We narrowed to 29,389 results for: des.2

1. pLG1-puro-sgATL1-2

   Plasmid

   #109006

   Purpose

   CRISPRi knockdown of targeted gene (to be used with Addgene #102244 or other dCas9-KRAB constructs)

   Depositor

   Jacob Corn

   Article

   Liang et al J Cell Biol. 2018 Aug 24. pii: jcb.20180

   Insert

   ATL1-sgRNA #2 (ATL1 Human)
   

   Use

   Lentiviral

   Expression

   Mammalian

   Promoter

   mU6 promoter

   Available Since

   Aug. 22, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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2. pSicoR (EGFP) shPnky-2

   Plasmid

   #79142

   Purpose

   Stable expression of shRNA targeting mouse Pnky. The shRNA (and EGFP) can be excised by the addition of Cre

   Depositor

   Daniel Lim

   Article

   Ramos et al Cell Stem Cell. 2015 Apr 2;16(4):439-47.

   Insert

   shPnky-2 (Gm30731 Mouse)
   

   Use

   Cre/Lox, Lentiviral, and RNAi

   Expression

   Mammalian

   Promoter

   U6 for the shRNA and CMV for EGFP

   Available Since

   June 29, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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3. lentiCRISPR v2 sgKEAP1-2

   Plasmid

   #186459

   Purpose

   knock out KEAP1 in mammalian cells

   Depositor

   Boyi Gan

   Article

   Koppula et al Nat Commun. 2022 Apr 22;13(1):2206. doi:

   Insert

   Keap1 (Kelch-like ECH-associated protein 1) (KEAP1 Human)
   

   Use

   CRISPR and Lentiviral

   Available Since

   Sept. 22, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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4. pLVX-MPro-eGFP-2

   Plasmid

   #184824

   Purpose

   Expresses Mpro-eGFP in mammalian cells

   Depositor

   Wenshe Liu

   Article

   Cao et al ACS Cent Sci. 2022 Feb 23;8(2):192-204.

   Insert

   Mpro-eGFP conjugate (M SARS-CoV-2, jellyfish Aequorea Victoria)
   

   Use

   Lentiviral

   Expression

   Mammalian

   Promoter

   EF-1alfa

   Available Since

   May 17, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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5. pcDNA3-GFP-IMP2-2

   Plasmid

   #42175

   Depositor

   Alexandra Kiemer

   Article

   Kessler et al Am J Physiol Gastrointest Liver Physiol.

   Insert

   Insulin-like growth factor 2 mRNA binding protein 2-2 (IGF2BP2 Human)
   

   Tags

   GFP

   Expression

   Mammalian

   Promoter

   T7

   Available Since

   June 14, 2013

   Availability

   Academic Institutions and Nonprofits only

6. Lenti-sgStk11#2/Cre

   Plasmid

   #173653

   Purpose

   Expresses a Stk11-targeting gRNA and Cre-recombinase

   Depositor

   Charles Swanton

   Article

   Cai et al Cancer Discov. 2021 Feb 19. pii: 2159-82

   Insert

   gRNA targeting Stk11 (Stk11 Mouse)
   

   Use

   CRISPR, Cre/Lox, and Lentiviral

   Available Since

   May 17, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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7. mCerulean3-Bcl-2-s2193

   Plasmid

   #166750

   Purpose

   Express mCerulean3 fused to the N-terminus of the Bcl-2 family protein, Bcl-2 in a plasmid with Blasticidin resistance. Used to make stable BMK-DKO cell lines.

   Depositor

   David Andrews

   Article

   Liu et al Elife. 2019 Mar 12;8. pii: 37689. doi: 1

   Insert

   Bcl-2 (BCL2 Human)
   

   Tags

   mCerulean3

   Expression

   Mammalian

   Promoter

   Human ferritin

   Available Since

   Oct. 4, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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8. pCRISPR Human CASP9 -2

   Plasmid

   #198420

   Purpose

   Expresses Human CASP9 Specific gRNA/Cas9 Complex and Reporter Protein

   Depositor

   Hannah Rabinowich

   Article

   Han et al Autophagy. 2021 Jun;17(6):1393-1409. doi

   Insert

   Human CASP9 Specific gRNA (CASP9 Human)
   

   Use

   CRISPR

   Tags

   Cas9/Orange Fluorescent Protein Reporter

   Expression

   Mammalian

   Promoter

   U6; CMV

   Available Since

   April 14, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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9. pXPR_003 sgSMARCA4 guide 2

   Plasmid

   #193605

   Purpose

   SMARCA4 knockout

   Depositor

   William Hahn

   Article

   Hagel et al Cancer Res. 2022 Dec 22:CAN-22-2245. doi

   Insert

   sgSMARCA4 guide 2 (SMARCA4 Human)
   

   Use

   Lentiviral

   Available Since

   Jan. 3, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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10. lentiCRISPR v2-sgBAX-2

    Plasmid

    #210130

    Purpose

    knock out BAX in mammalian cells

    Depositor

    Boyi Gan

    Article

    Liu et al Nat Cell Biol. 2023 Mar;25(3):404-414. d

    Insert

    Apoptosis regulator BAX (BAX Human)
    

    Use

    CRISPR

    Available Since

    Nov. 8, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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11. pcDNA3.1(+)_Granulin 2+linker3

    Plasmid

    #176920

    Purpose

    express Granulin 2 with linker 3 in mammalian cells

    Depositor

    Thomas Kukar

    Article

    Holler et al eNeuro. 2017 Aug 18;4(4). pii: eN-NWR-01

    Insert

    Granulin 2+linker3 (GRN Human)
    

    Tags

    Twin-Strep and FLAG tags encoded after Signal Pep…

    Expression

    Mammalian

    Available Since

    May 24, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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12. Lenti-sgTsc1#2/Cre

    Plasmid

    #173658

    Purpose

    Expresses a Tsc1-targeting gRNA and Cre-recombinase

    Depositor

    Charles Swanton

    Article

    Cai et al Cancer Discov. 2021 Feb 19. pii: 2159-82

    Insert

    gRNA targeting Tsc1 (Tsc1 Mouse)
    

    Use

    CRISPR, Cre/Lox, and Lentiviral

    Available Since

    Oct. 18, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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13. Lenti-sgPtprd#2/Cre

    Plasmid

    #173648

    Purpose

    Expresses a Ptprd-targeting gRNA and Cre-recombinase

    Depositor

    Charles Swanton

    Article

    Cai et al Cancer Discov. 2021 Feb 19. pii: 2159-82

    Insert

    gRNA targeting Ptprd (Ptprd Mouse)
    

    Use

    CRISPR, Cre/Lox, and Lentiviral

    Available Since

    June 7, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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14. pcDNA3.1(+)_Granulin 2-no linker

    Plasmid

    #176921

    Purpose

    express Granulin 2 without linker 3 in mammalian cells

    Depositor

    Thomas Kukar

    Article

    Holler et al eNeuro. 2017 Aug 18;4(4). pii: eN-NWR-01

    Insert

    Granulin 2 (GRN Human)
    

    Tags

    Twin-Strep and FLAG tags encoded after Signal Pep…

    Expression

    Mammalian

    Available Since

    May 24, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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15. pSpCas9_BB_2A-GFP_MAPRE3-gRNA#2

    Plasmid

    #107730

    Purpose

    Knock out of EB3 in human cells by CRISPR/Cas9

    Depositor

    Torsten Wittmann

    Article

    van Haren et al Nat Cell Biol. 2018 Jan 29. pii: 10.1038

    Insert

    MAPRE3 gRNA #2 (targets Exon 1) (MAPRE3 Human)
    

    Expression

    Mammalian

    Promoter

    U6

    Available Since

    May 1, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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16. Lenti-sgNcor1#2/Cre

    Plasmid

    #173606

    Purpose

    Expresses a Ncor1-targeting gRNA and Cre-recombinase

    Depositor

    Charles Swanton

    Article

    Cai et al Cancer Discov. 2021 Feb 19. pii: 2159-82

    Insert

    gRNA targeting Ncor1 (Ncor1 Mouse)
    

    Use

    CRISPR, Cre/Lox, and Lentiviral

    Available Since

    June 7, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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17. pH-2×35S-DualPE

    Plasmid

    #236416

    Purpose

    For plant prime editing including large DNA fragment editing in Nicotiana benthamiana or other dicotyledons

    Depositor

    Zong Yuan

    Article

    Zhao et al Nat Plants. 2025 Feb;11(2):191-205. doi:

    Inserts

    2×35S promoter
    hygromycin-resistance gene
    

    Use

    CRISPR

    Mutation

    Detailed in manuscript

    Available Since

    Oct. 7, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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18. pLKO-Tet-On shYAP1-2

    Plasmid

    #193665

    Purpose

    Tet inducible knockdown of YAP1

    Depositor

    William Hahn

    Article

    Kim et al Dev Cell. 2022 Jan 24;57(2):212-227.e8.

    Insert

    YAP1 (YAP1 Human)
    

    Use

    Lentiviral

    Available Since

    Dec. 20, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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19. Lenti-sgRbm10#2/Cre

    Plasmid

    #173651

    Purpose

    Expresses a Rbm10-targeting gRNA and Cre-recombinase

    Depositor

    Charles Swanton

    Article

    Cai et al Cancer Discov. 2021 Feb 19. pii: 2159-82

    Insert

    gRNA targeting Rbm10 (Rbm10 Mouse)
    

    Use

    CRISPR, Cre/Lox, and Lentiviral

    Available Since

    June 8, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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20. Lenti-sgRnf43#2/Cre

    Plasmid

    #173614

    Purpose

    Expresses a Rnf43-targeting gRNA and Cre-recombinase

    Depositor

    Charles Swanton

    Article

    Cai et al Cancer Discov. 2021 Feb 19. pii: 2159-82

    Insert

    gRNA targeting Rnf43 (Rnf43 Mouse)
    

    Use

    CRISPR, Cre/Lox, and Lentiviral

    Available Since

    June 7, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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