We narrowed to 1,391 results for: lentiviral backbone

1. MTK Lentivirus Single Cassette Destination Vector (pAN2414)

   Plasmid

   #194220

   Purpose

   Backbone for constructing single casette expression plasmids using the Mammalian Tookit

   Depositor

   Hana El-Samad

   Article

   Weinberg et al bioRxiv 2021.04.20.440678

   Type

   Empty backbone

   Use

   Lentiviral

   Available Since

   Sept. 10, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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2. TDP-REGv2(mScarlet-FLAG)#7 in pTwist-CMV backbone

   Plasmid

   #216152

   Purpose

   Expresses mScarlet in cells with TDP-43 loss-of-function. This plasmid has one of the best dynamic ranges of those tested (~100-fold) in SK-N-BE2 cells. It uses a cryptic exon. [Code 'A11'] Note: It is not recommended to produce lentiviruses containing TDP-REG sequences – see Depositor Comments

   Depositor

   Pietro Fratta

   Article

   Wilkins et al Science. 2024 Oct 4;386(6717):61-69. doi

   Insert

   mScarlet with cryptic exon and C-terminal FLAG
   

   Expression

   Mammalian

   Promoter

   CMV

   Available Since

   July 1, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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3. TDP-REGv2(mScarlet-FLAG)#9 in pTwist-CMV backbone

   Plasmid

   #216153

   Purpose

   Expresses mScarlet in cells with TDP-43 loss-of-function. Has one of the best dynamic ranges of those tested (~100-fold) in SK-N-BE2 cells (brighter than #7). It uses a single intron. [Code 'B11']. Note: It is not recommended to produce lentiviruses containing TDP-REG sequences – see Depositor Comments

   Depositor

   Pietro Fratta

   Article

   Wilkins et al Science. 2024 Oct 4;386(6717):61-69. doi

   Insert

   mScarlet with cryptic splice site and C-terminal FLAG tag
   

   Expression

   Mammalian

   Available Since

   July 1, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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4. TDP-REGv2(mScarlet-FLAG)#10 in pTwist-CMV backbone

   Plasmid

   #216154

   Purpose

   Expresses mScarlet in cells with TDP-43 loss-of-function. Leaky but very sensitive to mild TDP-43 loss of function. It uses a cryptic exon. [Code 'B5'] Note: It is not recommended to produce lentiviruses containing TDP-REG sequences – see Depositor Comments

   Depositor

   Pietro Fratta

   Article

   Wilkins et al Science. 2024 Oct 4;386(6717):61-69. doi

   Insert

   mScarlet with cryptic exon and C-terminal FLAG
   

   Expression

   Mammalian

   Available Since

   July 1, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

5. TDP-REGv2(mScarlet-FLAG)#11 in pTwist-CMV backbone

   Plasmid

   #216155

   Purpose

   Expresses mScarlet in cells with TDP-43 loss-of-function. Very bright and decent dynamic range (>10-fold), slightly leaky. It uses a single intron. [Code 'B12']. Note: It is not recommended to produce lentiviruses containing TDP-REG sequences – see Depositor Comments

   Depositor

   Pietro Fratta

   Article

   Wilkins et al Science. 2024 Oct 4;386(6717):61-69. doi

   Insert

   mScarlet with cryptic splice site and C-terminal FLAG tag
   

   Expression

   Mammalian

   Available Since

   July 1, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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6. Human CRISPRi sgRNA library Dolcetto in backbone XPR_050, Set A

   Pooled Library

   #92385

   Purpose

   Crispri

   Depositor

   John Doench, David Root

   Article

   Sanson et al Nat Commun. 2018 Dec 21;9(1):5416. doi:

   Has Service

   Lentiviral Prep

   Use

   Lentiviral

   Available Since

   July 13, 2018

   Availability

   Academic Institutions and Nonprofits only

7. Human CRISPRa sgRNA library Calabrese in backbone XPR_502 (P65 HSF), Set A

   Pooled Library

   #92379

   Purpose

   CRISPRa

   Depositor

   John Doench, David Root

   Article

   Sanson et al Nat Commun. 2018 Dec 21;9(1):5416. doi:

   Has Service

   Lentiviral Prep

   Use

   Lentiviral

   Available Since

   Aug. 3, 2017

   Availability

   Academic Institutions and Nonprofits only

8. Human sgRNA library Gattinara in pRDA_118 backbone

   Pooled Library

   #136986

   Purpose

   Expresses sgRNAs targeting human genes

   Depositor

   John Doench

   Article

   DeWeirdt et al Nat Commun. 2020 Feb 6;11(1):752. doi: 1

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available Since

   Feb. 24, 2020

   Availability

   Academic Institutions and Nonprofits only

9. Mouse sgRNA library Gouda in pRDA_118 backbone

   Pooled Library

   #136987

   Purpose

   Expresses sgRNAs targeting mouse genes

   Depositor

   John Doench

   Article

   DeWeirdt et al Nat Commun. 2020 Feb 6;11(1):752. doi: 1

   Expression

   Mammalian

   Species

   Mus musculus

   Use

   CRISPR and Lentiviral

   Available Since

   Feb. 24, 2020

   Availability

   Academic Institutions and Nonprofits only

10. Human CRISPRi sgRNA library Dolcetto in backbone XPR_050, Set B

    Pooled Library

    #92386

    Purpose

    Crispri

    Depositor

    John Doench, David Root

    Article

    Sanson et al Nat Commun. 2018 Dec 21;9(1):5416. doi:

    Use

    Lentiviral

    Available Since

    July 13, 2018

    Availability

    Academic Institutions and Nonprofits only

11. Mouse CRISPRi sgRNA library Dolomiti in backbone XPR_050, Set A

    Pooled Library

    #104090

    Purpose

    Crispri

    Depositor

    John Doench, David Root

    Article

    Sanson et al Nat Commun. 2018 Dec 21;9(1):5416. doi:

    Use

    Lentiviral

    Available Since

    July 13, 2018

    Availability

    Academic Institutions and Nonprofits only

12. Mouse CRISPRi sgRNA library Dolomiti in backbone XPR_050, Set B

    Pooled Library

    #104091

    Purpose

    Crispri

    Depositor

    John Doench, David Root

    Article

    Sanson et al Nat Commun. 2018 Dec 21;9(1):5416. doi:

    Use

    Lentiviral

    Available Since

    July 13, 2018

    Availability

    Academic Institutions and Nonprofits only

13. Human CRISPRa sgRNA library Calabrese in backbone XPR_502 (P65 HSF), Set B

    Pooled Library

    #92380

    Purpose

    CRISPRa

    Depositor

    John Doench, David Root

    Article

    Sanson et al Nat Commun. 2018 Dec 21;9(1):5416. doi:

    Use

    Lentiviral

    Available Since

    Aug. 3, 2017

    Availability

    Academic Institutions and Nonprofits only

14. Human Brunello kinome pooled library, guides 1-4 in lentiCRISPRv2 backbone

    Pooled Library

    #75314

    Purpose

    Human sgRNA library in backbone lentiCRISPRv2 targeting 763 kinase genes and containing 3,052 unique sgRNAs along with 100 non-targeting controls

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available Since

    June 27, 2016

    Availability

    Academic Institutions and Nonprofits only

15. Human Brunello kinome pooled library, guides 5-8 in lentiCRISPRv2 backbone

    Pooled Library

    #75315

    Purpose

    Human sgRNA library in backbone lentiCRISPRv2 targeting 763 kinase genes and containing 3,052 unique sgRNAs along with 100 non-targeting controls

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available Since

    June 27, 2016

    Availability

    Academic Institutions and Nonprofits only

16. Mouse CRISPRa sgRNA library Caprano in backbone XPR_502 (P65 HSF), Set A

    Pooled Library

    #92383

    Purpose

    CRISPRa

    Depositor

    John Doench, David Root

    Article

    Sanson et al Nat Commun. 2018 Dec 21;9(1):5416. doi:

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available Since

    July 13, 2018

    Availability

    Academic Institutions and Nonprofits only

17. Mouse CRISPRa sgRNA library Caprano in backbone XPR_502 (P65 HSF), Set B

    Pooled Library

    #92384

    Purpose

    CRISPRa

    Depositor

    John Doench, David Root

    Article

    Sanson et al Nat Commun. 2018 Dec 21;9(1):5416. doi:

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available Since

    July 13, 2018

    Availability

    Academic Institutions and Nonprofits only

18. Human Brunello kinome pooled library, guides 1-4 in lentiGuide-Puro backbone

    Pooled Library

    #75312

    Purpose

    Human sgRNA library in backbone lentiGuide-Puro targeting 763 kinase genes and containing 3,052 unique sgRNAs along with 100 non-targeting controls

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available Since

    June 27, 2016

    Availability

    Academic Institutions and Nonprofits only

19. Human Brunello kinome pooled library, guides 5-8 in lentiGuide-Puro backbone

    Pooled Library

    #75313

    Purpose

    Human sgRNA library in backbone lentiGuide-Puro targeting 763 kinase genes and containing 3,052 unique sgRNAs along with 100 non-targeting controls

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available Since

    June 27, 2016

    Availability

    Academic Institutions and Nonprofits only

20. pAG Lenti CMV Empty Puro

    Plasmid

    #236083

    Purpose

    Empty lentiviral backbone

    Depositor

    Melina Fan

    Type

    Empty backbone

    Use

    Lentiviral

    Promoter

    CMV

    Available Since

    April 25, 2025

    Availability

    Industry, Academic Institutions, and Nonprofits

    

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