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pLL7.0: Venus-iLID-CAAX (from KRas4B) Citations (21)

Originally described in: Engineering an improved light-induced dimer (iLID) for controlling the localization and activity of signaling proteins.
Guntas G, Hallett RA, Zimmerman SP, Williams T, Yumerefendi H, Bear JE, Kuhlman B Proc Natl Acad Sci U S A. 2015 Jan 6;112(1):112-7. doi: 10.1073/pnas.1417910112. Epub 2014 Dec 22. PubMed Journal

Articles Citing pLL7.0: Venus-iLID-CAAX (from KRas4B)

Articles
Subcellular optogenetic activation of Cdc42 controls local and distal signaling to drive immune cell migration. O'Neill PR, Kalyanaraman V, Gautam N. Mol Biol Cell. 2016 May 1;27(9):1442-50. doi: 10.1091/mbc.E15-12-0832. Epub 2016 Mar 3. PubMed

Associated Plasmids
The Spatiotemporal Limits of Developmental Erk Signaling. Johnson HE, Goyal Y, Pannucci NL, Schupbach T, Shvartsman SY, Toettcher JE. Dev Cell. 2017 Jan 23;40(2):185-192. doi: 10.1016/j.devcel.2016.12.002. PubMed

Associated Plasmids
Multivalent Small-Molecule Pan-RAS Inhibitors. Welsch ME, Kaplan A, Chambers JM, Stokes ME, Bos PH, Zask A, Zhang Y, Sanchez-Martin M, Badgley MA, Huang CS, Tran TH, Akkiraju H, Brown LM, Nandakumar R, Cremers S, Yang WS, Tong L, Olive KP, Ferrando A, Stockwell BR. Cell. 2017 Feb 23;168(5):878-889.e29. doi: 10.1016/j.cell.2017.02.006. PubMed
Temporally precise labeling and control of neuromodulatory circuits in the mammalian brain. Lee D, Creed M, Jung K, Stefanelli T, Wendler DJ, Oh WC, Mignocchi NL, Luscher C, Kwon HB. Nat Methods. 2017 May;14(5):495-503. doi: 10.1038/nmeth.4234. Epub 2017 Apr 3. PubMed

Associated Plasmids
A calcium- and light-gated switch to induce gene expression in activated neurons. Lee D, Hyun JH, Jung K, Hannan P, Kwon HB. Nat Biotechnol. 2017 Jun 26. doi: 10.1038/nbt.3902. PubMed

Associated Plasmids
Optogenetic Control of Cell Migration. Meshik X, O'Neill PR, Gautam N. Methods Mol Biol. 2018;1749:313-324. doi: 10.1007/978-1-4939-7701-7_22. PubMed
Dynein-Dynactin-NuMA clusters generate cortical spindle-pulling forces as a multi-arm ensemble. Okumura M, Natsume T, Kanemaki MT, Kiyomitsu T. Elife. 2018 May 31;7. pii: 36559. doi: 10.7554/eLife.36559. PubMed

Associated Plasmids
Membrane Flow Drives an Adhesion-Independent Amoeboid Cell Migration Mode. O'Neill PR, Castillo-Badillo JA, Meshik X, Kalyanaraman V, Melgarejo K, Gautam N. Dev Cell. 2018 Jun 15. pii: S1534-5807(18)30422-2. doi: 10.1016/j.devcel.2018.05.029. PubMed

Associated Plasmids
Increasing spatial resolution of photoregulated GTPases through immobilized peripheral membrane proteins. Van Geel O, Hartsuiker R, Gadella TWJ. Small GTPases. 2018 Sep 5:1-10. doi: 10.1080/21541248.2018.1507411. PubMed

Associated Plasmids
The activity of Sac1 across ER-TGN contact sites requires the four-phosphate-adaptor-protein-1. Venditti R, Masone MC, Rega LR, Di Tullio G, Santoro M, Polishchuk E, Serrano IC, Olkkonen VM, Harada A, Medina DL, La Montagna R, De Matteis MA. J Cell Biol. 2019 Mar 4;218(3):783-797. doi: 10.1083/jcb.201812021. Epub 2019 Jan 18. PubMed
Self-organization of Plk4 regulates symmetry breaking in centriole duplication. Yamamoto S, Kitagawa D. Nat Commun. 2019 Apr 18;10(1):1810. doi: 10.1038/s41467-019-09847-x. PubMed
Dynamic centriolar localization of Polo and Centrobin in early mitosis primes centrosome asymmetry. Gallaud E, Ramdas Nair A, Horsley N, Monnard A, Singh P, Pham TT, Salvador Garcia D, Ferrand A, Cabernard C. PLoS Biol. 2020 Aug 6;18(8):e3000762. doi: 10.1371/journal.pbio.3000762. eCollection 2020 Aug. PubMed
Optogenetic control of small GTPases reveals RhoA mediates intracellular calcium signaling. Inaba H, Miao Q, Nakata T. J Biol Chem. 2021 Jan-Jun;296:100290. doi: 10.1016/j.jbc.2021.100290. Epub 2021 Jan 13. PubMed

Associated Plasmids
Optimized iLID Membrane Anchors for Local Optogenetic Protein Recruitment. Natwick DE, Collins SR. ACS Synth Biol. 2021 May 21;10(5):1009-1023. doi: 10.1021/acssynbio.0c00511. Epub 2021 Apr 12. PubMed

Associated Plasmids
The phosphoinositide coincidence detector Phafin2 promotes macropinocytosis by coordinating actin organisation at forming macropinosomes. Schink KO, Tan KW, Spangenberg H, Martorana D, Sneeggen M, Stevenin V, Enninga J, Campsteijn C, Raiborg C, Stenmark H. Nat Commun. 2021 Nov 12;12(1):6577. doi: 10.1038/s41467-021-26775-x. PubMed
Optogenetic relaxation of actomyosin contractility uncovers mechanistic roles of cortical tension during cytokinesis. Yamamoto K, Miura H, Ishida M, Mii Y, Kinoshita N, Takada S, Ueno N, Sawai S, Kondo Y, Aoki K. Nat Commun. 2021 Dec 8;12(1):7145. doi: 10.1038/s41467-021-27458-3. PubMed

Associated Plasmids
Persistent cell migration emerges from a coupling between protrusion dynamics and polarized trafficking. Vaidziulyte K, Mace AS, Battistella A, Beng W, Schauer K, Coppey M. Elife. 2022 Mar 18;11:e69229. doi: 10.7554/eLife.69229. PubMed
Integrin-based adhesion compartmentalizes ALK3 of the BMPRII to control cell adhesion and migration. Guevara-Garcia A, Fourel L, Bourrin-Reynard I, Sales A, Oddou C, Pezet M, Rossier O, Machillot P, Chaar L, Bouin AP, Giannone G, Destaing O, Picart C, Albiges-Rizo C. J Cell Biol. 2022 Dec 5;221(12):e202107110. doi: 10.1083/jcb.202107110. Epub 2022 Oct 7. PubMed
Microtubule retrograde flow retains neuronal polarization in a fluctuating state. Schelski M, Bradke F. Sci Adv. 2022 Nov 4;8(44):eabo2336. doi: 10.1126/sciadv.abo2336. Epub 2022 Nov 4. PubMed

Associated Plasmids
Mitochondrial control of microglial phagocytosis by the translocator protein and hexokinase 2 in Alzheimer's disease. Fairley LH, Lai KO, Wong JH, Chong WJ, Vincent AS, D'Agostino G, Wu X, Naik RR, Jayaraman A, Langley SR, Ruedl C, Barron AM. Proc Natl Acad Sci U S A. 2023 Feb 21;120(8):e2209177120. doi: 10.1073/pnas.2209177120. Epub 2023 Feb 14. PubMed
Optogenetic modulation of guanine nucleotide exchange factors of Ras superfamily proteins directly controls cell shape and movement. Pal DS, Lin Y, Zhan H, Banerjee T, Kuhn J, Providence S, Devreotes PN. Front Cell Dev Biol. 2023 Jul 10;11:1195806. doi: 10.3389/fcell.2023.1195806. eCollection 2023. PubMed

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