We narrowed to 676 results for: RON

... related to cell-to-cell communications and environmental sensing. Sensing and Signaling Plasmids Search...

...engineering: A new stem cell initiative from the NIH. Neuron . 2021 Apr 7;109(7):1080-1083. PMID: 33831364 (...

...treatment of neuroendocrine cancers. As such, NETRF strongly encourages its funded scientists to make their...

...double-strand break (DSB) that is repaired using error-prone non-homologous end joining (NHEJ). Double nicking...

... almost unidirectional insertions, but are more prone to off-target insertions. CASTs are most often used...

...blocks the progression of the RNA polymerase, thus strongly decreasing the expression level. Mismatches between...

... the presynaptic and postsynaptic membranes at neuronal synapses. Image credit: IPI Browse Neurexin and...

...transient transgene expression.They can induce a strong immunogenic response, useful for clinical applications...

...Acknowledgement (RSA). This form can be completed electronically by the scientist who will be using the materials...

...Use our chemogenetics AAV to chemically induce neuronal activity in specific cell types. See our Chemogenetics...

...Choi J, Jones S, Ghebranious N, Igelmann H, Lu X, Soron G, Cooper B, Brayton C, Park SH, Thompson T, Karsenty...

...new technology, and we hope to continue to have a strong scientific partnership with both the labs that ...

...expression level and maturation time, and other environmental factors. When designing your experiment, be ...

...construct ; pMA122 (negative selection marker); pGH8 (neuronal co-injection marker); pCFJ104 (body wall muscle...

...through non-homologous end joining (NHEJ) , an error-prone process that produces insertions/deletions disrupting...

...these regions, a process driven by neurons. By studying how neurons are physically connected, we can begin...these connections in the brain are (drum roll) neurons! Neurons are really cool because they can transmit ...There are two methods of neuronal tracing (Fig. 1): one to visualize neurons that send information to ... functionally dissect specific neurons within their natural environment, all while reciting their favorite...defined population of neurons. For example, say I wanted to access all the neurons that signaled from the...ligands activates both neurons at the injection site and any projection neurons retrogradely transduced... efficient retrograde access to projection neurons." Neuron 92.2 (2016): 372-382. PubMed PMID: 27720486...

.... What do microbial rhodopsins and neurons have in common? Neuronal stimulations are triggered by the ...the neuron fires, sending the electrical signal down the axon (Lodish et al., 2000). Most neurons in the...Vandenberghe, 2019). How to achieve strong opsin expression in specific neuronal cell types then? This is where... 2014). How does FLEx enable strong opsin expression in specific neuronal cells? This can be achieved ...enabling its expression under a strong promoter only in specific neuronal cells. FLEx ensures, therefore...et al. "Silencing neurons: tools, applications, and experimental constraints." Neuron 95.3 (2017): 504-...What is optogenetics? Optogenetics: Controlling neurons with light In 2005, a team from Stanford University...

...specify and assemble diverse arrays of neurons, forming the neuronal circuits that will later be refined ...individual neuronal populations.  The Yang Lab’s AAV plasmids used to express Cre under neuron-specific ...kinase II alpha (aCaMKII; excitatory neurons) and Synapsin-1 (pan-neuronal) promoters (Figure 1b), and sgRNAs...response to neuronal activity (hence, “immediate-early”) and consequently regulates neuronal physiology...between Bdnf I-overexpressing neurons and Bdnf IV-overexpressing neurons. Among the upregulated genes ...contributions of transcript isoforms to neuronal physiology. The Day Lab’s neuron-optimized lentiviral vectors can...process. However, while the neuronal marker TUJ1 is useful for visualizing neuronal differentiation by immunohistochemistry...

...CNS: neurons and astrocytes Mice No (LY6C1)   Hanlon et al., 2019 AAV-BI-28 CNS: neurons, astrocytes...astrocytes, but its neuron transduction encompasses more molecularly-defined neuronal subtypes and with ...and is highly specific for neurons, with less bias toward inhibitory neurons than AAV-PHP.eB (Fig. 4c, ...transduce 80% of dorsal root ganglia (DRG) neurons, as well as neurons located in the enteric nervous system...primate nervous systems. Neuron, 110(14), 2242-2257.e6. https://doi.org/10.1016/j.neuron.2022.05.003 Chen, X...-specific labeling. Neuron,109(9), 1449–1464.e13. https://doi.org/10.1016/j.neuron.2021.03.011 Hanlon,...cell type specificity, or retrograde transport in neurons. (b) Genetic cargo can be customized to control...

...individual neurons and in terms of their interactions with one another. In addition to the neuronal networks... (hM3Dq) into a subset of neurons within the LC of mice. When those neurons are chemogenetically activated...reward circuit, and the medial prefrontal cortex (mPFC) are involved. Neurons from the mPFC project to the...findings by controlling neurons in the mPFC with light. Activation of these neurons via the channel Channelrhodopsin...protein that activates neurons upon light stimulation. When they activated the Drd1 neurons 24 hours before ... "Optogenetic stimulation of medial prefrontal cortex Drd1 neurons produces rapid and long-lasting antidepressant...They also don’t give any clues about the types of neurons involved or whether their involvement is activating...