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We narrowed to 9,355 results for: APP

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Showing: 7801 - 7850 of 9355 results

  3. pRCA805 - pBA904 Puro-T2A-GFP KLF4 g1 CRISPRa guide (pRCA360 backbone) 668

    Plasmid
    #238174
    Purpose
    Lentiviral CRISPR guide vector expressing a KLF4 sgRNA with cs1 incorporated in the loop of the sgRNA constant region for 10X Direct Capture
    Depositor
    Thomas Norman
    Article
    Southard et al Nat Genet. 2025 Aug 6. doi: 10.1038/s415
    Insert
    KLF4 sgRNA CRISPRa (KLF4 Synthetic, Human)
    Use
    CRISPR and Lentiviral
    Tags
    GFP
    Available Since
    June 3, 2025
    Availability
    Academic Institutions and Nonprofits only
    238174-plasmid-map-sequence-id-474465

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  4. pRCA803 - pBA904 Puro-T2A-GFP KLF5 g1 CRISPRa guide (pRCA360 backbone) 666

    Plasmid
    #238172
    Purpose
    Lentiviral CRISPR guide vector expressing a KLF5 sgRNA with cs1 incorporated in the loop of the sgRNA constant region for 10X Direct Capture
    Depositor
    Thomas Norman
    Article
    Southard et al Nat Genet. 2025 Aug 6. doi: 10.1038/s415
    Insert
    KLF5 sgRNA CRISPRa (KLF5 Synthetic, Human)
    Use
    CRISPR and Lentiviral
    Tags
    GFP
    Available Since
    June 3, 2025
    Availability
    Academic Institutions and Nonprofits only
    238172-plasmid-map-sequence-id-474457

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  5. pRCA804 - pBA904 Puro-T2A-GFP KLF5 g2 CRISPRa guide (pRCA360 backbone) 665

    Plasmid
    #238173
    Purpose
    Lentiviral CRISPR guide vector expressing a KLF5 sgRNA with cs1 incorporated in the loop of the sgRNA constant region for 10X Direct Capture
    Depositor
    Thomas Norman
    Article
    Southard et al Nat Genet. 2025 Aug 6. doi: 10.1038/s415
    Insert
    KLF5 sgRNA CRISPRa (KLF5 Synthetic, Human)
    Use
    CRISPR and Lentiviral
    Tags
    GFP
    Available Since
    June 3, 2025
    Availability
    Academic Institutions and Nonprofits only
    238173-plasmid-map-sequence-id-474456

    Enlarge

  6. pRCA895 - pBA904 Puro-T2A-BFP KLF4 g1 CRISPRa guide guide (pRCA594 backbone) 668

    Plasmid
    #238187
    Purpose
    Lentiviral CRISPR guide vector expressing a KLF4 sgRNA with cs1 incorporated in the loop of the sgRNA constant region for 10X Direct Capture
    Depositor
    Thomas Norman
    Article
    Southard et al Nat Genet. 2025 Aug 6. doi: 10.1038/s415
    Insert
    KLF4 sgRNA CRISPRa (KLF4 Synthetic, Human)
    Use
    CRISPR and Lentiviral
    Tags
    mTagBFP2
    Available Since
    June 3, 2025
    Availability
    Academic Institutions and Nonprofits only
    238187-plasmid-map-sequence-id-474450

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  7. A1-LCD allW D262V

    Plasmid
    #234616
    Purpose
    Bacterial expression of N-terminally 6His tagged hnRNPA1 LCD (186-320) D262V with all aromatic amino acids mutated to W keeping the hexapeptide fibril core (SYNDFG) intact.
    Depositor
    Tanja Mittag
    Article
    Das et al bioRxiv [Preprint]. 2024 Mar 3:2024.02.2
    Insert
    hnRNPA1_LCD_allW D262V (HNRNPA1 Human)
    Tags
    6xHis-TEV
    Expression
    Bacterial
    Mutation
    C-terminal domain (186-320) bearing familial ALS …
    Promoter
    T7
    Available Since
    April 15, 2025
    Availability
    Academic Institutions and Nonprofits only
    234616-plasmid-map-sequence-id-469043

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  8. A1-LCD allW D262N

    Plasmid
    #234615
    Purpose
    Bacterial expression of N-terminally 6His tagged hnRNPA1 LCD (186-320) D262N with all aromatic amino acids mutated to W keeping the hexapeptide fibril core (SYNDFG) intact.
    Depositor
    Tanja Mittag
    Article
    Das et al bioRxiv [Preprint]. 2024 Mar 3:2024.02.2
    Insert
    hnRNPA1_LCD_allW D262N (HNRNPA1 Human)
    Tags
    6xHis-TEV
    Expression
    Bacterial
    Mutation
    C-terminal domain (186-320) bearing familial ALS …
    Promoter
    T7
    Available Since
    April 15, 2025
    Availability
    Academic Institutions and Nonprofits only
    234615-plasmid-map-sequence-id-469028

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  31. pMEXneo-TrkC-Δ6

    Plasmid
    #190204
    Purpose
    To express the human TrkC that has in the extracellular domain only the second IgG like domain. Still binds NT-3.
    Depositor
    Pantelis Tsoulfas
    Article
    Urfer et al J Biol Chem. 1998 Mar 6;273(10):5829-40.
    Insert
    TrkC (NTRK3 Human)
    Expression
    Mammalian
    Mutation
    The extracellualr domain conatins only the signal…
    Promoter
    Moloney mouse sarcoma virus right LTR
    Available Since
    Sept. 30, 2022
    Availability
    Academic Institutions and Nonprofits only
    190204-plasmid-map-sequence-id-373714

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  35. A1-LCD-2R-2K+3D

    Plasmid
    #178680
    Purpose
    Bacterial expression of N-terminally 6His tagged A1-LCD with two Arg residues removed, two Lys removed, three Asp added (LCD: low-complexity domain, aa 186-320)
    Depositor
    Tanja Mittag
    Article
    Bremer et al Nat Chem. 2022 Feb;14(2):196-207. doi: 1
    Insert
    A1-LCD-2R+2K+3D (HNRNPA1 Human)
    Tags
    6xHis
    Expression
    Bacterial
    Mutation
    two Arg residues removed, two Lys added, three As…
    Available Since
    March 17, 2022
    Availability
    Academic Institutions and Nonprofits only
    178680-plasmid-map-sequence-id-356258

    Enlarge

  36. A1-LCD-9F+3Y

    Plasmid
    #178663
    Purpose
    Bacterial expression of N-terminally 6His tagged A1-LCD with nine Phe residues removed, three Tyr added (LCD: low-complexity domain, aa 186-320)
    Depositor
    Tanja Mittag
    Article
    Bremer et al Nat Chem. 2022 Feb;14(2):196-207. doi: 1
    Insert
    A1-LCD-9F+3Y (HNRNPA1 Human)
    Tags
    6xHis
    Expression
    Bacterial
    Mutation
    nine Phe residues removed, three Tyr added
    Available Since
    March 10, 2022
    Availability
    Academic Institutions and Nonprofits only
    178663-plasmid-map-sequence-id-356435

    Enlarge

  37. A1-LCD-14N+14Q

    Plasmid
    #178692
    Purpose
    Bacterial expression of N-terminally 6His tagged A1-LCD with fourteen Gln residues replaced with Asn (LCD: low-complexity domain, aa 186-320)
    Depositor
    Tanja Mittag
    Article
    Bremer et al Nat Chem. 2022 Feb;14(2):196-207. doi: 1
    Insert
    A1-LCD-14N+14Q (HNRNPA1 Human)
    Tags
    6xHis
    Expression
    Bacterial
    Mutation
    fourteen Gln residues replaced with Asn
    Available Since
    March 10, 2022
    Availability
    Academic Institutions and Nonprofits only
    178692-plasmid-map-sequence-id-356415

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  39. A1-LCD+7K+12D

    Plasmid
    #178679
    Purpose
    Bacterial expression of N-terminally 6His tagged A1-LCD with seven Lys residues added, twelve Glu residues added (LCD: low-complexity domain, aa 186-320)
    Depositor
    Tanja Mittag
    Article
    Bremer et al Nat Chem. 2022 Feb;14(2):196-207. doi: 1
    Insert
    A1-LCD+7K+12D (HNRNPA1 Human)
    Tags
    6xHis
    Expression
    Bacterial
    Mutation
    seven Lys residues added, twelve Glu residues add…
    Available Since
    March 10, 2022
    Availability
    Academic Institutions and Nonprofits only
    178679-plasmid-map-sequence-id-356398

    Enlarge

  40. A1-LCD-30G+30S

    Plasmid
    #178684
    Purpose
    Bacterial expression of N-terminally 6His tagged A1-LCD with thirty Gly residues replaced with Ser (LCD: low-complexity domain, aa 186-320)
    Depositor
    Tanja Mittag
    Article
    Bremer et al Nat Chem. 2022 Feb;14(2):196-207. doi: 1
    Insert
    A1-LCD-30G+30S (HNRNPA1 Human)
    Tags
    6xHis
    Expression
    Bacterial
    Mutation
    thirty Gly residues replaced with Ser
    Available Since
    March 9, 2022
    Availability
    Academic Institutions and Nonprofits only
    178684-plasmid-map-sequence-id-356310

    Enlarge

  41. A1-LCD+23G-23S

    Plasmid
    #178685
    Purpose
    Bacterial expression of N-terminally 6His tagged A1-LCD with twenty-three Ser residues replaced with Gly (LCD: low-complexity domain, aa 186-320)
    Depositor
    Tanja Mittag
    Article
    Bremer et al Nat Chem. 2022 Feb;14(2):196-207. doi: 1
    Insert
    A1-LCD+23G-23S (HNRNPA1 Human)
    Tags
    6xHis
    Expression
    Bacterial
    Mutation
    twenty-three Ser residues replaced with Gly
    Available Since
    March 9, 2022
    Availability
    Academic Institutions and Nonprofits only
    178685-plasmid-map-sequence-id-356307

    Enlarge

  42. A1-LCD-4R-2K+5D

    Plasmid
    #178681
    Purpose
    Bacterial expression of N-terminally 6His tagged A1-LCD with four Arg residues removed, two Lys removed, five Asp added (LCD: low-complexity domain, aa 186-320)
    Depositor
    Tanja Mittag
    Article
    Bremer et al Nat Chem. 2022 Feb;14(2):196-207. doi: 1
    Insert
    A1-LCD-4R+2K+5D (HNRNPA1 Human)
    Tags
    6xHis
    Expression
    Bacterial
    Mutation
    four Arg residues removed, two Lys added, five As…
    Available Since
    March 9, 2022
    Availability
    Academic Institutions and Nonprofits only
    178681-plasmid-map-sequence-id-356295

    Enlarge

  43. A1-LCD-9F+6Y

    Plasmid
    #178661
    Purpose
    Bacterial expression of N-terminally 6His tagged A1-LCD with nine Phe residues removed, six Tyr added (LCD: low-complexity domain, aa 186-320)
    Depositor
    Tanja Mittag
    Article
    Bremer et al Nat Chem. 2022 Feb;14(2):196-207. doi: 1
    Insert
    A1-LCD-9F+6Y (HNRNPA1 Human)
    Tags
    6xHis
    Expression
    Bacterial
    Mutation
    nine Phe residues removed, six Tyr added
    Available Since
    March 9, 2022
    Availability
    Academic Institutions and Nonprofits only
    178661-plasmid-map-sequence-id-356293

    Enlarge

  44. A1-LCD-8F+4Y

    Plasmid
    #178662
    Purpose
    Bacterial expression of N-terminally 6His tagged A1-LCD with eight Phe residues removed, four Tyr added (LCD: low-complexity domain, aa 186-320)
    Depositor
    Tanja Mittag
    Article
    Bremer et al Nat Chem. 2022 Feb;14(2):196-207. doi: 1
    Insert
    A1-LCD-8F+4Y (HNRNPA1 Human)
    Tags
    6xHis
    Expression
    Bacterial
    Mutation
    eight Phe residues removed, four Tyr added
    Available Since
    March 8, 2022
    Availability
    Academic Institutions and Nonprofits only
    178662-plasmid-map-sequence-id-356201

    Enlarge

  45. A1-LCD+7R+10D

    Plasmid
    #178677
    Purpose
    Bacterial expression of N-terminally 6His tagged A1-LCD with seven Arg residues added, ten Glu residues added (LCD: low-complexity domain, aa 186-320)
    Depositor
    Tanja Mittag
    Article
    Bremer et al Nat Chem. 2022 Feb;14(2):196-207. doi: 1
    Insert
    A1-LCD+7R+10D (HNRNPA1 Human)
    Tags
    6xHis
    Expression
    Bacterial
    Mutation
    seven Arg residues added, ten Glu residues added
    Available Since
    March 8, 2022
    Availability
    Academic Institutions and Nonprofits only
    178677-plasmid-map-sequence-id-356191

    Enlarge

  46. A1-LCD-12F+12Y

    Plasmid
    #178659
    Purpose
    Bacterial expression of N-terminally 6His tagged A1-LCD with twelve Phe residues replaced with Tyr (LCD: low-complexity domain, aa 186-320)
    Depositor
    Tanja Mittag
    Article
    Bremer et al Nat Chem. 2022 Feb;14(2):196-207. doi: 1
    Insert
    A1-LCD -12F+12Y (HNRNPA1 Human)
    Tags
    6xHis
    Expression
    Bacterial
    Mutation
    twelve Phe residues replaced with Tyr
    Available Since
    March 8, 2022
    Availability
    Academic Institutions and Nonprofits only
    178659-plasmid-map-sequence-id-356187

    Enlarge

  47. A1-LCD-23S+23T

    Plasmid
    #178693
    Purpose
    Bacterial expression of N-terminally 6His tagged A1-LCD with twenty-three Thr reisudes replaced with Ser (LCD: low-complexity domain, aa 186-320)
    Depositor
    Tanja Mittag
    Article
    Bremer et al Nat Chem. 2022 Feb;14(2):196-207. doi: 1
    Insert
    A1-LCD-23S+23T (HNRNPA1 Human)
    Tags
    6xHis
    Expression
    Bacterial
    Mutation
    twenty-three Thr reisudes replaced with Ser
    Available Since
    March 8, 2022
    Availability
    Academic Institutions and Nonprofits only
    178693-plasmid-map-sequence-id-356186

    Enlarge

  49. A1-LCD-20G+20S

    Plasmid
    #178683
    Purpose
    Bacterial expression of N-terminally 6His tagged A1-LCD with twenty Gly residues replaced with Ser (LCD: low-complexity domain, aa 186-320)
    Depositor
    Tanja Mittag
    Article
    Bremer et al Nat Chem. 2022 Feb;14(2):196-207. doi: 1
    Insert
    A1-LCD-20G+20S (HNRNPA1 Human)
    Tags
    6xHis
    Expression
    Bacterial
    Mutation
    twenty Gly residues replaced with Ser
    Available Since
    March 8, 2022
    Availability
    Academic Institutions and Nonprofits only
    178683-plasmid-map-sequence-id-356148

    Enlarge

Showing: 7801 - 7850 of 9355 results