375 results

1. MYC-CRISPR

   Pooled Library

   #173195

   Purpose

   This pooled lentiviral CRISPR knockout library targets E-boxes genome-wide and can be applied for identification of essential MYC binding sites in a wide range of human cells.

   Depositor

   Agnieszka Dzikiewicz-Krawczyk

   Article

   Kazimierska et al Mol Oncol. 2023 Nov;17(11):2295-2313. do

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   Aug. 11, 2021

   Availability

   Academic Institutions and Nonprofits only

2. CRISPRi non-coding library (CRiNCL) - K562 & HeLa

   Pooled Library

   #86549

   Depositor

   Jonathan Weissman

   Article

   Liu et al Science. 2017 Jan 06. Vol. 355, Issue 63

   Available since

   March 8, 2017

   Availability

   Academic Institutions and Nonprofits only

3. plIG-123_HA-GD2-28z_CAR_TF_Library

   Pooled Library

   #207478

   Purpose

   HA-GD2-28z CAR in combination with 100 transcription factors (and related proteins) and 2 controls (GFP/RFP). Library can be used to generate HDR templates for modular pooled knockin (ModPoKI) into th

   Depositor

   Alexander Marson

   Article

   Blaeschke et al Cell. 2023 Sep 14;186(19):4216-4234.e33.

   Species

   Homo sapiens

   Use

   CRISPR

   Available since

   Jan. 26, 2024

   Availability

   Academic Institutions and Nonprofits only

4. plIG-128_HA-GD2-28z_CAR_TFxTF_Library

   Pooled Library

   #207480

   Purpose

   HA-GD2-28z CAR in combination with ~10,000 transcription factor combinations (and related proteins) and controls (GFP/RFP combinations). Library can be used to generate HDR templates for modular poole

   Depositor

   Alexander Marson

   Article

   Blaeschke et al Cell. 2023 Sep 14;186(19):4216-4234.e33.

   Use

   CRISPR

   Available since

   Jan. 26, 2024

   Availability

   Academic Institutions and Nonprofits only

5. CRISPRi non-coding library (CRiNCL) - K562, HeLa, & MCF7

   Pooled Library

   #86548

   Depositor

   Jonathan Weissman

   Article

   Liu et al Science. 2017 Jan 06. Vol. 355, Issue 63

   Available since

   March 8, 2017

   Availability

   Academic Institutions and Nonprofits only

6. DNA repair library with 1,513 sgRNAs

   Pooled Library

   #177670

   Purpose

   CRISPR-interference (CRISPRi) library designed to target 476 genes involved in DNA repair and associated processes. It contains 1,513 sgRNAs and 60 non-targeting control sgRNAs.

   Depositor

   Brittany Adamson

   Article

   Chen et al Cell. 2021 Oct 28;184(22):5635-5652.e29.

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   July 11, 2023

   Availability

   Academic Institutions and Nonprofits only

7. CRISPRi non-coding library (CRiNCL) - Unique to HeLa

   Pooled Library

   #86545

   Depositor

   Jonathan Weissman

   Article

   Liu et al Science. 2017 Jan 06. Vol. 355, Issue 63

   Available since

   March 8, 2017

   Availability

   Academic Institutions and Nonprofits only

8. iSPI_pSer_Subpool#2

   Pooled Library

   #188527

   Purpose

   Express a library of MBP-Fusion proteins containing phosphoserine at a defined position in the fusion protein

   Depositor

   Jesse Rinehart

   Article

   Gassaway et al Nat Methods. 2022 Oct 24. pii: 10.1038/s

   Expression

   Bacterial

   Species

   Homo sapiens

   Available since

   Dec. 14, 2022

   Availability

   Academic Institutions and Nonprofits only

9. Human Brunello kinome pooled library, guides 5-8 in lentiGuide-Puro backbone

   Pooled Library

   #75313

   Purpose

   Human sgRNA library in backbone lentiGuide-Puro targeting 763 kinase genes and containing 3,052 unique sgRNAs along with 100 non-targeting controls

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available since

   June 27, 2016

   Availability

   Academic Institutions and Nonprofits only

10. iSPI_pSer_Full_library Kit

    Pooled Library

    #1000000209

    Depositor

    Jesse Rinehart

    Available since

    Dec. 14, 2022

    Availability

    Academic Institutions and Nonprofits only