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We narrowed to 5,553 results for: pcDNA3.1+

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Showing: 1701 - 1750 of 5553 results

  1. pcDNA3.1-KIT-D816V-V5/HIS

    Plasmid
    #236010
    Purpose
    expression of the D816V kinase defective mutant variant of human KIT that is associated with Acute Myeloid Leukemia and MASTSYS
    Depositor
    Pavel Krejčí
    Article
    Gudernova et al Elife. 2017 Feb 15;6. pii: e21536. doi:
    Insert
    human KIT-D816V receptor tyrosine kinase, full length (KIT Human)
    Tags
    V5/His
    Expression
    Mammalian
    Mutation
    D816V substitution
    Promoter
    CMV
    Available Since
    May 27, 2026
    Availability
    Academic Institutions and Nonprofits only
    236010-plasmid-map-sequence-id-511408

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  3. pcDNA3.1-Gαi1-Gβ1-Gγ2

    Plasmid
    #254720
    Purpose
    Expresses G protein heterotrimer with Gαi1, Gβ1 and Gγ2 ('dark'). Vector used as control for G protein recruitment or 'nuc-BRET' assay. Based on TRUPATH Triple Gαi1 (#196048).
    Depositor
    Cornelius Gati
    Article
    Khan et al Nature. 2025 Dec;648(8094):755-763. doi:
    Inserts
    Gαi1 (GNAI1 Human)
    Gβ1 (GNB1 Human)
    Gγ2 (GNG2 Human)
    Expression
    Mammalian
    Promoter
    CMV, IRES, and T2A
    Available Since
    May 12, 2026
    Availability
    Academic Institutions and Nonprofits only
    254720-plasmid-map-sequence-id-509987

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  4. pcDNA3.1-Gαi1ΔF-Gβ1-Gγ2

    Plasmid
    #254721
    Purpose
    Expresses G protein heterotrimer with Gαi1-ΔF, Gβ1 and Gγ2-GFP2 fusion as negative control. Vector used as controlfor G protein recruitment or 'nuc-BRET' assay. Based on TRUPATH Triple Gαi1 (#196048).
    Depositor
    Cornelius Gati
    Article
    Khan et al Nature. 2025 Dec;648(8094):755-763. doi:
    Inserts
    Gαi1 (GNAI1 Human)
    Gβ1 (GNB1 Human)
    Gγ2 (GNG2 Human)
    Tags
    GFP2
    Expression
    Mammalian
    Mutation
    deleted C-terminal amino acid F264
    Promoter
    CMV, IRES, and T2A
    Available Since
    May 12, 2026
    Availability
    Academic Institutions and Nonprofits only
    254721-plasmid-map-sequence-id-509983

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  7. pcDNA3.1-Gαz Q205L-YFP

    Plasmid
    #250702
    Purpose
    Expressing Citrine version of YFP fused human Gαz Q205L
    Depositor
    Mikel Garcia-Marcos
    Insert
    G_z Q205L-YFP
    Expression
    Mammalian
    Mutation
    Q205L in G_z sequence
    Promoter
    CMV
    Available Since
    April 22, 2026
    Availability
    Academic Institutions and Nonprofits only
    250702-plasmid-map-sequence-id-507426

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  8. pcDNA3.1-Gαs R201C (short)

    Plasmid
    #250708
    Purpose
    Expressing human Gαs R201C mutant, short isoform
    Depositor
    Mikel Garcia-Marcos
    Insert
    G_s R201C (short isoform)
    Expression
    Mammalian
    Mutation
    R201C in G_s sequence
    Promoter
    CMV
    Available Since
    March 3, 2026
    Availability
    Academic Institutions and Nonprofits only
    250708-plasmid-map-sequence-id-501629

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  9. pcDNA3.1-Gαs S275L (short)

    Plasmid
    #250710
    Purpose
    Expressing human Gαs S275L mutant, short isoform
    Depositor
    Mikel Garcia-Marcos
    Insert
    G_s S275L (short isoform)
    Expression
    Mammalian
    Mutation
    S275L in G_s sequence
    Promoter
    CMV
    Available Since
    March 2, 2026
    Availability
    Academic Institutions and Nonprofits only
    250710-plasmid-map-sequence-id-501490

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  10. pcDNA3.1-Gαs Q227L (short)

    Plasmid
    #250709
    Purpose
    Expressing human Gαs Q227L mutant, short isoform
    Depositor
    Mikel Garcia-Marcos
    Insert
    G_s Q227L (short isoform)
    Expression
    Mammalian
    Mutation
    Q227L in G_s sequence
    Promoter
    CMV
    Available Since
    March 2, 2026
    Availability
    Academic Institutions and Nonprofits only
    250709-plasmid-map-sequence-id-501481

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  20. pcDNA3.1(+)_Nav1.6(K1425TAG, Y371C)-HA

    Plasmid
    #239766
    Purpose
    Expresses TTX-resistant (Y371C) variant of mouse Nav1.6 with a TAG codon at position 1425 and a C-terminal HA tag in mammalian cells. Can be used for click labeling.
    Depositor
    Ivana Nikić-Spiegel
    Article
    Stajkovic et al J Cell Sci. 2023 Jun 15;136(12):jcs26060
    Insert
    Scn8a (Scn8a Mouse)
    Tags
    HA-tag
    Expression
    Mammalian
    Mutation
    K1425TAG, Y371C
    Promoter
    CMV
    Available Since
    July 14, 2025
    Availability
    Academic Institutions and Nonprofits only
    239766-plasmid-map-sequence-id-477737

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  21. pcDNA3.1(+)_Nav1.6(K1546TAG, Y371C)-HA

    Plasmid
    #239767
    Purpose
    Expresses TTX-resistant (Y371C) variant of mouse Nav1.6 with a TAG codon at position 1546 and a C-terminal HA tag in mammalian cells. Can be used for click labeling.
    Depositor
    Ivana Nikić-Spiegel
    Article
    Stajkovic et al J Cell Sci. 2023 Jun 15;136(12):jcs26060
    Insert
    Scn8a (Scn8a Mouse)
    Tags
    HA-tag
    Expression
    Mammalian
    Mutation
    K1546TAG, Y371C
    Promoter
    CMV
    Available Since
    July 14, 2025
    Availability
    Academic Institutions and Nonprofits only
    239767-plasmid-map-sequence-id-477107

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  23. pcDNA3.1-IARS2-H112A/P115A

    Plasmid
    #232338
    Purpose
    Expresses human IARS2 with putative isoleucine binding deficiency mutations (H112A and P115A) in mammalian cells, also carrying synonymous mutations described in Addgene #232340
    Depositor
    Quanfu Ma
    Insert
    IARS2 (IARS2 Human)
    Expression
    Mammalian
    Mutation
    Putative isoleucine binding deficiency mutation H…
    Promoter
    CMV
    Available Since
    June 9, 2025
    Availability
    Academic Institutions and Nonprofits only
    232338-plasmid-map-sequence-id-474537

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  24. pcDNA3.1-IARS2-K664A/K667A

    Plasmid
    #232339
    Purpose
    Expresses human IARS2 with putative tRNA binding deficiency mutations (K664A and K667A) in mammalian cells, also carrying synonymous mutations described in Addgene #232340
    Depositor
    Quanfu Ma
    Insert
    IARS2 (IARS2 Human)
    Expression
    Mammalian
    Mutation
    Putative tRNA binding deficiency mutation K664A A…
    Promoter
    CMV
    Available Since
    June 9, 2025
    Availability
    Academic Institutions and Nonprofits only
    232339-plasmid-map-sequence-id-474533

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  26. pcDNA3.1-PDGFRA-V561D-V5/HIS

    Plasmid
    #234762
    Purpose
    Expression of the V561D mutant variant of human PDGFRA, which is associated with Gastrointestinal Stromal Tumor and GIST-Plus Syndrome, , constantly activated
    Depositor
    Pavel Krejčí
    Article
    Gudernova et al Oncotarget. 2017 Nov 27;8(65):109319-109
    Insert
    PDGFRA-V561D receptor tyrosine kinase, full length (PDGFRA Human)
    Tags
    V5/His
    Expression
    Mammalian
    Mutation
    V561D substitution
    Promoter
    CMV
    Available Since
    April 15, 2025
    Availability
    Academic Institutions and Nonprofits only
    234762-plasmid-map-sequence-id-468956

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  28. pcDNA3.1-PDGFRA-R487L-V5/HIS

    Plasmid
    #234761
    Purpose
    Expression of the R487L mutant variant of human PDGFRA, which might be associated with Gastrointestinal Stromal Tumor
    Depositor
    Pavel Krejčí
    Article
    Gudernova et al Elife. 2017 Feb 15;6. pii: e21536. doi:
    Insert
    PDGFRA-R487L receptor tyrosine kinase, full length (PDGFRA Human)
    Tags
    V5/His
    Expression
    Mammalian
    Mutation
    R487L substitution
    Promoter
    CMV
    Available Since
    April 15, 2025
    Availability
    Academic Institutions and Nonprofits only
    234761-plasmid-map-sequence-id-468953

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  29. pcDNA3.1-PDGFRA-D842V-V5/HIS

    Plasmid
    #234763
    Purpose
    Expression of the D842V mutant variant of human PDGFRA, which is associated with Gastrointestinal Stromal Tumor, constantly activated
    Depositor
    Pavel Krejčí
    Article
    Gudernova et al Oncotarget. 2017 Nov 27;8(65):109319-109
    Insert
    PDGFRA-D842V receptor tyrosine kinase, full length (PDGFRA Human)
    Tags
    V5/His
    Expression
    Mammalian
    Mutation
    D842V substitution
    Promoter
    CMV
    Available Since
    April 15, 2025
    Availability
    Academic Institutions and Nonprofits only
    234763-plasmid-map-sequence-id-468952

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  31. pcDNA3.1-PDGFRA-T674I-V5/HIS

    Plasmid
    #234756
    Purpose
    Expression of the T674I mutant variant of human PDGFRA, which is associated with Idiopathic Hypereosinophilic Syndrome, resistant to imatinib
    Depositor
    Pavel Krejčí
    Article
    Gudernova et al Elife. 2017 Feb 15;6. pii: e21536. doi:
    Insert
    PDGFRA-T674I receptor tyrosine kinase, full length (PDGFRA Human)
    Tags
    V5/His
    Expression
    Mammalian
    Mutation
    T674I substitution
    Promoter
    CMV
    Available Since
    April 14, 2025
    Availability
    Academic Institutions and Nonprofits only
    234756-plasmid-map-sequence-id-468865

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  32. YFP Rab11 Q70L in pcDNA3.1

    Plasmid
    #90467
    Purpose
    RhoA mediated cell migration
    Depositor
    Narasimhan Gautam
    Insert
    Rab11 Q70L
    Tags
    mEYFP
    Expression
    Mammalian
    Promoter
    CMV
    Available Since
    April 1, 2025
    Availability
    Academic Institutions and Nonprofits only
    90467-plasmid-map-sequence-id-197844

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Showing: 1701 - 1750 of 5553 results