166,806 results

1. pLVX-DmrB-Casp8-2A-mCherry-puro

   Plasmid

   #231971

   Purpose

   Tet inducible expression of DmrB-Casp8 with mCherry to induce Casp8 apoptosis

   Depositor

   Brian Ruffell

   Article

   Hanggi et al Cancer Cell. 2024 Nov 13:S1535-6108(24)0

   Insert

   Casp8 dimerizing construct with bi-cistronic mCherry (CASP8 Human)
   

   Use

   Lentiviral

   Available Since

   Feb. 5, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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2. pCR-U6-gRNA-TRE3G-TdTomato

   Plasmid

   #192658

   Purpose

   A plasmid encoding TRE3G sgRNA and TRE3G-promoter-TdTomato

   Depositor

   Jeffrey Miner

   Article

   Omachi et al PLoS One. 2022 Jun 28;17(6):e0270008. do

   Insert

   TdTomato
   

   Expression

   Mammalian

   Promoter

   U6, TRE3G

   Available Since

   Jan. 5, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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3. pMZ379

   Plasmid

   #74215

   Purpose

   Combined sgRNA/Cas9 vector with NatMX marker

   Depositor

   Mikel Zaratiegui

   Inserts

   Cas9
   rrk1:sgRNA
   

   Use

   CRISPR

   Expression

   Yeast

   Mutation

   Silent muation of the CspCI site

   Promoter

   adh1 and rrk1

   Available Since

   March 31, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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4. pCMV-ABE6.3

   Plasmid

   #102916

   Purpose

   expresses ABE6.3 in mammalian cells

   Depositor

   David Liu

   Article

   Gaudelli et al Nature. 2017 Nov 23;551(7681):464-471. d

   Insert

   ABE6.3
   

   Tags

   NLS

   Expression

   Mammalian

   Mutation

   see manuscript

   Promoter

   CMV

   Available Since

   Nov. 27, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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5. pFastBac1-Ls-AChBP

   Plasmid

   #63126

   Purpose

   Expression of Lymnaea stagnalis AChBP

   Depositor

   Titia Sixma

   Article

   Celie et al Nat Struct Mol Biol. 2005 Jul;12(7):582-

   Insert

   AChBP
   

   Expression

   Insect

   Promoter

   Polyhedrin

   Available Since

   March 16, 2015

   Availability

   Academic Institutions and Nonprofits only

   

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6. p5E_unc503

   Plasmid

   #64020

   Purpose

   5' Gateway entry vector with muscle-specific promoter of zebrafish unc-45b

   Depositor

   Joachim Berger, Peter Currie

   Article

   Berger et al Genesis. 2013 Jun;51(6):443-7. doi: 10.1

   Insert

   muscle-specific promoter of zebrafish unc-45b (unc45b Zebrafish)
   

   Use

   Gateway

   Promoter

   503-bp promoter of zebrafish unc-45b

   Available Since

   May 15, 2015

   Availability

   Academic Institutions and Nonprofits only

   

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7. pLKO.1_puro_shNRF2-1

   Plasmid

   #230086

   Purpose

   shRNA silencing human NRF2 gene

   Depositor

   Xingguo Zhu

   Article

   Xi et al Commun Biol. 2025 Jan 6;8(1):15. doi: 10

   Insert

   Nrf2 (Nuclear factor-erythroid factor 2-related factor 2) (NFE2L2 Human)
   

   Use

   Lentiviral and RNAi

   Expression

   Mammalian

   Available Since

   Jan. 10, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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8. pAAV-S5E2-GFP-fGFP

   Plasmid

   #135631

   Purpose

   AAV vector to drive the expression of fGFP in PV cortical interneuronsunder the control of the E2 regulatory element

   Depositor

   Jordane Dimidschstein

   Article

   Vormstein-Schneider et al Nat Neurosci. 2020 Dec;23(12):1629-1636.

   Has Service

   AAV PHP.eB, AAV1, and AAV9

   Insert

   GFP-fGFP
   

   Use

   AAV

   Mutation

   None

   Available Since

   Aug. 17, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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9. pQE-WT-RGVG-M6

   Plasmid

   #70172

   Purpose

   Expresses RGVG-M6 T7 RNA polymerase variant with enhanced transcription of 2' modified RNA

   Depositor

   Andrew Ellington

   Article

   Meyer et al Nucleic Acids Res. 2015 Sep 3;43(15):748

   Insert

   RGVG-M6 T7 RNA polymerase
   

   Tags

   His

   Expression

   Bacterial

   Promoter

   T5/Lac

   Available Since

   Dec. 16, 2015

   Availability

   Industry, Academic Institutions, and Nonprofits

   

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10. dSpCas9-VPR

    Plasmid

    #205247

    Purpose

    In vitro transcription plasmid for production of dSpCas9-VPR mRNA for transcriptional activation (VPR = tripartite transactivator VP64, p65, and Rta). Insert is derived from Addgene plasmid #63798.

    Depositor

    Rasmus Bak

    Article

    Jensen et al Genome Res. 2021 Nov;31(11):2120-2130. d

    Insert

    dSpCas9-VPR
    

    Use

    CRISPR

    Available Since

    Sept. 20, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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11. pcDNA-hISG15

    Plasmid

    #12447

    Depositor

    Dong-Er Zhang

    Article

    Kim et al Mol Cell Biol. 2004 Nov . 24(21):9592-60

    Insert

    ISG15 fragment (ISG15 Human)
    

    Expression

    Mammalian

    Mutation

    ISG15 up to LRLRGG

    Available Since

    Jan. 4, 2007

    Availability

    Academic Institutions and Nonprofits only

    

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12. pMRXIP Turquoise2-Syntaxin17

    Plasmid

    #89938

    Purpose

    Expresses Syntaxin17 tagged with Turquoise2 in mammalian cells

    Depositor

    Noboru Mizushima

    Article

    Tsuboyama et al Science. 2016 Nov 25;354(6315):1036-1041

    Insert

    human Syntaxin 17 (STX17 Human)
    

    Use

    Retroviral

    Tags

    mTurquoise2

    Available Since

    June 13, 2017

    Availability

    Academic Institutions and Nonprofits only

    

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13. mARGAna (cassette 1, transient)

    Plasmid

    #197588

    Purpose

    Second-generation mammalian acoustic reporter gene derived from Anabaena

    Depositor

    Mikhail Shapiro

    Article

    Hurt et al Nat Biotechnol. 2023 Jan 2. doi: 10.1038

    Insert

    mARGAna (cassette 1)
    

    Expression

    Mammalian

    Available Since

    March 16, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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14. mARGAna (cassette 2, transient)

    Plasmid

    #197589

    Purpose

    Second-generation mammalian acoustic reporter gene derived from Anabaena

    Depositor

    Mikhail Shapiro

    Article

    Hurt et al Nat Biotechnol. 2023 Jan 2. doi: 10.1038

    Insert

    mARGAna (cassette 2)
    

    Expression

    Mammalian

    Available Since

    March 16, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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15. MSCV-Cas9-2A-BFP

    Plasmid

    #164662

    Purpose

    Retroviral introduction of Cas9 into mammalian cell line coupled to expression of blue fluorescent protein

    Depositor

    Daniel Hodson

    Article

    Caeser et al Nat Commun. 2019 Oct 4;10(1):4543. doi:

    Inserts

    Cas9
    BFP
    

    Use

    CRISPR and Retroviral

    Expression

    Mammalian

    Promoter

    MSSV_LTR

    Available Since

    March 17, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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16. pCMV-FLAG-CAMK2D

    Plasmid

    #221687

    Purpose

    Mammalian expression of FLAG-tagged human CAMK2D

    Depositor

    Derrick Sek Tong Ong

    Article

    Chuah et al Cell Death Differ. 2023 Aug;30(8):1973-1

    Insert

    CAMK2D (CAMK2D Human)
    

    Expression

    Mammalian

    Available Since

    July 29, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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17. pMK1254

    Plasmid

    #133057

    Purpose

    Lentiviral vector with EF1A promoter constitutively expressing a single insert containing the Tau.K18(P301L/V337M)-mRuby2 fusion protein.

    Depositor

    Martin Kampmann

    Article

    Chen et al J Biol Chem. 2019 Oct 2. pii: RA119.0094

    Insert

    Tau.K18(LM)
    

    Use

    Lentiviral

    Tags

    mRuby2

    Expression

    Mammalian

    Promoter

    EF1A

    Available Since

    Jan. 9, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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18. pD649-HAsp-KIR3DL1-Fc(DAPA)-AviTag-6xHis

    Plasmid

    #156757

    Purpose

    Mammalian expression of cell-surface protein extracellular domain fused to Fc(DAPA)-Avi-6xHis. Protein is secreted from cells.

    Depositor

    Chris Garcia

    Article

    Wojtowicz et al Cell. 2020 Aug 20;182(4):1027-1043.e17.

    Insert

    KIR3DL1 (KIR3DL1 Human)
    

    Tags

    Fc(DAPA)-AviTag-6xHis

    Expression

    Mammalian

    Mutation

    Fc region of human IgG contains D265A and P329A m…

    Promoter

    CMV/SP6

    Available Since

    March 8, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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19. pTRETightBI-RY-0

    Plasmid

    #31463

    Depositor

    Phil Sharp

    Article

    Mukherji et al Nat Genet. 2011 Aug 21;43(9):854-9. doi:

    Insert

    eYFP and mCherry
    

    Tags

    NLS

    Expression

    Mammalian

    Available Since

    Jan. 5, 2012

    Availability

    Academic Institutions and Nonprofits only

    

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20. tol2-mpx-mCherry

    Plasmid

    #29585

    Depositor

    Anna Huttenlocher

    Article

    Yoo et al Dev Cell. 2010 Feb 16. 18(2):226-36.

    Insert

    mpx-mCherry
    

    Use

    Zebrafish expression

    Available Since

    June 3, 2011

    Availability

    Academic Institutions and Nonprofits only