We narrowed to 186 results for: puro

Showing: 81 - 100 of 186 results

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TP53 MITE Library

Pooled Library

#113569

Purpose

Pooled lentiviral plasmid library containing ~8,000 single amino acid substitution and nonsense mutant variants of p53

Depositor

William Hahn, David Root

Article

Giacomelli et al Nat Genet. 2018 Oct;50(10):1381-1387. do

Expression

Mammalian

Species

Homo sapiens

Use

Lentiviral

Available Since

Jan. 4, 2019

Availability

Academic Institutions and Nonprofits only
PCT48

Pooled Library

#170392

Purpose

Barcoded plasmid library

Depositor

Jonathan Weissman

Article

Jones et al Genome Biol. 2020 Apr 14;21(1):92. doi:

Expression

Mammalian

Species

Synthetic

Use

CRISPR and Lentiviral

Available Since

Nov. 17, 2021

Availability

Academic Institutions and Nonprofits only
Mouse Toronto KnockOut (mTKO) CRISPR Library - pLCKO2

Pooled Library

#159393

Purpose

Mouse lentiviral genome-wide CRISPR library

Depositor

Jason Moffat

Article

Lawson et al Nature. 2020 Oct;586(7827):120-126. doi:

Expression

Mammalian

Species

Mus musculus

Use

CRISPR and Lentiviral

Available Since

Nov. 9, 2020

Availability

Academic Institutions and Nonprofits only
hCRISPRi-v2, Mitochondria, Trafficking, and Motility (h4), top 5 sgRNAs/gene

Pooled Library

#83974

Purpose

Human CRISPRi Pooled Library targeting Mitochondria, Trafficking, and Motility genes

Depositor

Jonathan Weissman

Article

Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

Available Since

Dec. 14, 2016

Availability

Academic Institutions and Nonprofits only
mCRISPRi-v2, Kinases, Phosphatases, and Drug Targets (m1), top 5 sgRNAs/gene

Pooled Library

#83989

Purpose

Mouse CRISPRi Pooled Library tartgeting kinsases, phosphatases and Drug Targets

Depositor

Jonathan Weissman

Article

Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

Available Since

Jan. 12, 2017

Availability

Academic Institutions and Nonprofits only
Humagne Set C

Pooled Library

#172650

Purpose

Set C contains best-ranked guides 1 and 4.

Depositor

John Doench, David Root

Article

DeWeirdt et al Nat Biotechnol. 2020 Jul 13. pii: 10.103

Expression

Mammalian

Available Since

Nov. 10, 2021

Availability

Academic Institutions and Nonprofits only
Human CRISPRa sgRNA library Calabrese in backbone XPR_502 (P65 HSF), Set B

Pooled Library

#92380

Purpose

CRISPRa

Depositor

John Doench, David Root

Article

Sanson et al Nat Commun. 2018 Dec 21;9(1):5416. doi:

Use

Lentiviral

Available Since

Aug. 3, 2017

Availability

Academic Institutions and Nonprofits only
Jacquere (split-vector)

Pooled Library

#247026

Purpose

Human genome-wide CRISPR knockout library for the use of S. pyogenes Cas9. Each gene is targeted by 3 constructs.

Depositor

John Doench, David Root

Article

Drepanos et al bioRxiv 2025.08.26.672375; doi: https://

Has Service

Lentiviral Prep

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available Since

Oct. 2, 2025

Availability

Academic Institutions and Nonprofits only
Human CRISPRi sgRNA library Dolcetto in backbone XPR_050, Set B

Pooled Library

#92386

Purpose

Crispri

Depositor

John Doench, David Root

Article

Sanson et al Nat Commun. 2018 Dec 21;9(1):5416. doi:

Use

Lentiviral

Available Since

July 13, 2018

Availability

Academic Institutions and Nonprofits only
lentiGuide-Puro-pKO-library

Pooled Library

#190744

Purpose

Targets proximal poly(A) signal sequences in genes identified to be differentially polyadenylated in the mouse B16-F10 melanoma system.

Depositor

Robert Bradley

Article

Gabel et al Nat Commun. 2024 Feb 1;15(1):959. doi: 1

Expression

Mammalian

Species

Mus musculus

Use

CRISPR, Lentiviral, and Mouse Targeting

Available Since

Feb. 2, 2024

Availability

Academic Institutions and Nonprofits only
lenti_Puro_10N barcode

Pooled Library

#238546

Purpose

Lentiviral expression of a puromycin resistance cassette liked to a random 10N barcode

Depositor

Jonathan Weissman

Article

Koblan et al Science. 2025 Jul 24:eadx3800. doi: 10.1

Expression

Mammalian

Use

Lentiviral

Available Since

Aug. 8, 2025

Availability

Academic Institutions and Nonprofits only
mU6-CR1-CRISPRiv2_hU6-CR3-NT-ctrl-guide_EF1a-PuroR-T2A-BFP

Pooled Library

#197348

Purpose

To allow for genome-wide genetic modifier screening, the library has a second fixed non-targeting control guide.

Depositor

Rebecca Voorhees, Jonathan Weissman

Article

Guna et al BMC Genomics. 2023 Oct 30;24(1):651. doi

Species

Homo sapiens

Use

Lentiviral

Available Since

May 25, 2023

Availability

Academic Institutions and Nonprofits only
mU6-CR1-CRISPRiv2_hU6-CR3-EMC2-guide_EF1a-PuroR-T2A-BFP

Pooled Library

#197349

Purpose

To allow for genome-wide genetic modifier screening, the library has a second fixed guide targeting EMC2.

Depositor

Rebecca Voorhees, Jonathan Weissman

Article

Guna et al BMC Genomics. 2023 Oct 30;24(1):651. doi

Species

Homo sapiens

Use

Lentiviral

Available Since

May 25, 2023

Availability

Academic Institutions and Nonprofits only
FNLCR CRISPRa Cell Surface

Pooled Library

#207471

Purpose

CRISPR-based activation library with guide RNAs targeting all cell surface proteins.

Depositor

Raj Chari

Article

Yang et al Sci Adv. 2024 Feb 16;10(7):eadj2445. doi

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available Since

Jan. 24, 2024

Availability

Academic Institutions and Nonprofits only
Human messenger-RBP sgRNA library

Pooled Library

#168791

Purpose

Knockout library targeting human mRNA binding proteins with 10 sgRNAs/gene.

Depositor

Martin Turner

Article

Turner et al CRISPR J. 2021 Jun;4(3):427-437. doi: 10

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available Since

July 30, 2021

Availability

Academic Institutions and Nonprofits only
DNA repair library with 1,573 sgRNAs

Pooled Library

#177663

Purpose

CRISPR-interference (CRISPRi) library of 1,573 sgRNAs targeting 476 genes encoding factors involved in DNA repair and associated processes

Depositor

Brittany Adamson

Article

Hussmann et al Cell. 2021 Oct 28;184(22):5653-5669.e25.

Species

Homo sapiens

Use

CRISPR

Available Since

July 11, 2023

Availability

Academic Institutions and Nonprofits only
Humagne Set D

Pooled Library

#172651

Purpose

Set D contains best-ranked guides 2 and 3.

Depositor

John Doench, David Root

Article

DeWeirdt et al Nat Biotechnol. 2020 Jul 13. pii: 10.103

Expression

Mammalian

Available Since

Nov. 10, 2021

Availability

Academic Institutions and Nonprofits only
Human CRISPR Knockout Pooled Library (H3)

Pooled Library

#133914

Purpose

CRISPR gRNA knockout pooled library for targeting the human genome - version H3

Depositor

Myles Brown, Xiaole Shirley Liu

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available Since

Jan. 24, 2020

Availability

Academic Institutions and Nonprofits only
mCRISPRa-v2, Cancer and Apoptosis (m2), top 5 sgRNAs/gene

Pooled Library

#83999

Purpose

Mouse CRISPRa Pooled Library targeting cancer and apoptosis genes

Depositor

Jonathan Weissman

Article

Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

Available Since

Jan. 12, 2017

Availability

Academic Institutions and Nonprofits only
hCRISPRa-v2, Stress and Proteostasis (h3), top 5 sgRNAs/gene

Pooled Library

#83982

Purpose

Human CRISPRa Pooled Library targeting stress and proteostasis genes

Depositor

Jonathan Weissman

Article

Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

Available Since

Jan. 12, 2017

Availability

Academic Institutions and Nonprofits only

Showing: 81 - 100 of 186 results

Results per page:

Sort results by:

More Filters

We narrowed to 186 results for: puro

TP53 MITE Library

PCT48

Mouse Toronto KnockOut (mTKO) CRISPR Library - pLCKO2

hCRISPRi-v2, Mitochondria, Trafficking, and Motility (h4), top 5 sgRNAs/gene

mCRISPRi-v2, Kinases, Phosphatases, and Drug Targets (m1), top 5 sgRNAs/gene

Humagne Set C

Human CRISPRa sgRNA library Calabrese in backbone XPR_502 (P65 HSF), Set B

Jacquere (split-vector)

Human CRISPRi sgRNA library Dolcetto in backbone XPR_050, Set B

lentiGuide-Puro-pKO-library

lenti_Puro_10N barcode

mU6-CR1-CRISPRiv2_hU6-CR3-NT-ctrl-guide_EF1a-PuroR-T2A-BFP

mU6-CR1-CRISPRiv2_hU6-CR3-EMC2-guide_EF1a-PuroR-T2A-BFP

FNLCR CRISPRa Cell Surface

Human messenger-RBP sgRNA library

DNA repair library with 1,573 sgRNAs

Humagne Set D

Human CRISPR Knockout Pooled Library (H3)

mCRISPRa-v2, Cancer and Apoptosis (m2), top 5 sgRNAs/gene

hCRISPRa-v2, Stress and Proteostasis (h3), top 5 sgRNAs/gene

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