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Plasmid#123079PurposeGateway entry clone encoding human MAP1LC3C G126DepositorInsertMicrotubule-associated proteins 1A/1B light chain 3C (MAP1LC3C Human)
UseGateway entry vector / entry cloneTagsExpressionMutationDeleted amino acids 127-147. Stop codon after G12…PromoterAvailable sinceMay 14, 2019AvailabilityAcademic Institutions and Nonprofits only -
pET30a-SRAP-delCys2
Plasmid#84568PurposeEncodes murine SRAP domain (250aa) of Hmces/Srap1 with deletion of catalytic Cys2DepositorInsertSrap1 (Hmces Mouse)
UseTags6xHis and S-TagExpressionBacterialMutationdeletion of Cys2PromoterT7Available sinceNov. 18, 2016AvailabilityAcademic Institutions and Nonprofits only -
pDONR223 LC3C no-stop
Plasmid#123208PurposeGateway entry clone encoding human MAP1LC3C lacking stop codon, suitable for C-terminal taggingDepositorInsertMicrotubule-associated proteins 1A/1B light chain 3C (MAP1LC3C Human)
UseGateway entry vector / entry cloneTagsExpressionMutationStop codon removedPromoterCMVAvailable sinceMay 14, 2019AvailabilityAcademic Institutions and Nonprofits only -
FKBP-YPet-RanGAP*
Plasmid#175245PurposeBacterial expression and purification, SUMOylation substrate that can be recruited to FRB with rapamycin, Ypet is a FRET acceptor for CyPetDepositorInsertRANGAP1 (RANGAP1 Human)
UseTagsExpressionBacterialMutationAmino acid 562 F to APromotertacAvailable sinceOct. 18, 2021AvailabilityAcademic Institutions and Nonprofits only -
px330 MAU2 gRNA
Plasmid#165589PurposeInsertion of MAU2 degronDepositorInsertMAU2 (CTCF Mouse)
UseTagsExpressionMammalianMutationNAPromoterAvailable sinceMarch 12, 2021AvailabilityAcademic Institutions and Nonprofits only -
px330 CTCF gRNA
Plasmid#165588PurposeInsertion of CTCF degonDepositorInsertCTCF (CTCF Mouse)
UseTagsExpressionMammalianMutationNAPromoterAvailable sinceMarch 11, 2021AvailabilityAcademic Institutions and Nonprofits only -
GST-SF3B2 R508K aa 401-550 fragment
Plasmid#79674Purposebacterial expression of GST-SF3B2 fragment (401-550) with R508L methylation site mutationDepositorInsertsplicing factor 3b subunit 2 (SF3B2 Human)
UseTagsGSTExpressionBacterialMutationaa 451-550 with R508KPromotertacAvailable sinceJune 27, 2016AvailabilityAcademic Institutions and Nonprofits only -
MCU-mCherry
Plasmid#232790PurposeEncodes an mCherry-tagged MCU/Mitochondrial Calcium UniporterDepositorInsertCalcium uniporter protein, mitochondrial (MCU )
UseTagsmCherryExpressionMammalianMutationPromoterCMVAvailable sinceMarch 14, 2025AvailabilityAcademic Institutions and Nonprofits only -
pEGFP-N2-IFT20
Plasmid#218719PurposeExpresses C-terminally EGFP-tagged IFT20 in mammalian cellsDepositorInsertIFT20 (IFT20 Human)
UseTagsEGFPExpressionMammalianMutationPromoterCMVAvailable sinceJuly 30, 2024AvailabilityAcademic Institutions and Nonprofits only -
pROF366
Plasmid#155332PurposeExpression of FLuc under the control of AtAP1 promoterDepositorInsertPAtAP1-FLuc-TSV40
UseLuciferase and Synthetic BiologyTagsExpressionPlantMutationPromoterAvailable sinceOct. 26, 2023AvailabilityAcademic Institutions and Nonprofits only -
pMSCV puro PRDM14 ΔSET domain
Plasmid#193680PurposeConstitutive retroviral expression of PRDM14DepositorInsertPRDM14 (PRDM14 Human)
UseRetroviralTagsExpressionMutationDeletion of SET domainPromoterAvailable sinceJan. 3, 2023AvailabilityAcademic Institutions and Nonprofits only -
pMSCV puro PRDM14 ΔZinc finger domain
Plasmid#193679PurposeConstitutive retroviral expression of PRDM14DepositorInsertPRDM14 (PRDM14 Human)
UseRetroviralTagsExpressionMutationDeletion of Zinc finger domainPromoterAvailable sinceJan. 3, 2023AvailabilityAcademic Institutions and Nonprofits only -
EGFP-RanGAP*
Plasmid#175237PurposeBacterial expression and purification, low affinity SUMOylation substrate, point mutation F562A reduces affinity for E2, increasing the KmDepositorInsertRANGAP1 (RANGAP1 Human)
UseTagsExpressionBacterialMutationAmino acid 562 F to APromotertacAvailable sinceOct. 22, 2021AvailabilityAcademic Institutions and Nonprofits only -
FKBP-EGFP-RanGAP
Plasmid#175236PurposeBacterial expression and purification, high affinity SUMOylation substrate that can recruited to FRB with rapamycinDepositorInsertRANGAP1 (RANGAP1 Human)
UseTagsExpressionBacterialMutationPromotertacAvailable sinceOct. 18, 2021AvailabilityAcademic Institutions and Nonprofits only -
EGFP-SPN_ARR N52R (Shank3)
Plasmid#175255PurposeSPN-ARR fragment with structure opening N52R mutation in EGFP backbone for mammalian expressionDepositorInsertSPN-ARR fragment with N52R mutation from SHANK3
UseTagsExpressionMammalianMutationPromoterAvailable sinceOct. 7, 2021AvailabilityAcademic Institutions and Nonprofits only -
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pLV-H1-shScramble-hsynapsin-EGFP
Plasmid#220795Purposecontrol shRNA plasmid with EGFP expression in neuronsDepositorInsertEGFP
UseTagsExpressionMutationPromoterAvailable sinceOct. 17, 2024AvailabilityAcademic Institutions and Nonprofits only -
pLV-H1-shSRGAP2B/C#2-hsynapsin-EGFP
Plasmid#220797PurposeshRNA plasmid against human SRGAP2B/C genes (#2) with EGFP expression in neuronsDepositorInsertEGFP
UseTagsExpressionMutationPromoterAvailable sinceOct. 17, 2024AvailabilityAcademic Institutions and Nonprofits only -
pcDNA3-FLAG-MTOR-L1460P
Plasmid#69006Purposeactivating MTOR mutationDepositorInsertMTOR-L1460P (MTOR Human)
UseTagsFLAGExpressionMammalianMutationchange Leucine 1460 to ProlinePromoterAvailable sinceDec. 17, 2015AvailabilityAcademic Institutions and Nonprofits only -
pcDNA3-FLAG-MTOR-C1483F
Plasmid#69008Purposeactivating MTOR mutationDepositorInsertMTOR-C1483F (MTOR Human)
UseTagsFLAGExpressionMammalianMutationchange Cysteine 1483 to PhenylalaninePromoterAvailable sinceJan. 26, 2016AvailabilityAcademic Institutions and Nonprofits only -
MIC60-mCherry
Plasmid#232789PurposeEncodes an mCherry-tagged MIC60/IMMTDepositorInsertMICOS complex subunit MIC60 (IMMT Human)
UseTagsmCherryExpressionMammalianMutationPromoterCMVAvailable sinceMarch 13, 2025AvailabilityAcademic Institutions and Nonprofits only -
NC16 pCDNA3.1 FLAG NRF2
Plasmid#36971DepositorInsertNRF2 (NFE2L2 Human)
UseTagsFlagExpressionMammalianMutationPromoterCMVAvailable sinceJuly 10, 2012AvailabilityAcademic Institutions and Nonprofits only -
pLPC-FLAG.Mm.EPC2
Plasmid#184649PurposeRetroviral expression of mouse EPC2DepositorInsertEpc2 (Epc2 Mouse)
UseRetroviralTagsFLAGExpressionMammalianMutationPromoterCMVAvailable sinceJune 17, 2022AvailabilityAcademic Institutions and Nonprofits only -
pLPC-FLAG.Mm.EPC1
Plasmid#184648PurposeRetroviral expression of mouse EPC1DepositorInsertEPC1 (Epc1 Mouse)
UseRetroviralTagsFLAGExpressionMammalianMutationPromoterCMVAvailable sinceMay 24, 2022AvailabilityAcademic Institutions and Nonprofits only -
pLV-H1-shSRGAP2A-hsynapsin-EGFP
Plasmid#220798PurposeshRNA plasmid against human SRGAP2A gene with EGFP expression in neuronsDepositorInsertEGFP
UseTagsExpressionMutationPromoterAvailable sinceOct. 17, 2024AvailabilityAcademic Institutions and Nonprofits only -
pAcGFP-Hyg-CTCFdZnF-N1
Plasmid#131803PurposeExpresses the N and C terminus of human CTCF-GFP with the zinc finger domain removed in mammalian cellsDepositorInsertCTCF (CTCF Human)
UseTagsGFPExpressionMammalianMutationdeleted amino acids 1-1731PromoterAvailable sinceMay 3, 2022AvailabilityAcademic Institutions and Nonprofits only -
hRAP-pEZT-BM
Plasmid#177986PurposeExpression human RAP containing a C-terminal 6xHis tag in mammalian cellsDepositorInsertLDL receptor related protein associated protein 1 (LRPAP1 Human)
UseTags6xHisExpressionMammalianMutationPromoterCMVAvailable sinceDec. 10, 2021AvailabilityAcademic Institutions and Nonprofits only -
pCDNA-mSin1(1.1)-HA
Plasmid#73388PurposeExpresses mSin-HADepositorInsertmSin1 transcript variant protein isoform 1 (MAPKAP1 Human)
UseTagsHA tagExpressionMammalianMutationPromoterCMVAvailable sinceFeb. 24, 2016AvailabilityAcademic Institutions and Nonprofits only -
pcDNA5/FRT/TO V5 HSPA8
Plasmid#19514DepositorInsertheat shock 70kDa protein 8 (HSPA8 Human)
UseTagsV5ExpressionMammalianMutationPromoterAvailable sinceOct. 6, 2008AvailabilityAcademic Institutions and Nonprofits only -
pcDNA3-FLAG-MTOR-I2500F
Plasmid#69014Purposeactivating MTOR mutationDepositorInsertMTOR-I2500F (MTOR Human)
UseTagsFLAGExpressionMammalianMutationchange Isoleucine 2500 to PhenylalaninePromoterAvailable sinceDec. 16, 2015AvailabilityAcademic Institutions and Nonprofits only -
pLX317 TEAD2
Plasmid#193686PurposeConstitutive lentiviral expression of TEAD2DepositorInsertTEAD2 (TEAD2 Human)
UseLentiviralTagsExpressionMutationPromoterAvailable sinceDec. 20, 2022AvailabilityAcademic Institutions and Nonprofits only -
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pcDNA3-FLAG-MTOR-E1799K
Plasmid#69009Purposeactivating MTOR mutationDepositorInsertMTOR-E1799K (MTOR Human)
UseTagsFLAGExpressionMammalianMutationchange Glutamate 1799 to LysinePromoterAvailable sinceDec. 17, 2015AvailabilityAcademic Institutions and Nonprofits only -
YES1 Y537F
Plasmid#51299PurposeExpression of YES1 Y537FDepositorInsertYES1 (YES1 Human)
UseLentiviralTagsExpressionMutationY537FPromoterCMVAvailable sinceFeb. 13, 2014AvailabilityAcademic Institutions and Nonprofits only -
pcDNA3-FLAG-MTOR-R2505P
Plasmid#69015Purposeactivating MTOR mutationDepositorInsertMTOR-R2505P (MTOR Human)
UseTagsFLAGExpressionMammalianMutationchange Arginine 2505 to ProlinePromoterAvailable sinceDec. 16, 2015AvailabilityAcademic Institutions and Nonprofits only -
pLPC-FLAG.Mm.KAT5
Plasmid#184647PurposeRetroviral expression of mouse Kat5DepositorInsertKat5 (Kat5 Mouse)
UseRetroviralTagsFLAGExpressionMammalianMutationPromoterCMVAvailable sinceMay 24, 2022AvailabilityAcademic Institutions and Nonprofits only -
TCF4-DN in pLX303
Plasmid#42592DepositorInsertTCF7L2 (TCF7L2 Human)
UseLentiviralTagsExpressionMammalianMutation31 first amino acids of hTcf4 have been deletedPromoterCMVAvailable sinceFeb. 8, 2013AvailabilityAcademic Institutions and Nonprofits only -
pcDNA3-FLAG-MTOR-T1977R
Plasmid#69011Purposeactivating MTOR mutationDepositorInsertMTOR-T1977R (MTOR Human)
UseTagsFLAGExpressionMammalianMutationchange Threonine 1977 to ArgininePromoterAvailable sinceDec. 15, 2015AvailabilityAcademic Institutions and Nonprofits only -
pLKO.1 puro shSLC2A1-1
Plasmid#193702PurposeConstitutive lentiviral expression of SLC2A1 shRNADepositorInsertSLC2A1 (SLC2A1 Human)
UseLentiviralTagsExpressionMutationPromoterAvailable sinceDec. 19, 2022AvailabilityAcademic Institutions and Nonprofits only -
pLKO.1 puro shSLC2A1-2
Plasmid#193703PurposeConstitutive lentiviral expression of SLC2A1 shRNADepositorInsertSLC2A1 (SLC2A1 Human)
UseLentiviralTagsExpressionMutationPromoterAvailable sinceDec. 19, 2022AvailabilityAcademic Institutions and Nonprofits only -
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pcDNA3-FLAG-MTOR-F1888L
Plasmid#69010Purposeactivating MTOR mutationDepositorInsertMTOR-F1888L (MTOR Human)
UseTagsFLAGExpressionMammalianMutationchange Phenylalanine 1888 to LeucinePromoterAvailable sinceJan. 20, 2016AvailabilityAcademic Institutions and Nonprofits only -
pEGFP-C1-IFT27
Plasmid#218722PurposeExpresses N-terminally EGFP-tagged IFT27 in mammalian cellsDepositorInsertIFT27 (IFT27 Human)
UseTagsEGFPExpressionMammalianMutationPromoterCMVAvailable sinceMay 22, 2024AvailabilityAcademic Institutions and Nonprofits only -
pAcGFP-Hyg-CTCF-ZnF-N1
Plasmid#131802PurposeExpresses the [Zinc finger domain of human CTCF (a.a. 265-603)]-GFP in mammalian cellsDepositorInsertCTCF (CTCF Human)
UseTagsGFPExpressionMammalianMutationdeleted amino acids 1-1731PromoterAvailable sinceMay 3, 2022AvailabilityAcademic Institutions and Nonprofits only -
pORANGE Shank2-GFP KI
Plasmid#131496PurposeEndogenous tagging of Shank2: C-terminal (amino acid position: STOP codon)DepositorUseTagsExpressionMammalianMutationPromoterU6 and CbhAvailable sinceSept. 25, 2019AvailabilityAcademic Institutions and Nonprofits only -
TFORF3306
Plasmid#144782PurposeLentiviral vector for overexpressing transcription factor ORFs with unique 24-bp barcodes. Barcodes facilitate identification of transcription factors in pooled screens.DepositorInsertTHAP1 (THAP1 Human)
UseLentiviralTagsV5ExpressionMammalianMutationPromoterEF1aAvailable sinceAug. 14, 2023AvailabilityAcademic Institutions and Nonprofits only -
TFORF0146
Plasmid#142148PurposeLentiviral vector for overexpressing transcription factor ORFs with unique 24-bp barcodes. Barcodes facilitate identification of transcription factors in pooled screens.DepositorInsertTHAP1 (THAP1 Human)
UseLentiviralTagsExpressionMammalianMutationPromoterEF1aAvailable sinceJune 22, 2023AvailabilityAcademic Institutions and Nonprofits only -
pAcGFP-Hyg-CTCF-Cterm-N1
Plasmid#131801PurposeExpresses the [C-terminus of human CTCF (a.a. 577-728)]-GFP in mammalian cellsDepositorInsertCTCF (CTCF Human)
UseTagsGFPExpressionMammalianMutationdeleted amino acids 1-1731PromoterAvailable sinceMay 3, 2022AvailabilityAcademic Institutions and Nonprofits only -
pcDNA3-pmEMBer
Plasmid#174441PurposePlasma membrane-targeted ERK monobody binder for local inhibition of ERK activity in live cells.DepositorInsertpmEMBer
UseTags6xHIS - T7 tag (gene 10 leader) - Xpress (TM) tag…ExpressionMammalianMutationPromoterCMVAvailable sinceAug. 18, 2022AvailabilityAcademic Institutions and Nonprofits only -
pLPC-MYC.Mm.KAT5
Plasmid#184652PurposeRetroviral expression of mouse Kat5DepositorInsertKat5 (Kat5 Mouse)
UseRetroviralTagsMYCExpressionMammalianMutationPromoterCMVAvailable sinceMay 24, 2022AvailabilityAcademic Institutions and Nonprofits only