We narrowed to 12,639 results for: icos

1. sgLATS1/2-2

   Plasmid

   #229432

   Purpose

   knockout of LATS1 and LATS2

   Depositor

   Christopher Vakoc

   Article

   Klingbeil et al Cancer Discov. 2024 Jul 26. doi: 10.1158

   Insert

   sgLATS1/2-2 (LATS1, LATS2 Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   hU6;bU6;EFS

   Available since

   Dec. 18, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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2. sgLATS1/2-1

   Plasmid

   #229431

   Purpose

   knockout of LATS1 and LATS2

   Depositor

   Christopher Vakoc

   Article

   Klingbeil et al Cancer Discov. 2024 Jul 26. doi: 10.1158

   Insert

   sgLATS1/2-1 (LATS1, LATS2 Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   hU6;bU6;EFS

   Available since

   Dec. 18, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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3. sgMST1/2-2

   Plasmid

   #229430

   Purpose

   knockout of MST1 and MST2

   Depositor

   Christopher Vakoc

   Article

   Klingbeil et al Cancer Discov. 2024 Jul 26. doi: 10.1158

   Insert

   sgMST1/2-2 (MST1, STK3 Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   hU6;bU6;EFS

   Available since

   Dec. 18, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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4. sgMST1/2-1

   Plasmid

   #229429

   Purpose

   knockout of MST1 and MST2

   Depositor

   Christopher Vakoc

   Article

   Klingbeil et al Cancer Discov. 2024 Jul 26. doi: 10.1158

   Insert

   sgMST1/2-1 (MST1, STK3 Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   hU6;bU6;EFS

   Available since

   Dec. 18, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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5. pInducer-myc-ERK1-S170D

   Plasmid

   #213592

   Purpose

   Doxycycline inducible expression of myc-tagged ERK1-S170D cDNA in mammilian cells

   Depositor

   Channing Der

   Article

   Klomp et al Science. 2024 Jun 7;384(6700):eadk0850.

   Insert

   MAPK3 (MAPK3 Human)
   

   Use

   Lentiviral

   Tags

   MYC

   Expression

   Mammalian

   Mutation

   S170D

   Promoter

   Available since

   Aug. 23, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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6. pInducer-myc-ERK1-R84S/D338N

   Plasmid

   #213594

   Purpose

   Doxycycline inducible expression of myc-tagged ERK1-R84S/D338N cDNA in mammilian cells

   Depositor

   Channing Der

   Article

   Klomp et al Science. 2024 Jun 7;384(6700):eadk0850.

   Insert

   MAPK3 (MAPK3 Human)
   

   Use

   Lentiviral

   Tags

   MYC

   Expression

   Mammalian

   Mutation

   R84S, D338N

   Promoter

   Available since

   Aug. 23, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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7. pcDNA3.1+FLAG-KrascomQ61R

   Plasmid

   #206845

   Purpose

   To express mouse Kras encoded by common mouse codons (to increase expression) and with a Q61R mutation with an N-terminal FLAG tag.

   Depositor

   Christopher Counter

   Article

   Le Roux et al Elife. 2022 Sep 7;11:e75715. doi: 10.755

   Insert

   Kras (Kras Mouse)
   

   Use

   Tags

   FLAG

   Expression

   Mammalian

   Mutation

   Codons altered to most optimum based on mouse cod…

   Promoter

   Available since

   July 31, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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8. pSCBE3-NG-HF1-Hypa

   Plasmid

   #218162

   Purpose

   This plasmid harbors the base editor SCBE3-NG-HF1-Hypa along with an sgRNA cloning cassette, facilitating high-fidelity cytosine base editing at targets bearing NG PAM in Streptomyces.

   Depositor

   Yuhui Sun

   Article

   Wang et al Nat Commun. 2024 Jul 7;15(1):5687. doi:

   Inserts

   scbe3-NG-HF1-Hypa
   a programmable sgRNA cloning cassette
   

   Use

   CRISPR; Sgrna transcription

   Tags

   Expression

   Bacterial

   Mutation

   Mutations in the portion of SpCas9 : D10A / N497A…

   Promoter

   rpsL promoter

   Available since

   May 13, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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9. pCMV_msfGFP-SEPT7 Gmut2

   Plasmid

   #180425

   Purpose

   mammalian expression of human SEPT7 Gmut2 fused to monomeric superfolder GFP

   Depositor

   Manos Mavrakis

   Article

   Martins et al J Cell Biol. 2023 Mar 6;222(3):e20220301

   Insert

   SEPTIN7 (SEPTIN7 Human)
   

   Use

   Tags

   msfGFP

   Expression

   Mammalian

   Mutation

   SEPT7 H279D

   Promoter

   CMV

   Available since

   Dec. 1, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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10. pCMV_SEPT9_i3 Gmut-msfGFP

    Plasmid

    #180326

    Purpose

    mammalian expression of human SEPT9_i3 Gmut fused to monomeric superfolder GFP

    Depositor

    Manos Mavrakis

    Article

    Martins et al J Cell Biol. 2023 Mar 6;222(3):e20220301

    Insert

    SEPTIN9_v3 (SEPTIN9 Human)
    

    Use

    Tags

    msfGFP

    Expression

    Mammalian

    Mutation

    SEPT9_i3 W502A, H512D

    Promoter

    CMV

    Available since

    Dec. 1, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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11. pnEA-vH_His-TEV-SEPT2 NCmut-msfGFP

    Plasmid

    #180311

    Purpose

    bacterial expression of human SEPT2 NCmut fused to monomeric superfolder GFP

    Depositor

    Manos Mavrakis

    Article

    Martins et al J Cell Biol. 2023 Mar 6;222(3):e20220301

    Insert

    SEPTIN2 (SEPTIN2 Human)
    

    Use

    Tags

    His6-TEV and msfGFP

    Expression

    Bacterial

    Mutation

    SEPT2 F20D, V27D

    Promoter

    Available since

    Dec. 1, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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12. pCMV_msfGFP-SEPT7 Gmut1

    Plasmid

    #180316

    Purpose

    mammalian expression of human SEPT7 Gmut1 fused to monomeric superfolder GFP

    Depositor

    Manos Mavrakis

    Article

    Martins et al J Cell Biol. 2023 Mar 6;222(3):e20220301

    Insert

    SEPTIN7 (SEPTIN7 Human)
    

    Use

    Tags

    msfGFP

    Expression

    Mammalian

    Mutation

    SEPT7 W269A, H279D

    Promoter

    CMV

    Available since

    Dec. 1, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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13. pCMV_SEPT9_i3-mApple-CAAX

    Plasmid

    #180324

    Purpose

    mammalian expression of human SEPT9_i3 fused to monomeric Apple and CAAX (HRas)

    Depositor

    Manos Mavrakis

    Article

    Martins et al J Cell Biol. 2023 Mar 6;222(3):e20220301

    Insert

    SEPTIN9_v3 (SEPTIN9 Human)
    

    Use

    Tags

    mApple

    Expression

    Mammalian

    Mutation

    Promoter

    CMV

    Available since

    Dec. 1, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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14. pCMV_SEPT9_i3 NCmut-msfGFP

    Plasmid

    #180325

    Purpose

    mammalian expression of human SEPT9_i3 NCmut fused to monomeric superfolder GFP

    Depositor

    Manos Mavrakis

    Article

    Martins et al J Cell Biol. 2023 Mar 6;222(3):e20220301

    Insert

    SEPTIN9_v3 (SEPTIN9 Human)
    

    Use

    Tags

    msfGFP

    Expression

    Mammalian

    Mutation

    SEPT9_i3 I263D, M270D

    Promoter

    CMV

    Available since

    Dec. 1, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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15. pAB(EXPR-DS-HDAC5_HDAC3)

    Plasmid

    #114399

    Purpose

    For PYL-HDAC5 catalytic domain swap to HDAC3 catalytic domain expression

    Depositor

    Vincent Dion

    Article

    Yang et al Hum Mol Genet. 2021 Sep 7. pii: 6365982.

    Insert

    PYL-HDAC5_HDAC3 catalytic domain swap (HDAC3, HDAC5 Human)
    

    Use

    Tags

    3xFlag-NLS (internal)

    Expression

    Mammalian

    Mutation

    Promoter

    CMV

    Available since

    Oct. 13, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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16. pNB1-LOX

    Plasmid

    #154058

    Purpose

    Level 1, Position 3 Golden Gate vector. ZmUbi-5'UTR:loxP-GUS-nosT-loxP-NAM-B1-nosT

    Depositor

    Cristobal Uauy

    Article

    Harrington et al Plant Methods. 2020 Oct 14;16:137. doi:

    Insert

    LoxP-flanked GUS and TtNAM-B1
    

    Use

    Synthetic Biology

    Tags

    Expression

    Bacterial

    Mutation

    The TtNAM-B1 gene sequence was domesticated to re…

    Promoter

    ZmUbi

    Available since

    Sept. 29, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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17. RALA V25L

    Plasmid

    #122927

    Purpose

    Bacterial expression of RALA V25L

    Depositor

    Greg Cooper

    Article

    Hiatt et al PLoS Genet. 2018 Nov 30;14(11):e1007671.

    Insert

    RALA (RALA Human)
    

    Use

    Tags

    His

    Expression

    Bacterial

    Mutation

    V25L

    Promoter

    T7

    Available since

    April 4, 2019

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. RALA V25M

    Plasmid

    #122928

    Purpose

    Bacterial expression of RALA V25M

    Depositor

    Greg Cooper

    Article

    Hiatt et al PLoS Genet. 2018 Nov 30;14(11):e1007671.

    Insert

    RALA (RALA Human)
    

    Use

    Tags

    His

    Expression

    Bacterial

    Mutation

    V25M

    Promoter

    T7

    Available since

    April 4, 2019

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. RALA D130G

    Plasmid

    #122929

    Purpose

    Bacterial expression of RALA D130G

    Depositor

    Greg Cooper

    Article

    Hiatt et al PLoS Genet. 2018 Nov 30;14(11):e1007671.

    Insert

    RALA (RALA Human)
    

    Use

    Tags

    His

    Expression

    Bacterial

    Mutation

    D130G

    Promoter

    T7

    Available since

    April 4, 2019

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. RALA S157A

    Plasmid

    #122930

    Purpose

    Bacterial expression of RALA S157A

    Depositor

    Greg Cooper

    Article

    Hiatt et al PLoS Genet. 2018 Nov 30;14(11):e1007671.

    Insert

    RALA (RALA Human)
    

    Use

    Tags

    His

    Expression

    Bacterial

    Mutation

    S157A

    Promoter

    T7

    Available since

    April 4, 2019

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge