Reference Icon RedbookMammalian RNAi Tools

Several laboratories have deposited plasmids for mammalian RNA interference experiments at Addgene’s non-profit plasmid repository. This website describes some of the empty vectors that you can use to clone shRNAs.

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Click here to browse a selection of mammalian RNAi plasmids from Addgene’s repository.

Nature Methods has published a user’s guide to RNA interference in mammalian cells. Further information for many of Addgene’s RNAi vectors can be found in these articles.