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Plasmid#167528PurposeDual-color fluorescent reporter for the creation and detection of Cre-dependent tunable mosaics in floxed mouse lines and cells.DepositorInsertBeatrix
UseCre/Lox and Mouse TargetingTagsExpressionMammalianMutationPromoterCAGAvailable sinceApril 30, 2021AvailabilityAcademic Institutions and Nonprofits only -
pCAG-DIO-inv[roxSTOProx-EB3 mNeonGreen-bGH]
Plasmid#196885PurposeDual Cre/Dre-dependent expression of EB3-mNeon. Used as functional (labelling of microtubule plus ends) Cre-Dre cotransfection reporterDepositorInsertroxSTOProx-EB3 mNeonGreen-bGH (MAPRE3 Human)
UseCre/Lox; Dre/roxTagsExpressionMammalianMutationPromoterQuimeric CAGAvailable sinceMay 17, 2023AvailabilityAcademic Institutions and Nonprofits only -
pCAG-tdTHC
Plasmid#112621Purposeexpression plasmid with CAG promoter driving multicistronic cassette H2BtdTomato_p2A_HygroR_p2A_CreERt2DepositorInsertsUseCre/LoxTagstdTomatoExpressionMammalianMutationPromoterCAGAvailable sinceSept. 13, 2018AvailabilityAcademic Institutions and Nonprofits only -
Lenti-SAM-Cre
Plasmid#198714PurposeFor expression of guide RNAs, the SAM transcriptional activator for CRISPRa and Cre in mammalian cellsDepositorInsertsU6-MS2-gRNAscaffold
Pgk-MPH-Cre
UseCre/Lox and LentiviralTagsExpressionMammalianMutationPromoterPgk and U6Available sinceJan. 7, 2025AvailabilityAcademic Institutions and Nonprofits only -
pCAG-rox-inv[Talpha1-iCre-pA]-rox-mNeonGreen-hCentrin1
Plasmid#196892PurposeNeuron-specific expression of human (h)Centrin fused to mNeonGreen. Used in combination with Talpha1-Dre-pA plasmidsDepositorInsertmNeonGreen-hCentrin1 (CETN1 Human)
UseCre/LoxTagsExpressionMammalianMutationPromoterQuimeric CAGAvailable sinceMay 17, 2023AvailabilityAcademic Institutions and Nonprofits only -
LeGO-iBSD-5LO-d4
Plasmid#182743PurposeLentiviral expression vector for codon-optimized 5-Lipoxygenase (isoform delta 4) in mamallian cells with blasticidin S resistance (bsd).DepositorInsert5-Lipoxygenase isoform delta 4 (ALOX5 Human)
UseCre/Lox and LentiviralTagsExpressionMammalianMutationcodon optimized for expression in homo sapiensPromoterSFFVAvailable sinceJuly 26, 2022AvailabilityAcademic Institutions and Nonprofits only -
LeGO-iBSD-5LO-p12
Plasmid#182744PurposeLentiviral expression vector for codon-optimized 5-Lipoxygenase (isoform p12) in mamallian cells with blasticidin S resistance (bsd).DepositorInsert5-Lipoxygenase isoform p12 (ALOX5 Human)
UseCre/Lox and LentiviralTagsExpressionMammalianMutationcodon optimized for expression in homo sapiensPromoterSFFVAvailable sinceJuly 26, 2022AvailabilityAcademic Institutions and Nonprofits only -
LeGO-iBSD-5LO-E376Q
Plasmid#182742PurposeLentiviral expression vector for codon-optimized 5-Lipoxygenase (enzymatically inactive E376Q mutant) in mamallian cells with blasticidin S resistance (bsd).DepositorInsert5-Lipoxygenase E376Q (ALOX5 Human)
UseCre/Lox and LentiviralTagsExpressionMammalianMutationenzymatically inactive 5-LO E376Q mutant, codon o…PromoterSFFVAvailable sinceJuly 26, 2022AvailabilityAcademic Institutions and Nonprofits only -
LeGO-iBSD-5LO-d13
Plasmid#182745PurposeLentiviral expression vector for codon-optimized 5-Lipoxygenase (isoform delta 13) in mamallian cells with blasticidin S resistance (bsd).DepositorInsert5-Lipoxygenase isoform delta 13 (ALOX5 Human)
UseCre/Lox and LentiviralTagsExpressionMammalianMutationcodon optimized for expression in homo sapiensPromoterAvailable sinceJuly 26, 2022AvailabilityAcademic Institutions and Nonprofits only -
pAAV-FLEX-tdTomato
Plasmid#28306DepositorHas ServiceAAV PHP.S, AAV PHP.eB, AAV Retrograde, AAV1, AAV2, AAV5, AAV8, and AAV9InserttdTomato
UseAAV and Cre/Lox; Adeno-associated virusTagsExpressionMammalianMutationN/APromoterCAGAvailable sinceSept. 7, 2012AvailabilityAcademic Institutions and Nonprofits only -
miR-124
Plasmid#182363PurposePlasmid with 4x miR-124 target sitesDepositorInsert4x miR-124 target sites
UseCre/Lox and Synthetic BiologyTagsExpressionMammalianMutationPromoterAvailable sinceMarch 31, 2022AvailabilityAcademic Institutions and Nonprofits only -
pAAV-synP-FLEX-TVA66T-EGFP-B19G
Plasmid#64097PurposeExpresses TVA66T-EGFP-B19G under the synapsin promotorDepositorInsertTVA66T-EGFP-B19G
UseAAV and Cre/LoxTagsEGFPExpressionMammalianMutationGlutamic acid 66 to ThreoninePromotersynapsinAvailable sinceApril 7, 2015AvailabilityAcademic Institutions and Nonprofits only -
pBCSK_LEU2_I
Plasmid#109060Purposeyeast shuttle vector for insertion into yeast chromosomes in pBCSK backbone. LoxP sites upstream of LEU2. For teaching purposesDepositorInsertLEU2 (LEU2 Budding Yeast, Zygosaccharomyces rouxii)
UseCre/LoxTagsExpressionBacterial and YeastMutationPromoterLEU2Available sinceAug. 1, 2018AvailabilityAcademic Institutions and Nonprofits only -
AiP1999 - pAAV-AiE2255m-minBG-iCre(R297T)-BGHpA
Plasmid#223843PurposeEnhancer-driven expression of the iCre(R297T) recombinase in thalamic PVT neuronsDepositorInsertiCre(R297T)
UseAAVTagsExpressionMutationArgenine in aa297 was replaced with ThreoninePromoterminBGAvailable sinceAug. 28, 2024AvailabilityAcademic Institutions and Nonprofits only -
pAAV hSyn GFP-Cre
Plasmid#175381Purposeexpresses GFP-Cre under the control of a human synapsin promoterDepositorInsertGFP-Cre recombinase
UseAAVTagsCre is fused to GFP. GFP is fused to additional n…ExpressionMutationPromoterhuman synapsinAvailable sinceNov. 30, 2021AvailabilityAcademic Institutions and Nonprofits only -
pCDH-CB-iCre-P2A-tdTomato-T2A-Puro
Plasmid#72255PurposeExpress iCre, tdTomato and puromycin resistance gene (puromycin N-acetyl-transferase) under CB (chicken beta-actin + CMV enhancer) promoterDepositorInsertiCre-P2A-tdTomato-T2A-Puro
UseLentiviralTagsExpressionMammalianMutationPromoterCB and chicken beta-actin + CMV enhancerAvailable sinceMarch 1, 2017AvailabilityAcademic Institutions and Nonprofits only -
AiP2017 - pAAV-AiE0774m-minBG-iCre(R297T)-BGHpA
Plasmid#220723PurposeAiE0774m is an enhancer sequence, designed to induce cre-dependent recombination in specific populations of brain cellsInsertiCre(R297T)
UseAAVTagsExpressionMutationPromoterminBGAvailable sinceMarch 17, 2025AvailabilityAcademic Institutions and Nonprofits only -
pAAV-hSyn-con/fon DREADD Gq-mCherry
Plasmid#200661PurposeConstruct for chemogenetically activating and visualizing subpopulations of neurons in the retinaDepositorInsertDREADD Gq-mCherry
UseAAV, Cre/Lox, and Mouse Targeting ; IntrsectTagsmCherryExpressionMammalianMutationPromoterhSynAvailable sinceNov. 13, 2024AvailabilityAcademic Institutions and Nonprofits only -
AiP20027 - pAAV-AiE2182m_3xC2-minBG-iCre(R297T)-BGHpA
Plasmid#220735PurposeAiE2182m_3xC2 is an optimized enhancer sequence, designed to induce cre-dependent recombination in specific populations of brain cellsInsertiCre(R297T)
UseAAVTagsExpressionMutationPromoterminBGAvailable sinceFeb. 25, 2025AvailabilityAcademic Institutions and Nonprofits only -
AAV-DIO-TVA-2A-oG
Plasmid#178431PurposeExpresses TVA and optimized Rabies G (oG) protein in a FLEX cassetteDepositorInsertsTVA950
Optimized G
UseAAV and Cre/Lox; Adeno-associated virusTagsExpressionMutationPromoterhSynAvailable sinceFeb. 17, 2022AvailabilityAcademic Institutions and Nonprofits only