We narrowed to 3,836 results for: aacs

1. pSLQ7578 pHR (hU6-crPROX-EFS-PuroR-WPRE)

   Plasmid

   #214882

   Purpose

   Lentiviral vector encoding RfxCas13d targeting PROX guide array

   Depositor

   Stanley Qi

   Article

   Tieu et al Cell. 2024 Feb 29;187(5):1278-1295.e20.

   Insert

   hU6-crPROX-EFS-PuroR-WPRE
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   hU6

   Available since

   April 4, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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2. pSLQ7820 pHR (hU6-crPURI-EFS-PuroR-WPRE)

   Plasmid

   #214883

   Purpose

   Lentiviral vector encoding RfxCas13d targeting PURI guide array

   Depositor

   Stanley Qi

   Article

   Tieu et al Cell. 2024 Feb 29;187(5):1278-1295.e20.

   Insert

   hU6-crPURI-EFS-PuroR-WPRE
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   hU6

   Available since

   April 4, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

3. pSLQ7529 pHR (hU6-crLPT-EFS-PuroR-WPRE)

   Plasmid

   #214877

   Purpose

   Lentiviral vector encoding RfxCas13d targeting LPT guide array

   Depositor

   Stanley Qi

   Article

   Tieu et al Cell. 2024 Feb 29;187(5):1278-1295.e20.

   Insert

   hU6-crLPT-EFS-PuroR-WPRE
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   hU6

   Available since

   April 4, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

4. Mucolipin1 D471-472K-pHcRed C1

   Plasmid

   #62961

   Purpose

   full length human Mucolipin-1 D471/472K cloned into pHcRed1 C1

   Depositor

   Paul Luzio

   Article

   Pryor et al Traffic. 2006 Oct;7(10):1388-98.

   Insert

   Mucolipin-1 (MCOLN1 Human)
   

   Use

   Tags

   HcRed

   Expression

   Mammalian

   Mutation

   D471/472K (and two silent mutations T77 ACA inst…

   Promoter

   CMV

   Available since

   May 28, 2015

   Availability

   Academic Institutions and Nonprofits only

5. pCAG-nucGFP11-3xPax7gRNA

   Plasmid

   #224570

   Purpose

   Ubiquitous expression plasmid, CAG promoter (CMV immediate early enhancer, chicken beta actin promoter), three unique Pax7 gRNAs with ribozyme self-cleavage sites, and nuclear split GFP(11) reporter.

   Depositor

   Erica Hutchins

   Article

   Kim et al Dev Biol. 2024 Nov 30:S0012-1606(24)0026

   Insert

   GFP11-H2B
   

   Use

   CRISPR

   Tags

   Histone H2B (nuclear localization)

   Expression

   Mutation

   Codon optimized

   Promoter

   Available since

   Dec. 9, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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6. pCAG-3xGFP11-mem-3xPax7gRNA

   Plasmid

   #224571

   Purpose

   Ubiquitous expression plasmid with CAG promoter (CMV immediate early enhancer, chicken beta actin promoter), three unique Pax7 gRNAs with ribozyme self-cleavage, three membrane split GFP(11) reporter.

   Depositor

   Erica Hutchins

   Article

   Kim et al Dev Biol. 2024 Nov 30:S0012-1606(24)0026

   Insert

   3xGFP11
   

   Use

   CRISPR

   Tags

   Membrane Localization Signal

   Expression

   Mutation

   Codon optimized

   Promoter

   Available since

   Dec. 9, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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7. pAAV CAG Barcode3

   Plasmid

   #229064

   Purpose

   Expression mapping

   Depositor

   Scott Sternson

   Insert

   CAG Barcode3
   

   Use

   AAV

   Tags

   Expression

   Mutation

   Promoter

   Available since

   Dec. 3, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

8. pCAG-memRFP-3xPax7gRNA

   Plasmid

   #224569

   Purpose

   Ubiquitous expression plasmid, CAG promoter (CMV immediate early enhancer and chicken beta actin promoter), three unique Pax7 gRNAs with ribozyme self-cleavage sites, and membrane RFP reporter.

   Depositor

   Erica Hutchins

   Article

   Kim et al Dev Biol. 2024 Nov 30:S0012-1606(24)0026

   Insert

   mRFP1
   

   Use

   CRISPR

   Tags

   Membrane localization signal

   Expression

   Mutation

   Codon optimized

   Promoter

   Available since

   Dec. 9, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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9. pFlare9A-Clip2E9 Mutant

   Plasmid

   #209575

   Purpose

   minigene construct for Clip2 E9 alternative splicing, potential PTBP2 binding sites are deleted

   Depositor

   Sika Zheng

   Article

   Zhang et al Neuron. 2019 Feb 20;101(4):690-706.e10.

   Insert

   Clip2 (Clip2 Mouse)
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   ACGCGTTTCTGAATTCTTCTAACTGCCCTCAAATGCACGGTGGCATGTG…

   Promoter

   CMV

   Available since

   March 7, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

10. pCRIS

    Plasmid

    #120424

    Purpose

    This plasmid encodes the complete CRISPR/dCas9 machinery for repressing transposition of the following bacterial Insertion Sequences: IS1, IS3, IS5, and IS150.

    Depositor

    Tamás Fehér

    Article

    Nyerges et al Synth Biol (Oxf). 2019;4(1):ysz008. doi:

    Insert

    CRISPR spacers targeting IS1, IS5, IS3, IS150
    

    Use

    CRISPR and Synthetic Biology

    Tags

    Expression

    Bacterial

    Mutation

    Promoter

    constitutive

    Available since

    Jan. 17, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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11. Circular 200,100 (RAB7A)

    Plasmid

    #170118

    Purpose

    AAV vector carrying a guide RNA targeting the human RAB7A mRNA

    Depositor

    Prashant Mali

    Article

    Katrekar et al Nat Biotechnol. 2022 Feb 10. pii: 10.103

    Insert

    Circular 200,100 guide RNA (RAB7A Human)
    

    Use

    AAV

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Human U6

    Available since

    Feb. 11, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

12. Circular 200,100 (mIDUA)

    Plasmid

    #170123

    Purpose

    AAV vector carrying 2 copies of a guide RNA targeting the mouse IDUA mRNA, expressed from human and mouse U6 promoters

    Depositor

    Prashant Mali

    Article

    Katrekar et al Nat Biotechnol. 2022 Feb 10. pii: 10.103

    Insert

    Circular 200,100 guide RNA (Idua Mouse)
    

    Use

    AAV

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Human U6 and mouse U6

    Available since

    Feb. 11, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

13. Mode #2 Library (14-3-3σ)

    Pooled Library

    #111706

    Purpose

    Encodes 14-3-3σ and human phosphopeptides fused to split mCherry for Hi-P

    Depositor

    Jesse Rinehart

    Article

    Barber et al Nat Biotechnol. 2018 Aug;36(7):638-644.

    Expression

    Bacterial

    Species

    Homo sapiens

    Available since

    Dec. 1, 2022

    Availability

    Academic Institutions and Nonprofits only

14. Mode #2 Library (14-3-3β)

    Pooled Library

    #111705

    Purpose

    Encodes 14-3-3β and human phosphopeptides fused to split mCherry for Hi-P

    Depositor

    Jesse Rinehart

    Article

    Barber et al Nat Biotechnol. 2018 Aug;36(7):638-644.

    Expression

    Bacterial

    Species

    Homo sapiens

    Available since

    Dec. 1, 2022

    Availability

    Academic Institutions and Nonprofits only

15. Mode #1 Library

    Pooled Library

    #111704

    Purpose

    Encodes GST-fused human phosphopeptides

    Depositor

    Jesse Rinehart

    Article

    Barber et al Nat Biotechnol. 2018 Aug;36(7):638-644.

    Expression

    Bacterial

    Species

    Homo sapiens

    Available since

    Dec. 1, 2022

    Availability

    Academic Institutions and Nonprofits only

16. Mode #2 Library (NEDD4-2 WW2 domain)

    Pooled Library

    #111708

    Purpose

    Encodes NEDD4-2 WW2 domain and human phosphopeptides fused to split mCherry for Hi-P

    Depositor

    Jesse Rinehart

    Article

    Barber et al Nat Biotechnol. 2018 Aug;36(7):638-644.

    Expression

    Bacterial

    Species

    Homo sapiens

    Available since

    Dec. 1, 2022

    Availability

    Academic Institutions and Nonprofits only

17. Mode #2 Library (NEDD4 WW2 domain)

    Pooled Library

    #111707

    Purpose

    Encodes NEDD4 WW2 domain and human phosphopeptides fused to split mCherry for Hi-P

    Depositor

    Jesse Rinehart

    Article

    Barber et al Nat Biotechnol. 2018 Aug;36(7):638-644.

    Expression

    Bacterial

    Species

    Homo sapiens

    Available since

    Dec. 1, 2022

    Availability

    Academic Institutions and Nonprofits only

18. pAM/CBA-eGFP-miRaSyn(human)x3-WPRE-bGHpA

    Plasmid

    #194247

    Purpose

    Expresses 3 miRNAs targeting human alpha-Synuclein

    Depositor

    Michael J Fox Foundation MJFF

    Insert

    miRaSynuclein(human) (SNCA Human)
    

    Use

    AAV and RNAi

    Tags

    Expression

    Mutation

    Promoter

    CAG

    Available since

    Jan. 24, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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19. Circular 200,100 with interspersed loops (SMAD4)

    Plasmid

    #180191

    Purpose

    AAV vector carrying a guide RNA targeting the human SMAD4 mRNA

    Depositor

    Prashant Mali

    Article

    Katrekar et al Nat Biotechnol. 2022 Feb 10. pii: 10.103

    Insert

    Circular 200,100 guide RNA with interspersed loops
    

    Use

    AAV

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Human U6

    Available since

    April 4, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. pLCHKO_TK1_HPRT1_Lb_4

    Plasmid

    #155062

    Purpose

    Lentiviral plasmid for expressing U6 driven multiplexed hybrid guide (hg)RNA targeting TK1 using SpCas9 and three intergenic sites & HPRT1 using LbCas12a (CHyMErA system)

    Depositor

    Benjamin Blencowe, Jason Moffat

    Article

    Gonatopoulos-Pournatzis et al Nat Biotechnol. 2020 May;38(5):638-648.

    Insert

    (hg)RNA targeting TK1 using SpCas9 and three intergenic sites & HPRT1 using LbCas12a
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    U6

    Available since

    Aug. 13, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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