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Enter a sequence to perform a BLAST-based search of Addgene plasmid sequence databases.

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We narrowed to 1,416 results for: TIR

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Showing: 41 - 60 of 1416 results

  1. LentiRCas9-Lambda2

    Plasmid
    #104184
    Purpose
    Lentiviral transfer vector that carries U6-driven non-targeting sgRNA using a modified scaffold (Chen et al. Cell 2013) and CMV-driven PIN-dCas9. Derived from LentiCRISPR v2 (Zhang lab)
    Depositor
    Eugene Yeo
    Article
    Batra et al Cell. 2017 Aug 24;170(5):899-912.e10. do
    Insert
    U6-sgRNA, EFS-PIN-dCas9
    Use
    CRISPR and Lentiviral
    Available Since
    April 13, 2018
    Availability
    Academic Institutions and Nonprofits only
    104184-plasmid-map-sequence-id-201745

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  5. TIRAP-TAP_IRES_GFP

    Plasmid
    #52740
    Purpose
    Retroviral vector expresses hTIRAP-3xHA and a target site for the biotin ligase BirA upstream of IRES and GFP
    Depositor
    Jonathan Kagan
    Article
    Bonham et al Cell. 2014 Feb 13;156(4):705-16. doi: 10
    Insert
    Toll/IL-1 Receptor adaptor protein (TIRAP Human)
    Use
    Retroviral
    Tags
    3x HA, 3x TEV, and BirA target site
    Expression
    Mammalian
    Available Since
    July 2, 2014
    Availability
    Academic Institutions and Nonprofits only

  6. pHRSV_CHARMS-2xTIR

    Plasmid
    #233930
    Purpose
    Mammalian expression of Chimeric Higher-Order Assemblies for Receptor Mediated Signaling (CHARMS) variant: CHARMS-2xTIR which contain a tandem dimer of TIR domains
    Depositor
    Marcus Taylor
    Article
    Lichtenstein et al bioRxiv 2024.05.08.593169
    Insert
    CHARMS-2xTIR
    Use
    Lentiviral
    Tags
    mEGFP
    Expression
    Mammalian
    Promoter
    SV40
    Available Since
    Aug. 28, 2025
    Availability
    Academic Institutions and Nonprofits only
    233930-plasmid-map-sequence-id-484962

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  7. pAd5Rep2entire-ATGf

    Plasmid
    #237878
    Purpose
    AAV packaging plasmid: This platform plasmid provides adenoviral helper functions and the AAV2 rep gene.
    Depositor
    Ascend Advanced Therapies, Florian Sonntag
    Insert
    rep2 and E2A, E4, L4-22K/33K, VA RNA
    Use
    AAV
    Available Since
    June 12, 2025
    Availability
    Academic Institutions and Nonprofits only
    237878-plasmid-map-sequence-id-475994

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  13. PLC-TIR-GFP

    Plasmid
    #52736
    Purpose
    Retroviral vector expresses the lipid binding domain of PLCd1 fused to the TIR of hTIRAP and GFP. Also contains IRES-hCD2 as selectable marker
    Depositor
    Jonathan Kagan
    Article
    Bonham et al Cell. 2014 Feb 13;156(4):705-16. doi: 10
    Insert
    Toll/IL-1 Receptor adaptor protein (TIRAP Human)
    Use
    Retroviral
    Tags
    GFP and PLCd1 Lipid binding
    Expression
    Mammalian
    Mutation
    Deleted amino acids 1-85
    Available Since
    June 18, 2014
    Availability
    Academic Institutions and Nonprofits only

  14. SLP2a-TIR-GFP

    Plasmid
    #52738
    Purpose
    Retroviral vector expresses the lipid binding domain of SLP2a fused to the TIR of hTIRAP and GFP. Also contains IRES-hCD2 as selectable marker
    Depositor
    Jonathan Kagan
    Article
    Bonham et al Cell. 2014 Feb 13;156(4):705-16. doi: 10
    Insert
    Toll/IL-1 Receptor adaptor protein (TIRAP Human)
    Use
    Retroviral
    Tags
    C2A domain of Murine SLP2a and GFP
    Expression
    Mammalian
    Mutation
    Deleted amino acids 1-85
    Available Since
    June 19, 2014
    Availability
    Academic Institutions and Nonprofits only
Showing: 41 - 60 of 1416 results