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Plasmid#22273DepositorInsertSV40 Large T antigen K1 mutant (SV40gp6 )
UseRetroviralTagsExpressionMammalianMutationE107K (K1 mutation)PromoterAvailable sinceFeb. 17, 2010AvailabilityAcademic Institutions and Nonprofits only -
pIS1 DICER1 long-mut-miR103/107
Plasmid#21652DepositorInsertDicer 1 (DICER1 Human)
UseLuciferaseTagsLuciferaseExpressionMammalianMutationMutant miR103/107 microRNA binding sitesPromoterAvailable sinceJuly 22, 2009AvailabilityAcademic Institutions and Nonprofits only -
CMVTO-nTVMVP-AP4-tevs-P3-tevs-cTVMVPmut
Plasmid#179660PurposeCytosolic TEVP-inducible caged-nTVMVPDepositorInsertCaged-nTVMVP
UseTagsExpressionMammalianMutationPromoterAvailable sinceMarch 23, 2022AvailabilityAcademic Institutions and Nonprofits only -
CMVTO-nTVMVPmut-tevs-AP4-tevs-P3-cTVMVP
Plasmid#179661PurposeCytosolic TEVP-inducible caged-cTVMVPDepositorInsertCaged-cTVMVP
UseTagsExpressionMammalianMutationPromoterAvailable sinceMarch 23, 2022AvailabilityAcademic Institutions and Nonprofits only -
pPB-CAG-mNanog-mut-pgk-hph
Plasmid#74914PurposeMammalian expression of mNanog (Y42E, K43T)DepositorInsertNanog (Nanog Mouse)
UseTagsExpressionMammalianMutationK43T of Nanog protein and Y42E of Nanog homeodoma…PromoterCAGAvailable sinceMay 17, 2016AvailabilityAcademic Institutions and Nonprofits only -
pmyc-GFP-TNRC6A-NLS/NES-mut
Plasmid#42002DepositorInsertTNRC6A (TNRC6A Human)
UseTagsEGFP and MycExpressionMammalianMutationR930A, R931A, R932A, R934A, F951A, F955A, I958A, …PromoterCMVAvailable sinceMarch 4, 2013AvailabilityAcademic Institutions and Nonprofits only -
pcDNA4-TO-myc-His Trask [YdeltaF] mutant
Plasmid#31769DepositorInsertTrask (CDCP1 Human)
UseTagsHis and MycExpressionMammalianMutationY707/734/743FPromoterCMVAvailable sinceSept. 19, 2011AvailabilityAcademic Institutions and Nonprofits only -
pET21 Catalytic Domain of MALT1 Catalytic Mutant
Plasmid#48971PurposeExpresses catalytic domain of MALT1 catalytic mutant in e.coli AA 329-566DepositorInsertMALT1 (MALT1 Human)
UseTagsHisExpressionBacterialMutationContains AA 329-566; Catalytic Mutant C464APromoterT7Available sinceOct. 23, 2013AvailabilityAcademic Institutions and Nonprofits only -
pGL3-DICER-Prom Ebox double mut
Plasmid#25854DepositorInsertDICER-Promoter Ebox double mut (DICER1 gene ID 23405, Human)
UseLuciferaseTagsExpressionMammalianMutationPromoterAvailable sinceAug. 25, 2010AvailabilityAcademic Institutions and Nonprofits only -
LB1461 (Bcl-2 promoter with MHS1234, NFkB mut)
Plasmid#15385DepositorInsertB-cell lymphoma/leukemia-2 (BCL2 Human)
UseLuciferaseTagsLuciferaseExpressionBacterial and MammalianMutationBcl-2 full promoter with IgH full enhancer MHS123…PromoterAvailable sinceAug. 1, 2007AvailabilityAcademic Institutions and Nonprofits only -
pcDNA4/HisMaxB-YAP2-1st&2nd WW mutant
Plasmid#19000DepositorInsertYes-kinase associated protein (YAP1 Human)
UseTagsHisExpressionMammalianMutationTryptophan 199 changed to Alanine, and Proline 2…PromoterAvailable sinceSept. 8, 2008AvailabilityAcademic Institutions and Nonprofits only -
pMiR-E6AP-3'UTR-miR-375-mut
Plasmid#53695PurposeLuciferase reporter assay for E6AP 3'UTR with point mutation on miR-375 binding siteDepositorInsertUBE3A 3'UTR (UBE3A Human)
UseLuciferaseTagsExpressionMutationMutation on miR-375 binding site on E6AP 3'U…PromoterAvailable sinceJuly 2, 2014AvailabilityAcademic Institutions and Nonprofits only -
pGL3-DICER-Prom upstream Ebox Mut
Plasmid#25852DepositorInsertDICER-Promoter upstream Ebox Mut (DICER1 gene ID 23405, Human)
UseLuciferaseTagsExpressionMammalianMutationPromoterAvailable sinceAug. 25, 2010AvailabilityAcademic Institutions and Nonprofits only -
Fibronectin-human-mutated N-terminal (N), V1 and V2 Glycosylation sites
Plasmid#120407Purposeenables eukaryotic expression of human plasma fibronectin in which all three O-glycosylation sites were mutated from threonine to serineDepositorInsertFibronectin (FN1 Human)
UseTagsExpressionMammalianMutationContains complete variable region with mutations …PromoterCMVAvailable sinceJan. 23, 2019AvailabilityAcademic Institutions and Nonprofits only -
pGL3-DICER-Prom downstream Ebox Mut
Plasmid#25853DepositorInsertDICER-Prom downstream Ebox Mut (DICER1 gene ID 23405, Human)
UseLuciferaseTagsExpressionMammalianMutationPromoterAvailable sinceAug. 25, 2010AvailabilityAcademic Institutions and Nonprofits only -
pRS416-PHO5-GFP-2xOsh2 PH domain EE mutation
Plasmid#58830PurposeExpresses GFP-Tagged and mutated Osh2 PH domain in yeastDepositorInsert2 x Osh2 PH domain (OSH2 Budding Yeast)
UseTagsGFP and MycExpressionYeastMutationchanged Lysine 307 to Glutamate and Arginine 309 …PromoterPHO5Available sinceSept. 30, 2014AvailabilityAcademic Institutions and Nonprofits only -
FLAG-ADA add back mutant pCMV5
Plasmid#17554DepositorInsertFLAG-FoxO1-ADA
UseTagsFLAGExpressionMammalianMutationsiRNA-resistant Foxo1 by replacing 3 residues (un…PromoterAvailable sinceOct. 17, 2008AvailabilityAcademic Institutions and Nonprofits only -
pGL3-Basic-Fascin-Promoter 402 mutation
Plasmid#89825PurposeFascin promoter for luciferase assayDepositorInsertFascin1 (FSCN1 Human)
UseLuciferaseTagsExpressionMutation-370 Smad binding element mutated from CAGAC to T…PromoterSV40Available sinceJuly 5, 2017AvailabilityAcademic Institutions and Nonprofits only -
Stx3 triple mutant (F31A D33A E34A)
Plasmid#86945PurposeExpresses human Stx3 with triple mutation in the apical targeting signal (F31A D33A E34A)DepositorInsertSTX3 triple mutant (F31A D33A E34A) (STX3 Human)
UseTagsmyc-His6ExpressionMammalianMutationtriple mutant (F31A D33A E34A)PromoterAvailable sinceMarch 17, 2017AvailabilityAcademic Institutions and Nonprofits only -
CJ40 (let-7 seed mutant perfect site)
Plasmid#17773DepositorInsertlet-7 seed mutant perfect site (let-7 Fly)
UseLuciferase; Drosophila metallothionein gene promo…Tagsrenilla luciferaseExpressionInsectMutationseed mutantPromoterAvailable sinceApril 15, 2008AvailabilityAcademic Institutions and Nonprofits only -
pRS406-PHO5-GFP-CERT PH domain EE mutation
Plasmid#58833PurposeExpresses GFP-Tagged and mutated CERT PH domain in yeastDepositorInsertcollagen, type IV, alpha 3 binding protein PH domain (CERT1 Human)
UseTagsGFP and MycExpressionYeastMutationchanged Arginine 43 to GlutamatePromoterPHO5Available sinceAug. 27, 2014AvailabilityAcademic Institutions and Nonprofits only -
CMV-FFluc-GPD1L-3'UTR Full mut
Plasmid#32489DepositorInsertGPD1L 3'UTR (Gpd1l Mouse)
UseTagsLuciferaseExpressionMammalianMutationMutated in the entire miR-210 binding regionPromoterCMVAvailable sinceNov. 4, 2011AvailabilityAcademic Institutions and Nonprofits only -
CMV-FFluc-GPD1L-3'UTR Seed Mut
Plasmid#32490DepositorInsertGPD1L 3'UTR (Gpd1l Mouse)
UseLuciferaseTagsLuciferaseExpressionMammalianMutationPromoterCMVAvailable sinceNov. 2, 2011AvailabilityAcademic Institutions and Nonprofits only -
LB1554 (Bcl-2 promoter with MHS1234, Cdx mut)
Plasmid#15384DepositorInsertB-cell lymphoma/leukemia-2 (BCL2 Human)
UseLuciferaseTagsLuciferaseExpressionBacterial and MammalianMutationBcl-2 full promoter with IgH full enhancer MHS123…PromoterAvailable sinceAug. 1, 2007AvailabilityAcademic Institutions and Nonprofits only -
pDisplay-GRAB-HaloDAmut-IRES-EGFP-CAAX
Plasmid#234411PurposeExpresses the chemigenetic dopamine (DA) control sensor GRAB_HaloDAmut and a membrane-localized EGFP in mammalian cellsDepositorInsertGPCR activation based chemigenetic dopamine (DA) control sensor GRAB_HaloDAmut
UseTagsExpressionMammalianMutationPromoterCMVAvailable sinceJune 2, 2025AvailabilityAcademic Institutions and Nonprofits only -
pCDH-3_Flag-YTHDF2 (nonsense mutation of sgYTHDF2-1)
Plasmid#232945PurposeExpresses YTHDF2 with synonymous mutations rendering it resistant to sgYTHDF2-1-mediated knockdownDepositorInsertYTHDF2 (YTHDF2 Human)
UseLentiviralTagsExpressionMutationsynonymous mutationPromoterAvailable sinceMay 16, 2025AvailabilityAcademic Institutions and Nonprofits only -
pAAV-hSyn-FLAG-HA-T6B-MUT-YFP
Plasmid#235140PurposeExpresses the mutant T6B peptide fused with YFP under the human synapsin promoterDepositorInsertmutant T6B peptide
UseAAVTagsFLAG/HAExpressionMutation5 tryptophan residues of T6B-WT mutatedPromoterhSynAvailable sinceApril 23, 2025AvailabilityAcademic Institutions and Nonprofits only -
1203AE-CMV-Cas7.1-7.2-H43A-mutant
Plasmid#221449PurposeEffector expresses Cas7.1, Linker1, Cas11, Linker 2, and deactivated Cas7.2 domains from DiCas7-11, H to A mutation at amino acid 43 in Cas7.1DepositorInsertTruncated DiCas7-11
UseCRISPRTagsExpressionMammalianMutationPromoterAvailable sinceFeb. 19, 2025AvailabilityAcademic Institutions and Nonprofits only -
1203AF-CMV-Cas7.1-7.2-Y55A-mutant
Plasmid#221450PurposeEffector expresses Cas7.1, Linker1, Cas11, Linker 2, and deactivated Cas7.2 domains from DiCas7-11, Y to A mutation at amino acid 55 in Cas7.1DepositorInsertTruncated DiCas7-11
UseCRISPRTagsExpressionMammalianMutationPromoterAvailable sinceFeb. 19, 2025AvailabilityAcademic Institutions and Nonprofits only -
1203AG-CMV-Cas7.1-7.2-N152A-mutant
Plasmid#221451PurposeEffector expresses Cas7.1, Linker1, Cas11, Linker 2, and deactivated Cas7.2 domains from DiCas7-11, N to A mutation at amino acid 152 in Cas7.1DepositorInsertTruncated DiCas7-11
UseCRISPRTagsExpressionMammalianMutationPromoterAvailable sinceFeb. 19, 2025AvailabilityAcademic Institutions and Nonprofits only