390 results

#140219

Knockout library targeting human DNA damage response and DNA repair genes.

Junjie Chen

Su et al DNA Repair (Amst). 2020 Jan 16;87:102803

Aug. 20, 2021

Academic Institutions and Nonprofits only

#164896

Genome-wide knockout library designed with two sgRNAs per gene.

Mathew Garnett

Gonçalves et al Genome Biol. 2021 Jan 21;22(1):40. doi:

May 20, 2021

Academic Institutions and Nonprofits only

#1000000264

Michael Birnbaum

Aug. 12, 2025

Academic Institutions and Nonprofits only

#187080

Library targeting 2,989 human metabolic genes for activation of gene expression.

Kivanc Birsoy

Unlu et al Mol Cell. 2022 Aug 4;82(15):2832-2843.e7

Oct. 26, 2022

Academic Institutions and Nonprofits only

#160129

Targets mouse metabolic genes and includes most metabolic enzymes and transporters.

Kivanc Birsoy

Zhu et al Cell Metab. 2020 Oct 28. pii: S1550-4131

Nov. 10, 2020

Academic Institutions and Nonprofits only

#206248

The lipid metabolism library contains guide RNAs against 295 genes targeting mouse genes encoding enzymes that directly impact lipid metabolism.

Kivanc Birsoy

Soula et al Nature. 2024 Aug 7. doi: 10.1038/s41586-

Aug. 29, 2024

Academic Institutions and Nonprofits only

#1000000074

Genome-wide CRISPR gRNA pooled library for activation of mouse genes

Feng Zhang

March 17, 2016

Academic Institutions and Nonprofits only

#101926

Bassik lab Human CRISPR-Cas9 Deletion Library - Apoptosis and cancer. Coexpresses mCherry.

Michael Bassik

Morgens et al Nat Commun. 2017 May 5;8:15178. doi: 10.

May 23, 2018

Academic Institutions and Nonprofits only

#179851

Lentiviral barcode library that consists of 10^6 unique barcodes. Barcodes consist of 12bp degenerate region followed by two stable bases (C or G) and 4bp unique library code ACGT.

Jason Moffat

Rehman et al Cell. 2021 Jan 7;184(1):226-242.e21. doi

May 12, 2022

Academic Institutions and Nonprofits only

#84003

Mouse CRISPRa Pooled Library targeting membrane proteins

Jonathan Weissman

Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

Jan. 12, 2017

Academic Institutions and Nonprofits only

#92385

Crispri

John Doench, David Root

Sanson et al Nat Commun. 2018 Dec 21;9(1):5416. doi:

July 13, 2018

Academic Institutions and Nonprofits only

#187249

Ultra-compact, human genome-wide CRISPRi library targeting each gene with a single element encoding a dual sgRNA cassette.

Marco Jost, Jonathan Weissman

Replogle et al eLife. 2022 Dec 28;11:e81856. doi: 10.75

Sept. 30, 2022

Academic Institutions and Nonprofits only

#1000000131

Genome-wide CRISPR gRNA pooled library for inhibition of mouse genes

John Doench, David Root

July 13, 2018

Academic Institutions and Nonprofits only

#197348

To allow for genome-wide genetic modifier screening, the library has a second fixed non-targeting control guide.

Rebecca Voorhees, Jonathan Weissman

Guna et al BMC Genomics. 2023 Oct 30;24(1):651. doi

May 25, 2023

Academic Institutions and Nonprofits only

#179774

SPLINTR (Single-cell Profiling and LINeage TRacing) is a high diversity lentiviral barcode library for tracing clonal lineages using bulk and single-cell readouts.

Mark Dawson

Fennell et al Nature. 2022 Jan;601(7891):125-131. doi:

May 11, 2022

Academic Institutions and Nonprofits only

#136987

Designed for assays with limited cell numbers with 2 guides per gene. Compatible with John Doench’s Brie mouse genome-wide library.

John Doench

DeWeirdt et al Nat Commun. 2020 Feb 6;11(1):752. doi: 1

Feb. 24, 2020

Academic Institutions and Nonprofits only

#1000000126

CRISPR gRNA mouse knockout pooled library - Trafficking, mitochondrial, and motility

Michael Bassik

May 23, 2018

Academic Institutions and Nonprofits only

#75316

Mouse sgRNA library in backbone lentiGuide-Puro targeting 713 kinase genes and containing 2,852 unique sgRNAs along with 100 non-targeting controls

John Doench, David Root

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

June 27, 2016

Academic Institutions and Nonprofits only

#160134

Plasmid library harboring a randomized 10nt PAM 5’ of target site 3. Can be used to profile CRISPR-Cas PAM requirements of enzymes that recognize 5’ PAMs (e.g. Cas12a)

Keith Joung, Benjamin Kleinstiver

Walton et al Nat Protoc. 2021 Feb 5. pii: 10.1038/s41

Feb. 8, 2021

Academic Institutions and Nonprofits only

#179852

Lentiviral barcode library that consists of 10^6 unique barcodes. Barcodes consist of 12bp degenerate region followed by two stable bases (C or G) and 4bp unique library code CCAA.

Jason Moffat

Rehman et al Cell. 2021 Jan 7;184(1):226-242.e21. doi

May 12, 2022

Academic Institutions and Nonprofits only