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pINDUCER20-PTPN12(D199A,C231S)

Plasmid

#215518

Purpose

Dox-inducible lentiviral transfer vector with a phosphatase-inactive PTP-PEST mutant (D199A,C231S)

Depositor

Johanna Ivaska

Article

Conway et al Nat Cell Biol. 2025 May 26. doi: 10.1038

Insert

PTPN12 (PTPN12 Human)

Use

Lentiviral

Mutation

D199A, C231S (Phosphatase inactive)

Promoter

mCMV, Doxycycline-inducible

Available Since

May 29, 2025

Availability

Industry, Academic Institutions, and Nonprofits

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pENTR2b-PTPN12(D199A,C231S)-Clover

Plasmid

#215522

Purpose

Gateway entry vector with a clover-tagged phosphatase-inactive PTP-PEST mutant (D199A,C231S)

Depositor

Johanna Ivaska

Article

Conway et al Nat Cell Biol. 2025 May 26. doi: 10.1038

Insert

PTPN12 (PTPN12 Human)

Use

Gateway entry vector

Tags

Clover

Mutation

D199A, C231S (Phosphatase inactive)

Promoter

none

Available Since

May 29, 2025

Availability

Industry, Academic Institutions, and Nonprofits

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pEF.DEST51-PTPN11

Plasmid

#215523

Purpose

Expression vector with Shp2

Depositor

Johanna Ivaska

Article

Conway et al Nat Cell Biol. 2025 May 26. doi: 10.1038

Insert

PTPN11 (PTPN11 Human)

Expression

Mammalian

Promoter

EF1a

Available Since

May 29, 2025

Availability

Industry, Academic Institutions, and Nonprofits

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pENTR221-ANXA6-mScarlet

Plasmid

#215473

Purpose

Gateway entry vector with Annexin A6 tagged with mScarlet

Depositor

Johanna Ivaska

Article

Conway et al Nat Cell Biol. 2025 May 26. doi: 10.1038

Insert

ANXA6 (ANXA6 Human)

Use

Gateway entry vector

Tags

mScarlet

Promoter

none

Available Since

May 29, 2025

Availability

Industry, Academic Institutions, and Nonprofits

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pBX_RPL29_smGFP_V5

Plasmid

#236091

Purpose

Constitutively encodes RPL29-smGFP-V5 (sfGFP-based spaghetti monster fluorescent protein embedding V5 epitope tags), for targeting RPL29 in the 60S subunit.

Depositor

Maria Barna

Article

Zhang et al Science. 2025 Mar 7;387(6738):eadn2623.

Insert

RPL29-smGFP-V5 (RPL29 Human, Synthetic)

Expression

Mammalian

Available Since

April 8, 2025

Availability

Academic Institutions and Nonprofits only

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pCAGEN_NES_V5_eMagAF_C74_MAVS

Plasmid

#235638

Purpose

Encodes ALIBi C-terminal fragment, residues 74-321, fused to eMagAF (enhanced Magnet, acidic, fast), V5, nuclear export sequence, MAVS residues 500-540 for targeting to outer mitochondrial membrane

Depositor

Maria Barna

Article

Zhang et al Science. 2025 Mar 7;387(6738):eadn2623.

Insert

ALIBi C-terminal fragment

Tags

MAVS and NES-V5-eMagAF

Expression

Mammalian

Mutation

residues 74-321

Available Since

April 2, 2025

Availability

Academic Institutions and Nonprofits only

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pEIF3D-RNAgateDel-sgEIF3D

Plasmid

#222137

Purpose

EIF3D variant overexpression vector with sgRNA targeting eIF3D

Depositor

Jonathan Weissman

Article

She et al Nucleic Acids Res. 2023 Jul 7;51(12):635

Insert

eIF3D (EIF3D Human)

Use

Lentiviral

Tags

BFP-P2A

Mutation

V291-F306 deletion

Available Since

Feb. 3, 2025

Availability

Academic Institutions and Nonprofits only

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pUC-hU6-crBACH1-array_EF1a-BFP

Plasmid

#224787

Purpose

BACH1 targeting crRNA array for RfxCas13d expressed from multiple hU6 promoter and reporter BFP protein expressed from EF1a promoter

Depositor

Gabor Balazsi

Article

Wan et al ACS Synth Biol. 2024 Oct 18;13(10):3212-

Insert

crBACH1-1, crBACH1-2, crBACH1-3,

Use

CRISPR and Synthetic Biology

Expression

Mammalian

Promoter

hU6 and hU6-2xTetO

Available Since

Oct. 31, 2024

Availability

Academic Institutions and Nonprofits only

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pUt-mNF-Cas13d

Plasmid

#224789

Purpose

LPUtopia matching RMCE donor plasmid with mCherry-P2A-RfxCas13d Negative-Feedback circuit. Use BlastR for positive selection and HSV-TK for negative selection.

Depositor

Gabor Balazsi

Article

Wan et al ACS Synth Biol. 2024 Oct 18;13(10):3212-

Insert

mCherry-P2A-RfxCas13d

Use

CRISPR and Synthetic Biology

Expression

Mammalian

Promoter

CMV-d2i

Available Since

Oct. 31, 2024

Availability

Academic Institutions and Nonprofits only

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LPUtopia-7_CoV-2

Plasmid

#224782

Purpose

Landing Pad donor vector containing partial RdRp and N gene sequences from SARS-CoV-2 for fluorescent reporter assay

Depositor

Gabor Balazsi

Article

Wan et al ACS Synth Biol. 2024 Oct 18;13(10):3212-

Insert

partial RdRp and N gene (N, ORF1ab SARS-CoV-2)

Expression

Mammalian

Available Since

Oct. 31, 2024

Availability

Academic Institutions and Nonprofits only

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pEIF3D-a11helixDel-sgEIF3D

Plasmid

#222135

Purpose

EIF3D variant overexpression vector with sgRNA targeting eIF3D

Depositor

Jonathan Weissman

Article

She et al Nucleic Acids Res. 2023 Jul 7;51(12):635

Insert

eIF3D (EIF3D Human)

Use

Lentiviral

Tags

BFP-P2A

Mutation

T317E, N320E, H321A

Available Since

Oct. 11, 2024

Availability

Academic Institutions and Nonprofits only

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pEIF3D-CtermDel-sgEIF3D

Plasmid

#222125

Purpose

EIF3D variant overexpression vector with sgRNA targeting eIF3D

Depositor

Jonathan Weissman

Article

She et al Nucleic Acids Res. 2023 Jul 7;51(12):635

Insert

eIF3D (EIF3D Human)

Use

Lentiviral

Tags

BFP-P2A

Mutation

F527 truncation

Available Since

Oct. 11, 2024

Availability

Academic Institutions and Nonprofits only

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pEIF3D-a5helixDel-sgEIF3D

Plasmid

#222133

Purpose

EIF3D variant overexpression vector with sgRNA targeting eIF3D

Depositor

Jonathan Weissman

Article

She et al Nucleic Acids Res. 2023 Jul 7;51(12):635

Insert

eIF3D (EIF3D Human)

Use

Lentiviral

Tags

BFP-P2A

Mutation

D249Q, V262I, Y263A

Available Since

Oct. 11, 2024

Availability

Academic Institutions and Nonprofits only

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pAcGFP-N1_CBPdIDR7-H1

Plasmid

#221930

Purpose

Transient expression of GFP-tagged CBPdeltaIDR7-H1 in mammalian cells

Depositor

Daniel Bose

Article

Gelder et al Cell Rep. 2026 Mar 12;45(3):117109. doi:

Insert

CBPdeltaIDR7-H1 (CREBBP Human)

Tags

GFP

Expression

Mammalian

Mutation

deletion of IDR7, CBP aa 2187 - 2216

Available Since

June 28, 2024

Availability

Academic Institutions and Nonprofits only

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pAcGFP-N1_CBPdIDR6

Plasmid

#221907

Purpose

Transient expression of GFP-tagged CBPdeltaIDR6 in mammalian cells

Depositor

Daniel Bose

Article

Gelder et al Cell Rep. 2026 Mar 12;45(3):117109. doi:

Insert

CBPdeltaIDR6 (CREBBP Human)

Tags

GFP

Expression

Mammalian

Mutation

deletion of IDR6 (aa 1856-2090)

Available Since

June 28, 2024

Availability

Academic Institutions and Nonprofits only

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pAcGFP-N1_CBPdIDR4

Plasmid

#221906

Purpose

Transient expression of GFP-tagged CBPdeltaIDR4 in mammalian cells

Depositor

Daniel Bose

Article

Gelder et al Cell Rep. 2026 Mar 12;45(3):117109. doi:

Insert

CBPdeltaIDR4 (CREBBP Human)

Tags

GFP

Expression

Mammalian

Mutation

deletion of IDR4 (aa 662-787)

Available Since

June 28, 2024

Availability

Academic Institutions and Nonprofits only

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pAcGFP-N1_CBPdIDR6-H2

Plasmid

#221929

Purpose

Transient expression of GFP-tagged CBPdeltaIDR6-H2 in mammalian cells

Depositor

Daniel Bose

Article

Gelder et al Cell Rep. 2026 Mar 12;45(3):117109. doi:

Insert

CBPdeltaIDR6-H2 (CREBBP Human)

Tags

GFP

Expression

Mammalian

Mutation

deletion of IDR6, CBP aa 1951 - 1978

Available Since

June 28, 2024

Availability

Academic Institutions and Nonprofits only

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pAcGFP-N1_CBPdIDR1

Plasmid

#221904

Purpose

Transient expression of GFP-tagged CBPdeltaIDR1 in mammalian cells

Depositor

Daniel Bose

Article

Gelder et al Cell Rep. 2026 Mar 12;45(3):117109. doi:

Insert

CBPdeltaIDR1 (CREBBP Human)

Tags

GFP

Expression

Mammalian

Mutation

deletion of IDR1 (aa 72-175)

Available Since

June 28, 2024

Availability

Academic Institutions and Nonprofits only

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pAcGFP-N1_CBPdIDR7

Plasmid

#221908

Purpose

Transient expression of GFP-tagged CBPdeltaIDR7 in mammalian cells

Depositor

Daniel Bose

Article

Gelder et al Cell Rep. 2026 Mar 12;45(3):117109. doi:

Insert

CBPdeltaIDR7 (CREBBP Human)

Tags

GFP

Expression

Mammalian

Mutation

deletion of IDR7 (aa 2109-2434)

Available Since

June 28, 2024

Availability

Academic Institutions and Nonprofits only

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pAcGFP-N1_CBPdIDR3

Plasmid

#221905

Purpose

Transient expression of GFP-tagged CBPdeltaIDR3 in mammalian cells

Depositor

Daniel Bose

Article

Gelder et al Cell Rep. 2026 Mar 12;45(3):117109. doi:

Insert

CBPdeltaIDR3 (CREBBP Human)

Tags

GFP

Expression

Mammalian

Mutation

deletion of IDR3 (aa 441-587)

Available Since

June 28, 2024

Availability

Academic Institutions and Nonprofits only

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