165,214 results

1. pHIV-IL13-IgG4hinge-PDGFR

   Plasmid

   #240245

   Purpose

   Lentiviral transfer plasmid encoding IL13 with IgG4 hinge and PDGFR TM domain

   Depositor

   Michael Birnbaum

   Article

   Dobson et al Nat Methods. 2022 Apr;19(4):449-460. doi

   Insert

   IL-13 (IL13 Human)
   

   Use

   Lentiviral

   Tags

   EGFP and HA

   Expression

   Mammalian

   Promoter

   EF1a

   Available Since

   June 18, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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2. 8061-E06

   Plasmid

   #234243

   Purpose

   Gateway ORF Entry clone of human TGFBR3 with stop codon (for native or N-terminal fusions)

   Depositor

   Dominic Esposito

   Insert

   TGFBR3 (TGFBR3 Human)
   

   Use

   Gateway entry clone

   Available Since

   May 29, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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3. pAAV-hSyn-DIO-hM3D(Gq)-mCherry-shLacZ-CWB

   Plasmid

   #223660

   Purpose

   Expresses hM3D(Gq) and a control shRNA (targetting LacZ) in a Cre-dependent manner

   Depositor

   Oscar Marin

   Article

   Selten et al Nature. 2025 Apr 30. doi: 10.1038/s41586

   Insert

   hM3D(Gq)-mCherry and shLacZ
   

   Use

   AAV and RNAi

   Tags

   mCherry

   Expression

   Mammalian

   Promoter

   hSyn

   Available Since

   April 30, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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4. pAAV-hSyn-DIO-Vgf-T2A-mCherry-CW3SL

   Plasmid

   #223661

   Purpose

   Expresses VGF and mCherry in a Cre-dependent manner

   Depositor

   Oscar Marin

   Article

   Selten et al Nature. 2025 Apr 30. doi: 10.1038/s41586

   Insert

   Vgf-T2A-mCherry
   

   Use

   AAV

   Expression

   Mammalian

   Promoter

   hSyn

   Available Since

   April 30, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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5. pAAV-hSyn-DIO-mCherry-CW3SL

   Plasmid

   #223662

   Purpose

   Expresses mCherry in a Cre-dependent manner

   Depositor

   Oscar Marin

   Article

   Selten et al Nature. 2025 Apr 30. doi: 10.1038/s41586

   Insert

   mCherry
   

   Use

   AAV

   Expression

   Mammalian

   Promoter

   hSyn

   Available Since

   April 30, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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6. pAAV-hSyn-DIO-hM3D(Gq)-mCherry-shVgf-CWB

   Plasmid

   #223658

   Purpose

   Expresses hM3D(Gq) and a shRNA targetting VGF in a Cre-dependent manner

   Depositor

   Oscar Marin

   Article

   Selten et al Nature. 2025 Apr 30. doi: 10.1038/s41586

   Insert

   hM3D(Gq)-mCherry and shVGF
   

   Use

   AAV and RNAi

   Tags

   mCherry

   Expression

   Mammalian

   Promoter

   hSyn

   Available Since

   April 30, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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7. pAV-CMVp-2xTetO-Tornado-1xALFATag-5xSunTag

   Plasmid

   #231601

   Purpose

   Express circular RNA translation reporter with 1xALFATag-5xSunTag under CMV promoter

   Depositor

   Marvin Tanenbaum

   Article

   Madern et al Cell. 2025 Jan 23:S0092-8674(25)00045-5.

   Insert

   Tornado-1xALFATag-5xSunTag
   

   Expression

   Mammalian

   Available Since

   April 15, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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8. pAIP4_2PPN

   Plasmid

   #234190

   Purpose

   Heterologous protein expression of peptidyl-prolyl cis-trans isomerase FKBP1A (PPIase FKBP1A) in Escherichia coli

   Depositor

   Christopher Bahl

   Insert

   2PPN (FKBP1A Human)
   

   Tags

   10x HisTag-Smt3

   Expression

   Bacterial

   Promoter

   T7

   Available Since

   March 6, 2025

   Availability

   Industry, Academic Institutions, and Nonprofits

   

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9. p2T-CMV-EA-evoAPOBEC1max-32NLS_NG-BlastR

   Plasmid

   #232722

   Purpose

   C-to-T base editor

   Depositor

   David Liu

   Article

   Matuszek et al Nat Genet. 2025 May 26. doi: 10.1038/s41

   Insert

   evoAPOBEC1max H47E+S48A-32NLS linker-nCas9(NG)-UGI-UGI
   

   Expression

   Mammalian

   Mutation

   within evoAPOBEC1: H47E+S48A; within Cas9 D10A

   Available Since

   March 3, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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10. p2T-U6-sgCTG

    Plasmid

    #232723

    Purpose

    SpCas9 guide RNA targeting CAG repeats for C-to-T base editing

    Depositor

    David Liu

    Article

    Matuszek et al Nat Genet. 2025 May 26. doi: 10.1038/s41

    Insert

    SpCas9 gRNA targeting CAG repeats
    

    Expression

    Mammalian

    Available Since

    March 3, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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11. pABE-dGFP

    Plasmid

    #226863

    Purpose

    Constitutively expresses mCherry as a transfection marker. Expresses non-fluorescent EGFP, deactivated by A111V mutation, that can be reactivated by active adenine base editing

    Depositor

    Alexis Komor

    Article

    Osgood et al Methods in Enzymology, February 5, 2025

    Insert

    EGFP
    

    Expression

    Mammalian

    Mutation

    A111V

    Promoter

    CMV

    Available Since

    Feb. 10, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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12. pABE-dGFP-gRNA

    Plasmid

    #226864

    Purpose

    Human gRNA expression vector targeting the A111V mutation of non-fluorescent EGFP in plasmid pABE-dGFP; for use with ABEs

    Depositor

    Alexis Komor

    Article

    Osgood et al Methods in Enzymology, February 5, 2025

    Insert

    Sp-gRNA
    

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    Feb. 10, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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13. pLV-shFMR1-mCherry

    Plasmid

    #222963

    Purpose

    Make lentivirus to knock down human FMR1 gene

    Depositor

    Xinyu Zhao

    Article

    Guo et al Nat Commun. 2023 Jun 26;14(1):3801. doi:

    Insert

    FMR1 shRNA (FMR1 Human)
    

    Use

    Lentiviral

    Available Since

    Oct. 17, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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14. pSLQ7535 pHR (hU6-crSURF2-EFS-PuroR-WPRE)

    Plasmid

    #214879

    Purpose

    Lentiviral vector encoding RfxCas13d targeting SURF2 guide array

    Depositor

    Stanley Qi

    Article

    Tieu et al Cell. 2024 Feb 29;187(5):1278-1295.e20.

    Insert

    hU6-crSURF2-EFS-PuroR-WPRE
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    April 4, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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15. pBiT3.1-N_DCAF1:1-1507

    Plasmid

    #211028

    Purpose

    Mammalian expression of full-length human DCAF1. N-terminal HiBiT tag.

    Depositor

    Cheryl Arrowsmith

    Article

    Ackloo et al J Med Chem. 2025 Jan 23;68(2):1092-1112.

    Insert

    DCAF1:M1-E1507 (DCAF1 Human)
    

    Tags

    MVSGWRLFKKISGSSGGSSG

    Expression

    Mammalian

    Mutation

    wild type

    Promoter

    CMV

    Available Since

    Feb. 21, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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16. pAAV-hSyn-GFP-IRES-hSNCA (A30P)

    Plasmid

    #185720

    Purpose

    AAV expression of GFP and human α-Synuclein with A30P mutation from hSyn promoter

    Depositor

    Jun Ding

    Article

    Albarran et al Nat Neurosci. 2023 Jun;26(6):997-1007. d

    Insert

    synuclein, alpha (SNCA Human)
    

    Use

    AAV

    Mutation

    Changed Ala 30 to Pro

    Promoter

    hSyn

    Available Since

    April 21, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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17. pD649-HAsp-SEMA5A-COMP5AP-AviTag-9xHis

    Plasmid

    #157572

    Purpose

    Mammalian expression of cell-surface protein extracellular domain fused to COMP5AP-AviTag-9xHis. Protein is secreted from cells.

    Depositor

    Chris Garcia

    Article

    Wojtowicz et al Cell. 2020 Aug 20;182(4):1027-1043.e17.

    Insert

    SEMA5A (SEMA5A Human)
    

    Tags

    COMP5AP-AviTag-9xHis

    Expression

    Mammalian

    Promoter

    CMV/SP6

    Available Since

    March 8, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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18. pQE30-roGFP1-iR

    Plasmid

    #83314

    Purpose

    Inducible expression of redox sensitive GFP in bacteria

    Depositor

    S. James Remington

    Article

    Lohman et al Biochemistry. 2008 Aug 19;47(33):8678-88

    Insert

    roGFP1-iR
    

    Tags

    6xHIS

    Expression

    Bacterial

    Mutation

    ro1(C48S/S147C/Q204C) plus X insertion, iR betwe…

    Promoter

    T5

    Available Since

    Oct. 11, 2016

    Availability

    Academic Institutions and Nonprofits only

19. pGGDestTol2LC-5sgRNA

    Plasmid

    #64243

    Purpose

    destination vector for five U6x:sgRNA cassettes

    Depositor

    Wenbiao Chen

    Article

    Yin et al Genetics. 2015 Apr 8. pii: genetics.115.

    Type

    Empty backbone

    Use

    CRISPR

    Available Since

    May 5, 2015

    Availability

    Academic Institutions and Nonprofits only

    

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20. pSSRB070_pAC8-hsCRBN

    Plasmid

    #218789

    Purpose

    Insect cell expression vector for FLAG-TEV-Spy-hsCRBN

    Depositor

    Eric Fischer

    Article

    Mercer et al Science. 2024 Mar 15;383(6688):eadk4422.

    Insert

    Protein cereblon (CRBN Human)
    

    Tags

    Flag-TEV-Spy

    Expression

    Insect

    Promoter

    polyhedrin

    Available Since

    May 6, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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