We narrowed to 124 results for: {{{s}}}

1. Mouse sphingolipid metabolism knockout library

   Pooled Library

   #206249

   Purpose

   The sphingolipid metabolism library targets 82 mouse genes in the de novo ceramide and downstream sphingolipid metabolism pathways.

   Depositor

   Kivanc Birsoy

   Article

   Soula et al Nature. 2024 Aug 7. doi: 10.1038/s41586-

   Use

   CRISPR and Lentiviral

   Available Since

   Aug. 29, 2024

   Availability

   Academic Institutions and Nonprofits only

2. Mouse lipid metabolism knockout library

   Pooled Library

   #206248

   Purpose

   The lipid metabolism library contains guide RNAs against 295 genes targeting mouse genes encoding enzymes that directly impact lipid metabolism.

   Depositor

   Kivanc Birsoy

   Article

   Soula et al Nature. 2024 Aug 7. doi: 10.1038/s41586-

   Use

   CRISPR and Lentiviral

   Available Since

   Aug. 29, 2024

   Availability

   Academic Institutions and Nonprofits only

3. pC004 - PFS library in Beta-lactamase gene Target Plasmid

   Pooled Library

   #79153

   Purpose

   Library of protospacer flanking sites (PFS) inserted at the 5' end of the β-lactamase gene for screening PFS preference for Cas13a/C2c2.

   Depositor

   Feng Zhang

   Article

   Abudayyeh et al Science. 2016 Jun 2. pii: aaf5573.

   Available Since

   Oct. 26, 2017

   Availability

   Academic Institutions and Nonprofits only

4. CRASP-Seq CBC Backbone

   Pooled Library

   #232068

   Purpose

   The CRASP-Seq backbone is designed to accommodate the cloning of diverse gRNA libraries. It includes a cell barcode (CBC), which enhances its functionality by enabling library preparation.

   Depositor

   Thomas Gonatopoulos-Pournatzis

   Article

   Behera et al bioRxiv [Preprint]. 2025 Apr 26:2025.04.

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available Since

   Oct. 28, 2025

   Availability

   Academic Institutions and Nonprofits only

5. CRASP-Seq Gene KO v1 empty

   Pooled Library

   #232069

   Purpose

   Knockout library for use in CRASP-Seq experiments. Provides a flexible platform for studying splicing regulation.

   Depositor

   Thomas Gonatopoulos-Pournatzis

   Article

   Behera et al bioRxiv [Preprint]. 2025 Apr 26:2025.04.

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available Since

   Oct. 28, 2025

   Availability

   Academic Institutions and Nonprofits only

6. CRASP-Seq BE Tiling v1 empty

   Pooled Library

   #232070

   Purpose

   Tiling library to conduct CRASP-Seq experiments combined with high-throughput base editing for precise and scalable investigations into protein regions that affect splicing regulation.

   Depositor

   Thomas Gonatopoulos-Pournatzis

   Article

   Behera et al bioRxiv [Preprint]. 2025 Apr 26:2025.04.

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available Since

   Oct. 28, 2025

   Availability

   Academic Institutions and Nonprofits only

7. BLaER1 pgRNA CRISPR library

   Pooled Library

   #183825

   Purpose

   Paired gRNA library targeting genes related to B-cell to macrophage transdifferentiation.

   Depositor

   Roderic Guigo

   Article

   Arnan et al BMC Genomics. 2022 May 26;23(1):402. doi

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available Since

   Aug. 25, 2022

   Availability

   Academic Institutions and Nonprofits only

8. Yeast Inducible CRISPRi Library

   Pooled Library

   #161829

   Purpose

   Inducible genome-wide CRISPRi library targeting S. cerevisiae genes with 6-12 guide RNAs per gene.

   Depositor

   Saeed Tavazoie

   Article

   Momen-Roknabadi et al Commun Biol. 2020 Nov 27;3(1):723. doi:

   Expression

   Yeast

   Species

   Saccharomyces cerevisiae

   Use

   CRISPR

   Available Since

   April 28, 2021

   Availability

   Academic Institutions and Nonprofits only

9. ACER

   Pooled Library

   #226117

   Purpose

   Contains 748 traditional and newly predicted epigenetic regulators using epigenetic network analyses that integrated gene codependency (DepMap) and protein-protein interaction data (BioPlex).

   Depositor

   Rui Lu

   Article

   Zhou et al Blood. 2024 Aug 16:blood.2023023644. doi

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available Since

   Oct. 29, 2024

   Availability

   Academic Institutions and Nonprofits only

10. mTF-CRISPRai

    Pooled Library

    #122131

    Purpose

    Increases transcriptional repression of genes encoding transcription factors in combination with dCas9 repression systems, such as the dCas9-KRAB system.

    Depositor

    Stanley Qi

    Article

    Liu et al Cell Stem Cell. 2018 Sep 28. pii: S1934-

    Expression

    Mammalian

    Species

    Mus musculus

    Use

    CRISPR and Lentiviral

    Available Since

    April 25, 2019

    Availability

    Academic Institutions and Nonprofits only

11. Ma-PylRS-lib1

    Pooled Library

    #224585

    Purpose

    Pyrrolysine tRNA synthetase library to generate new genetic code expansion (GCE) systems for site-specific incorporation of non-canonical amino acids (ncAAs) into proteins.

    Depositor

    Ryan Mehl

    Article

    Avila-Crump et al ACS Chem Biol. 2022 Dec 16;17(12):3458-3

    Expression

    Bacterial

    Species

    Methanomethylophilus alvus

    Available Since

    Jan. 6, 2025

    Availability

    Academic Institutions and Nonprofits only

12. Lenti-human-UBDUB-gRNA-puromycin-IRES-CFP

    Pooled Library

    #171531

    Purpose

    Knockout library targeting ubiquitination and de-ubiquitination complex genes.

    Depositor

    Chunliang Li

    Article

    Wright et al Proc Natl Acad Sci U S A. 2023 Apr 18;12

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    Lentiviral

    Available Since

    June 22, 2021

    Availability

    Academic Institutions and Nonprofits only

13. Human Epigenetic Knockout Library

    Pooled Library

    #162256

    Purpose

    Knockout library that targets human epigenetic genes.

    Depositor

    Kivanc Birsoy

    Article

    Williams et al Cell Metab. 2020 Apr 7;31(4):852-861.e6.

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available Since

    Nov. 17, 2020

    Availability

    Academic Institutions and Nonprofits only

14. Mouse Chromatin Regulator Library

    Pooled Library

    #200011

    Purpose

    Knockout library targeting a comprehensive set of mouse genes with annotated function as chromatin regulators.

    Depositor

    Bradley Bernstein, Gabriel Griffin, Robert Manguso

    Article

    Griffin et al Nature. 2021 Jul;595(7866):309-314. doi:

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available Since

    Dec. 15, 2023

    Availability

    Academic Institutions and Nonprofits only

15. Barcode Library 0 (BCL0)

    Pooled Library

    #179851

    Purpose

    Lentiviral barcode library that consists of 10^6 unique barcodes. Barcodes consist of 12bp degenerate region followed by two stable bases (C or G) and 4bp unique library code ACGT.

    Depositor

    Jason Moffat

    Article

    Rehman et al Cell. 2021 Jan 7;184(1):226-242.e21. doi

    Expression

    Mammalian

    Use

    Lentiviral

    Available Since

    May 12, 2022

    Availability

    Academic Institutions and Nonprofits only

16. Barcode Library 1 (BCL1)

    Pooled Library

    #179852

    Purpose

    Lentiviral barcode library that consists of 10^6 unique barcodes. Barcodes consist of 12bp degenerate region followed by two stable bases (C or G) and 4bp unique library code CCAA.

    Depositor

    Jason Moffat

    Article

    Rehman et al Cell. 2021 Jan 7;184(1):226-242.e21. doi

    Expression

    Mammalian

    Use

    Lentiviral

    Available Since

    May 12, 2022

    Availability

    Academic Institutions and Nonprofits only

17. Human genome-wide lentiviral CRISPR gRNA library version 1

    Pooled Library

    #67989

    Purpose

    Knockout library targeting 18,010 human genes. gRNAs were improved using a new design pipeline and improved gRNA scaffold.

    Depositor

    Kosuke Yusa

    Article

    Tzelepis et al Cell Rep. 2016 Oct 18;17(4):1193-1205. d

    Species

    Homo sapiens, Mus musculus, and Synthetic

    Use

    CRISPR and Lentiviral

    Available Since

    Oct. 14, 2016

    Availability

    Academic Institutions and Nonprofits only

18. Mouse genome-wide lentiviral CRISPR gRNA library version 2

    Pooled Library

    #67988

    Purpose

    Knockout library targeting 18,424 mouse genes. gRNAs were improved using a new design pipeline and improved gRNA scaffold.

    Depositor

    Kosuke Yusa

    Article

    Tzelepis et al Cell Rep. 2016 Oct 18;17(4):1193-1205. d

    Species

    Homo sapiens, Mus musculus, and Synthetic

    Use

    CRISPR and Lentiviral

    Available Since

    Oct. 14, 2016

    Availability

    Academic Institutions and Nonprofits only

19. Membrane protein gRNA library

    Pooled Library

    #113345

    Purpose

    Activation library targeting the promoters of 6,213 genes that encode at least one putative membrane-associated protein isoform.

    Depositor

    Gavin Wright

    Article

    Chong et al Genome Biol. 2018 Nov 26;19(1):205. doi:

    Species

    Homo sapiens

    Use

    Lentiviral

    Available Since

    Jan. 4, 2019

    Availability

    Academic Institutions and Nonprofits only

20. pre-associated oBC-mBC backbone (p025)

    Pooled Library

    #194097

    Purpose

    pre-associated oBC-mBC backbone (p025), can insert additional reporter constructs

    Depositor

    Jay Shendure

    Article

    Lalanne et al bioRxiv 2022.12.10.519236

    Expression

    Bacterial and Mammalian

    Use

    RNAi

    Available Since

    April 3, 2024

    Availability

    Academic Institutions and Nonprofits only