380 results

1. Sabatini/Lander Lab Activity-Optimized Genome-wide Human sgRNA Library in lentiCRISPR v1

   Pooled Library

   #1000000100

   Purpose

   CRISPR gRNA knockout pooled library (version 1) for targeting the human genome

   Depositor

   David Sabatini, Eric Lander

   Available since

   April 3, 2017

   Availability

   Academic Institutions and Nonprofits only

2. E.coli_GW-sgRNA_Lib4

   Pooled Library

   #113137

   Purpose

   Genome-wide gRNA library for E. coli, sub4

   Depositor

   Chong Zhang

   Article

   Wang et al Nat Commun. 2018 Jun 26;9(1):2475. doi:

   Expression

   Bacterial

   Available since

   May 14, 2019

   Availability

   Academic Institutions and Nonprofits only

3. E.coli_GW-sgRNA_Lib2

   Pooled Library

   #113135

   Purpose

   Genome-wide gRNA library for E. coli, sub2

   Depositor

   Chong Zhang

   Article

   Wang et al Nat Commun. 2018 Jun 26;9(1):2475. doi:

   Expression

   Bacterial

   Available since

   May 14, 2019

   Availability

   Academic Institutions and Nonprofits only

4. Mouse CRISPRi sgRNA library Dolomiti in backbone XPR_050, Set A

   Pooled Library

   #104090

   Purpose

   Crispri

   Depositor

   John Doench, David Root

   Article

   Sanson et al Nat Commun. 2018 Dec 21;9(1):5416. doi:

   Use

   Lentiviral

   Available since

   July 13, 2018

   Availability

   Academic Institutions and Nonprofits only

5. E.coli_NC_sgRNA_lib

   Pooled Library

   #113146

   Purpose

   Genome-wide gRNA library for E. coli, non-targeting control

   Depositor

   Chong Zhang

   Article

   Wang et al Nat Commun. 2018 Jun 26;9(1):2475. doi:

   Expression

   Bacterial

   Available since

   May 14, 2019

   Availability

   Academic Institutions and Nonprofits only

6. pre-associated oBC-minP-GFP-mBC backbone (p043)

   Pooled Library

   #194098

   Purpose

   pre-associated oBC-minP-GFP-mBC backbone (p043), can directly be used to deposit library of regulatory elements

   Depositor

   Jay Shendure

   Article

   Lalanne et al bioRxiv 2022.12.10.519236

   Expression

   Bacterial and Mammalian

   Use

   RNAi

   Available since

   April 3, 2024

   Availability

   Academic Institutions and Nonprofits only

7. mCRISPRa-v2, Kinases, Phosphatases, and Drug Targets (m1), top 5 sgRNAs/gene

   Pooled Library

   #83998

   Purpose

   Mouse CRISPRi Pooled Library tartgeting kinsases, phosphatases and Drug Targets

   Depositor

   Jonathan Weissman

   Article

   Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

   Available since

   Jan. 12, 2017

   Availability

   Academic Institutions and Nonprofits only

8. Human messenger-RBP sgRNA library

   Pooled Library

   #168791

   Purpose

   CRISPR library targets sub-pool of human mRNA binding proteins

   Depositor

   Martin Turner

   Article

   Turner et al CRISPR J. 2021 Jun;4(3):427-437. doi: 10

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   July 30, 2021

   Availability

   Academic Institutions and Nonprofits only

9. Liu Lab MusCK Library A

   Pooled Library

   #174196

   Purpose

   MusCK library contains 23,622 unique sgRNAs targeting 4,787 gene locations in the genome. Sub-library MusCK A contains 5 gRNAs per gene.

   Depositor

   Xiaole Shirley Liu

   Article

   Wang et al Cell. 2021 Oct 14;184(21):5357-5374.e22.

   Expression

   Mammalian

   Species

   Mus musculus

   Use

   CRISPR and Lentiviral

   Available since

   Oct. 29, 2021

   Availability

   Academic Institutions and Nonprofits only

10. mCRISPRi-v2, Cancer and Apoptosis (m2), top 5 sgRNAs/gene

    Pooled Library

    #83990

    Purpose

    Mouse CRISPRi Pooled Library targeting cancer and apoptosis genes

    Depositor

    Jonathan Weissman

    Article

    Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

    Available since

    Jan. 12, 2017

    Availability

    Academic Institutions and Nonprofits only

11. hCRISPRi_dual_5_6

    Pooled Library

    #187248

    Purpose

    Ultra-compact, human genome-wide CRISPRi library targeting each gene with a single element encoding a dual sgRNA cassette.

    Depositor

    Jonathan Weissman, Marco Jost

    Article

    Replogle et al eLife. 2022 Dec 28;11:e81856. doi: 10.75

    Species

    Synthetic

    Use

    Lentiviral

    Available since

    Sept. 30, 2022

    Availability

    Academic Institutions and Nonprofits only

12. TP53 MITE Library

    Pooled Library

    #113569

    Purpose

    Pooled lentiviral plasmid library containing ~8,000 single amino acid substitution and nonsense mutant variants of p53

    Depositor

    William Hahn, David Root

    Article

    Giacomelli et al Nat Genet. 2018 Oct;50(10):1381-1387. do

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    Lentiviral

    Available since

    Jan. 4, 2019

    Availability

    Academic Institutions and Nonprofits only

13. E.coli_GW-sgRNA_Lib5

    Pooled Library

    #113138

    Purpose

    Genome-wide gRNA library for E. coli, sub5

    Depositor

    Chong Zhang

    Article

    Guo et al Nucleic Acids Res. 2018 Aug 21;46(14):70

    Expression

    Bacterial

    Available since

    May 14, 2019

    Availability

    Academic Institutions and Nonprofits only

14. mCRISPRi-v2, Mitochondria, Trafficking, and Motility (m4), top 5 sgRNAs/gene

    Pooled Library

    #83992

    Purpose

    Mouse CRISPRi Pooled Library targeting Mitochondria, Trafficking, and Motility genes

    Depositor

    Jonathan Weissman

    Article

    Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

    Available since

    Jan. 12, 2017

    Availability

    Academic Institutions and Nonprofits only

15. p11-3’_8xN_PAM-site1 (RTW554)

    Pooled Library

    #160132

    Purpose

    Plasmid library harboring a randomized 8nt PAM 3’ of target site 1. Can be used to profile CRISPR-Cas PAM requirements of enzymes that recognize 3’ PAMs (e.g. Cas9)

    Depositor

    Keith Joung, Benjamin Kleinstiver

    Article

    Walton et al Nat Protoc. 2021 Feb 5. pii: 10.1038/s41

    Species

    Synthetic

    Use

    CRISPR

    Available since

    Feb. 8, 2021

    Availability

    Academic Institutions and Nonprofits only

16. mCRISPRi-v2, Unassigned (m7), top 5 sgRNAs/gene

    Pooled Library

    #83995

    Purpose

    Mouse CRISPRi Pooled Library targeting unassigned genes

    Depositor

    Jonathan Weissman

    Article

    Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

    Available since

    Jan. 12, 2017

    Availability

    Academic Institutions and Nonprofits only

17. Liu Lab MusCK (A + B)

    Pooled Library

    #1000000178

    Depositor

    Xiaole Shirley Liu

    Available since

    Oct. 29, 2021

    Availability

    Academic Institutions and Nonprofits only

18. mCRISPRa-v2, genome-wide, 10 sgRNAs/gene

    Pooled Library

    #1000000093

    Purpose

    Genome-wide CRISPR gRNA pooled library for activation of mouse genes

    Depositor

    Jonathan Weissman

    Available since

    Nov. 15, 2016

    Availability

    Academic Institutions and Nonprofits only

19. TRE-MPRA_minPromega Library

    Pooled Library

    #201013

    Purpose

    Massively parallel reporter assay (MPRA) library with minPromega promoter

    Depositor

    Justin English

    Article

    Zahm et al bioRxiv. 2023 May 11:2023.05.11.539703.

    Expression

    Mammalian

    Use

    Luciferase

    Available since

    Oct. 31, 2023

    Availability

    Academic Institutions and Nonprofits only

20. ClonTracer Barcoding Library (7.5 ug)

    Pooled Library

    #69830

    Purpose

    High complexity 30bp-long semi random DNA barcode library in lentiviral backbone

    Depositor

    Frank Stegmeier

    Article

    Bhang et al Nat Med. 2015 Apr 13. doi: 10.1038/nm.38

    Expression

    Mammalian

    Species

    Synthetic

    Use

    Lentiviral

    Available since

    Sept. 11, 2015

    Availability

    Academic Institutions and Nonprofits only