378 results

1. Mouse Toronto KnockOut (mTKO) CRISPR Library - lentiCRISPRv2

   Pooled Library

   #159392

   Purpose

   Mouse lentiviral genome-wide CRISPR library

   Depositor

   Jason Moffat

   Article

   Lawson et al Nature. 2020 Oct;586(7827):120-126. doi:

   Expression

   Mammalian

   Species

   Mus musculus

   Use

   CRISPR and Lentiviral

   Available since

   Nov. 9, 2020

   Availability

   Academic Institutions and Nonprofits only

2. Human sgRNA library Brunello in lentiGuide-Puro

   Pooled Library

   #73178

   Purpose

   Human sgRNA library in backbone lentiGuide-Puro targeting 19,114 genes and containing 76,441 unique sgRNAs along with 1000 non-targeting controls

   Depositor

   David Root, John Doench

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Has Service

   Lentiviral Prep

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available since

   Feb. 9, 2016

   Availability

   Academic Institutions and Nonprofits only

3. Mouse Chromatin Regulator Library

   Pooled Library

   #200011

   Purpose

   CRISPR KO library targeting a comprehensive set of genes with annotated function as chromatin regulators.

   Depositor

   Bradley Bernstein, Gabriel Griffin, Robert Manguso

   Article

   Griffin et al Nature. 2021 Jul;595(7866):309-314. doi:

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available since

   Dec. 15, 2023

   Availability

   Academic Institutions and Nonprofits only

4. Murine cell surface protein knockout (McspKO) library

   Pooled Library

   #200445

   Purpose

   A CRISPR library targeting 1,157 cell surface genes and 98 control genes with four sgRNAs per gene

   Depositor

   Junjie Chen

   Article

   Wang et al Proc Natl Acad Sci U S A. 2022 Jun 21;11

   Expression

   Mammalian

   Species

   Mus musculus

   Use

   CRISPR, Lentiviral, and Mouse Targeting

   Available since

   Oct. 26, 2023

   Availability

   Academic Institutions and Nonprofits only

5. hCRISPRi-v2, genome-wide, top 5 sgRNAs/gene

   Pooled Library

   #83969

   Purpose

   Version 2 of the human CRISPRi genome wide library

   Depositor

   Jonathan Weissman

   Article

   Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

   Use

   Lentiviral

   Available since

   Nov. 15, 2016

   Availability

   Academic Institutions and Nonprofits only

6. MinLibCas9

   Pooled Library

   #164896

   Purpose

   Human genome-wide CRISPR-Cas9 gRNA library, optimised by mining existing large-scale screening datasets, which provides a >60% reduction in size while preserving key information content

   Depositor

   Mathew Garnett

   Article

   Gonçalves et al Genome Biol. 2021 Jan 21;22(1):40. doi:

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   May 20, 2021

   Availability

   Academic Institutions and Nonprofits only

7. Human SAM library in lenti sgRNA(MS2)_puro backbone

   Pooled Library

   #1000000074

   Purpose

   Genome-wide CRISPR gRNA pooled library for activation of mouse genes

   Depositor

   Feng Zhang

   Available since

   March 17, 2016

   Availability

   Academic Institutions and Nonprofits only

8. hCRISPRi-v2, Membrane Proteins (h6), top 5 sgRNAs/gene

   Pooled Library

   #83976

   Purpose

   Human CRISPRi Pooled Library targeting membrane proteins

   Depositor

   Jonathan Weissman

   Article

   Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

   Available since

   Dec. 14, 2016

   Availability

   Academic Institutions and Nonprofits only

9. Mouse sgRNA library Brie in lentiGuide-Puro

   Pooled Library

   #73633

   Purpose

   Mouse sgRNA library in backbone lentiGuide-Puro containing 78,637 unique sgRNAs targeting 19,674 genes along with 1000 non-targeting controls

   Depositor

   David Root, John Doench

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Has Service

   Lentiviral Prep

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available since

   Feb. 25, 2016

   Availability

   Academic Institutions and Nonprofits only

10. Human GeCKO Lentiviral sgRNA Library v2 (lentiGuide-Puro)

    Pooled Library

    #1000000049

    Purpose

    CRISPR gRNA knockout pooled library for targeting the human genome

    Depositor

    Feng Zhang

    Available since

    May 8, 2014

    Availability

    Academic Institutions and Nonprofits only

11. Glycogene CRISPR Library

    Pooled Library

    #140961

    Purpose

    Targets human genes involved in cellular glycosylation.

    Depositor

    Sriram Neelamegham

    Article

    Zhu et al Glycobiology. 2020 Aug 8. pii: 5889976.

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    Sept. 9, 2020

    Availability

    Academic Institutions and Nonprofits only

12. Human sgRNA library Brunello in lentiCRISPRv2

    Pooled Library

    #73179

    Purpose

    Human sgRNA library in backbone lentiCRISPRv2 targeting 19,114 genes and containing 76,441 unique sgRNAs along with 1000 non-targeting controls

    Depositor

    David Root, John Doench

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Has Service

    Lentiviral Prep

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available since

    Feb. 9, 2016

    Availability

    Academic Institutions and Nonprofits only

13. Human GeCKO Lentiviral sgRNA Library v2 (LentiCRISPR)

    Pooled Library

    #1000000048

    Purpose

    CRISPR gRNA knockout pooled library for targeting the human genome

    Depositor

    Feng Zhang

    Available since

    May 8, 2014

    Availability

    Academic Institutions and Nonprofits only

14. Mouse sgRNA library Brie in lentiCRISPRv2

    Pooled Library

    #73632

    Purpose

    Mouse sgRNA library in backbone lentiCRISPRv2 containing 78,637 unique sgRNAs targeting 19,674 genes along with 1000 non-targeting controls

    Depositor

    David Root, John Doench

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available since

    Feb. 25, 2016

    Availability

    Academic Institutions and Nonprofits only

15. STICR_IndexE

    Pooled Library

    #180483

    Purpose

    High Complexity Lentiviral Barcode Library

    Depositor

    Tomasz Nowakowski

    Article

    Delgado et al Nature. 2021 Dec 15. pii: 10.1038/s41586

    Expression

    Mammalian

    Species

    Synthetic

    Use

    Lentiviral

    Available since

    Sept. 12, 2022

    Availability

    Academic Institutions and Nonprofits only

16. Human Metabolic Gene CRISPRa sgRNA library

    Pooled Library

    #187080

    Purpose

    Lentiviral CRISPRa library targeting human metabolic genes for activation of gene expression

    Depositor

    Kivanc Birsoy

    Article

    Unlu et al Mol Cell. 2022 Aug 4;82(15):2832-2843.e7

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    Lentiviral

    Available since

    Oct. 26, 2022

    Availability

    Academic Institutions and Nonprofits only

17. Bassik lab Human CRISPR-Cas9 Deletion Library - Membrane proteins

    Pooled Library

    #101929

    Purpose

    Bassik lab Human CRISPR-Cas9 Deletion Library - Membrane proteins. Coexpresses mCherry.

    Depositor

    Michael Bassik

    Article

    Morgens et al Nat Commun. 2017 May 5;8:15178. doi: 10.

    Expression

    Mammalian

    Use

    CRISPR

    Available since

    May 23, 2018

    Availability

    Academic Institutions and Nonprofits only

18. MORF Library Kit with GFP and mCherry controls

    Pooled Library

    #1000000218

    Depositor

    Feng Zhang

    Available since

    March 24, 2023

    Availability

    Academic Institutions and Nonprofits only

19. RNA-binding protein pooled CRISPR knockout library

    Pooled Library

    #141438

    Purpose

    CRISPR knockout library targets RBPs with 10 sgRNAs/gene

    Depositor

    Eugene Yeo

    Article

    Wheeler et al Nat Methods. 2020 May 11. pii: 10.1038/s

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available since

    May 28, 2020

    Availability

    Academic Institutions and Nonprofits only

20. pSMAL-CellTag-V1

    Pooled Library

    #115643

    Purpose

    Viral barcoding library to combinatorially index cells for single-cell analysis of clonal dynamics

    Depositor

    Samantha Morris

    Article

    Biddy et al Nature. 2018 Dec;564(7735):219-224. doi:

    Has Service

    Concentrated Lentiviral Prep

    Expression

    Mammalian

    Species

    Synthetic

    Use

    Lentiviral

    Available since

    Dec. 5, 2018

    Availability

    Academic Institutions and Nonprofits only