We narrowed to 23,698 results for: Spr

1. Lenti_CRISPRi_sgAR3

   Plasmid

   #167002

   Purpose

   Lentiviral expression of sgRNA targeted to the androgen receptor (AR) promoter for CRISPRi knockdown

   Depositor

   Gian-Paolo Dotto

   Article

   Ma et al J Exp Med. 2021 Feb 1;218(2). pii: 21150

   Insert

   AR Promoter sgRNA 3 (AR Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mutation

   Promoter

   U6

   Available since

   April 23, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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2. lentiCRISPR.sgKras.9

   Plasmid

   #91894

   Purpose

   sgRNAs targeting mouse Kras. 3rd generation lentiviral backbone.

   Depositor

   Wen Xue

   Article

   Mou et al Proc Natl Acad Sci U S A. 2017 Apr 4;114

   Insert

   Kras sgRNA
   

   Use

   Lentiviral

   Tags

   Expression

   Mutation

   Promoter

   U6

   Available since

   Dec. 14, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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3. pVD_CRISPR

   Plasmid

   #120370

   Purpose

   Plasmid containing shortened version of V-D CRISPR array for integration assays

   Depositor

   Jennifer Doudna

   Article

   Wright et al Mol Cell. 2019 Feb 21;73(4):727-737.e3.

   Insert

   VD_CRISPR
   

   Use

   CRISPR

   Tags

   Expression

   Mutation

   Promoter

   Available since

   April 12, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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4. pCRISPR_RAF1_94

   Plasmid

   #111826

   Purpose

   Knockout Raf1

   Depositor

   Steve Shih

   Article

   Sinha et al Lab Chip. 2018 Jul 24;18(15):2300-2312.

   Insert

   gRNA targeting RAF1 94-114 (RAF1 Human)
   

   Use

   CRISPR

   Tags

   mCherry

   Expression

   Bacterial and Mammalian

   Mutation

   Promoter

   U6

   Available since

   Aug. 2, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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5. J-SPRTNC-1

   Plasmid

   #166521

   Purpose

   scFv of a human scaffold targeting SprT-like N-terminal domain. Antigen coverage aa 1-216 of 489

   Depositor

   Susanne Gräslund

   Insert

   single chain-Fv, scFv
   

   Use

   Recombinant antibody expression

   Tags

   3xFLAG, His6 and OmpA leader sequence

   Expression

   Bacterial

   Mutation

   Promoter

   LacZ

   Available since

   March 31, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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6. pCRISPR2_+1D

   Plasmid

   #149389

   Purpose

   P. aeruginosa PA14 CRISPR2 locus, with 1bp addition downstream of IHFprox site

   Depositor

   Blake Wiedenheft

   Article

   Santiago-Frangos et al Curr Biol. 2021 Aug 23;31(16):3515-3524.

   Insert

   Pseudomonas aeruginosa PA14 CRISPR2 locus
   

   Use

   Tags

   Expression

   Bacterial

   Mutation

   1bp inserted downstream of the IHFprox site

   Promoter

   pBAD

   Available since

   Aug. 23, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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7. CRISPRmTmG2

   Plasmid

   #69992

   Purpose

   The CRISPR construct targets near the LoxP sites in Rosa-pCA-loxP-mTdtomato-loxP-mEGFP mice.

   Depositor

   Connie Cepko

   Article

   Wang et al Dev Cell. 2014 Sep 8;30(5):513-27. doi:

   Insert

   gRNA that targets near LoxP sites
   

   Use

   Tags

   Expression

   Mutation

   Promoter

   Available since

   May 4, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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8. Lenti_CRISPRi_sgNeg2

   Plasmid

   #166999

   Purpose

   Lentiviral expression of negative control sgRNA for CRISPRi knockdown

   Depositor

   Gian-Paolo Dotto

   Article

   Ma et al J Exp Med. 2021 Feb 1;218(2). pii: 21150

   Insert

   Negative control sgRNA 2
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mutation

   Promoter

   U6

   Available since

   April 23, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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9. p15a_Kan_MLS_Rosa26_Short_CRISPRDel_CAG_RNeoStop_WPRE_bgh_pA

   Plasmid

   #97011

   Purpose

   Rosa26 targeting vector for Dre-responsive cassette

   Depositor

   Russell Ray

   Article

   Lusk et al BMC Biol. 2022 Jan 28;20(1):28. doi: 10.

   Type

   Empty backbone

   Use

   CRISPR and Cre/Lox

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Available since

   March 3, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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10. epiCRISPRe

    Plasmid

    #135962

    Purpose

    Expresses SpCas9, and cloning backbone for sgRNA

    Depositor

    Yongming Wang

    Article

    Xie et al Sci Rep. 2017 May 24;7(1):2320. doi: 10.

    Type

    Empty backbone

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    April 30, 2020

    Availability

    Academic Institutions and Nonprofits only

11. pLentiCRISPRv2_cGAS_gRNA_3

    Plasmid

    #235531

    Purpose

    gRNA against human cGAS

    Depositor

    Nicolas Manel

    Article

    Lahaye et al Cell. 2025 May 29:S0092-8674(25)00556-2.

    Insert

    cGAS (CGAS Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    Available since

    July 17, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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12. pLentiCRISPRv2_IFNB1_gRNA_1

    Plasmid

    #235532

    Purpose

    gRNA against human IFNB1

    Depositor

    Nicolas Manel

    Article

    Lahaye et al Cell. 2025 May 29:S0092-8674(25)00556-2.

    Insert

    IFNB1 (IFNB1 Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    Available since

    July 17, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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13. pLentiCRISPRv2_IFNB1_gRNA_3

    Plasmid

    #235533

    Purpose

    gRNA against human IFNB1

    Depositor

    Nicolas Manel

    Article

    Lahaye et al Cell. 2025 May 29:S0092-8674(25)00556-2.

    Insert

    IFNB1 (IFNB1 Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    Available since

    July 17, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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14. pDCX_mEmerald_CRISPR_HDR

    Plasmid

    #239331

    Purpose

    HDR template to insert mEmerald before the stop codon in exon 7 of the human doublecortin (DCX) locus

    Depositor

    Torsten Wittmann

    Article

    Dema et al Curr Biol. 2024 Nov 21:S0960-9822(24)014

    Insert

    mEmerald and DCX homology arms
    

    Use

    CRISPR

    Tags

    Expression

    Mutation

    Promoter

    None

    Available since

    June 3, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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15. PX459_L31_CRISPR_downstream_sgRNA

    Plasmid

    #235610

    Purpose

    Encodes CRISPR gRNA for cleaving downstream of insertion site at C terminus of mouse Rpl31

    Depositor

    Maria Barna

    Article

    Zhang et al Science. 2025 Mar 7;387(6738):eadn2623.

    Insert

    Rpl31 C-terminus downstream sgRNA
    

    Use

    CRISPR

    Tags

    Expression

    Mutation

    Promoter

    Available since

    April 2, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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16. PX459_L31_CRISPR_upstream_sgRNA

    Plasmid

    #235609

    Purpose

    Encodes CRISPR gRNA for cleaving upstream of insertion site at C terminus of mouse Rpl31

    Depositor

    Maria Barna

    Article

    Zhang et al Science. 2025 Mar 7;387(6738):eadn2623.

    Insert

    Rpl31 C-terminus upstream sgRNA
    

    Use

    CRISPR

    Tags

    Expression

    Mutation

    Promoter

    Available since

    April 2, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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17. Shim_AspRS_3212.91_TP_GFP_pK7fWG2_IVD_FP611

    Plasmid

    #228374

    Purpose

    Expresses N-term transit peptide from Sapria himalayana Aspartate aminoacyl-tRNA synthetase evm.model.fragScaff scaffold 3212.91; determination of S. himalayana AspRS target localization

    Depositor

    Daniel Sloan

    Article

    DeTar et al Proc Natl Acad Sci U S A. 2024 Dec 24;12

    Insert

    N-terminal transit peptide from S. himalayana AspRS evm.model.fragScaff scaffold 3212.91
    

    Use

    Tags

    Green Florescent Protien

    Expression

    Plant

    Mutation

    Promoter

    Available since

    Feb. 26, 2025

    Availability

    Industry, Academic Institutions, and Nonprofits

    

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18. pLentiCRISPRv2_sgALDH7A1

    Plasmid

    #218273

    Purpose

    CRISPR KO plasmid for ALDH7A1 in human cell lines

    Depositor

    Seth Parker

    Article

    Johal et al Cell Rep. 2024 Dec 24;43(12):115069. doi

    Insert

    Inserted sgRNA targetting ALDH7A1 (ALDH7A1 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    U6

    Available since

    Dec. 11, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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19. pLentiCRISPRRv2_sgTom

    Plasmid

    #218346

    Purpose

    CRISPR KO plasmid for tdTomato in human cell lines

    Depositor

    Seth Parker

    Article

    Johal et al Cell Rep. 2024 Dec 24;43(12):115069. doi

    Insert

    Inserted sgRNA targetting tdTomato
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    U6

    Available since

    Dec. 11, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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20. pLSPR22

    Plasmid

    #217307

    Purpose

    Promoterless (SwaI Cutsite) amdS:mRuby3 fusion reporter

    Depositor

    James Fraser

    Article

    Phillips-Rose et al J Fungi (Basel). 2024 Aug 12;10(8):567.

    Insert

    Acetamidase
    

    Use

    Tags

    mRuby3

    Expression

    Yeast

    Mutation

    Promoter

    Available since

    Sept. 11, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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