78,292 results

1. pcDNA3.3_SARS2_omicron BA.2

   Plasmid

   #183700

   Purpose

   expressing SARS-CoV-2 BA.2 spike protein for pseudovirus production

   Depositor

   David Nemazee

   Article

   Dacon et al Science. 2022 Jul 12:eabq3773. doi: 10.1

   Insert

   Spike (BA.2) (S SARS-CoV-2)
   

   Use

   Lentiviral and Retroviral

   Expression

   Mammalian

   Mutation

   c-terminal 18 aa deletion

   Promoter

   CMV

   Available Since

   April 4, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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2. pCMV-PEmax-P2A-hMLH1dn

   Plasmid

   #174828

   Purpose

   Mammalian expression of SpCas9 PEmax prime editor with P2A-human MLH1dn (codon optimized)

   Depositor

   David Liu

   Article

   Chen et al Cell. 2021 Oct 28;184(22):5635-5652.e29.

   Insert

   PEmax-P2A-hMLH1dn
   

   Tags

   SV40 bpNLS and c-Myc NLS

   Expression

   Mammalian

   Mutation

   Detailed in manuscript; deletion of residues 754-…

   Promoter

   CMV

   Available Since

   Oct. 14, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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3. HA-FOXO3a WT

   Plasmid

   #1787

   Depositor

   Michael Greenberg

   Article

   Brunet et al Cell 1999 Mar 19;96(6):857-68.

   Insert

   FOXO3a (FOXO3 Human)
   

   Tags

   HA (YDVPDYASL)

   Expression

   Mammalian

   Available Since

   Dec. 7, 2005

   Availability

   Academic Institutions and Nonprofits only

   

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4. Tau (wt) -VC

   Plasmid

   #87369

   Purpose

   expresses hTau fused to the C-terminal part of Venus

   Depositor

   Tiago Outeiro

   Article

   Blum et al Hum Mol Genet. 2015 Jan 1;24(1):76-85. d

   Insert

   MAPT (MAPT Human)
   

   Tags

   c-terminal part of Venus

   Expression

   Mammalian

   Promoter

   CMV

   Available Since

   Oct. 20, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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5. pcDNA5/FRT/TO V5 HSPA8

   Plasmid

   #19514

   Depositor

   Harm Kampinga

   Article

   Hageman et al Cell Stress Chaperones. 2009 Jan;14(1):1

   Insert

   heat shock 70kDa protein 8 (HSPA8 Human)
   

   Tags

   V5

   Expression

   Mammalian

   Available Since

   Oct. 6, 2008

   Availability

   Academic Institutions and Nonprofits only

   

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6. GFP-PBRM1

   Plasmid

   #65387

   Purpose

   GFP-tagged BRD protein, which can be used to be expressed in mammalian cells.

   Depositor

   Kyle Miller

   Article

   Gong et al Genes Dev. 2015 Jan 15;29(2):197-211. do

   Insert

   PBRM1 (PBRM1 Human)
   

   Tags

   EmGFP and V5

   Expression

   Mammalian

   Mutation

   none

   Promoter

   CMV

   Available Since

   May 14, 2015

   Availability

   Academic Institutions and Nonprofits only

   

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7. mCherry-Moesin-C-14

   Plasmid

   #55103

   Purpose

   Localization: Cytoskeleton/Membrane, Excitation: 587, Emission: 610

   Depositor

   Michael Davidson

   Insert

   Moesin (MSN Human)
   

   Tags

   mCherry

   Expression

   Mammalian

   Promoter

   CMV

   Available Since

   Aug. 29, 2014

   Availability

   Academic Institutions and Nonprofits only

8. pC035 - dLwCas13a-msfGFP

   Plasmid

   #91925

   Purpose

   Expresses catalytically inactive LwCas13a for mammalian RNA targeting

   Depositor

   Feng Zhang

   Article

   Abudayyeh et al Nature. 2017 Oct 4. doi: 10.1038/nature2

   Insert

   dLwCas13a
   

   Use

   CRISPR

   Tags

   NLS-3xHA and NLS-msfGFP

   Expression

   Mammalian

   Mutation

   R488A and R1060A

   Promoter

   EF-1a

   Available Since

   Nov. 16, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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9. pVAX1-BMP2

   Plasmid

   #137909

   Purpose

   Constitutive mammalian overexpression vector for human bone morphogenetic protein 2 cDNA

   Depositor

   Georg Feichtinger

   Article

   Feichtinger et al Eur Cell Mater. 2014 Feb 19;27:166-84; d

   Insert

   BMP2 (BMP2 Human)
   

   Expression

   Mammalian

   Promoter

   CMV

   Available Since

   March 16, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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10. pSBbi G418 Hu CD19

    Plasmid

    #183247

    Purpose

    Expression of human CD19 antigen in a Sleeping Beauty transposon vector

    Depositor

    Alexander McLellan

    Article

    Dobson et al Immunol Cell Biol. 2023 Aug 16. doi: 10.

    Insert

    CD19 (CD19 Human)
    

    Expression

    Mammalian

    Available Since

    Oct. 13, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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11. NG-ABE8e

    Plasmid

    #138491

    Purpose

    A-to-G base editor

    Depositor

    David Liu

    Article

    Richter et al Nat Biotechnol. 2020 Jul;38(7):883-891.

    Insert

    ecTadA(8e)-nSpCas9 (NG)
    

    Expression

    Mammalian

    Available Since

    March 16, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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12. VN-Tau (wt)

    Plasmid

    #87368

    Purpose

    expresses hTau fused to the N-terminal part of Venus

    Depositor

    Tiago Outeiro

    Article

    Blum et al Hum Mol Genet. 2015 Jan 1;24(1):76-85. d

    Insert

    MAPT (MAPT Human)
    

    Tags

    N-terminal part of Venus

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    May 5, 2017

    Availability

    Academic Institutions and Nonprofits only

    

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13. pLJC6-3XHA-TMEM192

    Plasmid

    #104434

    Purpose

    Expresses 3XHA-TMEM192 in mammalian cells

    Depositor

    David Sabatini

    Article

    Wyant et al Cell. 2017 Oct 19;171(3):642-654.e12. do

    Insert

    TMEM192 (TMEM192 Human)
    

    Use

    Lentiviral

    Tags

    3XHA

    Expression

    Mammalian

    Promoter

    Ubiquitin

    Available Since

    July 2, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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14. pSH-Csy4-T2A-SpRFN-P2A-GFP-multi-gRNA

    Plasmid

    #85756

    Purpose

    All in one plasmid that expresses Csy4, S.pyogenes FokI-dCas9-NLS, and GFP. Also encodes for multiplexed gRNAs. Backbone derived from pSQT1601 (Addgene #53369).

    Depositor

    Lawrence Stanton

    Article

    Havlicek et al Mol Ther. 2017 Feb 1;25(2):342-355. doi:

    Inserts

    Csy4-T2A-SpRFN-P2A-GFP
    gRNA
    

    Use

    CRISPR

    Tags

    Csy4, Csy4 recognition sequence, FokI fusion via …

    Expression

    Mammalian

    Mutation

    D10A, H840A

    Promoter

    CMV and U6

    Available Since

    Jan. 20, 2017

    Availability

    Academic Institutions and Nonprofits only

    

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15. pCS2-Myc-TRIP12-CD

    Plasmid

    #241814

    Purpose

    Expresses Myc-tagged catalytic dead TRIP12 in mammalian cells.

    Depositor

    Ethan Lee

    Article

    Kassel et al Nat Commun. 2025 Jun 5;16(1):5248. doi:

    Insert

    TRIP12 (TRIP12 Human)
    

    Tags

    Myc

    Expression

    Mammalian

    Mutation

    catalytic dead (C2007A)

    Available Since

    Aug. 6, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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16. pSynSRE-Mut-T-Luc

    Plasmid

    #60490

    Purpose

    Contains a mutant version of the WT pSynSRE-T-Luc reporter plasmid. Four point mutations in the promoter SRE elements abolish SREBP-induced luciferase expression as described by Smith et al., 1988

    Depositor

    Timothy Osborne

    Article

    Smith et al J Biol Chem. 1988 Dec 5;263(34):18480-7.

    Insert

    HMG-CoA synthase promoter (-324/-225) fused to HMG-CoA synthase TATAA (-28/+39) transcription initiator sequence
    

    Use

    Luciferase

    Tags

    Luciferase reporter

    Expression

    Mammalian

    Mutation

    Four point mutations (G->C or A->C) in the …

    Promoter

    Partial HMG-CoA synthase promoter (-324/-225) fus…

    Available Since

    Feb. 9, 2016

    Availability

    Academic Institutions and Nonprofits only

    

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17. TFAM-SNAPf

    Plasmid

    #187909

    Purpose

    Mammalian cell expression of SNAPf-labeled TFAM

    Depositor

    Erika Holzbaur

    Article

    Harding et al Mol Cell. 2023 Sep 7;83(17):3188-3204.e7

    Insert

    TFAM (TFAM Human)
    

    Tags

    SNAPf

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    April 2, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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18. pAS088

    Plasmid

    #211502

    Purpose

    AAV genome backbone for AAV-Perturb-seq with direct gRNA capture and nuclei sorting based on eGFP.

    Depositor

    Randall Platt

    Article

    Santinha et al Nature. 2023 Oct;622(7982):367-375. doi:

    Type

    Empty backbone

    Use

    AAV, CRISPR, Cre/Lox, and Mouse Targeting

    Expression

    Mammalian

    Available Since

    Dec. 21, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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19. MSCV-CMV-DsRed-IRES-d1EGFP

    Plasmid

    #41942

    Purpose

    Retroviral expression of DsRed in mammalian cells

    Depositor

    Stephen Elledge

    Article

    Yen et al Science. 2008 Nov 7;322(5903):918-23. do

    Insert

    DsRed
    

    Use

    Retroviral

    Expression

    Mammalian

    Promoter

    TRE

    Available Since

    May 2, 2013

    Availability

    Academic Institutions and Nonprofits only

    

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20. mCherry-Moesin-N-14

    Plasmid

    #55104

    Purpose

    Localization: Cytoskeleton/Membrane, Excitation: 587, Emission: 610

    Depositor

    Michael Davidson

    Insert

    Moesin (MSN Human)
    

    Tags

    mCherry

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    Sept. 17, 2014

    Availability

    Academic Institutions and Nonprofits only