We narrowed to 1,284 results for: AP2;

1. pSLIK_hygro_BirA_CDKN1A

   Plasmid

   #136538

   Purpose

   Lentiviral expression vector for an inducible BirA-CDKN1A

   Depositor

   Kevin Janes

   Article

   Pereira et al Sci Signal. 2020 Apr 14;13(627). pii: 13

   Insert

   BirA-CDKN1A (CDKN1A )
   

   Use

   Lentiviral; Destinatioin vector for gateway cloni…

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Available since

   June 13, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

2. pEBG-MKK4-S255D/T259E (GST)

   Plasmid

   #21566

   Depositor

   Leonard Zon

   Article

   Sanchez et al Nature. . 372(6508):794-8.

   Insert

   mitogen-activated protein kinase kinase 4 (Map2k4 Mouse)
   

   Use

   Tags

   GST

   Expression

   Mammalian

   Mutation

   Serine 255 to Aspartic Acid, Threonine 259 to Gl…

   Promoter

   Available since

   July 17, 2009

   Availability

   Academic Institutions and Nonprofits only

3. MBP-MEK1 S218TAG

   Plasmid

   #68301

   Purpose

   N-terminal MBP tagged human MEK1 gene S218TAG for bacterial expression

   Depositor

   Jesse Rinehart

   Article

   Pirman et al Nat Commun. 2015 Sep 9;6:8130. doi: 10.1

   Insert

   MBP-MEK1 S218TAG (MAP2K1 Human, Synthetic)
   

   Use

   Tags

   His and MBP

   Expression

   Bacterial

   Mutation

   Promoter

   Available since

   Sept. 10, 2015

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

4. pEBG-MKK4-S255E/T259D (GST)

   Plasmid

   #21565

   Depositor

   Leonard Zon

   Article

   Sanchez et al Nature. . 372(6508):794-8.

   Insert

   mitogen-activated protein kinase kinase 4 (Map2k4 Mouse)
   

   Use

   Tags

   GST

   Expression

   Mammalian

   Mutation

   Serine 255 to Glutamic Acid, Threonine 259 to As…

   Promoter

   Available since

   July 22, 2009

   Availability

   Academic Institutions and Nonprofits only

5. TFORF2115

   Plasmid

   #144384

   Purpose

   Lentiviral vector for overexpressing transcription factor ORFs with unique 24-bp barcodes. Barcodes facilitate identification of transcription factors in pooled screens.

   Depositor

   Feng Zhang

   Article

   Joung et al Cell. 2023 Jan 5;186(1):209-229.e26. doi

   Insert

   NCOA6 (NCOA6 Human)
   

   Use

   Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   EF1a

   Available since

   Jan. 5, 2023

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

6. MTOR gRNA (BRDN0001147813)

   Plasmid

   #76783

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human MTOR

   Depositor

   David Root, John Doench

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   MTOR (MTOR Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   hU6

   Available since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

7. MTOR gRNA (BRDN0001145082)

   Plasmid

   #76782

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human MTOR

   Depositor

   David Root, John Doench

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   MTOR (MTOR Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   hU6

   Available since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

8. pGL-p21UTRm1&2

   Plasmid

   #20880

   Depositor

   Robert Blelloch

   Article

   Wang et al Nat Genet. 2008 Dec . 40(12):1478-83.

   Insert

   p21 3'UTR site 1 and 2 mutation (Cdkn1a Mouse)
   

   Use

   Luciferase

   Tags

   Expression

   Mammalian

   Mutation

   Predicted miRNA binding site 1 (Position ~420) GC…

   Promoter

   Available since

   Aug. 5, 2009

   Availability

   Academic Institutions and Nonprofits only

9. MTOR gRNA (BRDN0001145868)

   Plasmid

   #76784

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human MTOR

   Depositor

   David Root, John Doench

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   MTOR (MTOR Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   hU6

   Available since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

10. pcDNA3-HA p21 K161R, K163R

    Plasmid

    #78789

    Purpose

    To overexpress p21 K161R, K163R in Mammalian Cells

    Depositor

    Jaewhan Song

    Article

    Lee et al Cell Death Differ. 2013 Apr;20(4):620-9.

    Insert

    p21 (CDKN1A Human)
    

    Use

    Tags

    HA

    Expression

    Mammalian

    Mutation

    K161R, K163R_muation

    Promoter

    CMV

    Available since

    June 8, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

11. pCS3-MT-BX-6MYC p21

    Plasmid

    #78780

    Purpose

    To overexpress p21 in Mammalian Cells

    Depositor

    Jaewhan Song

    Article

    Lee et al Cell Death Differ. 2013 Apr;20(4):620-9.

    Insert

    p21 (CDKN1A Human)
    

    Use

    Tags

    6xMYC

    Expression

    Mammalian

    Mutation

    Promoter

    CMV IE94

    Available since

    June 8, 2016

    Availability

    Academic Institutions and Nonprofits only

12. pcDNA3-HA p21 K161Q, K163Q

    Plasmid

    #78790

    Purpose

    To overexpress p21 K161Q, K163Q in Mammalian Cells

    Depositor

    Jaewhan Song

    Article

    Lee et al Cell Death Differ. 2013 Apr;20(4):620-9.

    Insert

    p21 (CDKN1A Human)
    

    Use

    Tags

    HA

    Expression

    Mammalian

    Mutation

    K161Q, K163Q_muation

    Promoter

    CMV

    Available since

    June 8, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

13. pHH0103_GRB2-2/2

    Plasmid

    #91410

    Purpose

    Protein expression and purification of human SH3 domain construct GRB2-2/2

    Depositor

    Sachdev Sidhu

    Article

    Teyra et al Structure. 2017 Oct 3;25(10):1598-1610.e

    Insert

    GRB2-2/2 (GRB2 Human)
    

    Use

    Tags

    Expression

    Bacterial

    Mutation

    Promoter

    Available since

    March 19, 2018

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

14. His 3C Kinase dead MKK6 1-334

    Plasmid

    #87882

    Purpose

    E. coli expression of MKK6 kinase dead

    Depositor

    Peter Mace

    Article

    Weijman et al Proc Natl Acad Sci U S A. 2017 Mar 14;11

    Insert

    MKK6 (MAP2K6 Human)
    

    Use

    Tags

    3C protease site and 6xHis

    Expression

    Bacterial

    Mutation

    K82A, kinase dead mutant

    Promoter

    T7

    Available since

    March 29, 2017

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

15. pEN_TTmiRc2_BirA_CDKN1A

    Plasmid

    #136523

    Purpose

    Used as a donor vector to clone into pSLIK

    Depositor

    Kevin Janes

    Article

    Pereira et al Sci Signal. 2020 Apr 14;13(627). pii: 13

    Insert

    CDKN1A (CDKN1A Human)
    

    Use

    Entry vector for gateway cloning

    Tags

    Expression

    Mutation

    Promoter

    Available since

    July 28, 2021

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

16. pGEX Grb2-SH2 RK

    Plasmid

    #46441

    Depositor

    Bruce Mayer

    Article

    Machida et al Mol Cell. 2007 Jun 22;26(6):899-915.

    Insert

    Grb2 RK (GRB2 Human)
    

    Use

    Tags

    GST and PreScission

    Expression

    Bacterial

    Mutation

    contains amino acids 58-159

    Promoter

    Tac

    Available since

    July 10, 2013

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. EF1a_KLF12_P2A_Hygro_Barcode

    Plasmid

    #120498

    Purpose

    Barcoded lentiviral vector to express KLF12 in mammalian cells under control of EF1a promoter. Barcoded for transcript detection in single cell RNA-seq.

    Depositor

    Prashant Mali

    Article

    Parekh et al Cell Syst. 2018 Nov 12. pii: S2405-4712(

    Insert

    KLF12 (KLF12 Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    EF1a

    Available since

    Feb. 7, 2019

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. pLenti6/V5-DEST-ITGB3BP

    Plasmid

    #31211

    Depositor

    Lynda Chin

    Article

    Scott et al Cancer Cell. 2011 Jul 12;20(1):92-103.

    Insert

    ITGB3BP (ITGB3BP Human)
    

    Use

    Lentiviral

    Tags

    V5

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    July 29, 2011

    Availability

    Academic Institutions and Nonprofits only

19. pSLIK 3XFLAG-MKK7-EE-NLS hygro

    Plasmid

    #87780

    Purpose

    Inducible expression of constitutively active mutant MKK7 with a C-terminal NLS sequence

    Depositor

    Kevin Janes

    Article

    Shah et al Mol Cell Proteomics. 2017 Apr;16(4 suppl

    Insert

    MKK7 (Map2k7 Mouse)
    

    Use

    Lentiviral

    Tags

    3xFLAG and NLS

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    April 10, 2017

    Availability

    Academic Institutions and Nonprofits only

20. pCAG-p21_T145A/S146A

    Plasmid

    #42623

    Depositor

    Philipp Mergenthaler

    Article

    Mergenthaler et al J Cereb Blood Flow Metab. 2013 Mar;33(3)

    Insert

    p21 (CDKN1A Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    T145A/S146A

    Promoter

    CAG

    Available since

    March 7, 2013

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

21. pGEX6P1-HA-MEK5 CBM-E

    Plasmid

    #53168

    Purpose

    Expresses GST-HA tagged human MEK5 L280AH281AM323AQ332A from bacterial expression vector

    Depositor

    Christopher Counter

    Article

    Brady et al Nature. 2014 Apr 9. doi: 10.1038/nature1

    Insert

    MEK5 (MAP2K5 Human)
    

    Use

    Tags

    GST and HA

    Expression

    Bacterial

    Mutation

    L280A/H281A/M323A/Q332A

    Promoter

    Available since

    Sept. 29, 2014

    Availability

    Academic Institutions and Nonprofits only

22. pCDH-CMV-RFP-YAP (isoform 5)

    Plasmid

    #235690

    Purpose

    Express RFP tagged YAP gene in mammalian cells using the CMV promoter

    Depositor

    Duojia Pan

    Article

    Wang et al Cell. 2022 Nov 10;185(23):4376-4393.e18.

    Insert

    YAP (YAP1 Human)
    

    Use

    Lentiviral

    Tags

    RFP

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    April 30, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

23. pHSP90(G97D)-mOFP

    Plasmid

    #228195

    Purpose

    expressed human Hsp90 (G97D mutation) with a mOFP fluorescent protein tag

    Depositor

    Stephen Benkovic

    Article

    French et al Proc Natl Acad Sci U S A. 2013 Feb 12;11

    Insert

    HSP90AA1(G97D) (HSP90AA1 Human)
    

    Use

    Tags

    mOFP

    Expression

    Mammalian

    Mutation

    G97D mutation

    Promoter

    CMV

    Available since

    Dec. 13, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

24. pMSCV-FKBP-IRSp53(trunc C5)

    Plasmid

    #221277

    Purpose

    Expression of IRSp53 C-terminal truncation 5 (247-275) in mammalian cells by retroviral transduction

    Depositor

    Jonathan Kagan

    Article

    Landau et al Mol Cell. 2024 Jul 11;84(13):2436-2454.e

    Insert

    IRSp53 C-terminal truncation 5 (247-275) (Baiap2 Mouse)
    

    Use

    Retroviral

    Tags

    3xFLAG-4xFKBP

    Expression

    Mutation

    Promoter

    Available since

    July 17, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

25. pMSCV-FKBP-IRSp53(trunc C4)

    Plasmid

    #221276

    Purpose

    Expression of IRSp53 C-terminal truncation 4 (247-295) in mammalian cells by retroviral transduction

    Depositor

    Jonathan Kagan

    Article

    Landau et al Mol Cell. 2024 Jul 11;84(13):2436-2454.e

    Insert

    IRSp53 C-terminal truncation 4 (247-295) (Baiap2 Mouse)
    

    Use

    Retroviral

    Tags

    FLAG-4xFKBP

    Expression

    Mutation

    Promoter

    Available since

    July 17, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

26. pMSCV-FKBP-IRSp53(trunc C2)

    Plasmid

    #221274

    Purpose

    Expression of IRSp53 C-terminal truncation 2 (247-335) in mammalian cells by retroviral transduction

    Depositor

    Jonathan Kagan

    Article

    Landau et al Mol Cell. 2024 Jul 11;84(13):2436-2454.e

    Insert

    IRSp53 C-terminal truncation 2 (247-335) (Baiap2 Mouse)
    

    Use

    Retroviral

    Tags

    3xFLAG-4xFKBP

    Expression

    Mutation

    Promoter

    Available since

    July 17, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

27. pMSCV-FKBP-IRSp53(trunc C1)

    Plasmid

    #221273

    Purpose

    Expression of IRSp53 C-terminal truncation 1 (247-355) in mammalian cells by retroviral transduction

    Depositor

    Jonathan Kagan

    Article

    Landau et al Mol Cell. 2024 Jul 11;84(13):2436-2454.e

    Insert

    IRSp53 C-terminal truncation 1 (247-355) (Baiap2 Mouse)
    

    Use

    Retroviral

    Tags

    3xFLAG-4xFKBP

    Expression

    Mutation

    Promoter

    Available since

    July 17, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

28. pRetroX-TRE3G-IRSp53 P278D P281D

    Plasmid

    #221320

    Purpose

    Dox-inducible expression of IRSp53 mutant in mammalian cells by retroviral transduction

    Depositor

    Jonathan Kagan

    Article

    Landau et al Mol Cell. 2024 Jul 11;84(13):2436-2454.e

    Insert

    IRSp53 (Baiap2 Mouse)
    

    Use

    Retroviral

    Tags

    3xFLAG

    Expression

    Mutation

    P278D P281D

    Promoter

    TRE3G

    Available since

    July 16, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

29. pMSCV-FKBP-IRSp53(trunc N1)

    Plasmid

    #221272

    Purpose

    Expression of IRSp53 N-terminal truncation 1 (257-375) in mammalian cells by retroviral transduction

    Depositor

    Jonathan Kagan

    Article

    Landau et al Mol Cell. 2024 Jul 11;84(13):2436-2454.e

    Insert

    IRSp53 N-terminal truncation 1 (257-375) (Baiap2 Mouse)
    

    Use

    Retroviral

    Tags

    FLAG-4xFKBP

    Expression

    Mutation

    Promoter

    Available since

    July 15, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

30. pMSCV-FKBP-IRSp53(pLxIS)

    Plasmid

    #221268

    Purpose

    Expression of IRSp53 pLxIS (247-375) in mammalian cells by retroviral transduction

    Depositor

    Jonathan Kagan

    Article

    Landau et al Mol Cell. 2024 Jul 11;84(13):2436-2454.e

    Insert

    IRSp53 pLxIS (247-375) (Baiap2 Mouse)
    

    Use

    Retroviral

    Tags

    3xFLAG-4xFKBP

    Expression

    Mutation

    Promoter

    Available since

    July 10, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

31. pMSCV-FKBP-IRSp53(pLxIS) S269A

    Plasmid

    #221269

    Purpose

    Expression of IRSp53 pLxIS mutant in mammalian cells by retroviral transduction

    Depositor

    Jonathan Kagan

    Article

    Landau et al Mol Cell. 2024 Jul 11;84(13):2436-2454.e

    Insert

    IRSp53 pLxIS (Baiap2 Mouse)
    

    Use

    Retroviral

    Tags

    3xFLAG-4xFKBP

    Expression

    Mutation

    S269A

    Promoter

    Available since

    July 10, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

32. pCDNA3-SREBP-1 (A317-318)

    Plasmid

    #204193

    Purpose

    Mammalian expression of SREBP-1 (isoform 1)

    Depositor

    Allan Weissman

    Article

    Yang et al J Biol Chem. 2023 Oct 12;299(12):105346.

    Insert

    SREBP-1 (SREBF1 Human)
    

    Use

    Tags

    E-tag and T7x2

    Expression

    Mammalian

    Mutation

    Gly to Ala 317, 318

    Promoter

    Available since

    April 8, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

33. pCDNA3-SREBP-1 (A317-318; A341)

    Plasmid

    #204194

    Purpose

    Mammalian expression of SREBP-1 (Isoform 1)

    Depositor

    Allan Weissman

    Article

    Yang et al J Biol Chem. 2023 Oct 12;299(12):105346.

    Insert

    SREBP-1 (SREBF1 Human)
    

    Use

    Tags

    E-tag and T7x2

    Expression

    Mammalian

    Mutation

    Gly to Ala 317,318,341

    Promoter

    Available since

    April 8, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

34. pCDNA3- SREBP-1 (A317-318; L340)

    Plasmid

    #204195

    Purpose

    Mammalian expression of SREBP-1 (Isoform 1)

    Depositor

    Allan Weissman

    Article

    Yang et al J Biol Chem. 2023 Oct 12;299(12):105346.

    Insert

    SREBP-1 (SREBF1 Human)
    

    Use

    Tags

    E-tag and T7x2

    Expression

    Mammalian

    Mutation

    Gly to Ala 317,318; Gly to Leu 340

    Promoter

    Available since

    April 8, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

35. pCDNA3- SREBP-1 (A317-318;A341; A1171)

    Plasmid

    #204196

    Purpose

    Mammalian expression of SREBP-1 (isoform 1)

    Depositor

    Allan Weissman

    Article

    Yang et al J Biol Chem. 2023 Oct 12;299(12):105346.

    Insert

    SREBP-1 (SREBF1 Human)
    

    Use

    Tags

    E-tag and T7x2

    Expression

    Mammalian

    Mutation

    Gly to Ala 317,318,341,1171

    Promoter

    Available since

    April 8, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

36. pCDNA3-SREBP-1 (A341; A1171)

    Plasmid

    #204197

    Purpose

    Mammalian expression of SREBP-1 (isoform 1)

    Depositor

    Allan Weissman

    Article

    Yang et al J Biol Chem. 2023 Oct 12;299(12):105346.

    Insert

    SREBP-1a (SREBF1 Human)
    

    Use

    Tags

    E-tag and T7x2

    Expression

    Mammalian

    Mutation

    Gly to Ala 341, 1171

    Promoter

    Available since

    April 8, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

37. pLKO-Tet-On shYAP1-6

    Plasmid

    #193667

    Purpose

    Tet inducible knockdown of YAP1

    Depositor

    William Hahn

    Article

    Kim et al Dev Cell. 2022 Jan 24;57(2):212-227.e8.

    Insert

    YAP1 (YAP1 Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    Available since

    Dec. 20, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

38. pLKO-Tet-On shYAP1-2

    Plasmid

    #193665

    Purpose

    Tet inducible knockdown of YAP1

    Depositor

    William Hahn

    Article

    Kim et al Dev Cell. 2022 Jan 24;57(2):212-227.e8.

    Insert

    YAP1 (YAP1 Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    Available since

    Dec. 20, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

39. pLKO.1 puro shYAP1-2

    Plasmid

    #193693

    Purpose

    Constitutive lentiviral expression of YAP1 shRNA

    Depositor

    William Hahn

    Article

    Kim et al Dev Cell. 2022 Jan 24;57(2):212-227.e8.

    Insert

    YAP1 (YAP1 Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    Available since

    Dec. 19, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

40. Lenti-sgStag2#1/Cre

    Plasmid

    #173659

    Purpose

    Expresses a Stag2-targeting gRNA and Cre-recombinase

    Depositor

    Charles Swanton

    Article

    Cai et al Cancer Discov. 2021 Feb 19. pii: 2159-82

    Insert

    gRNA targeting Stag2 (Stag2 Mouse)
    

    Use

    CRISPR, Cre/Lox, and Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    Available since

    May 17, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge