We narrowed to 40,297 results for: Spr

1. 1183_pAAV-U6-Ex14-gRNAd-CB-EmGFP

   Plasmid

   #89061

   Purpose

   AAV-gRNA targeting the murine Ldlr gene

   Depositor

   William Lagor

   Article

   Jarrett et al Sci Rep. 2017 Mar 16;7:44624. doi: 10.10

   Insert

   EmGFP
   

   Use

   AAV and CRISPR

   Expression

   Mammalian

   Promoter

   Chicken beta actin with partial CMV enhancer

   Available Since

   April 11, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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2. ADCK3 gRNA (BRDN0001147832)

   Plasmid

   #77321

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human ADCK3

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   ADCK3
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   hU6

   Available Since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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3. ADCK3 gRNA (BRDN0001146491)

   Plasmid

   #77323

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human ADCK3

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   ADCK3
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   hU6

   Available Since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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4. pLenti-sgCCR5

   Plasmid

   #83930

   Purpose

   Lentiviral vector expressing an sgRNA targeting CCR5 NOTE: This plasmid does NOT contain Cas9.

   Depositor

   David Sabatini

   Article

   Park et al Nat Genet. 2016 Dec 19. doi: 10.1038/ng.

   Insert

   sgCCR5
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   U6

   Available Since

   Feb. 1, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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5. pLV-CS-154

   Plasmid

   #166230

   Purpose

   lenti-U6-gRNA::CMVp-nCas9-PmCDA1-UGI-2A-mCherry

   Depositor

   Nozomu Yachie

   Article

   Fukushima et al Sci Rep. 2021 Dec 13;11(1):23889. doi: 1

   Inserts

   U6-gRNA EGFP targetting
   nCas9-PmCDA1-UGI-2A-mCherry
   

   Use

   CRISPR and Lentiviral

   Promoter

   CMV promoter and Human U6

   Available Since

   Dec. 23, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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6. ADRBK2 gRNA (BRDN0001487158)

   Plasmid

   #77943

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human ADRBK2

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   ADRBK2
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   hU6

   Available Since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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7. PX458_FOXM1_iso1_2

   Plasmid

   #135753

   Purpose

   Encodes gRNA for 3' target of human FOXM1_iso1

   Depositor

   Richard M. Myers

   Article

   Savic et al Genome Res. 2015 Sep 9.

   Insert

   FOXM1_iso1 gRNA (FOXM1 Human)
   

   Use

   CRISPR

   Promoter

   U6

   Available Since

   Jan. 27, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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8. PX458_FOXM1_iso1_1

   Plasmid

   #135752

   Purpose

   Encodes gRNA for 3' target of human FOXM1_iso1

   Depositor

   Richard M. Myers

   Article

   Savic et al Genome Res. 2015 Sep 9.

   Insert

   FOXM1_iso1 gRNA (FOXM1 Human)
   

   Use

   CRISPR

   Promoter

   U6

   Available Since

   Jan. 24, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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9. TRIM27 gRNA (BRDN0001149189)

   Plasmid

   #77514

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human TRIM27

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   TRIM27 (TRIM27 Human)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   hU6

   Available Since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

10. TRIM27 gRNA (BRDN0001149307)

    Plasmid

    #77515

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human TRIM27

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    TRIM27 (TRIM27 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

11. ROCK2 gRNA (BRDN0001145177)

    Plasmid

    #76351

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human ROCK2

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    ROCK2 (ROCK2 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

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12. pMS4 (Empty insertion vector with SEC)

    Plasmid

    #154837

    Purpose

    Vector that can be modified to add gene(s) of interest to C. elegans ChrII:8420157 site via CRISPR with SEC selection

    Depositor

    Patrick Phillips

    Article

    Stevenson et al G3 (Bethesda). 2020 Aug 19. pii: g3.120.

    Insert

    SEC
    

    Use

    CRISPR and Cre/Lox

    Expression

    Worm

    Mutation

    sqt-1(e1350)

    Available Since

    Aug. 6, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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13. pJZC101

    Plasmid

    #62335

    Purpose

    sgRNA (no RNA aptamer addition) with COM-VP64 effector for mammalian cells

    Depositor

    Wendell Lim, Stanley Qi

    Article

    Zalatan et al Cell. 2014 Dec 18. pii: S0092-8674(14)01

    Inserts

    sgRNA
    COM-VP64
    

    Use

    Lentiviral

    Tags

    VP64

    Expression

    Mammalian

    Mutation

    Targets Tet3G, sequence: GTACGTTCTCTATCACTGATA

    Promoter

    CMV and U6

    Available Since

    April 2, 2015

    Availability

    Academic Institutions and Nonprofits only

    

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14. PAK4 gRNA (BRDN0001147629)

    Plasmid

    #77573

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human PAK4

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    PAK4 (PAK4 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

15. non-targeting control gRNA (BRDN0001147797)

    Plasmid

    #80204

    Purpose

    3rd generation lentiviral gRNA plasmid, non-targeting control gRNA

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    Non-targeting control gRNA
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    Aug. 30, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

16. ZAP70 gRNA (BRDN0001148252)

    Plasmid

    #77955

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human ZAP70

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    ZAP70 (ZAP70 )
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. non-targeting control gRNA (BRDN0001146436)

    Plasmid

    #80221

    Purpose

    3rd generation lentiviral gRNA plasmid, non-targeting control gRNA

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    Non-targeting control gRNA
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    Aug. 30, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. non-targeting control gRNA (BRDN0001146476)

    Plasmid

    #80194

    Purpose

    3rd generation lentiviral gRNA plasmid, non-targeting control gRNA

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    Non-targeting control gRNA
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    Aug. 30, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. pLCKO_PSMB2_sgRNA_1

    Plasmid

    #74184

    Purpose

    lentiviral vector expressing sgRNA targeting PSMB2

    Depositor

    Jason Moffat

    Article

    Hart et al Cell. 2015 Dec 3;163(6):1515-26. doi: 10

    Insert

    PSMB2 sgRNA
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    U6 Promoter

    Available Since

    March 30, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. ULK2 gRNA (BRDN0001147288)

    Plasmid

    #77262

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human ULK2

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    ULK2 (ULK2 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge