We narrowed to 8,466 results for: gnal

1. pcDNA3.1-NES-CAGEc-AF9c (Npu)

   Plasmid

   #241413

   Purpose

   Proximity-triggered Protein Trans-Splicing to generate the splice product MLL-AF9, Extended Figure 4 in Nature Chemical Biology 20.10 (2024): 1353-1360.

   Depositor

   Thomas Muir

   Article

   Lee et al bioRxiv [Preprint]. 2023 Jul 10:2023.07.

   Insert

   NES-CAGEc-AF9c (Npu) (MLLT3 Human, Synthetic)
   

   Tags

   3xFLAG and HA

   Expression

   Mammalian

   Promoter

   CMV

   Available Since

   Sept. 8, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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2. ACE2-HA-Linker-FLAG

   Plasmid

   #240602

   Purpose

   Encodes doubly tagged ACE2 protein. HA on the N-terminal added after the signal peptide (a.a 1-17) and FLAG tag at the end of the insert. A linker sequence was added after the HA tag.

   Depositor

   Zaid Abassi

   Insert

   Angiotensin-converting enzyme 2 (ACE2 Human)
   

   Tags

   FLAG tag and HA tag (after the signal peptide)

   Expression

   Mammalian

   Promoter

   CMV

   Available Since

   Aug. 11, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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3. PiggyBac-APEX-V5-NES

   Plasmid

   #229082

   Purpose

   Doxycycline-inducible expression of nuclear export signal (NES) fused to V5-tag and APEX for proximity labeling, containing BFP in the backbone

   Depositor

   Eran Hornstein

   Insert

   NES (TARDBP Human)
   

   Tags

   APEX (D11G mutation), BFP, and V5

   Expression

   Mammalian

   Promoter

   TRE3G

   Available Since

   July 2, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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4. PB-U6-CNCB

   Plasmid

   #236763

   Purpose

   A piggybac-based cloning vector containing mouse U6 promoter-driven sgRNA for spCas9 and CAG promoter-driven nuclear-localized Clover-T2A-BSR.

   Depositor

   Kazutoshi Takahashi

   Article

   Okubo et al Sci Adv. 2025 Apr 11;11(15):eadq5484. do

   Type

   Empty backbone

   Use

   Piggybac

   Expression

   Mammalian

   Promoter

   mouse U6 promoter, CAG promoter

   Available Since

   May 21, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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5. PB-TRE3G-CCRB

   Plasmid

   #236772

   Purpose

   A piggybac-based cloning vector containing TRE3G promoter followed by cloning site and CAG promoter-driven nuclear-localized Clover-P2A-rtTA-IRES-BSD.

   Depositor

   Kazutoshi Takahashi

   Article

   Okubo et al Sci Adv. 2025 Apr 11;11(15):eadq5484. do

   Type

   Empty backbone

   Use

   Piggybac

   Expression

   Mammalian

   Promoter

   TRE3G promoter, CAG promoter

   Available Since

   May 21, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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6. PB-2G-CNCB

   Plasmid

   #236764

   Purpose

   A piggybac-based cloning vector containing dual sgRNAs for spCas9 and CAG promoter-driven nuclear-localized Clover-T2A-BSR.

   Depositor

   Kazutoshi Takahashi

   Article

   Okubo et al Sci Adv. 2025 Apr 11;11(15):eadq5484. do

   Type

   Empty backbone

   Use

   Piggybac

   Expression

   Mammalian

   Promoter

   mouse U6 promoter, human U6 promoter, CAG promoter

   Available Since

   May 21, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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7. pLV hU6-VEGFR2#3 sgRNA Nestin-dCas9-KRAB-T2a-GFP

   Plasmid

   #196990

   Purpose

   Derived from pLV hU6-sgRNA Nestin-dCas9-KRAB-T2a-GFP with KDR sgRNA

   Depositor

   Elizabeth Kirby

   Article

   Dause et al Mol Neurobiol. 2025 Mar 25. doi: 10.1007

   Insert

   VEGFR2
   

   Use

   CRISPR and Lentiviral

   Available Since

   April 1, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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8. pMZ103-rbs1-m1

   Plasmid

   #204463

   Purpose

   This is a biosensor with improved specificity to 3OC12-HSL, containing LasR A127N mutation.

   Depositor

   Lauren Andrews

   Article

   Zeng et al ACS Synth Biol. 2024 Feb 16;13(2):568-58

   Inserts

   quorum sensing regulator LasR (lasR )
   eYFP
   

   Use

   Synthetic Biology

   Mutation

   LasR A127N mutation

   Promoter

   In an operon and PLas

   Available Since

   March 5, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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9. pMZ103-rbs1-m2

   Plasmid

   #204464

   Purpose

   This is a biosensor with improved specificity to 3OC12-HSL, containing LasR L128C mutation.

   Depositor

   Lauren Andrews

   Article

   Zeng et al ACS Synth Biol. 2024 Feb 16;13(2):568-58

   Inserts

   quorum sensing regulator LasR (lasR )
   eYFP
   

   Use

   Synthetic Biology

   Mutation

   LasR L128C mutation

   Promoter

   In an operon and PLas

   Available Since

   March 5, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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10. pAS3-rab-3P::AI::lite-1G::SL2::his-24::tagBFP

    Plasmid

    #232610

    Purpose

    Pan-neuronal expression of 'LITE-1' using a genomic fragment and fluorophore 'tagBFP', regulated by rab-3 promoter and unc-54 3' UTR

    Depositor

    Andrew Leifer

    Article

    Sharma et al Genetics. 2024 Jul 8;227(3):iyae077. doi

    Insert

    LITE-1 (lite-1 Nematode)
    

    Expression

    Worm

    Mutation

    N/A

    Available Since

    Feb. 20, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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11. pAS3-rab-3P::AI::gur-3G::SL2::his-24::tagBFP

    Plasmid

    #232608

    Purpose

    Pan-neuronal expression of 'GUR-3' using a genomic fragment and fluorophore 'tagBFP', regulated by rab-3 promoter and unc-54 3' UTR

    Depositor

    Andrew Leifer

    Article

    Sharma et al Genetics. 2024 Jul 8;227(3):iyae077. doi

    Insert

    GUR-3 (gur-3 Nematode)
    

    Expression

    Worm

    Mutation

    N/A

    Available Since

    Feb. 20, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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12. pAS3-rab-3P::AI::prdx-2G::SL2::his-24::tagRFP

    Plasmid

    #232609

    Purpose

    Pan-neuronal expression of 'PRDX-2' using a genomic fragment and fluorophore 'tagRFP', regulated by rab-3 promoter and unc-54 3' UTR

    Depositor

    Andrew Leifer

    Article

    Sharma et al Genetics. 2024 Jul 8;227(3):iyae077. doi

    Insert

    PRDX-2 (prdx-2 Nematode)
    

    Expression

    Worm

    Mutation

    N/A

    Available Since

    Feb. 11, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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13. CA-0140 CMVTO-Renin-ECL-CD4-tevs-RXR6.2

    Plasmid

    #231199

    Purpose

    ER-retained renin

    Depositor

    Xiaojing Gao

    Article

    Aldrete et al Nat Chem Biol. 2025 Jan 15. doi: 10.1038

    Insert

    Renin-ECL-CD4-tevs-RXR6.2 (REN Human)
    

    Expression

    Mammalian

    Available Since

    Jan. 27, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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14. CA-0151 CMVTO-Renin(H2M)-ECL

    Plasmid

    #231201

    Purpose

    Membrane-bound human-to-mouse (H2M) renin

    Depositor

    Xiaojing Gao

    Article

    Aldrete et al Nat Chem Biol. 2025 Jan 15. doi: 10.1038

    Insert

    Renin(H2M)-ECL (REN Human)
    

    Expression

    Mammalian

    Mutation

    L147I, R148H, I203V, L290V

    Available Since

    Jan. 24, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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15. CMVTO-hIL2 (AV)

    Plasmid

    #231226

    Purpose

    hIL2

    Depositor

    Xiaojing Gao

    Article

    Aldrete et al Nat Chem Biol. 2025 Jan 15. doi: 10.1038

    Insert

    hIL2 (IL2 Human)
    

    Expression

    Mammalian

    Available Since

    Jan. 24, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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16. pIRES2_hMela(CT+IL3 mGluR6)

    Plasmid

    #191343

    Purpose

    Optogenetic tool

    Depositor

    Sonja Kleinlogel

    Article

    Kralik et al Commun Biol. 2022 Oct 20;5(1):1116. doi:

    Insert

    hMela(CT+IL3 mGluR6)
    

    Tags

    IRES_Turbo

    Expression

    Mammalian

    Available Since

    Dec. 12, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. pIRES2_hMela(CT mGluR6)

    Plasmid

    #191344

    Purpose

    Optogenetic tool

    Depositor

    Sonja Kleinlogel

    Article

    Kralik et al Commun Biol. 2022 Oct 20;5(1):1116. doi:

    Insert

    hMela(CTmGluR6)
    

    Tags

    IRES_Turbo

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    Dec. 12, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. p104Tol2-tp1:Cas9-t2A-GFP, 4xU6:sgRNA

    Plasmid

    #227773

    Purpose

    Expression of tp1 (Notch) dependent Cas9-GFP and U6-driven 4 sgRNAs in zebrafish

    Depositor

    Bushra Raj

    Article

    Siniscalco et al Development. 2024 Nov 22:dev.203102. doi

    Inserts

    Cas9-t2A-GFP
    4xU6:sgRNA
    

    Use

    CRISPR

    Promoter

    U6 and tp1

    Available Since

    Dec. 10, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. p8270 LentiCRISPR v2 hygro sgSIGIRR-3

    Plasmid

    #193979

    Purpose

    Expression of spCas9 and sgRNA targeting SIGIRR

    Depositor

    Elizabeth White

    Article

    Castagnino et al J Virol. 2022 Nov 7:e0132622. doi: 10.11

    Insert

    spCas9 and sgRNA targeting SIGIRR (SIGIRR Human)
    

    Use

    Lentiviral

    Available Since

    Nov. 8, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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20. pCI-SMN2-inclusion-GLuc

    Plasmid

    #218671

    Purpose

    Alternative splicing signaling: signal increased with Ex7 inclusion increasing

    Depositor

    Jingxin Wang

    Article

    Tang et al Chembiochem. 2022 May 4;23(9):e202200012

    Insert

    SMN2 (SMN2 )
    

    Expression

    Mammalian

    Available Since

    Sept. 9, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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