Purpose
AAV plasmid with human synapsin promoter driving mCh and BoNT/B amino acids 1-146 fused to iLID(V416I), separated with an IRES element. Co-express with SSPB-BoNT(147-441, Y365A) for sPA-BoNT
Insert
mCh-IRES-BoNT/B(1-146)-iLID
Mutation
iLID contains long lived V416I mutation
Available Since
March 19, 2019
Availability
Academic Institutions and Nonprofits only