We narrowed to 1,752 results for: krab

1. pLX303-ABI1-dCas9

   Plasmid

   #154474

   Purpose

   Expresses ABI1 fused to the N terminus of dCas9

   Depositor

   Mikko Taipale

   Article

   Alerasool et al Nat Methods. 2020 Nov;17(11):1093-1096.

   Insert

   ABI1 (ABI1 Mustard Weed)
   

   Use

   Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Includes ABI1 aa 126-423, D143A

   Promoter

   CMV

   Available since

   Oct. 5, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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2. pGK:TRL-EFS:iRFP670

   Plasmid

   #68475

   Purpose

   Lentiviral plasmid expressing tTR-KRAB-rtTA3-Luc cassette and iRFP670

   Depositor

   Tyler Jacks

   Article

   Akama-Garren et al Sci Rep. 2016 Feb 18;6:16836. doi: 10.10

   Inserts

   tTR-KRAB-2A-rtTA3-2A-Luciferase
   iRFP670
   

   Use

   Lentiviral and Luciferase

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   EFS and pGK

   Available since

   Feb. 22, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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3. pROF018

   Plasmid

   #155325

   Purpose

   Constitutive expression of KRAB-EL222 in plants

   Depositor

   Matias Zurbriggen

   Article

   Ochoa-Fernandez et al Nat Methods. 2020 Jul;17(7):717-725. doi

   Insert

   PCaMV35S-NLS-KRAB-EL222-Tnos
   

   Use

   Synthetic Biology

   Tags

   Expression

   Plant

   Mutation

   Promoter

   Available since

   Oct. 26, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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4. pCMV6-ZNF354C_mutant_D17A-V18A

   Plasmid

   #194184

   Purpose

   Expresses ZNF354C with mutated KRAB domain (D17A, V18A mutation)

   Depositor

   Matthias Leisegang, Ralf Brandes

   Article

   Oo et al Sci Rep. 2020 Nov 5;10(1):19079. doi: 10

   Insert

   ZNF354C (ZNF354C Human)
   

   Use

   Tags

   Myc-DDK

   Expression

   Mammalian

   Mutation

   KRAB domain mutant D17A/V18A

   Promoter

   CMV

   Available since

   Jan. 24, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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5. pCMV6-ZNF354C_mutant_E25A-W26A

   Plasmid

   #194186

   Purpose

   Expresses ZNF354C with mutated KRAB domain (E25A, W26A mutation)

   Depositor

   Matthias Leisegang, Ralf Brandes

   Article

   Oo et al Sci Rep. 2020 Nov 5;10(1):19079. doi: 10

   Insert

   ZNF354C (ZNF354C Human)
   

   Use

   Tags

   Myc-DDK

   Expression

   Mammalian

   Mutation

   KRAB domain mutant E25A/W26A

   Promoter

   CMV

   Available since

   Jan. 24, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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6. pRT029

   Plasmid

   #127969

   Purpose

   double-DHFR-degron controlled expression of dCas9-BFP-KRAB from the CLYBL locus

   Depositor

   Martin Kampmann

   Article

   Tian et al Neuron. 2019 Aug 5. pii: S0896-6273(19)3

   Insert

   CLYBL-CAG-DHFR-dCas9-BFP-KRAB-DHFR
   

   Use

   TALEN

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   CAG

   Available since

   Aug. 24, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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7. LLP786_SpyCatcher-EZH2-FL-CO

   Plasmid

   #211779

   Purpose

   SpyTag counterpart binding domain, SpyCatcher, fused to polycomb repressive complex subunit EZH2, with GFP selection

   Depositor

   Ryan Lister

   Article

   Swain et al Nucleic Acids Res. 2023 Nov 24:gkad1108.

   Insert

   aGCN4-KRAB
   

   Use

   Tags

   3xTy1

   Expression

   Mammalian

   Mutation

   Last 300 bp codon-optimised (CO) to detect KRAB e…

   Promoter

   pEF1a and pSV40

   Available since

   Dec. 15, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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8. pIND(V5)EcoDam

   Plasmid

   #59201

   Purpose

   Mammalian DamID vector used to fuse gene of interest to V5-tagged E.coli Dam. Can also express Dam alone as negative control.

   Depositor

   Bas van Steensel

   Article

   Vogel et al Genome Res. 2006 Dec;16(12):1493-504. Ep

   Type

   Empty backbone

   Use

   Damid

   Tags

   Dam (DNA adenine methyltransferase) and V5

   Expression

   Mammalian

   Mutation

   Promoter

   Heat Shock Minimal Promoter

   Available since

   June 14, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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9. pLgw EcoDam-V5-RFC1

   Plasmid

   #59209

   Purpose

   Mammalian DamID lentiviral vector for fusing gene of interest with Dam-V5 using Gateway cloning

   Depositor

   Bas van Steensel

   Article

   Vogel et al Genome Res. 2006 Dec;16(12):1493-504. Ep

   Type

   Empty backbone

   Use

   Lentiviral; Damid

   Tags

   Dam and V5

   Expression

   Mammalian

   Mutation

   Promoter

   Heat Shock Minimal Promoter

   Available since

   June 14, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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10. pINDgw RFA-V5-EcoDam

    Plasmid

    #59204

    Purpose

    Mammalian DamID vector for fusing gene of interest with Dam-V5 using Gateway cloning

    Depositor

    Bas van Steensel

    Article

    Vogel et al Genome Res. 2006 Dec;16(12):1493-504. Ep

    Type

    Empty backbone

    Use

    Damid

    Tags

    Dam (DNA adenine methyltransferase) and V5

    Expression

    Mammalian

    Mutation

    Promoter

    Heat Shock Minimal Promoter

    Available since

    June 14, 2016

    Availability

    Academic Institutions and Nonprofits only

    

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11. R26TV LSL-TRL

    Plasmid

    #68476

    Purpose

    Rosa26 targeting vector expressing Cre-dependent tTR-KRAB-rtTA3-Luc cassette

    Depositor

    Tyler Jacks

    Article

    Akama-Garren et al Sci Rep. 2016 Feb 18;6:16836. doi: 10.10

    Insert

    tTR-KRAB-2A-rtTA3-2A-Luciferase
    

    Use

    Cre/Lox, Luciferase, and Mouse Targeting

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    CAG

    Available since

    Feb. 22, 2016

    Availability

    Academic Institutions and Nonprofits only

    

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12. LLP790_αGCN4-EZH2-FL-CO

    Plasmid

    #211784

    Purpose

    SunTag counterpart binding domain, aGCN4, fused to polycomb repressive complex subunit EZH2, with GFP selection

    Depositor

    Ryan Lister

    Article

    Swain et al Nucleic Acids Res. 2023 Nov 24:gkad1108.

    Insert

    SnoopCatcher-KRAB
    

    Use

    Tags

    2xOLLAS

    Expression

    Mammalian

    Mutation

    Last 300 bp codon-optimised (CO) to detect KRAB e…

    Promoter

    pEF1a and pSV40

    Available since

    Dec. 15, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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13. pCMV6-ZNF354C_mutant_M41K-L42K-E43K

    Plasmid

    #194185

    Purpose

    Expresses ZNF354C with mutated KRAB domain (M41K, L42K, E43K mutation)

    Depositor

    Matthias Leisegang, Ralf Brandes

    Article

    Oo et al Sci Rep. 2020 Nov 5;10(1):19079. doi: 10

    Insert

    ZNF354C (ZNF354C Human)
    

    Use

    Tags

    Myc-DDK

    Expression

    Mammalian

    Mutation

    KRAB domain mutant M41K/L42K/E43K

    Promoter

    CMV

    Available since

    Jan. 24, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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14. CRISPRoff-mScarletI

    Plasmid

    #217783

    Purpose

    Expresses CRISPRoff-mScarletI (DNMT3A-DNMT3L-XTEN80-dCas9-HA-2xNLS-mScarletI-KRAB) downstream of the CAG promoter for gene epigenetic silencing

    Depositor

    Adriano Aguzzi

    Article

    Yin et al Nat Biomed Eng. 2024 Dec 4. doi: 10.1038

    Insert

    CRISPRoff-mScarletI (DNMT3A-DNMT3L-dCas9-mScarletI-KRAB)
    

    Use

    Tags

    2xNLS, DNMT3A-DNMT3L, HA, KRAB, and mScarletI

    Expression

    Mammalian

    Mutation

    Promoter

    CAG

    Available since

    April 14, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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15. lentiCRISPRi(v2)-Blast

    Plasmid

    #170068

    Purpose

    Expresses dCas9 repressor KRAB-dCas9-MeCP2 and blasticidin resistance

    Depositor

    Neville Sanjana

    Article

    Morris et al Science. 2023 May 19;380(6646):eadh7699.

    Insert

    KRAB-dCas9-MeCP2
    

    Use

    CRISPR and Lentiviral

    Tags

    2A and 2xHA tag

    Expression

    Mammalian

    Mutation

    Promoter

    EFS-NS

    Available since

    Oct. 12, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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16. pLgw V5-EcoDam

    Plasmid

    #59210

    Purpose

    Mammalian DamID control lentiviral vector for expression of V5-Dam only

    Depositor

    Bas van Steensel

    Article

    Vogel et al Genome Res. 2006 Dec;16(12):1493-504. Ep

    Insert

    EcoDam
    

    Use

    Lentiviral; Damid

    Tags

    V5

    Expression

    Mammalian

    Mutation

    Promoter

    Heat Shock Minimal Promoter and heat shock minima…

    Available since

    June 14, 2016

    Availability

    Academic Institutions and Nonprofits only

    

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17. pSLQ10875

    Plasmid

    #183963

    Purpose

    CBA-hyperdCas12a-HA-KRAB-mCherry

    Depositor

    Stanley Qi

    Article

    Guo et al Nat Cell Biol. 2022 Apr;24(4):590-600. d

    Insert

    HyperdCas12a
    

    Use

    CRISPR

    Tags

    HA, KRAB, and mCherry

    Expression

    Mammalian

    Mutation

    D832A, D156R, E292R, D235R, D350R

    Promoter

    CBA

    Available since

    June 1, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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18. DNMT3L-dCas9

    Plasmid

    #126587

    Purpose

    DNMT3L fused to N-terminus of dCas9; pCDNA3 vector backbone, mammalian expression

    Depositor

    David Segal

    Article

    O'Geen et al Epigenetics Chromatin. 2019 May 3;12(1):

    Insert

    DNMT3L (DNMT3L Human)
    

    Use

    CRISPR

    Tags

    3XFLag-NLS-DNMT3L-dCas9-NLS

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    Dec. 12, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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19. lentiCRISPRi(v1)-Blast

    Plasmid

    #170067

    Purpose

    Expresses dCas9 repressor KRAB-dCas9 and blasticidin resistance

    Depositor

    Neville Sanjana

    Article

    Morris et al Science. 2023 May 19;380(6646):eadh7699.

    Insert

    KRAB-dCas9
    

    Use

    CRISPR and Lentiviral

    Tags

    2A and 2xHA tag

    Expression

    Mammalian

    Mutation

    Promoter

    EFS-NS

    Available since

    Oct. 12, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. pLgw RFC1-V5-EcoDam

    Plasmid

    #59205

    Purpose

    Mammalian DamID lentiviral vector for fusing gene of interest with Dam-V5 using Gateway cloning

    Depositor

    Bas van Steensel

    Article

    Vogel et al Genome Res. 2006 Dec;16(12):1493-504. Ep

    Type

    Empty backbone

    Use

    Lentiviral; Damid

    Tags

    Dam (DNA adenine methyltransferase) and V5

    Expression

    Mammalian

    Mutation

    Promoter

    Heat Shock Minimal Promoter

    Available since

    June 17, 2016

    Availability

    Academic Institutions and Nonprofits only

    

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