966 results

1. AAV-EF1a-jGCaMP8m-WPRE (AAV Retrograde)

   Viral Prep

   #176757-AAVrg

   Purpose

   Ready-to-use AAV Retrograde particles produced from AAV-EF1a-jGCaMP8m-WPRE (#176757). In addition to the viral particles, you will also receive purified AAV-EF1a-jGCaMP8m-WPRE plasmid DNA. EF1a-driven expression of calcium sensor GCaMP8m. These AAV were produced with a retrograde serotype, which permits retrograde access to projection neurons. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Loren Looger

   Promoter

   EF1a

   Tags

   None

   Available since

   Sept. 27, 2023

   Availability

   Academic Institutions and Nonprofits only

2. pAAV-EF1a-iCreV (AAV PHP.eB)

   Viral Prep

   #140135-PHPeB

   Purpose

   Ready-to-use AAV PHP.eB particles produced from pAAV-EF1a-iCreV (#140135). In addition to the viral particles, you will also receive purified pAAV-EF1a-iCreV plasmid DNA. EF1a-driven, light-inducible iCreV recombinase for spatiotemporally precise optogenomic modifications. These AAV were produced with the PHPeB serotype, which permits efficient transduction of the central nervous system. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Hongkui Zeng

   Article

   Yao et al Nat Methods. 2020 Mar 23. pii: 10.1038/s

   Promoter

   EF1a

   Tags

   None

   Available since

   Sept. 15, 2021

   Availability

   Academic Institutions and Nonprofits only

3. pAAV-hSynapsin1-axon-jGCaMP8f-P2A-mRuby3 (AAV9)

   Viral Prep

   #172923-AAV9

   Purpose

   Ready-to-use AAV9 particles produced from pAAV-hSynapsin1-axon-jGCaMP8f-P2A-mRuby3 (#172923). In addition to the viral particles, you will also receive purified pAAV-hSynapsin1-axon-jGCaMP8f-P2A-mRuby3 plasmid DNA. hSyn-driven expression of calcium sensor jGCaMP8f in axons with cytosolic expression of mRuby3. These AAV preparations are suitable purity for injection into animals.

   Depositor

   GENIE Project

   Promoter

   Syn

   Tags

   mRuby3

   Available since

   Aug. 24, 2023

   Availability

   Academic Institutions and Nonprofits only

4. pAAV-CAG-GFP (AAV9-X1.1)

   Viral Prep

   #37825-AAV9-X1.1

   Purpose

   Ready-to-use AAV9-X1.1 particles produced from pAAV-CAG-GFP (#37825). In addition to the viral particles, you will also receive purified pAAV-CAG-GFP plasmid DNA. CAG-driven GFP expression. These AAV were produced with the AAV9-X1.1 serotype, which permits efficient transduction of brain endothelial cells. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Edward Boyden

   Promoter

   CAG

   Tags

   GFP

   Available since

   Sept. 27, 2024

   Availability

   Academic Institutions and Nonprofits only

5. pGP-AAV-syn-jGCaMP7f-WPRE (AAV8)

   Viral Prep

   #104488-AAV8

   Purpose

   Ready-to-use AAV8 particles produced from pGP-AAV-syn-jGCaMP7f-WPRE (#104488). In addition to the viral particles, you will also receive purified pGP-AAV-syn-jGCaMP7f-WPRE plasmid DNA. Synapsin-driven GCaMP7f calcium sensor. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Douglas Kim, GENIE Project

   Article

   Dana et al Nat Methods. 2019 Jul;16(7):649-657. doi

   Promoter

   Syn

   Tags

   None

   Available since

   May 29, 2019

   Availability

   Academic Institutions and Nonprofits only

6. pAAV-Ef1a-Con/Foff 2.0-oScarlet (AAV8)

   Viral Prep

   #137137-AAV8

   Purpose

   Ready-to-use AAV8 particles produced from pAAV-Ef1a-Con/Foff 2.0-oScarlet (#137137). In addition to the viral particles, you will also receive purified pAAV-Ef1a-Con/Foff 2.0-oScarlet plasmid DNA. EF1a-driven, Cre-dependent expression of oScarlet (inhibited in presence of Flp). These AAV preparations are suitable purity for injection into animals.

   Depositor

   INTRSECT 2.0 Project, Karl Deisseroth

   Article

   Fenno et al Neuron. 2020 Jun 20. pii: S0896-6273(20)

   Promoter

   EF1a

   Tags

   oScarlet (Cre-dependent)

   Available since

   April 8, 2021

   Availability

   Academic Institutions and Nonprofits only

7. AAV phSyn1(S)-DreO-bGHpA (AAV5)

   Viral Prep

   #50363-AAV5

   Purpose

   Ready-to-use AAV5 particles produced from AAV phSyn1(S)-DreO-bGHpA (#50363). In addition to the viral particles, you will also receive purified AAV phSyn1(S)-DreO-bGHpA plasmid DNA. hSyn-driven Dre recombinase expression. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Hongkui Zeng

   Article

   Madisen et al Neuron. 2015 Mar 4;85(5):942-58. doi: 10

   Promoter

   Syn

   Tags

   None

   Available since

   May 29, 2019

   Availability

   Academic Institutions and Nonprofits only

8. AiP15140: pAAV-AiE0873m_3xC2-minBG-CoChR-EGFP-WPRE3-BGHpA (Alias: CN5140) (AAV PHP.eB)

   Viral Prep

   #214869-PHPeB

   Purpose

   Ready-to-use AAV PHP.eB particles produced from AiP15140: pAAV-AiE0873m_3xC2-minBG-CoChR-EGFP-WPRE3-BGHpA (Alias: CN5140) (#214869). In addition to the viral particles, you will also receive purified AiP15140: pAAV-AiE0873m_3xC2-minBG-CoChR-EGFP-WPRE3-BGHpA (Alias: CN5140) plasmid DNA. minBG-driven expression of CoChR-EGFP in striatal cholinergic neurons. These AAV were produced with the PHPeB serotype, which permits efficient transduction of the central nervous system. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Jonathan Ting, The Allen Institute for Brain Science

   Article

   Hunker et al Neuron. 2025 May 21;113(10):1507-1524.e1

   Promoter

   Tags

   EGFP

   Available since

   Nov. 13, 2024

   Availability

   Academic Institutions and Nonprofits only

9. pAAV-nEF-Con/Foff 2.0-Arch3.3-EYFP (AAV8)

   Viral Prep

   #137149-AAV8

   Purpose

   Ready-to-use AAV8 particles produced from pAAV-nEF-Con/Foff 2.0-Arch3.3-EYFP (#137149). In addition to the viral particles, you will also receive purified pAAV-nEF-Con/Foff 2.0-Arch3.3-EYFP plasmid DNA. nEF-driven, Cre-dependent expression of Arch3.3-EYFP (inhibited in presence of Flp) for optogenetic inhibition. These AAV preparations are suitable purity for injection into animals.

   Depositor

   INTRSECT 2.0 Project, Karl Deisseroth

   Article

   Fenno et al Neuron. 2020 Jun 20. pii: S0896-6273(20)

   Promoter

   nEF

   Tags

   EYFP (Cre-dependent)

   Available since

   May 6, 2021

   Availability

   Academic Institutions and Nonprofits only

10. AiP13987: pAAV-AiE0452h_3xC2-minBG-jRGECO1a-WPRE3-BGHpA (Alias: CN3987) (AAV PHP.eB)

    Viral Prep

    #214851-PHPeB

    Purpose

    Ready-to-use AAV PHP.eB particles produced from AiP13987: pAAV-AiE0452h_3xC2-minBG-jRGECO1a-WPRE3-BGHpA (Alias: CN3987) (#214851). In addition to the viral particles, you will also receive purified AiP13987: pAAV-AiE0452h_3xC2-minBG-jRGECO1a-WPRE3-BGHpA (Alias: CN3987) plasmid DNA. minBG-driven expression of jRGECO1a in striatal indirect pathway medium spiny neurons (D2 MSNs). These AAV were produced with the PHPeB serotype, which permits efficient transduction of the central nervous system. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Jonathan Ting, The Allen Institute for Brain Science

    Article

    Hunker et al Neuron. 2025 May 21;113(10):1507-1524.e1

    Promoter

    Tags

    None

    Available since

    Jan. 27, 2025

    Availability

    Academic Institutions and Nonprofits only

11. pAAV-CAG-eYFP (AAV Retrograde)

    Viral Prep

    #104055-AAVrg

    Purpose

    Ready-to-use AAV Retrograde particles produced from pAAV-CAG-eYFP (#104055). In addition to the viral particles, you will also receive purified pAAV-CAG-eYFP plasmid DNA. CAG-driven eYFP expression control. These AAV were produced with a retrograde serotype, which permits retrograde access to projection neurons. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Viviana Gradinaru

    Article

    Challis et al Nat Protoc. 2019 Feb;14(2):379-414. doi:

    Promoter

    CAG

    Tags

    EYFP

    Available since

    Jan. 6, 2022

    Availability

    Academic Institutions and Nonprofits only

12. pENN.AAV.CB7.CI.eGFP.WPRE.rBG (AAV1)

    Viral Prep

    #105542-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pENN.AAV.CB7.CI.eGFP.WPRE.rBG (#105542). In addition to the viral particles, you will also receive purified pENN.AAV.CB7.CI.eGFP.WPRE.rBG plasmid DNA. CB7-driven eGFP. These AAV preparations are suitable purity for injection into animals.

    Depositor

    James M. Wilson

    Promoter

    CB7

    Tags

    EGFP

    Available since

    May 8, 2018

    Availability

    Academic Institutions and Nonprofits only

13. pAAV-hSynapsin1-axon-GCaMP6s-P2A-mRuby3 (AAV5)

    Viral Prep

    #112005-AAV5

    Purpose

    Ready-to-use AAV5 particles produced from pAAV-hSynapsin1-axon-GCaMP6s-P2A-mRuby3 (#112005). In addition to the viral particles, you will also receive purified pAAV-hSynapsin1-axon-GCaMP6s-P2A-mRuby3 plasmid DNA. Synapsin-driven, axon-targeted GCaMP6s calcium sensor and mRuby3 expression. The mRuby3 will be a separate protein (not a fusion protein). These AAV preparations are suitable purity for injection into animals.

    Depositor

    Lin Tian

    Article

    Broussard et al Nat Neurosci. 2018 Sep;21(9):1272-1280.

    Promoter

    Syn

    Tags

    mRuby3

    Available since

    Dec. 4, 2018

    Availability

    Academic Institutions and Nonprofits only

14. pSMAL-CellTag-V3 (Concentrated Lentiviral Prep)

    Viral Prep

    #115645-LVC

    Purpose

    Ready-to-use Concentrated Lentiviral Prep particles produced from pSMAL-CellTag-V3 (#115645). In addition to the viral particles, you will also receive purified pSMAL-CellTag-V3 plasmid DNA. Ready-to-use lentiviral particles carrying version 3 of the CellTag barcoding library to combinatorially index cells for single-cell analysis of clonal dynamics.

    Depositor

    Samantha Morris

    Article

    Biddy et al Nature. 2018 Dec;564(7735):219-224. doi:

    Promoter

    Minimal CMV

    Tags

    EGFP

    Available since

    Oct. 29, 2019

    Availability

    Academic Institutions and Nonprofits only

15. pAAV-Ef1a-fDIO EYFP (AAV Retrograde)

    Viral Prep

    #55641-AAVrg

    Purpose

    Ready-to-use AAV Retrograde particles produced from pAAV-Ef1a-fDIO EYFP (#55641). In addition to the viral particles, you will also receive purified pAAV-Ef1a-fDIO EYFP plasmid DNA. EF1a-driven, Flp-dependent expression of EYFP. These AAV were produced with a retrograde serotype, which permits retrograde access to projection neurons. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Karl Deisseroth

    Article

    Fenno et al Nat Methods. 2014 Jul;11(7):763-72. doi:

    Promoter

    EF1a

    Tags

    EYFP (Flp-dependent)

    Available since

    Oct. 21, 2024

    Availability

    Academic Institutions and Nonprofits only

16. pAAV-hSynapsin1-axon-GCaMP6m (AAV9)

    Viral Prep

    #111261-AAV9

    Purpose

    Ready-to-use AAV9 particles produced from pAAV-hSynapsin1-axon-GCaMP6m (#111261). In addition to the viral particles, you will also receive purified pAAV-hSynapsin1-axon-GCaMP6m plasmid DNA. Synapsin-driven expression of calcium sensor GCaMP6m in axons. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Lin Tian

    Article

    Broussard et al Nat Neurosci. 2018 Sep;21(9):1272-1280.

    Promoter

    Syn

    Tags

    None

    Available since

    Sept. 27, 2023

    Availability

    Academic Institutions and Nonprofits only

17. pAAV-CAG-FLEX-Archon1-KGC-EGFP-ER2 (AAV5)

    Viral Prep

    #108422-AAV5

    Purpose

    Ready-to-use AAV5 particles produced from pAAV-CAG-FLEX-Archon1-KGC-EGFP-ER2 (#108422). In addition to the viral particles, you will also receive purified pAAV-CAG-FLEX-Archon1-KGC-EGFP-ER2 plasmid DNA. CAG-driven, Cre dependent Archon1, an opsin-based fluorescent voltage indicator, fused to EGFP. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Edward Boyden

    Article

    Piatkevich et al Nat Chem Biol. 2018 Feb 26. pii: 10.1038

    Promoter

    CAG

    Tags

    EGFP (Cre-dependent)

    Available since

    Sept. 17, 2018

    Availability

    Academic Institutions and Nonprofits only

18. pGP-AAV-CAG-FLEX-jGCaMP8m-WPRE (AAV Retrograde)

    Viral Prep

    #162381-AAVrg

    Purpose

    Ready-to-use AAV Retrograde particles produced from pGP-AAV-CAG-FLEX-jGCaMP8m-WPRE (#162381). In addition to the viral particles, you will also receive purified pGP-AAV-CAG-FLEX-jGCaMP8m-WPRE plasmid DNA. CAG-driven, Cre-dependent expression of calcium sensor GCaMP8m (faster, more sensitive). These AAV were produced with a retrograde serotype, which permits retrograde access to projection neurons. These AAV preparations are suitable purity for injection into animals.

    Depositor

    GENIE Project

    Article

    Zhang et al Janelia Research Campus, Online Resource

    Promoter

    CAG

    Tags

    None

    Available since

    Jan. 6, 2022

    Availability

    Academic Institutions and Nonprofits only

19. pAAV-ihSyn1-DIO-tTA (AAV1)

    Viral Prep

    #99121-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pAAV-ihSyn1-DIO-tTA (#99121). In addition to the viral particles, you will also receive purified pAAV-ihSyn1-DIO-tTA plasmid DNA. Cre-dependent expression of the tet-off transactivator from an inducible synapsin promoter. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Viviana Gradinaru

    Article

    Chan et al Nat Neurosci. 2017 Aug;20(8):1172-1179.

    Promoter

    ihSyn1

    Tags

    None

    Available since

    April 4, 2019

    Availability

    Academic Institutions and Nonprofits only

20. AAV-EF1a-jGCaMP8s-WPRE (AAV9)

    Viral Prep

    #176758-AAV9

    Purpose

    Ready-to-use AAV9 particles produced from AAV-EF1a-jGCaMP8s-WPRE (#176758). In addition to the viral particles, you will also receive purified AAV-EF1a-jGCaMP8s-WPRE plasmid DNA. EF1a-driven expression of calcium sensor GCaMP8s. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Loren Looger

    Promoter

    EF1a

    Tags

    None

    Available since

    Feb. 24, 2023

    Availability

    Academic Institutions and Nonprofits only

21. AAV-EF1a-jGCaMP8m-WPRE (AAV1)

    Viral Prep

    #176757-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from AAV-EF1a-jGCaMP8m-WPRE (#176757). In addition to the viral particles, you will also receive purified AAV-EF1a-jGCaMP8m-WPRE plasmid DNA. EF1a-driven expression of calcium sensor GCaMP8m. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Loren Looger

    Promoter

    EF1a

    Tags

    None

    Available since

    July 12, 2023

    Availability

    Academic Institutions and Nonprofits only

22. pAAV-hSynapsin1-axon-jGCaMP8m-P2A-mRuby3 (AAV9)

    Viral Prep

    #172922-AAV9

    Purpose

    Ready-to-use AAV9 particles produced from pAAV-hSynapsin1-axon-jGCaMP8m-P2A-mRuby3 (#172922). In addition to the viral particles, you will also receive purified pAAV-hSynapsin1-axon-jGCaMP8m-P2A-mRuby3 plasmid DNA. hSyn-driven expression of jGCaMP8m in axons with cytosolic expression of mRuby3. These AAV preparations are suitable purity for injection into animals.

    Depositor

    GENIE Project

    Promoter

    Syn

    Tags

    None

    Available since

    Aug. 24, 2023

    Availability

    Academic Institutions and Nonprofits only

23. pENN.AAV.EF1a.eGFP.WPRE.rBG (AAV PHP.eB)

    Viral Prep

    #105547-PHPeB

    Purpose

    Ready-to-use AAV PHP.eB particles produced from pENN.AAV.EF1a.eGFP.WPRE.rBG (#105547). In addition to the viral particles, you will also receive purified pENN.AAV.EF1a.eGFP.WPRE.rBG plasmid DNA. EF1a-driven EGFP expression. These AAV were produced with the PHPeB serotype, which permits efficient transduction of the central nervous system. These AAV preparations are suitable purity for injection into animals.

    Depositor

    James M. Wilson

    Promoter

    EF1a

    Tags

    EGFP

    Available since

    Feb. 16, 2024

    Availability

    Academic Institutions and Nonprofits only

24. pAAV-CAG-dLight1.1 (AAV1)

    Viral Prep

    #111067-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pAAV-CAG-dLight1.1 (#111067). In addition to the viral particles, you will also receive purified pAAV-CAG-dLight1.1 plasmid DNA. CAG-driven expression of dLight1.1 dopamine sensor. This sensor is recommended for photometry in vivo. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Lin Tian

    Article

    Patriarchi et al Science. 2018 Jun 29;360(6396). pii: sci

    Promoter

    Tags

    None

    Available since

    March 12, 2021

    Availability

    Academic Institutions and Nonprofits only

25. pOTTC1032 - pAAV EF1a Nuc-flox(mCherry)-EGFP (AAV1)

    Viral Prep

    #112677-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pOTTC1032 - pAAV EF1a Nuc-flox(mCherry)-EGFP (#112677). In addition to the viral particles, you will also receive purified pOTTC1032 - pAAV EF1a Nuc-flox(mCherry)-EGFP plasmid DNA. EF1a-driven, Cre-dependent color switch. This AAV directs expression of nuclear mCherry in the absence of Cre. In the presence of Cre, nuclear EGFP (and not mCherry) will be expressed. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Brandon Harvey

    Article

    Back et al Neuron. 2019 Feb 8. pii: S0896-6273(19)3

    Promoter

    EF1a

    Tags

    mCherry (Cre-negative cells), EGFP (Cre-positive cells)

    Available since

    Dec. 2, 2019

    Availability

    Academic Institutions and Nonprofits only

26. pGP-AAV-CAG-FLEX-jGCaMP7s-WPRE (AAV1)

    Viral Prep

    #104495-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pGP-AAV-CAG-FLEX-jGCaMP7s-WPRE (#104495). In addition to the viral particles, you will also receive purified pGP-AAV-CAG-FLEX-jGCaMP7s-WPRE plasmid DNA. CAG-driven, Cre-dependent GCaMP7s calcium sensor. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Douglas Kim, GENIE Project

    Article

    Dana et al Nat Methods. 2019 Jul;16(7):649-657. doi

    Promoter

    CAG

    Tags

    None

    Available since

    Aug. 24, 2020

    Availability

    Academic Institutions and Nonprofits only

27. pAAV-S5E2-Gq-P2A-dTomato (AAV PHP.eB)

    Viral Prep

    #135635-PHPeB

    Purpose

    Ready-to-use AAV PHP.eB particles produced from pAAV-S5E2-Gq-P2A-dTomato (#135635). In addition to the viral particles, you will also receive purified pAAV-S5E2-Gq-P2A-dTomato plasmid DNA. Expression of Gq-DREADD and dTomato (physically separate) under the control of the E2 regulatory element. These AAV were produced with the PHPeB serotype, which permits efficient transduction of the central nervous system. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Jordane Dimidschstein

    Article

    Vormstein-Schneider et al Nat Neurosci. 2020 Dec;23(12):1629-1636.

    Promoter

    Tags

    dTomato (physically separate, not a fusion protein)

    Available since

    Aug. 27, 2021

    Availability

    Academic Institutions and Nonprofits only

28. pAAV-EF1a-C-CreintG (AAV1)

    Viral Prep

    #69571-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pAAV-EF1a-C-CreintG (#69571). In addition to the viral particles, you will also receive purified pAAV-EF1a-C-CreintG plasmid DNA. EF1a-driven expression of optimized C-terminal component of Cre recombinase dependent on GFP (Cre-DOG OPT); to be coinjected with pAAV-EF1a-N-CretrcintG (Addgene catalog# 69570) and GFP (or for use with transgenic GFP animals). These AAV preparations are suitable purity for injection into animals.

    Depositor

    Connie Cepko

    Article

    Tang et al Nat Neurosci. 2015 Sep;18(9):1334-41. do

    Promoter

    EF1a

    Tags

    None

    Available since

    Feb. 19, 2020

    Availability

    Academic Institutions and Nonprofits only

29. pAAV-EF1a-N-CretrcintG (AAV1)

    Viral Prep

    #69570-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pAAV-EF1a-N-CretrcintG (#69570). In addition to the viral particles, you will also receive purified pAAV-EF1a-N-CretrcintG plasmid DNA. EF1a-driven expression of optimized N-terminal component of Cre recombinase dependent on GFP (Cre-DOG OPT); to be coinjected with pAAV-EF1a-C-CreintG (Addgene catalog# 69571) and GFP (or for use with transgenic GFP animals). These AAV preparations are suitable purity for injection into animals.

    Depositor

    Connie Cepko

    Article

    Tang et al Nat Neurosci. 2015 Sep;18(9):1334-41. do

    Promoter

    EF1a

    Tags

    None

    Available since

    Feb. 19, 2020

    Availability

    Academic Institutions and Nonprofits only

30. pAAV-hSyn-GRAB_NE1h (AAV Retrograde)

    Viral Prep

    #123309-AAVrg

    Purpose

    Ready-to-use AAV Retrograde particles produced from pAAV-hSyn-GRAB_NE1h (#123309). In addition to the viral particles, you will also receive purified pAAV-hSyn-GRAB_NE1h plasmid DNA. hSyn-driven expression of GRAB-NE1h norepinephrine sensor in neurons. These AAV were produced with a retrograde serotype, which permits retrograde access to projection neurons. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Yulong Li

    Article

    Feng et al Neuron. 2019 May 22;102(4):745-761.e8. d

    Promoter

    Syn

    Tags

    None

    Available since

    June 22, 2020

    Availability

    Academic Institutions and Nonprofits only

31. pAAV-nEF-Con/Foff 2.0-iC++-EYFP (AAV8)

    Viral Prep

    #137156-AAV8

    Purpose

    Ready-to-use AAV8 particles produced from pAAV-nEF-Con/Foff 2.0-iC++-EYFP (#137156). In addition to the viral particles, you will also receive purified pAAV-nEF-Con/Foff 2.0-iC++-EYFP plasmid DNA. nEF-driven, Cre-dependent expression of chloride-conducting channelrhodopsin iC++-EYFP (inhibited in presence of Flp) for optogenetic inhibition. These AAV preparations are suitable purity for injection into animals.

    Depositor

    INTRSECT 2.0 Project, Karl Deisseroth

    Article

    Fenno et al Neuron. 2020 Jun 20. pii: S0896-6273(20)

    Promoter

    nEF

    Tags

    EYFP (Cre-dependent)

    Available since

    Nov. 25, 2020

    Availability

    Academic Institutions and Nonprofits only

32. pENN.AAV.GFAP.iGluSnFr.WPRE.SV40 (AAV5)

    Viral Prep

    #98930-AAV5

    Purpose

    Ready-to-use AAV5 particles produced from pENN.AAV.GFAP.iGluSnFr.WPRE.SV40 (#98930). In addition to the viral particles, you will also receive purified pENN.AAV.GFAP.iGluSnFr.WPRE.SV40 plasmid DNA. GFAP-driven glutamate sensor. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Loren Looger

    Article

    Marvin et al Nat Methods. 2013 Feb;10(2):162-70. doi:

    Promoter

    GFAP

    Tags

    None

    Available since

    Feb. 27, 2018

    Availability

    Academic Institutions and Nonprofits only

33. AAV-mDlx-jGCaMP8f-WPRE (AAV9)

    Viral Prep

    #176753-AAV9

    Purpose

    Ready-to-use AAV9 particles produced from AAV-mDlx-jGCaMP8f-WPRE (#176753). In addition to the viral particles, you will also receive purified AAV-mDlx-jGCaMP8f-WPRE plasmid DNA. mDlx enhancer-driven expression of calcium sensor GCaMP8f in GABA-ergic interneurons. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Loren Looger

    Promoter

    mDlx

    Tags

    None

    Available since

    Feb. 24, 2023

    Availability

    Academic Institutions and Nonprofits only

34. pAAV-hSyn-GRAB_OTmut (AAV1)

    Viral Prep

    #185388-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pAAV-hSyn-GRAB_OTmut (#185388). In addition to the viral particles, you will also receive purified pAAV-hSyn-GRAB_OTmut plasmid DNA. hSyn-driven expression of the genetically-encoded fluorescent oxytocin(OT) control sensor GRAB_OTmut in neurons. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Yulong Li

    Article

    Qian et al Nat Biotechnol. 2023 Jan 2. doi: 10.1038

    Promoter

    Syn

    Tags

    None

    Available since

    Oct. 21, 2024

    Availability

    Academic Institutions and Nonprofits only

35. AAV-CamKIIa-jGCaMP8f-WPRE (AAV Retrograde)

    Viral Prep

    #176750-AAVrg

    Purpose

    Ready-to-use AAV Retrograde particles produced from AAV-CamKIIa-jGCaMP8f-WPRE (#176750). In addition to the viral particles, you will also receive purified AAV-CamKIIa-jGCaMP8f-WPRE plasmid DNA. CamKIIa-driven expression of calcium sensor GCaMP8f. These AAV were produced with a retrograde serotype, which permits retrograde access to projection neurons. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Loren Looger

    Promoter

    CamKIIalpha

    Tags

    None

    Available since

    July 21, 2023

    Availability

    Academic Institutions and Nonprofits only

36. pAAV-double floxed-eNpHR-EYFP-WPRE-pA (AAV9)

    Viral Prep

    #20949-AAV9

    Purpose

    Ready-to-use AAV9 particles produced from pAAV-double floxed-eNpHR-EYFP-WPRE-pA (#20949). In addition to the viral particles, you will also receive purified pAAV-double floxed-eNpHR-EYFP-WPRE-pA plasmid DNA. EF1a-driven, cre-dependent eNpHR EYFP for optogenetic inhibition. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Karl Deisseroth

    Promoter

    EF1a

    Tags

    EYFP (Cre-dependent)

    Available since

    July 12, 2018

    Availability

    Academic Institutions and Nonprofits only

37. pAAV-CAG-Flex-mRuby2-GSG-P2A-GCaMP6s-WPRE-pA (AAV1)

    Viral Prep

    #68717-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pAAV-CAG-Flex-mRuby2-GSG-P2A-GCaMP6s-WPRE-pA (#68717). In addition to the viral particles, you will also receive purified pAAV-CAG-Flex-mRuby2-GSG-P2A-GCaMP6s-WPRE-pA plasmid DNA. CAG-driven, Cre dependent, GCaMP6s calcium sensor and bicistronic, physically separate mRuby2 expression. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Mark Huebener, Tobias Rose, Tobias Bonhoeffer

    Article

    Rose et al Science. 2016 Jun 10;352(6291):1319-22.

    Promoter

    CAG-FLEX

    Tags

    mRuby2 (Cre-dependent)

    Available since

    May 4, 2018

    Availability

    Academic Institutions and Nonprofits only

38. AAV-CAG-jGCaMP8f-WPRE (AAV1)

    Viral Prep

    #179254-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from AAV-CAG-jGCaMP8f-WPRE (#179254). In addition to the viral particles, you will also receive purified AAV-CAG-jGCaMP8f-WPRE plasmid DNA. CAG-driven expression of calcium sensor GCaMP8f. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Loren Looger

    Promoter

    CAG

    Tags

    None

    Available since

    May 18, 2023

    Availability

    Academic Institutions and Nonprofits only

39. pENN.AAV.CB7.CI.eGFP.WPRE.rBG (AAV9)

    Viral Prep

    #105542-AAV9

    Purpose

    Ready-to-use AAV9 particles produced from pENN.AAV.CB7.CI.eGFP.WPRE.rBG (#105542). In addition to the viral particles, you will also receive purified pENN.AAV.CB7.CI.eGFP.WPRE.rBG plasmid DNA. CB7-driven eGFP. These AAV preparations are suitable purity for injection into animals.

    Depositor

    James M. Wilson

    Promoter

    CB7

    Tags

    EGFP

    Available since

    Aug. 2, 2018

    Availability

    Academic Institutions and Nonprofits only

40. pGP-AAV-syn-iGABASnFR2(no bind)-WPRE (AAV5)

    Viral Prep

    #218876-AAV5

    Purpose

    Ready-to-use AAV5 particles produced from pGP-AAV-syn-iGABASnFR2(no bind)-WPRE (#218876). In addition to the viral particles, you will also receive purified pGP-AAV-syn-iGABASnFR2(no bind)-WPRE plasmid DNA. Syn-driven expression of the improved GABA sensor control iGABASnFR2(no bind) (no change in fluorescence). These AAV preparations are suitable purity for injection into animals.

    Depositor

    GENIE Project

    Article

    Kolb et al bioRxiv 2025.03.25.644953

    Promoter

    Syn

    Tags

    None

    Available since

    Sept. 27, 2024

    Availability

    Academic Institutions and Nonprofits only

41. pAAV.hSynap-FLEX.SF-iGluSnFR.A184V (AAV1)

    Viral Prep

    #106181-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pAAV.hSynap-FLEX.SF-iGluSnFR.A184V (#106181). In addition to the viral particles, you will also receive purified pAAV.hSynap-FLEX.SF-iGluSnFR.A184V plasmid DNA. Synapsin-driven, Cre-dependent expression of glutamate sensor iGluSnFR (medium affinity). These AAV preparations are suitable purity for injection into animals.

    Depositor

    Loren Looger

    Article

    Marvin et al Nat Methods. 2018 Nov;15(11):936-939. do

    Promoter

    Syn

    Tags

    None

    Available since

    March 19, 2021

    Availability

    Academic Institutions and Nonprofits only

42. pOTTC1032 - pAAV EF1a Nuc-flox(mCherry)-EGFP (AAV8)

    Viral Prep

    #112677-AAV8

    Purpose

    Ready-to-use AAV8 particles produced from pOTTC1032 - pAAV EF1a Nuc-flox(mCherry)-EGFP (#112677). In addition to the viral particles, you will also receive purified pOTTC1032 - pAAV EF1a Nuc-flox(mCherry)-EGFP plasmid DNA. EF1a-driven, Cre-dependent color switch. This AAV directs expression of nuclear mCherry in the absence of Cre. In the presence of Cre, nuclear EGFP (and not mCherry) will be expressed. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Brandon Harvey

    Article

    Back et al Neuron. 2019 Feb 8. pii: S0896-6273(19)3

    Promoter

    EF1a

    Tags

    mCherry (Cre-negative cells), EGFP (Cre-positive cells)

    Available since

    Sept. 8, 2020

    Availability

    Academic Institutions and Nonprofits only

43. pAAV-synapsin-HaloCaMP1a-EGFP (AAV1)

    Viral Prep

    #138327-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pAAV-synapsin-HaloCaMP1a-EGFP (#138327). In addition to the viral particles, you will also receive purified pAAV-synapsin-HaloCaMP1a-EGFP plasmid DNA. Synapsin-driven HaloCaMP1a, a far-red calcium sensor, fused to EGFP. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Eric Schreiter

    Article

    Deo et al Nat Chem Biol. 2021 Jun;17(6):718-723. d

    Promoter

    Syn

    Tags

    EGFP

    Available since

    Sept. 15, 2021

    Availability

    Academic Institutions and Nonprofits only

44. pAAV-S5E2-C1V1-eYFP (AAV9)

    Viral Prep

    #135633-AAV9

    Purpose

    Ready-to-use AAV9 particles produced from pAAV-S5E2-C1V1-eYFP (#135633). In addition to the viral particles, you will also receive purified pAAV-S5E2-C1V1-eYFP plasmid DNA. Expression of red-shifted opsin C1V1 fused to EYFP under the control of the E2 regulatory element. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Jordane Dimidschstein

    Article

    Vormstein-Schneider et al Nat Neurosci. 2020 Dec;23(12):1629-1636.

    Promoter

    Tags

    EYFP

    Available since

    Aug. 27, 2021

    Availability

    Academic Institutions and Nonprofits only

45. AAV pEF1a-DIO-FLPo-WPRE-hGHpA (AAV2)

    Viral Prep

    #87306-AAV2

    Purpose

    Ready-to-use AAV2 particles produced from AAV pEF1a-DIO-FLPo-WPRE-hGHpA (#87306). In addition to the viral particles, you will also receive purified AAV pEF1a-DIO-FLPo-WPRE-hGHpA plasmid DNA. EF1a-driven, Cre dependent expression of the site-specific recombinase FlpO. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Li Zhang

    Article

    Zingg et al Neuron. 2017 Jan 4;93(1):33-47. doi: 10.

    Promoter

    EF1a

    Tags

    None

    Available since

    Aug. 24, 2020

    Availability

    Academic Institutions and Nonprofits only

46. pAAV-CaMKIIa-hChR2(E123A)-mCherry (AAV9)

    Viral Prep

    #35506-AAV9

    Purpose

    Ready-to-use AAV9 particles produced from pAAV-CaMKIIa-hChR2(E123A)-mCherry (#35506). In addition to the viral particles, you will also receive purified pAAV-CaMKIIa-hChR2(E123A)-mCherry plasmid DNA. CaMKIIa-driven, humanized channelrhodopsin E123A mutant fused to mCherry for optogenetic activation. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Karl Deisseroth

    Article

    Mattis et al Nat Methods. 2011 Dec 18;9(2):159-72. do

    Promoter

    CaMKII

    Tags

    mCherry

    Available since

    March 30, 2018

    Availability

    Academic Institutions and Nonprofits only

47. AAV-CAG-jGCaMP8m-WPRE (AAV Retrograde)

    Viral Prep

    #179255-AAVrg

    Purpose

    Ready-to-use AAV Retrograde particles produced from AAV-CAG-jGCaMP8m-WPRE (#179255). In addition to the viral particles, you will also receive purified AAV-CAG-jGCaMP8m-WPRE plasmid DNA. CAG-driven expression of calcium sensor GCaMP8m. These AAV were produced with a retrograde serotype, which permits retrograde access to projection neurons. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Loren Looger

    Promoter

    CAG

    Tags

    None

    Available since

    March 18, 2024

    Availability

    Academic Institutions and Nonprofits only

48. pAAV-hSynapsin1-GCaMP6s-P2A-mRuby3 (AAV9)

    Viral Prep

    #112007-AAV9

    Purpose

    Ready-to-use AAV9 particles produced from pAAV-hSynapsin1-GCaMP6s-P2A-mRuby3 (#112007). In addition to the viral particles, you will also receive purified pAAV-hSynapsin1-GCaMP6s-P2A-mRuby3 plasmid DNA. hSyn-driven expression of calcium sensor GCaMP6s and bicistronic mRuby3. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Lin Tian

    Article

    Broussard et al Nat Neurosci. 2018 Sep;21(9):1272-1280.

    Promoter

    Syn

    Tags

    mRuby3

    Available since

    Feb. 14, 2022

    Availability

    Academic Institutions and Nonprofits only

49. pAAV.CAG.iAChSnFR (AAV1)

    Viral Prep

    #137955-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pAAV.CAG.iAChSnFR (#137955). In addition to the viral particles, you will also receive purified pAAV.CAG.iAChSnFR plasmid DNA. CAG-driven iAChSnFR acetylcholine sensor. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Loren Looger

    Article

    Borden et al bioRxiv 2020

    Promoter

    CAG

    Tags

    None

    Available since

    Oct. 28, 2021

    Availability

    Academic Institutions and Nonprofits only

50. pAAV CD68-hM4D(Gi)-mCherry (AAV1)

    Viral Prep

    #75033-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pAAV CD68-hM4D(Gi)-mCherry (#75033). In addition to the viral particles, you will also receive purified pAAV CD68-hM4D(Gi)-mCherry plasmid DNA. CD68-driven hM4D(Gi) receptor with an mCherry reporter for CNO-induced microglial inhibition. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Bryan Roth

    Article

    Grace et al Proc Natl Acad Sci U S A. 2016 Jun 14;11

    Promoter

    CD68

    Tags

    mCherry

    Available since

    March 27, 2019

    Availability

    Academic Institutions and Nonprofits only