We narrowed to 7,695 results for: ALP

1. pOET3-6xHis-hSMSr-ΔSAMD

   Plasmid

   #236225

   Purpose

   Express N-terminal His-tagged human SMSr (SAMD8)-sterile alpha motif domain deletion mutant protein in insect cells

   Depositor

   Chiaki Murakami

   Article

   Murakami et al J Biol Chem. 2021 Jan-Jun;296:100454. do

   Insert

   SAMD8 (SAMD8 Human)
   

   Tags

   Hexa histidine tag (6xHis-tag) and enterokinase s…

   Expression

   Insect

   Mutation

   sterile alpha motif domain at N-terminal (1-231 b…

   Available Since

   May 1, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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2. AAV-U6/TO-shEsr1-CMV-TetR-eGFP

   Plasmid

   #233298

   Purpose

   DOX-inducible U6 driven shRNA against mouse Esr1

   Depositor

   Dayu Lin

   Article

   Golden et al bioRxiv [Preprint]. 2024 Sep 25:2023.12.

   Insert

   Esr1 shRNA (Esr1 Mouse)
   

   Use

   AAV

   Expression

   Mammalian

   Promoter

   U6

   Available Since

   March 24, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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3. pLenti-multi-CRISPR-sgRipk3_#2-puro

   Plasmid

   #231982

   Purpose

   Knockout mouse Ripk3

   Depositor

   Brian Ruffell

   Article

   Hanggi et al Cancer Cell. 2024 Nov 13:S1535-6108(24)0

   Insert

   sgRNA with Cas9 with puromycin resistance (Ripk3 Mouse)
   

   Use

   CRISPR and Lentiviral

   Available Since

   Feb. 7, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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4. pLenti-multi-CRISPR-sgRipk3_#1-puro

   Plasmid

   #231981

   Purpose

   Knockout mouse Ripk3

   Depositor

   Brian Ruffell

   Article

   Hanggi et al Cancer Cell. 2024 Nov 13:S1535-6108(24)0

   Insert

   sgRNA with Cas9 with puromycin resistance (Ripk3 Mouse)
   

   Use

   CRISPR and Lentiviral

   Available Since

   Feb. 7, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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5. pLenti-multi-CRISPR-sgMlkl_#2-puro

   Plasmid

   #231980

   Purpose

   Knockout mouse Mlkl

   Depositor

   Brian Ruffell

   Article

   Hanggi et al Cancer Cell. 2024 Nov 13:S1535-6108(24)0

   Insert

   sgRNA with Cas9 with puromycin resistance (Mlkl Mouse)
   

   Use

   CRISPR and Lentiviral

   Available Since

   Feb. 7, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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6. pLenti-multi-CRISPR-sgMlkl_#1-puro

   Plasmid

   #231979

   Purpose

   Knockout mouse Mlkl

   Depositor

   Brian Ruffell

   Article

   Hanggi et al Cancer Cell. 2024 Nov 13:S1535-6108(24)0

   Insert

   sgRNA with Cas9 with puromycin resistance (Mlkl Mouse)
   

   Use

   CRISPR and Lentiviral

   Available Since

   Feb. 7, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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7. pLVX MLKL(1-180)-2A-mCherry-puro

   Plasmid

   #231976

   Purpose

   Tet inducible expression of DmrB-Mlkl with mCherry to induce MLKL 1-180 necroptosis

   Depositor

   Brian Ruffell

   Article

   Hanggi et al Cancer Cell. 2024 Nov 13:S1535-6108(24)0

   Insert

   MLKL 1-180 construct with bi-cistronic mCherry (Mlkl Mouse)
   

   Use

   Lentiviral

   Available Since

   Feb. 7, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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8. pLVX MLKL(S345D)-2A-mCherry-puro

   Plasmid

   #231975

   Purpose

   Tet inducible expression of DmrB-Mlkl with mCherry to induce phosphomimetic MLKL S345D necroptosis

   Depositor

   Brian Ruffell

   Article

   Hanggi et al Cancer Cell. 2024 Nov 13:S1535-6108(24)0

   Insert

   MLKL S345D construct with bi-cistronic mCherry (Mlkl Mouse)
   

   Use

   Lentiviral

   Mutation

   MLKL S345D

   Available Since

   Feb. 7, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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9. 3xFLAG-DGKδ2

   Plasmid

   #226506

   Purpose

   Express N-terminal three tandem FLAG epitope tags, followed by an enterokinase cleavage site and human DGKD gene

   Depositor

   Fumio Sakane, Chiaki Murakami

   Article

   Murakami et al J Biol Chem. 2020 Mar 6;295(10):2932-294

   Insert

   DGKD (DGKD Human)
   

   Tags

   Three tandem FLAG epitope tag and enterokinase cl…

   Expression

   Mammalian

   Promoter

   CMV

   Available Since

   Jan. 6, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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10. HA-MAP4K4-10A

    Plasmid

    #229403

    Purpose

    Lentiviral or overpexression of cDNA

    Depositor

    Christopher Vakoc

    Article

    Klingbeil et al Cancer Discov. 2024 Jul 26. doi: 10.1158

    Insert

    MAP4K4 (MAP4K4 Human)
    

    Use

    Lentiviral

    Tags

    HA

    Expression

    Mammalian

    Mutation

    MARK2 phosphosites (S523,S536,S547,S643,T684,S726…

    Promoter

    EFS

    Available Since

    Dec. 12, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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11. HA-MAP4K4-10D

    Plasmid

    #229404

    Purpose

    Lentiviral or overpexression of cDNA

    Depositor

    Christopher Vakoc

    Article

    Klingbeil et al Cancer Discov. 2024 Jul 26. doi: 10.1158

    Insert

    MAP4K4 (MAP4K4 Human)
    

    Use

    Lentiviral

    Tags

    HA

    Expression

    Mammalian

    Mutation

    MARK2 phosphosites (S523,S536,S547,S643,T684,S726…

    Promoter

    EFS

    Available Since

    Dec. 12, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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12. pCA528 IST1 L328D (316-366)(C-Cys)

    Plasmid

    #193035

    Purpose

    Bacterial expression plasmid for IST1 (316-366) with C-terminal Cysteine for fluorescence polarization binding assays. Contains L328D mutation that diminishes binding to MIT domains.

    Depositor

    Wesley Sundquist

    Article

    Paine et al Elife. 2023 Sep 29;12:e84515. doi: 10.75

    Insert

    IST1 (IST1 Human)
    

    Tags

    6xHis-Sumo

    Expression

    Bacterial

    Mutation

    L328D, Residues 316-366, Non-native C-terminal Cy…

    Promoter

    T7

    Available Since

    Dec. 9, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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13. pCA528 IST1 L355A (316-366)(C-Cys)

    Plasmid

    #193036

    Purpose

    Bacterial expression plasmid for IST1 (316-366) with C-terminal Cysteine for fluorescence polarization binding assays. Contains L355A mutation that diminishes binding to MIT domains.

    Depositor

    Wesley Sundquist

    Article

    Paine et al Elife. 2023 Sep 29;12:e84515. doi: 10.75

    Insert

    IST1 (IST1 Human)
    

    Tags

    6xHis-Sumo

    Expression

    Bacterial

    Mutation

    L355A, Residues 316-366, Non-native C-terminal Cy…

    Promoter

    T7

    Available Since

    Dec. 9, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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14. pSuper Retro GFP DGK zeta mouse

    Plasmid

    #224577

    Purpose

    Negative Control for downregulation of the expression of human DGK zeta in human cells

    Depositor

    Isabel Mérida

    Article

    Torres-Ayuso et al Oncotarget. 2014 Oct 30;5(20):9710-26. d

    Insert

    sh RNAi Diacylglycerol kinase zeta mouse (Dgkz Mouse)
    

    Use

    RNAi and Retroviral

    Promoter

    H1

    Available Since

    Sept. 19, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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15. pAAV-U6-sgPet-1-hSyn-mCherry-KASH

    Plasmid

    #223227

    Purpose

    guideRNA targeting the mouse Pet-1 (Fev)

    Depositor

    Kyungjin Kim

    Article

    Park et al Commun Biol. 2024 Aug 15;7(1):998. doi:

    Insert

    Fev (Fev Mouse)
    

    Use

    AAV, CRISPR, and Mouse Targeting

    Tags

    mCherry

    Expression

    Mammalian

    Promoter

    U6

    Available Since

    Sept. 11, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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16. mTph2p(330bp)-mut1-Luc

    Plasmid

    #223664

    Purpose

    Firefly-luciferase reporter expression driven by proximal 330-bp of mouse Tph2 promoter point mutation at RRE site 1

    Depositor

    Kyungjin Kim

    Article

    Park et al Commun Biol. 2024 Aug 15;7(1):998. doi:

    Insert

    mTph2 promoter (Tph2 Mouse)
    

    Use

    Luciferase

    Tags

    Firefly luciferase

    Expression

    Mammalian

    Promoter

    mTph2 promoter

    Available Since

    Sept. 11, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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17. mTph2p(330bp)-mut2-Luc

    Plasmid

    #223665

    Purpose

    Firefly-luciferase reporter expression driven by proximal 330-bp of mouse Tph2 promoter point mutation at RRE site 2

    Depositor

    Kyungjin Kim

    Article

    Park et al Commun Biol. 2024 Aug 15;7(1):998. doi:

    Insert

    mTph2 promoter (Tph2 Mouse)
    

    Use

    Luciferase

    Tags

    Firefly luciferase

    Expression

    Mammalian

    Promoter

    mTph2 promoter

    Available Since

    Sept. 11, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. mTph2p(330bp)-mut3-Luc

    Plasmid

    #223666

    Purpose

    Firefly-luciferase reporter expression driven by proximal 330-bp of mouse Tph2 promoter point mutation at PRE site 3

    Depositor

    Kyungjin Kim

    Article

    Park et al Commun Biol. 2024 Aug 15;7(1):998. doi:

    Insert

    mTph2 promoter (Tph2 Mouse)
    

    Use

    Luciferase

    Tags

    Firefly luciferase

    Expression

    Mammalian

    Promoter

    mTph2 promoter

    Available Since

    Sept. 11, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. mTph2p(330bp)-mut4-Luc

    Plasmid

    #223667

    Purpose

    Firefly-luciferase reporter expression driven by proximal 330-bp of mouse Tph2 promoter point mutation at PRE site 4

    Depositor

    Kyungjin Kim

    Article

    Park et al Commun Biol. 2024 Aug 15;7(1):998. doi:

    Insert

    mTph2 promoter (Tph2 Mouse)
    

    Use

    Luciferase

    Tags

    Firefly luciferase

    Expression

    Mammalian

    Promoter

    mTph2 promoter

    Available Since

    Sept. 11, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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20. pKLV2-U6gRNA5(RUNX1(13))-PGKpuro2ABFP-W

    Plasmid

    #200501

    Purpose

    Lentiviral vector expressing gRNA targeting human RUNX1

    Depositor

    Kosuke Yusa

    Article

    Aoki et al Blood. 2023 Nov 3:blood.2023020857. doi:

    Insert

    RUNX1(13) (RUNX1 Human)
    

    Use

    Lentiviral

    Available Since

    Jan. 17, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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