

    Christopher Vakoc

    Article

    Tarumoto et al Mol Cell. 2018 Feb 28. pii: S1097-2765(1

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    Jan. 4, 2019

    Availability

    Academic Institutions and Nonprofits only

17. Mouse Brie kinome pooled library, guides 1-4 in lentiGuide-Puro backbone

    Pooled Library

    #75316

    Purpose

    Mouse sgRNA library in backbone lentiGuide-Puro targeting 713 kinase genes and containing 2,852 unique sgRNAs along with 100 non-targeting controls

    Depositor

    David Root, John Doench

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Available since

    June 27, 2016

    Availability

    Academic Institutions and Nonprofits only

18. MORF library without GFP and mCherry controls

    Pooled Library

    #192821

    Purpose

    Barcoded transcription factor ORF library for high throughput screening

    Depositor

    Feng Zhang

    Article

    Joung et al Cell. 2023 Jan 5;186(1):209-229.e26. doi

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    Lentiviral

    Available since

    Jan. 11, 2023

    Availability

    Academic Institutions and Nonprofits only

19. pSMAL-CellTag-V2

    Pooled Library

    #115644

    Purpose

    Viral barcoding library to combinatorially index cells for single-cell analysis of clonal dynamics

    Depositor

    Samantha Morris

    Article

    Biddy et al Nature. 2018 Dec;564(7735):219-224. doi:

    Has Service

    Concentrated Lentiviral Prep

    Expression

    Mammalian

    Species

    Synthetic

    Use

    Lentiviral

    Available since

    Dec. 5, 2018

    Availability

    Academic Institutions and Nonprofits only

20. pSMAL-CellTag-V3

    Pooled Library

    #115645

    Purpose

    Viral barcoding library to combinatorially index cells for single-cell analysis of clonal dynamics

    Depositor

    Samantha Morris

    Article

    Biddy et al Nature. 2018 Dec;564(7735):219-224. doi:

    Has Service

    Concentrated Lentiviral Prep

    Expression

    Mammalian

    Species

    Synthetic

    Use

    Lentiviral

    Available since

    Dec. 5, 2018

    Availability

    Academic Institutions and Nonprofits only