We narrowed to 24,459 results for: Spr

1. pLentiCrisprV2 sgRNA hPER2c-term #1

   Plasmid

   #179454

   Purpose

   Lentiviral Crispr/Cas9 plasmid targeting hPER2 at C-terminus to generate C-terminal knock-in

   Depositor

   Achim Kramer

   Article

   Gabriel et al Nat Commun. 2021 Jun 18;12(1):3796. doi:

   Insert

   sgRNA targeting human PER2
   

   Use

   CRISPR and Lentiviral

   Promoter

   hU6

   Available Since

   March 29, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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2. pLentiCrisprV2 sgRNA hPER2c-term #2

   Plasmid

   #179455

   Purpose

   Lentiviral Crispr/Cas9 plasmid targeting hPER2 at C-terminus to generate C-terminal knock-in

   Depositor

   Achim Kramer

   Article

   Gabriel et al Nat Commun. 2021 Jun 18;12(1):3796. doi:

   Insert

   sgRNA targeting human PER2
   

   Use

   CRISPR and Lentiviral

   Promoter

   hU6

   Available Since

   March 29, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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3. pLentiCrisprV2 sgRNA hPER2c-term #3

   Plasmid

   #179456

   Purpose

   Lentiviral Crispr/Cas9 plasmid targeting hPER2 at C-terminus to generate C-terminal knock-in

   Depositor

   Achim Kramer

   Article

   Gabriel et al Nat Commun. 2021 Jun 18;12(1):3796. doi:

   Insert

   sgRNA targeting human PER2
   

   Use

   CRISPR and Lentiviral

   Promoter

   hU6

   Available Since

   March 29, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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4. pYJ34-PB-CRISPR-BANCR-E1-gRNA

   Plasmid

   #131077

   Purpose

   long non-coding RNA BANCR knock out

   Depositor

   Xiaojun Lian

   Article

   Jiang et al Bioact Mater. 2022 Feb 7;14:313-320. doi

   Insert

   BANCR Exon1 gRNA (BANCR Human)
   

   Use

   CRISPR

   Expression

   Mammalian

   Available Since

   May 19, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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5. pLentiCRISPRv2-TRAF6-targeting sgRNA 2

   Plasmid

   #131346

   Purpose

   gRNA targeting mouse TRAF6

   Depositor

   Jonathan Kagan

   Article

   Tan et al Cell. 2019 Apr 4;177(2):384-398.e11. doi

   Insert

   gRNA targeting mouse TRAF6 (Traf6 Mouse)
   

   Use

   Lentiviral

   Expression

   Mammalian

   Available Since

   Sept. 18, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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6. Anti-CASPR2 [K67/25R]

   Plasmid

   #177446

   Purpose

   Mammalian Expression Plasmid of anti-CASPR2 (Human). Derived from hybridoma K67/25.

   Depositor

   James Trimmer

   Article

   Mitchell et al Sci Rep. 2023 Sep 27;13(1):16200. doi: 1

   Insert

   anti-CASPR2 (Homo sapiens) recombinant mouse monoclonal antibody (CNTNAP2 Mouse)
   

   Expression

   Mammalian

   Promoter

   Dual CMV

   Available Since

   Nov. 12, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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7. pLentiCRISPR v2 puro hGSDME gRNA2

   Plasmid

   #223520

   Purpose

   Knocking out hGSDME in human cells

   Depositor

   Judy Lieberman

   Article

   Zhang et al Nature. 2020 Mar;579(7799):415-420. doi:

   Insert

   GSDME (GSDME Human)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Available Since

   Sept. 11, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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8. LentiCRISPR v2-sgAMPK alpha2 clone1

   Plasmid

   #162122

   Purpose

   Lentiviral sgRNA plasmid targeting human AMPK alpha2

   Depositor

   Boyi Gan

   Article

   Lee et al Nat Cell Biol. 2020 Feb;22(2):225-234. d

   Insert

   sgAMPK alpha2 (PRKAA2 Human)
   

   Use

   Lentiviral

   Available Since

   Jan. 26, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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9. pMTP170 (pBAD33_CRISPR(Tn6900)-entry)

   Plasmid

   #164263

   Purpose

   Entry vector for cloning user-defined spacers in the Tn6900 CRISPR array.

   Depositor

   Joseph Peters

   Article

   Petassi et al Cell. 2020 Nov 30. pii: S0092-8674(20)31

   Type

   Empty backbone

   Expression

   Bacterial

   Promoter

   Arabinose

   Available Since

   Jan. 25, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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10. plentiCRISPR-v2 Puro KIAA0141/DELE1_sg1

    Plasmid

    #218524

    Purpose

    sgRNA targeting human KIAA0141/DELE1

    Depositor

    Kivanc Birsoy

    Article

    Kenny et al Cell Metab. 2023 Jun 6;35(6):1057-1071.e

    Insert

    DELE1 (DELE1 Human)
    

    Use

    CRISPR and Lentiviral

    Available Since

    July 30, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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11. plentiCRISPR-v2 Puro KIAA0141/DELE1_sg2

    Plasmid

    #218525

    Purpose

    sgRNA targeting human KIAA0141/DELE1

    Depositor

    Kivanc Birsoy

    Article

    Kenny et al Cell Metab. 2023 Jun 6;35(6):1057-1071.e

    Insert

    DELE1 (DELE1 Human)
    

    Use

    CRISPR and Lentiviral

    Available Since

    June 12, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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12. R777-E322 Hs.SPRED1-nostop

    Plasmid

    #70606

    Purpose

    Gateway ORF clone of human SPRED1 [NM_152594.2] without stop codon (for C-terminal fusions)

    Depositor

    Dominic Esposito

    Insert

    SPRED1 (SPRED1 Human)
    

    Use

    Gateway entry clone

    Available Since

    March 1, 2016

    Availability

    Academic Institutions and Nonprofits only

    

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13. pSH-Csy4-T2A-SpRFN

    Plasmid

    #85754

    Purpose

    Expresses S. pyogenes FokI-dCas9-NLS with a 25 amino acid linker (GGGGS)5 fusion. Also expresses Csy4 for cleavage of multiplexed gRNA transcripts. Derived from pSQT1601 (Addgene #53369).

    Depositor

    Lawrence Stanton

    Article

    Havlicek et al Mol Ther. 2017 Feb 1;25(2):342-355. doi:

    Insert

    Csy4-T2A-FokI-dCas9
    

    Use

    CRISPR

    Tags

    Csy4 and FokI fusion via 25 amino acid (GGGGS)5 l…

    Expression

    Mammalian

    Mutation

    D10A, H840A

    Promoter

    CAG

    Available Since

    Jan. 20, 2017

    Availability

    Academic Institutions and Nonprofits only

    

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14. R777-E330 Hs.SPRY2-nostop

    Plasmid

    #70614

    Purpose

    Gateway ORF clone of human SPRY2 [NM_005842.2] without stop codon (for C-terminal fusions)

    Depositor

    Dominic Esposito

    Insert

    SPRY2 (SPRY2 Human)
    

    Use

    Gateway entry clone

    Available Since

    March 1, 2016

    Availability

    Academic Institutions and Nonprofits only

    

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15. R777-E334 Hs.SPRY4-nostop

    Plasmid

    #70617

    Purpose

    Gateway ORF clone of human SPRY4 [NM_001127496.1] without stop codon (for C-terminal fusions)

    Depositor

    Dominic Esposito

    Insert

    SPRY4 (SPRY4 Human)
    

    Use

    Gateway entry clone

    Available Since

    March 1, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

16. R777-E328 Hs.SPRY1-nostop

    Plasmid

    #70612

    Purpose

    Gateway ORF clone of human SPRY1 [NM_001258038.1] without stop codon (for C-terminal fusions)

    Depositor

    Dominic Esposito

    Insert

    SPRY1 (SPRY1 Human)
    

    Use

    Gateway entry clone

    Available Since

    March 1, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. R777-E324 Hs.SPRED2-nostop

    Plasmid

    #70608

    Purpose

    Gateway ORF clone of human SPRED2 [NM_181784.2] without stop codon (for C-terminal fusions)

    Depositor

    Dominic Esposito

    Insert

    SPRED2 (SPRED2 Human)
    

    Use

    Gateway entry clone

    Available Since

    March 1, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. L-CRISPR-CTN (MLL-ctrl)

    Plasmid

    #69215

    Purpose

    Advanced lentiviral CRISPR-Cas9 vector for induction of chromosomal translocations; control, MLL-sgRNA + luciferase-sgRNA

    Depositor

    Dirk Heckl

    Article

    Reimer et al Haematologica. 2017 Jun 1. pii: haematol

    Inserts

    SpCas9
    Sp sgRNA scaffold
    SFFV promoter
    P2A-mNeonGreen
    

    Use

    CRISPR and Lentiviral

    Tags

    FLAG

    Available Since

    June 5, 2017

    Availability

    Academic Institutions and Nonprofits only

    

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19. pFRT/TO/GFP-SCAF4 (CRISPR_resistant)

    Plasmid

    #122471

    Purpose

    Dox-inducible GFP (N-terminal tag) SCAF4 expression

    Depositor

    Jesper Svejstrup

    Article

    Gregersen et al Cell. 2019 May 10. pii: S0092-8674(19)30

    Insert

    SCAF4 (SCAF4 Human)
    

    Tags

    GFP

    Expression

    Mammalian

    Mutation

    Synonymous mutations conferring resistance to gRN…

    Promoter

    CMV

    Available Since

    May 16, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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20. R777-E332 Hs.SPRY3-nostop

    Plasmid

    #70616

    Purpose

    Gateway ORF clone of human SPRY3 [NM_005840.2] without stop codon (for C-terminal fusions)

    Depositor

    Dominic Esposito

    Insert

    SPRY3 (SPRY3 Human)
    

    Use

    Gateway entry clone

    Available Since

    March 1, 2016

    Availability

    Academic Institutions and Nonprofits only

    

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