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Plasmid#184541PurposeAAV packaging plasmid, expressing Rep2 and AAV-MG1.2 capsidDepositorInsertAAV-MG1.2 capsid
UseAAV; Helper vector for packagingTagsExpressionMutationchanges on AAV9 capsid: K449R, Q588T; insertion o…PromoterAvailable sinceJuly 22, 2022AvailabilityAcademic Institutions and Nonprofits only -
rAAV2/cMG
Plasmid#184539PurposeAAV packaging plasmid, expressing Rep2 and AAV-cMG capsidDepositorInsertAAV-cMG capsid
UseAAV; Helper vector for packagingTagsExpressionMutationchanges on AAV9 capsid: K449R, A589D; insertion o…PromoterAvailable sinceJuly 22, 2022AvailabilityAcademic Institutions and Nonprofits only -
rAAV2/MG1.1
Plasmid#184540PurposeAAV packaging plasmid, expressing Rep2 and AAV-MG1.1 capsidDepositorInsertAAV-MG1.1 capsid
UseAAV; Helper vector for packagingTagsExpressionMutationchanges on AAV9 capsid: K449R, A587L, Q588M; inse…PromoterAvailable sinceJuly 22, 2022AvailabilityAcademic Institutions and Nonprofits only -
rAAV2/cMG.WPP
Plasmid#184542PurposeAAV packaging plasmid, expressing Rep2 and AAV-cMG.WPP capsidDepositorInsertAAV-cMG.WPP capsid
UseAAV; Helper vector for packagingTagsExpressionMutationchanges on AAV9 capsid: K449R; insertion of WPPKT…PromoterAvailable sinceJuly 22, 2022AvailabilityAcademic Institutions and Nonprofits only -
rAAV2/cMG.QRP
Plasmid#184543PurposeAAV packaging plasmid, expressing Rep2 and AAV-cMG.QRP capsidDepositorInsertAAV-cMG.QRP capsid
UseAAV; Helper vector for packagingTagsExpressionMutationchanges on AAV9 capsid: K449R; insertion of QRPPR…PromoterAvailable sinceJuly 22, 2022AvailabilityAcademic Institutions and Nonprofits only -
pJEP210-AAV-0.4CaMKII P-MCS-pA
Plasmid#63084PurposeAAV2 vector backbone containing a 0.4CaMKIIa promoter followed by a multiple cloning site(MCS) followed by a poly-Adenylation Signal (pA)DepositorTypeEmpty backboneUseAAVTagsExpressionMutationPromoter0.4αCaMKIIAvailable sinceMarch 16, 2022AvailabilityAcademic Institutions and Nonprofits only -
014LP-pAAV-ANF-657- Cre-pA
Plasmid#120279PurposeAAV vector for Atrial specific Cre recombinase expressionDepositorInsertCre
UseAAVTagsCREExpressionMutationPromoterANF promoterAvailable sinceFeb. 5, 2019AvailabilityAcademic Institutions and Nonprofits only -
AAV-SYN-NLS-SaCas9-NLS-3xHA-bGHpA-U6-BsaI-sgRNA
Plasmid#218710PurposeAAV vector plasmid expressing Cas9 from Staphylococcus aureus (SaCas9) under the human synapsin (SYN) promoter and its sgRNA under the U6 promoterDepositorInsertshSaCas9
Chimeric guide for SaCas9
UseAAV and CRISPRTags3xHA and NLSExpressionMammalianMutationPromoterAvailable sinceMay 13, 2024AvailabilityAcademic Institutions and Nonprofits only -
AAV-SYN-mCherry-oPRE
Plasmid#218682PurposeAAV vector plasmid expressing mCherry under the human synapsin (SYN) promoter. It also contains an optimised and truncated version of WPRE as a regulatory element.DepositorInsertmCherry
UseAAVTagsExpressionMammalianMutationPromoterAvailable sinceOct. 2, 2024AvailabilityAcademic Institutions and Nonprofits only -
pZFN-AAVS1_ELD
Plasmid#159297PurposeZFN (left) targeting the AAVS1 locus with obligate heterodimer FokIDepositorInsertZFN targeting the AAVS1 locus
UseTagsExpressionMammalianMutationPromoterCMV promoterAvailable sinceSept. 23, 2020AvailabilityAcademic Institutions and Nonprofits only -
AAV-F in pAR-9
Plasmid#166921PurposeAAV rep/cap plasmid. Capsid is mouse brain tropic AAV-FDepositorInsertREP/CAP
UseAAVTagsExpressionMutationPromoterAvailable sinceApril 7, 2021AvailabilityAcademic Institutions and Nonprofits only -
pAAV2-CMV-GFP-BGHpA
Plasmid#190239PurposeExpresses EGFP in mammalian cellsDepositorInsertEGFP
UseAAVTagsExpressionMammalianMutationPromoterAvailable sinceNov. 10, 2022AvailabilityAcademic Institutions and Nonprofits only -
pAAV2-SYN-GFP-BGHpA
Plasmid#190229PurposeExpresses EGFP in neuronal cellsDepositorInsertEGFP
UseAAVTagsExpressionMammalianMutationPromoterAvailable sinceNov. 4, 2022AvailabilityAcademic Institutions and Nonprofits only -
pAAV-hSyn-fDIO-mCherry-WPREpA
Plasmid#177328PurposeControl vector for Flp-dependent DREADD constructsDepositorInsertmCherry
UseAAV; Flp-frtTagsExpressionMammalianMutationPromoterHuman Synapsin-1Available sinceDec. 6, 2021AvailabilityAcademic Institutions and Nonprofits only -
pOttc1494 - pAAV CaMKII SERCaMP-No Tag
Plasmid#192601PurposeAn AAV packaging vector that expresses SERCaMP under control of the CaMKII promoter.DepositorInsertSERCaMP
UseAAVTagsExpressionMutationPromoterCaMKIIAvailable sinceJan. 6, 2023AvailabilityAcademic Institutions and Nonprofits only -
pAAV-EF1a-Cre
Plasmid#55636PurposeExpresses Cre in Mammalian CellsDepositorHas ServiceAAV RetrogradeInsertCre
UseAAV and Cre/LoxTagsExpressionMammalianMutationPromoterEf1aAvailable sinceJuly 22, 2014AvailabilityAcademic Institutions and Nonprofits only -
pAAV-EF1a-vCre
Plasmid#55638PurposeEF1a-driven expression of VCre in Mammalian CellsDepositorHas ServiceAAV Retrograde and AAV8InsertvCre
UseAAVTagsExpressionMammalianMutationPromoterEf1aAvailable sinceJuly 10, 2014AvailabilityAcademic Institutions and Nonprofits only -
pAAV-EF1a-sCre
Plasmid#55635PurposeExpresses sCre in Mammalian CellsDepositorInsertCre
UseAAV and Cre/LoxTagsExpressionMammalianMutationPromoterEF1alphaAvailable sinceJuly 10, 2014AvailabilityAcademic Institutions and Nonprofits only -
AAV-hSyn-Axon-jGCaMP8f
Plasmid#192615PurposeAAV transfer plasmid for neuronal expression of axon-targeted jGCaMP8f.DepositorInsertAxon-jGCaMP8f
UseAAVTags6xHisExpressionMammalianMutationPromoterAvailable sinceDec. 19, 2022AvailabilityAcademic Institutions and Nonprofits only -
pAAV-CAG-RiboL1-jGCaMP8s
Plasmid#192611PurposeAAV transfer plasmid for CAG mediated expression of soma-targeted (RiboL1) jGCaMP8s.DepositorInsertRiboL1-jGCaMP8s
UseAAVTags6xHisExpressionMammalianMutationPromoterAvailable sinceDec. 19, 2022AvailabilityAcademic Institutions and Nonprofits only -
AAV-hSyn-jRex-GECO
Plasmid#169259PurposeAAV transfer plasmid for neuronal expression of jRex-GECO.DepositorInsertJRex-GECO
UseAAVTagsExpressionMammalianMutationPromoterhSynAvailable sinceMay 18, 2021AvailabilityAcademic Institutions and Nonprofits only -
pAAV-CAG-RiboL1-jGCaMP8f
Plasmid#192612PurposeAAV transfer plasmid for CAG mediated expression of soma-targeted (RiboL1) jGCaMP8f.DepositorInsertRiboL1-jGCaMP8f
UseAAVTags6xHisExpressionMammalianMutationPromoterAvailable sinceDec. 19, 2022AvailabilityAcademic Institutions and Nonprofits only -
pAAV-CAG-RiboL1-jGCaMP8m
Plasmid#192613PurposeAAV transfer plasmid for CAG mediated expression of soma-targeted (RiboL1) jGCaMP8m.DepositorInsertRiboL1-jGCaMP8m
UseAAVTags6xHisExpressionMammalianMutationPromoterAvailable sinceDec. 19, 2022AvailabilityAcademic Institutions and Nonprofits only -
AAV-GfaABC1D-DreO-4x6T
Plasmid#196413PurposeAstrocytic expression of Dre recombinase in AAV; astrocyte specificity enhanced with 4x6T miRNA targeting cassetteDepositorInsertDreO
UseAAV; Astrocyte-selectiveTagsExpressionMammalianMutationPromoterCAG and GfaABC1DAvailable sinceFeb. 21, 2023AvailabilityAcademic Institutions and Nonprofits only -
AAV-CMV-H2B-FusionRed
Plasmid#164430PurposeAAV plasmid expressing nuclear-localized FusionRed fluorophoreDepositorInsertH2B-FusionRed
UseAAVTagsH2BExpressionMammalianMutationPromoterCMVAvailable sinceMay 7, 2022AvailabilityAcademic Institutions and Nonprofits only -
AAV-hSyn-Ribo-jGCaMP8s
Plasmid#167572PurposeDEPRECATED: Please see Addgene item #169247 for an improved version of this plasmid. AAV transfer plasmid for neuronal expression of soma-targeted (RL-10, ribosomal tag) jGCaMP8s.DepositorHas ServiceAAV1InsertRibo-GCaMP8s
UseAAVTags6xHisExpressionMammalianMutationPromoterhSynAvailable sinceJune 9, 2021AvailabilityAcademic Institutions and Nonprofits only -
AAV-hSyn-Ribo-jGCaMP8m
Plasmid#167574PurposeDEPRECATED: Please see Addgene item #169248 for an improved version of this plasmid. AAV transfer plasmid for neuronal expression of soma-targeted (RL-10, ribosomal tag) jGCaMP8m.DepositorHas ServiceAAV1InsertRibo-GCaMP8m
UseAAVTags6xHisExpressionMammalianMutationPromoterhSynAvailable sinceJune 9, 2021AvailabilityAcademic Institutions and Nonprofits only -
AAV-hSyn-Ribo-jGCaMP8f
Plasmid#167573PurposeDEPRECATED: Please see Addgene item #169249 (coming soon) for an improved version of this plasmid. AAV transfer plasmid for neuronal expression of soma-targeted (RL-10, ribosomal tag) jGCaMP8f.DepositorInsertRibo-GCaMP8f
UseAAVTags6xHisExpressionMammalianMutationPromoterhSynAvailable sinceJune 9, 2021AvailabilityAcademic Institutions and Nonprofits only -
pAAV-R-Creon shRNA[Control]
Plasmid#180775PurposeThis vector simultaneously expresses mCherry protein and shRNA in a Cre-dependent manner.DepositorTypeEmpty backboneUseAAV, Cre/Lox, and RNAiTagsExpressionMammalianMutationPromoterAvailable sinceMay 23, 2022AvailabilityAcademic Institutions and Nonprofits only -
pAAV-G-Creon shRNA[Control]
Plasmid#181824PurposeThis vector simultaneously expresses GFP protein and shRNA in a Cre-dependent manner.DepositorTypeEmpty backboneUseAAV and RNAiTagsExpressionMammalianMutationPromoterEF1a/U6Available sinceMay 20, 2022AvailabilityAcademic Institutions and Nonprofits only -
pOttc1501 - pscAAV CMV-IE hCDNF
Plasmid#188538PurposeAn AAV packaging vector that expresses hCDNF under control of the CMV-IE promoter.DepositorInserthCDNF (CDNF Human)
UseAAVTagsExpressionMutationPromoterCMV-IEAvailable sinceAug. 22, 2022AvailabilityAcademic Institutions and Nonprofits only -
pAAV-MP-84-spCas9-U6-gRNA-tlock
Plasmid#206936PurposeExpression of spCas9 endonuclease and gRNA in an AAV vector allowing packaging of viral genome smaller than 5 kb.DepositorInsertspCas9
UseAAVTagsSV40 NLSExpressionMammalianMutationPromoterMP-84Available sinceSept. 13, 2023AvailabilityAcademic Institutions and Nonprofits only -
pOttc438 - pAAV EF1a CRE ERT2 bGHpA
Plasmid#210415PurposeAAV viral vector packaging plasmid that expresses tamoxifen-regulated Cre recombinaseDepositorInsertCre-ERT2
UseAAVTagsExpressionMutationPromoterEF1aAvailable sinceJan. 2, 2024AvailabilityAcademic Institutions and Nonprofits only -
pAAV-CMV-iRFP713(V256C)-P2A-EGFP
Plasmid#198071PurposeThe AAV vector for iRFP713(V256C) and EGFPDepositorInsertiRFP713(V256C)
UseAAVTagsP2A-EGFPExpressionMutationV256C mutationPromoterCMVAvailable sinceAug. 7, 2023AvailabilityAcademic Institutions and Nonprofits only -
AAV-SYN-eGFP-oPRE
Plasmid#218681PurposeAAV vector plasmid expressing enhanced green fluorescent protein (eGFP) under the human synapsin (SYN) promoter. It also contains an optimised and truncated version of WPRE as a regulatory element.DepositorInserteGFP
UseAAVTagsExpressionMammalianMutationPromoterAvailable sinceMay 13, 2024AvailabilityAcademic Institutions and Nonprofits only -
AAV-GfaABC1D-Cre-4x6T
Plasmid#196410PurposeAstrocytic expression of Cre recombinase in AAV; astrocyte specificity enhanced with 4x6T miRNA targeting cassetteDepositorHas ServiceAAV5InsertCre
UseAAV; Astrocyte-selectiveTagsExpressionMammalianMutationPromoterCAG and GfaABC1DAvailable sinceFeb. 21, 2023AvailabilityAcademic Institutions and Nonprofits only -
AAV-GfaABC1D-ERCreER-4x6T
Plasmid#196411PurposeAstrocytic expression of ERT2-Cre-ERT2 recombinase in AAV; astrocyte specificity enhanced with 4x6T miRNA targeting cassetteDepositorInsertERT2-Cre-ERT2
UseAAV; Astrocyte-selectiveTagsExpressionMammalianMutationPromoterCAG and GfaABC1DAvailable sinceFeb. 21, 2023AvailabilityAcademic Institutions and Nonprofits only -
pAAV-hSyn-RiboL1-jGCaMP7c
Plasmid#192619PurposeAAV transfer plasmid for neuronal expression of soma-targeted (RiboL1) jGCaMP7c.DepositorInsertRiboL1-jGCaMP7c
UseAAVTags6xHisExpressionMammalianMutationPromoterAvailable sinceDec. 19, 2022AvailabilityAcademic Institutions and Nonprofits only -
AAV-GfaABC1D-iCreV-4x6T
Plasmid#196412PurposeAstrocytic expression of light-inducible iCreV recombinase in AAV; astrocyte specificity enhanced with 4x6T miRNA targeting cassetteDepositorInsertiCreV
UseAAV; Astrocyte-selectiveTagsExpressionMammalianMutationPromoterCAG and GfaABC1DAvailable sinceFeb. 21, 2023AvailabilityAcademic Institutions and Nonprofits only -
pEJS1089: mini-AAV.sgRNA.Nme2Cas9
Plasmid#159536PurposeDelivery of Nme2Cas9 and its sgRNA in a single AAV vector with overall packaging size of 4.4 KbDepositorInsertNme2Cas9 with single guide RNA cassette
UseAAV, CRISPR, and Mouse TargetingTagsNLSExpressionMammalianMutationPromoterU1aAvailable sinceOct. 13, 2020AvailabilityAcademic Institutions and Nonprofits only