167,825 results

1. mApple-M1 Spastin

   Plasmid

   #134461

   Purpose

   M1 Spastin expression

   Depositor

   Jennifer Lippincott-Schwartz

   Article

   Chang et al J Cell Biol. 2019 Aug 5;218(8):2583-2599

   Insert

   M1 Spastin (SPAST Human)
   

   Expression

   Mammalian

   Mutation

   Met to Ala change at amino acid 87

   Promoter

   CMV

   Available Since

   Nov. 25, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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2. PB-TA-ERN-SETD5

   Plasmid

   #236616

   Purpose

   Expresses human SETD5 in mammalian cells

   Depositor

   Tadashi Nakagawa

   Article

   Sashiyama et al iScience. 2025 May 19;28(6):112699. doi:

   Insert

   SETD5 (SETD5 Human)
   

   Use

   Piggybac transposon

   Expression

   Mammalian

   Available Since

   Sept. 18, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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3. SM283_EF1A-dEnAsCas12a-VPR-T2A-EGFP

   Plasmid

   #244218

   Purpose

   Mammalian expression of dEnAsCas12a-VPR with EGFP selectable marker

   Depositor

   Tim Reddy

   Insert

   dEnAsCas12a-VPR
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Mutation

   dEnAsCas12a: E174R, S542R, K548R, and D908A

   Available Since

   Sept. 16, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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4. SM265_EF1A-dHyperLbCas12a-KRAB-T2A-EGFP

   Plasmid

   #244204

   Purpose

   Mammalian expression of dHyperLbCas12a-KRAB with EGFP selectable marker

   Depositor

   Tim Reddy

   Insert

   dHyperLbCas12a-KRAB
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Mutation

   dHyperLbCas12a: D156R, D235R, E292R, E350R, and D…

   Available Since

   Sept. 16, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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5. SM284_EF1A-dEnAsCas12a-VPR-T2A-BlastR

   Plasmid

   #244219

   Purpose

   Mammalian expression of dEnAsCas12a-VPR with Blasticidin resistance selectable marker

   Depositor

   Tim Reddy

   Insert

   dEnAsCas12a-VPR
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Mutation

   dEnAsCas12a: E174R, S542R, K548R, and D908A

   Available Since

   Sept. 16, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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6. pcDNA 3.3 N-MYC FLNA

   Plasmid

   #227876

   Purpose

   Used for transfection of cells for expression of C-MYC FLNA

   Depositor

   Sheng-cai Lin

   Article

   Li et al Cell Res. 2024 Jun 19. doi: 10.1038/s414

   Insert

   FLNA (Flna Mouse)
   

   Tags

   MYC

   Expression

   Mammalian

   Available Since

   June 27, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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7. pDL0_158

   Plasmid

   #210779

   Purpose

   PUSCT_Drosophila melanogaster Gypsy-insulator sequence

   Depositor

   Dmitri Nusinow

   Article

   Lee et al bioRxiv 2025.06.20.660755

   Insert

   Gypsy insulator
   

   Use

   Synthetic Biology

   Expression

   Plant

   Available Since

   June 25, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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8. pNeuroD1-ERT2CreERT2

   Plasmid

   #237402

   Purpose

   Tamoxifen-dependent expression of ERT2CreERT2 in NeuroD1-positive cells

   Depositor

   Yusuke Kishi

   Article

   Sakai et al Development. 2025 Jul 1;152(13):dev20456

   Insert

   ERT2CreERT2
   

   Expression

   Mammalian

   Available Since

   June 11, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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9. pTW2157

   Plasmid

   #236581

   Purpose

   ISYmu1 CHLl1 gRNA7 TRV2 Architecture_B

   Depositor

   Steven Jacobsen

   Article

   Weiss et al Nat Plants. 2025 Apr 22. doi: 10.1038/s4

   Insert

   ISYmu1 TnpB
   

   Expression

   Plant

   Available Since

   May 2, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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10. pTW2156

    Plasmid

    #236580

    Purpose

    ISYmu1 CHLl1 gRNA6 TRV2 Architecture_B

    Depositor

    Steven Jacobsen

    Article

    Weiss et al Nat Plants. 2025 Apr 22. doi: 10.1038/s4

    Insert

    ISYmu1 TnpB
    

    Expression

    Plant

    Available Since

    May 2, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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11. pTW2153

    Plasmid

    #236577

    Purpose

    ISYmu1 CHLl1 gRNA3 TRV2 Architecture_B

    Depositor

    Steven Jacobsen

    Article

    Weiss et al Nat Plants. 2025 Apr 22. doi: 10.1038/s4

    Insert

    ISYmu1 TnpB
    

    Expression

    Plant

    Available Since

    May 2, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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12. pTW2159

    Plasmid

    #236582

    Purpose

    ISYmu1 CHLl1 gRNA9 TRV2 Architecture_B

    Depositor

    Steven Jacobsen

    Article

    Weiss et al Nat Plants. 2025 Apr 22. doi: 10.1038/s4

    Insert

    ISYmu1 TnpB
    

    Expression

    Plant

    Available Since

    May 1, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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13. pTW2155

    Plasmid

    #236579

    Purpose

    ISYmu1 CHLl1 gRNA5 TRV2 Architecture_B

    Depositor

    Steven Jacobsen

    Article

    Weiss et al Nat Plants. 2025 Apr 22. doi: 10.1038/s4

    Insert

    ISYmu1 TnpB
    

    Expression

    Plant

    Available Since

    May 1, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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14. FIRESFLIP-PBCS-E670

    Plasmid

    #228701

    Purpose

    Sensor cassette FIRE2, sensor in backwards orientation, FIRE fluorescent ratiometric sensor

    Depositor

    Carolyn Sangokoya

    Article

    Sangokoya et al Cell Rep Methods. 2025 Jan 11:100960. do

    Insert

    FIRE2 SENSOR
    

    Use

    Synthetic Biology and Unspecified

    Expression

    Mammalian

    Promoter

    EF1-alpha

    Available Since

    Jan. 28, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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15. pET-28a(+)-T7-OmpA-MNaseB-6xHis

    Plasmid

    #214809

    Purpose

    Expression of 6xhis-tagged micrococcal nuclease B (MNaseB)

    Depositor

    Peter Sarin

    Article

    Gregorova et al J Biol Chem. 2024 Nov 27;301(1):108020.

    Insert

    OmpA-Micrococcal nuclease B
    

    Tags

    6xhis

    Expression

    Bacterial

    Promoter

    T7 promoter

    Available Since

    Nov. 27, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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16. pNLF1-C_CSNK2A2:1-350

    Plasmid

    #211081

    Purpose

    Mammalian expression of full-length human CSNK2A2. C-terminal NanoLuc luciferase tag.

    Depositor

    Cheryl Arrowsmith

    Article

    Ackloo et al J Med Chem. 2025 Jan 23;68(2):1092-1112.

    Insert

    CSNK2A2:M1-R350 (CSNK2A2 Human)
    

    Tags

    NanoLuc luciferase

    Expression

    Mammalian

    Mutation

    wild type

    Promoter

    CMV

    Available Since

    March 19, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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17. pCAGGS-3xFLAG-bIV spectrin (repeats 13-15)

    Plasmid

    #213728

    Purpose

    Mammalian cell expression vector for overexpression of bIV spectrin (repeats 13-15) in NIH/3T3 cells.

    Depositor

    Chaolin Zhang

    Article

    Jacko et al Neuron. 2018 Feb 21;97(4):853-868.e6. do

    Insert

    bIV spectrin (repeats 13-15) (Sptbn4 Mouse)
    

    Expression

    Mammalian

    Available Since

    March 4, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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18. pCMV-SlugCas9-P2A-puro

    Plasmid

    #214353

    Purpose

    Expresses SlugCas9 and puromycin resistance genes

    Depositor

    Yongming Wang

    Article

    Qi et al Nat Chem Biol. 2023 Dec 5. doi: 10.1038/

    Insert

    SlugCas9 and puromycin resistance genes
    

    Expression

    Mammalian

    Available Since

    Feb. 29, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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19. pfa6a mScarlet-FKBP::KANMX

    Plasmid

    #185905

    Purpose

    Plasmid for cloning mScarlet fused to FKBP into yeast.

    Depositor

    Matthew Good

    Article

    Garabedian et al Nat Chem Biol. 2021 Sep;17(9):998-1007.

    Insert

    mScarlet-FKBP
    

    Tags

    mScarlet fused to FKBP

    Expression

    Yeast

    Promoter

    SP6

    Available Since

    Sept. 26, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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20. pICH47811-pAtAct2::Cas9-nls::tSlATPase

    Plasmid

    #160221

    Purpose

    Cas9-nuclear localization, pACT2 promoter, SlATPase terminator transcriptional unit, inserted at the MoClo toolkit level 1 acceptor position 2 reverse

    Depositor

    Matias Kirst

    Article

    Triozzi et al Tree Physiol. 2021 May 7. pii: 6270869.

    Insert

    pAtACT2::Cas9-nls::tSlATPase
    

    Use

    Synthetic Biology; Moclo toolkit level 1 acceptor…

    Expression

    Plant

    Available Since

    Aug. 15, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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21. PU6::unc-119_sgRNA

    Plasmid

    #46169

    Purpose

    unc-119 targeting sgRNA

    Depositor

    John Calarco

    Article

    Friedland et al Nat Methods. 2013 Jun 30. doi: 10.1038/n

    Insert

    unc-119 targeting sgRNA (unc-119 Synthetic)
    

    Use

    CRISPR

    Promoter

    C. elegans U6 snRNA pol III promoter

    Available Since

    July 1, 2013

    Availability

    Academic Institutions and Nonprofits only

    

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22. pAAV-syn-Flpo (AAV Retrograde)

    Viral Prep

    #174378-AAVrg

    Purpose

    Ready-to-use AAV Retrograde particles produced from pAAV-syn-Flpo (#174378). In addition to the viral particles, you will also receive purified pAAV-syn-Flpo plasmid DNA. Syn-driven expression of the recombinase FLPo. These AAV were produced with a retrograde serotype, which permits retrograde access to projection neurons. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Ian Wickersham

    Article

    Jin et al Nat Neurosci. 2024 Jan 11. doi: 10.1038/

    Available Since

    Oct. 21, 2024

    Availability

    Academic Institutions and Nonprofits only

23. mGreenLantern

    Plasmid

    #197928

    Purpose

    Monomer expression vector

    Depositor

    Salvatore Chiantia

    Article

    Petrich et al PLoS One. 2023 Aug 3;18(8):e0285486. doi

    Insert

    mGreenLantern
    

    Expression

    Mammalian

    Mutation

    none

    Available Since

    April 19, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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24. pMaRSC

    Plasmid

    #89189

    Purpose

    The pMaRS plasmid is the same construct as pMaRSL274G, but contains a T2A-Mcherry sequence appended to the C-terminal of L274GMmMetRS.

    Depositor

    David Tirrell

    Article

    Mahdavi et al J Am Chem Soc. 2016 Apr 6;138(13):4278-8

    Insert

    Flag-L274G-T2A-mCherry (Mars1 Mouse)
    

    Available Since

    April 10, 2017

    Availability

    Academic Institutions and Nonprofits only

    

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25. C1(1-29)-TurboID-V5_pLX304

    Plasmid

    #107175

    Purpose

    expresses V5-tagged TurboID on the mammalian ER membrane, lentiviral vector

    Depositor

    Alice Ting

    Article

    Branon et al Nat Biotechnol. 2018 Aug 20. pii: nbt.42

    Insert

    TurboID (BirA mutant)
    

    Use

    Lentiviral

    Mutation

    Q65P, I87V, R118S, E140K, Q141R, S150G, L151P, V1…

    Available Since

    May 4, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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26. pLVX-2xFLAG-2xSTREP-CCND3-IRES-mCherry

    Plasmid

    #172620

    Purpose

    Lentiviral bicistronic vector for the constitutive co-expression of 2xFLAG-2xSTREP-tagged cyclin D3 and mCherry in mammalian cells

    Depositor

    Michele Pagano

    Article

    Simoneschi et al Nature. 2021 Apr;592(7856):789-793. doi:

    Insert

    CCND3 (CCND3 Human)
    

    Use

    Lentiviral

    Tags

    2xFLAG-2xSTREP

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    Aug. 20, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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27. [#GS24 -LV] Syn1-GFP-OMP25

    Plasmid

    #233566

    Purpose

    Lentiviral construct of mitochondrial localized GFP to be expressed in the donor cells under the Synapsin1 promotor

    Depositor

    Simon Grelet

    Article

    Hoover et al Nature. 2025 Jun 25. doi: 10.1038/s41586

    Insert

    eGFP (eGFP Synthetic, Aequorea victoria)
    

    Use

    Lentiviral and Synthetic Biology

    Expression

    Mammalian

    Available Since

    June 5, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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28. pCAG_smFP HA

    Plasmid

    #59759

    Purpose

    encodes multiple copies of an epitope tag HA

    Depositor

    Loren Looger

    Article

    Viswanathan et al Nat Methods. 2015 Jun;12(6):568-76. doi:

    Insert

    smFP _HA
    

    Expression

    Mammalian

    Promoter

    CAG

    Available Since

    Oct. 21, 2014

    Availability

    Academic Institutions and Nonprofits only

    

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29. pSC189

    Plasmid

    #32114

    Depositor

    Eric Rubin

    Article

    Chiang et al Gene. 2002 Aug 21;296(1-2):179-85.

    Type

    Empty backbone

    Use

    Transposon delivery vector

    Tags

    3x FLAG

    Available Since

    Oct. 14, 2011

    Availability

    Academic Institutions and Nonprofits only

    

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30. Artichoke

    Plasmid

    #73320

    Purpose

    Artichoke is a protein degradation reporter plasmid in a lentiviral backbone (SFFV.BsmBIClonesite.17AARigidLinker-EGFP.IRES.mCherry.cppt.EF1a.PuroR)

    Depositor

    Benjamin Ebert

    Article

    Slabicki et al Nature. 2020 Sep;585(7824):293-297. doi:

    Type

    Empty backbone

    Use

    Lentiviral

    Tags

    EGFP

    Expression

    Mammalian

    Promoter

    SFFV and EF1a

    Available Since

    July 5, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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31. pLentiCRISPR-E

    Plasmid

    #78852

    Purpose

    Introduce sgRNA into a lentiviral vector (LentiCRISPR V2) which contains eSpCas9 and puromycin cassette

    Depositor

    Phillip Abbosh

    Article

    Sikder et al Mol Cancer Res. 2020 Dec 3. pii: 1541-77

    Type

    Empty backbone

    Use

    CRISPR and Lentiviral

    Tags

    Cas9-P2A-Puro

    Expression

    Mammalian

    Available Since

    June 29, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

32. pcDNA3-mNeptune2.5

    Plasmid

    #51310

    Purpose

    Expresses far-red fluorescent protein mNeptune2.5 in mammalian cells

    Depositor

    Michael Lin

    Article

    Chu et al Nat Methods. 2014 Mar 16. doi: 10.1038/n

    Insert

    mNeptune2.5
    

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    April 8, 2014

    Availability

    Academic Institutions and Nonprofits only

    

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33. pBMN BFP-Parkin

    Plasmid

    #186221

    Purpose

    For expression of Parkin tagged with BFP

    Depositor

    Michael Lazarou

    Article

    Nguyen et al Mol Cell. 2023 May 18;83(10):1693-1709.e

    Insert

    Parkin (PRKN Human)
    

    Use

    Retroviral

    Tags

    BFP

    Expression

    Mammalian

    Available Since

    May 23, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

34. pcDNA3.1-FLAG-Claspin

    Plasmid

    #12659

    Depositor

    Michele Pagano

    Article

    Peschiaroli et al Mol Cell. 2006 Aug 4. 23(3):319-29.

    Insert

    Claspin (CLSPN Human)
    

    Tags

    Flag

    Expression

    Mammalian

    Available Since

    May 16, 2007

    Availability

    Academic Institutions and Nonprofits only

35. pDDGFP_LEU2D

    Plasmid

    #58352

    Purpose

    Used for expressing recombinant proteins as a C terminal GFP-His tagged constuct in S.cerevisiae

    Depositor

    Simon Newstead

    Article

    Parker et al Protein Sci. 2014 Jun 20. doi: 10.1002/p

    Type

    Empty backbone

    Tags

    GFP-His

    Expression

    Yeast

    Promoter

    GAL1

    Available Since

    Aug. 29, 2014

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

36. dg263_pENTR_ChrimsonCel

    Plasmid

    #66101

    Purpose

    Entry clone containing Chrimson coding sequence (without stop codon), codon optimized for C. elegans, with synthetic introns, flanked by attL1 and attL2

    Depositor

    Dominique Glauser

    Article

    Schild et al Genetics. 2015 May 28. pii: genetics.115

    Insert

    Chrimson
    

    Use

    Gateway

    Available Since

    July 28, 2015

    Availability

    Academic Institutions and Nonprofits only

    

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37. pcDNA-dCas9-VP64

    Plasmid

    #47107

    Purpose

    Expresses inactivated S. pyogenes dCas9 (D10A, H840A) fused to VP64 transactivator domain in mammalian cells

    Depositor

    Charles Gersbach

    Article

    Perez-Pinera et al Nat Methods. 2013 Jul 25. doi: 10.1038/n

    Insert

    dCas9-VP64
    

    Use

    CRISPR

    Tags

    Flag, HA, SV40 NLS, and VP64

    Expression

    Mammalian

    Mutation

    D10A, H840A (catalytically inactive)

    Promoter

    CMV

    Available Since

    Nov. 14, 2013

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

38. pAAV-syn-FLP-FRT-iGluSnFR4f-NGR-WPRE

    Plasmid

    #234454

    Purpose

    AAV-mediated expression of glutamate sensor with improved sensitivity and fast deactivation kinetics (4f = fast); NGR vector matches or outperforms PDGFR in all conditions tested.

    Depositor

    GENIE Project

    Article

    Aggarwal et al bioRxiv 2025.03.20.643984

    Insert

    iGluSnFR4f-NGR
    

    Use

    AAV; Flp/frt

    Tags

    IgK chain and Myc epi tag-NGR GPI anchor

    Expression

    Mammalian

    Promoter

    Synapsin

    Available Since

    March 20, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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39. pAAV.CAG.Flex.GCaMP6m.WPRE.SV40 (AAV9)

    Viral Prep

    #100839-AAV9

    Purpose

    Ready-to-use AAV9 particles produced from pAAV.CAG.Flex.GCaMP6m.WPRE.SV40 (#100839). In addition to the viral particles, you will also receive purified pAAV.CAG.Flex.GCaMP6m.WPRE.SV40 plasmid DNA. CAG-driven, Cre-dependent GCaMP6m calcium sensor. These AAV preparations are suitable purity for injection into animals.

    Depositor

    GENIE Project, Douglas Kim

    Article

    Chen et al Nature. 2013 Jul 18;499(7458):295-300. d

    Promoter

    CAG

    Available Since

    May 14, 2018

    Availability

    Academic Institutions and Nonprofits only

40. pGL3 1kb prom. CD274

    Plasmid

    #107002

    Purpose

    Modified Luciferase expression vector

    Depositor

    Julian Downward

    Article

    Coelho et al Immunity. 2017 Dec 19;47(6):1083-1099.e6

    Insert

    CD274 (CD274 Human)
    

    Use

    Luciferase

    Expression

    Mammalian

    Available Since

    March 23, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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