390 results

#187247

Ultra-compact, human genome-wide CRISPRi library targeting each gene with a single element encoding a dual sgRNA cassette.

Marco Jost, Jonathan Weissman

Replogle et al eLife. 2022 Dec 28;11:e81856. doi: 10.75

Sept. 30, 2022

Academic Institutions and Nonprofits only

#86540

Jonathan Weissman

Liu et al Science. 2017 Jan 06. Vol. 355, Issue 63

March 8, 2017

Academic Institutions and Nonprofits only

#153101

CRISPR library targets all non-essential and conditionally essential transporter genes in S. cerevisiae

Irina Borodina

Wang et al Metab Eng. 2021 Jan 16. pii: S1096-7176(

Jan. 20, 2021

Academic Institutions and Nonprofits only

#1000000232

Tyler Starr

Oct. 25, 2023

Academic Institutions and Nonprofits only

#138084

Targets 3' splice sites with paired gRNAs. Induces skipping of poison cassette exons and matching upstream constitutive exons. Compare loss of a constitutive coding exon with loss of a poison exon.

Robert Bradley

Thomas et al Nat Genet. 2020 Jan;52(1):84-94. doi: 10

March 6, 2020

Academic Institutions and Nonprofits only

#216134

Library of intron-targeting sgRNAs for pooled tagging of proteins with GFP or other protein tags at their endogenous genomic locus using an intron tagging approach.

Stefan Kubicek

Reicher et al Nat Cell Biol. 2024 May;26(5):745-756. d

April 19, 2024

Academic Institutions and Nonprofits only

#216133

Library of intron-targeting sgRNAs for pooled tagging of proteins with GFP or other protein tags at their endogenous genomic locus using an intron tagging approach.

Stefan Kubicek

Reicher et al Nat Cell Biol. 2024 May;26(5):745-756. d

April 19, 2024

Academic Institutions and Nonprofits only

#92352

Focused gRNA library that targets synthetic lethal candidate and control genes with oncogenic Ras.

Eric Lander, David Sabatini

Wang et al Cell. 2017 Feb 1. pii: S0092-8674(17)300

June 7, 2017

Academic Institutions and Nonprofits only

#86542

Jonathan Weissman

Liu et al Science. 2017 Jan 06. Vol. 355, Issue 63

March 8, 2017

Academic Institutions and Nonprofits only

#1000000239

Jay Shendure

April 3, 2024

Academic Institutions and Nonprofits only

#221409

gRNA library to test the impact of transporters on biological processes

RESOLUTE Consortium, Giulio Superti-Furga

Wolf et al Cell Chem Biol. 2024 Dec 24:S2451-9456(2

Sept. 13, 2024

Academic Institutions and Nonprofits only

#113584

AAV-CRISPR library for pool mutagenesis of top tumor suppressor genes

Sidi Chen

Wang et al Sci Adv. 2018 Feb 28;4(2):eaao5508. doi:

July 23, 2019

Academic Institutions and Nonprofits only

#180272

Tiles the entire ~154 kb of the BAC16 Kaposi’s Sarcoma-associated Herpes Virus genome. A guide every ~8 bp allows pooled screening of the viral genome.

Britt Glaunsinger

Morgens et al PLoS Pathog. 2022 Jan 18;18(1):e1010236.

Feb. 11, 2022

Academic Institutions and Nonprofits only

#190744

Targets proximal poly(A) signal sequences in genes identified to be differentially polyadenylated in the mouse B16-F10 melanoma system.

Robert Bradley

Gabel et al Nat Commun. 2024 Feb 1;15(1):959. doi: 1

Feb. 2, 2024

Academic Institutions and Nonprofits only

#174197

MusCK library contains 23,622 unique sgRNAs targeting 4,787 gene locations in the genome. Sub-library MusCK M_b contains 5 gRNAs per gene.

Xiaole Shirley Liu

Wang et al Cell. 2021 Oct 14;184(21):5357-5374.e22.

Oct. 29, 2021

Academic Institutions and Nonprofits only

#86546

Jonathan Weissman

Liu et al Science. 2017 Jan 06. Vol. 355, Issue 63

March 8, 2017

Academic Institutions and Nonprofits only

#1000000188

Jesse Bloom

June 14, 2022

Academic Institutions and Nonprofits only

#1000000248

Tyler Starr

Sept. 6, 2024

Academic Institutions and Nonprofits only

#86547

Jonathan Weissman

Liu et al Science. 2017 Jan 06. Vol. 355, Issue 63

March 8, 2017

Academic Institutions and Nonprofits only

#83977

Human CRISPRi Pooled Library targeting unassigned genes

Jonathan Weissman

Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

Dec. 14, 2016

Academic Institutions and Nonprofits only

#209736

CHyMErA Exon Deletion hgRNA Library allows identification of frame-preserving exons that affect cell fitness in human cells using the CHyMErA screening platform.

Thomas Gonatopoulos-Pournatzis

Xiao et al Mol Cell. 2024 Jul 11;84(13):2553-2572.e

June 20, 2024

Academic Institutions and Nonprofits only

#86549

Jonathan Weissman

Liu et al Science. 2017 Jan 06. Vol. 355, Issue 63

March 8, 2017

Academic Institutions and Nonprofits only

#86548

Jonathan Weissman

Liu et al Science. 2017 Jan 06. Vol. 355, Issue 63

March 8, 2017

Academic Institutions and Nonprofits only

#86545

Jonathan Weissman

Liu et al Science. 2017 Jan 06. Vol. 355, Issue 63

March 8, 2017

Academic Institutions and Nonprofits only

#173195

Knockout library targeting human E-boxes genome-wide.

Agnieszka Dzikiewicz-Krawczyk

Kazimierska et al Mol Oncol. 2023 Nov;17(11):2295-2313. do

Aug. 11, 2021

Academic Institutions and Nonprofits only

#207478

HA-GD2-28z CAR in combination with 100 transcription factors (and related proteins) and 2 controls (GFP/RFP). Library can be used to generate HDR templates for modular pooled knockin (ModPoKI) into th

Alexander Marson

Blaeschke et al Cell. 2023 Sep 14;186(19):4216-4234.e33.

Jan. 26, 2024

Academic Institutions and Nonprofits only

#207480

HA-GD2-28z CAR in combination with ~10,000 transcription factor combinations (and related proteins) and controls (GFP/RFP combinations). Library can be used to generate HDR templates for modular poole

Alexander Marson

Blaeschke et al Cell. 2023 Sep 14;186(19):4216-4234.e33.

Jan. 26, 2024

Academic Institutions and Nonprofits only

#64750

Library designed for genomic targeting and screening in Drosophila cells. All possible gRNA target sites within the shared exonic regions on either DNA strand of the Drosophila genome were computed.

Ji-Long Liu

Bassett et al J Genet Genomics. 2015 Jun 20;42(6):301-

March 7, 2016

Academic Institutions and Nonprofits only

#75313

Human sgRNA library in backbone lentiGuide-Puro targeting 763 kinase genes and containing 3,052 unique sgRNAs along with 100 non-targeting controls

John Doench, David Root

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

June 27, 2016

Academic Institutions and Nonprofits only

#62843

amplified library of Salpingoeca rosetta

Nicole King

Fairclough et al Genome Biol. 2013 Feb 18;14(2):R15. doi:

June 16, 2015

Academic Institutions and Nonprofits only