78,130 results

1. pcDNA3.1(+)-RasAR-NES

   Plasmid

   #205567

   Purpose

   Genetically encoded FRET-based biosensor for monitoring cellular Ras GTPase activity. Targeted to cytosol.

   Depositor

   Jin Zhang

   Article

   Weeks et al J Am Chem Soc. 2022 Sep 28;144(38):17432

   Insert

   RasAR-NES (RAF1 Synthetic, Human)
   

   Tags

   Nuclear export signal (NES)

   Expression

   Mammalian

   Promoter

   CMV

   Available Since

   Oct. 2, 2023

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

2. pCMV-T7-ABEmax-SpRY

   Plasmid

   #195279

   Purpose

   Allows for in vitro transcription of original pCMV-T7-ABEmax(7.10)-SpRY-P2A-EGFP (RTW5025) without EGFP

   Depositor

   Carsten Lederer, Petros Patsali

   Insert

   human codon optimized ABEmax(7.10) SpCas9 variant named SpRY without EGFP
   

   Expression

   Mammalian

   Promoter

   CMV

   Available Since

   June 1, 2023

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

3. pCAG-CBE4max-SpRYc-P2A-EGFP

   Plasmid

   #208336

   Purpose

   CAG promoter expression plasmid for human codon optimized BE4max C-to-T base editor with SpRYc

   Depositor

   Pranam Chatterjee

   Article

   Zhao et al Nat Commun. 2023 Oct 4;14(1):6175. doi:

   Insert

   human codon optimized CBE4max Cas9 variant named SpRYc with P2A-EGFP
   

   Use

   CRISPR

   Tags

   P2A-EGFP

   Expression

   Mammalian

   Mutation

   Sc++ (1-1119), SpRY (1111-1368), D10A

   Promoter

   CAG

   Available Since

   Oct. 11, 2023

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

4. pCW-eGFP

   Plasmid

   #162823

   Purpose

   Doxycycline-inducible overexpression of eGFP

   Depositor

   Matthew Steinhauser

   Article

   Fazeli et al Mol Metab. 2020 Sep 28;42:101082. doi: 1

   Insert

   eGFP
   

   Use

   Lentiviral

   Expression

   Mammalian

   Mutation

   V163A

   Promoter

   Tet ON

   Available Since

   Feb. 3, 2021

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

5. pPB-CAG-ARID1A-FLAG

   Plasmid

   #242209

   Purpose

   Expression of full-length human ARID1A using piggyBac transposition

   Depositor

   Courtney Hodges

   Article

   Chan et al Mol Cell. 2025 Jul 15:S1097-2765(25)0057

   Insert

   ARID1A (ARID1A Human)
   

   Use

   Piggybac

   Tags

   FLAG

   Expression

   Mammalian

   Promoter

   CAG

   Available Since

   Sept. 9, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

6. PP1Cg-HaloTag Fusion Vector

   Plasmid

   #236950

   Purpose

   Express PP1Cg-HaloTag(R) Fusion Protein in Mammalian Cells under a CMV promoter

   Depositor

   Promega Corporation

   Has Service

   DNA

   Insert

   PP1Cg (PPP1CC Human)
   

   Tags

   HaloTag (R)

   Expression

   Mammalian

   Mutation

   None

   Promoter

   CMV

   Available Since

   July 14, 2025

   Availability

   Industry, Academic Institutions, and Nonprofits

   

   Enlarge

7. HaloTag-PP1Cg Fusion Vector

   Plasmid

   #236951

   Purpose

   Express HaloTag(R)-PP1Cg Fusion Protein in Mammalian Cells under a CMV promoter

   Depositor

   Promega Corporation

   Has Service

   DNA

   Insert

   PP1Cg (PPP1CC Human)
   

   Tags

   HaloTag (R)

   Expression

   Mammalian

   Mutation

   None

   Promoter

   CMV

   Available Since

   July 14, 2025

   Availability

   Industry, Academic Institutions, and Nonprofits

   

   Enlarge

8. P022-mPB-TRE-PEmax-T2A-mCherry-PGK-rttA-Puro

   Plasmid

   #239974

   Purpose

   PiggyBac plasmid for inducible PEmax expression and Puromycin selection

   Depositor

   Jay Shendure

   Article

   Chen et al Nature. 2024 Aug;632(8027):1073-1081. do

   Type

   Empty backbone

   Use

   CRISPR and Synthetic Biology

   Expression

   Mammalian

   Promoter

   TRE

   Available Since

   June 26, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

9. pLV-Puro-{CMV-CuO}>{PAX3::FOXO1}:T2A:mCherry

   Plasmid

   #236629

   Purpose

   Puromycin selected lentiviral construct with cumate-inducible PAX3::FOXO1

   Depositor

   Genevieve Kendall

   Article

   Kent et al Sci Rep. 2024 Sep 5;14(1):20773. doi: 10

   Inserts

   PAX3::FOXO1 (FOXO1, PAX3 Human)
   mCherry
   

   Use

   Lentiviral

   Expression

   Mammalian

   Promoter

   CMV-CuO

   Available Since

   June 12, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

10. pDEST-mScarlet-SH3PXD2A

    Plasmid

    #215534

    Purpose

    Expression vector with Tks5 tagged with N-terminal mScarlet

    Depositor

    Johanna Ivaska

    Article

    Conway et al Nat Cell Biol. 2025 May 26. doi: 10.1038

    Insert

    SH3PXD2A (SH3PXD2A Human)
    

    Tags

    mScarlet

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    May 29, 2025

    Availability

    Industry, Academic Institutions, and Nonprofits

    

    Enlarge

11. TDP-43 ΔNTD GFP

    Plasmid

    #237546

    Purpose

    Expression of GFP-tag fused to mutant TDP-43 ΔNTD

    Depositor

    Tatyana Shelkovnikova

    Insert

    GFP-tagged TDP-43 ΔNTD (TARDBP Human)
    

    Tags

    EGFP

    Expression

    Mammalian

    Mutation

    TDP-43 1-90 a.a. deletion (TDP-43 35kDa)

    Promoter

    CMV

    Available Since

    May 13, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

12. pCAG-eCas9-T2A-EGFP-U6-gRNA-no ITR and f1 ori

    Plasmid

    #234724

    Purpose

    All-in-one CRISPR/Cas9 vector with high-fidelity eSpCas9 expression in neurons. The plasmid lacks AAV2 ITR and f1 ori elements, enabling more efficient transfection and expression.

    Depositor

    Kirill Martemyanov

    Article

    Zhao et al Nat Commun. 2025 Apr 22;16(1):3768. doi:

    Type

    Empty backbone

    Use

    CRISPR

    Tags

    T2A-GFP

    Expression

    Mammalian

    Promoter

    CAG promoter

    Available Since

    April 22, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

13. pRDA355_sgCiPELO #2

    Plasmid

    #229020

    Purpose

    Expression of a CRISPRi doxycycline inducible guide targeting PELO

    Depositor

    Francisca Vazquez

    Article

    Borck et al Nature. 2025 Feb 5. doi: 10.1038/s41586-

    Insert

    PELO gRNA
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Available Since

    April 3, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

14. pUB_mCherry-Rluc100

    Plasmid

    #210600

    Purpose

    Expresses mCherry-Optimal Renilla

    Depositor

    Olivia Rissland

    Article

    Barrington et al Cell Rep. 2023 Dec 26;42(12):113413. doi

    Insert

    mCherry-Optimal Renilla
    

    Use

    Lentiviral and Luciferase

    Tags

    mCherry

    Expression

    Mammalian

    Promoter

    UBC human

    Available Since

    Dec. 12, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

15. CL20_mEGFP_SPAG9_SKAP1

    Plasmid

    #205925

    Purpose

    Express mEGFP-tagged fusion protein, SPAG9_SKAP1 from patient-derived sequence

    Depositor

    Richard Kriwacki

    Article

    Tripathi et al Nat Commun. 2023 Sep 28;14(1):6008. doi:

    Insert

    SPAG9_SKAP1 (SPAG9, SKAP1 Human)
    

    Tags

    mEGFP

    Expression

    Mammalian

    Available Since

    Nov. 9, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

16. EK0441 CMV-TO-BFPmut-stop-EGFP.t2 (FLP-IN)

    Plasmid

    #191161

    Purpose

    Expression of a trigger sequence from EGFP CDS in 3' UTR context in mammalian cells

    Depositor

    Xiaojing Gao

    Article

    Kaseniit et al Nat Biotechnol. 2022 Oct 5. pii: 10.1038

    Insert

    EGFP.t2
    

    Expression

    Mammalian

    Mutation

    WT

    Promoter

    CMV-TO

    Available Since

    Oct. 26, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. pBI-CMV1-mir144[3072 nt]~451-CMV2-mir1

    Plasmid

    #164682

    Purpose

    Express miR-144[3072 nt]~451 and miR-1-1 in mammalian cells

    Depositor

    David Bartel

    Article

    Fang et al Mol Cell. 2020 Apr 16;78(2):289-302.e6.

    Inserts

    miR-144[3072 nt]~451 (MIR144 Human)
    mir-1-1 (MIR1-1 Human)
    

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    March 14, 2021

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. SSTR5-Tango

    Plasmid

    #66506

    Purpose

    Expression of G protein-coupled receptors for PRESTO-Tango: parallel receptorome expression and screening via transcriptional output, with transcriptional activation following arrestin translocation

    Depositor

    Bryan Roth

    Article

    Kroeze et al Nat Struct Mol Biol. 2015 May;22(5):362-

    Insert

    SSTR5 (SSTR5 Human)
    

    Tags

    FLAG

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    Sept. 15, 2015

    Availability

    Academic Institutions and Nonprofits only

19. pCAG-Autobow

    Plasmid

    #45182

    Depositor

    Joshua Sanes

    Article

    Cai et al Nat Methods. 2013 May 5;10(6):540-7. doi

    Insert

    pCAG-Autobow
    

    Expression

    Mammalian

    Promoter

    CAG

    Available Since

    Nov. 19, 2013

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. pLenti-DENV2A-GFP-puro

    Plasmid

    #140089

    Purpose

    Fluorescence activatable reporter of DENV-2 NS2B-NS3 protease activity

    Depositor

    Jorge Luis Arias-Arias

    Article

    Arias-Arias et al J Biol Chem. 2020 Jan 9. pii: RA119.0113

    Insert

    DENV2A-GFP
    

    Use

    Lentiviral; Low expression

    Tags

    6XHis tag and GFP

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    Sept. 23, 2020

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge