59,428 results

1. DNA-PKcs PQR>ala

   Plasmid

   #83319

   Purpose

   human DNA-PKcs PQR>ala

   Depositor

   Katheryn Meek

   Article

   Cui et al Mol Cell Biol. 2005 Dec;25(24):10842-52.

   Insert

   human DNA-PKcs (PRKDC Human)
   

   Expression

   Mammalian

   Mutation

   5 phosphorylation sites in the PQR cluster substi…

   Available Since

   Aug. 8, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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2. pBabe-puro Ras V12

   Plasmid

   #1768

   Depositor

   Bob Weinberg

   Insert

   ras V12 (HRAS Human)
   

   Use

   Retroviral

   Expression

   Mammalian

   Mutation

   G12V, constitutively active

   Available Since

   June 3, 2005

   Availability

   Academic Institutions and Nonprofits only

   

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3. pAAV-EF1a-DIO-hM3D(Gq)-mCherry

   Plasmid

   #50460

   Purpose

   Double floxed Gq-coupled hM3D DREADD fused with mCherry under the control of EF1a promoter

   Depositor

   Bryan Roth

   Insert

   hM3D(Gq)-mCherry (CHRM3 Human)
   

   Use

   AAV

   Tags

   mCherry

   Mutation

   See supplemental documents for DREADD mutations

   Promoter

   EF1a

   Available Since

   April 16, 2014

   Availability

   Academic Institutions and Nonprofits only

   

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4. pLVUHshp53

   Plasmid

   #11653

   Purpose

   3rd generation lentiviral transfer vector expressing shp53 under an hUbiquitin promoter.

   Depositor

   Patrick Aebischer, Didier Trono

   Article

   Szulc et al Nat Methods. 2006 Feb;3(2):109-16. doi:

   Insert

   GFP, shRNA against TP53 (TP53 Human)
   

   Use

   Cre/Lox, Lentiviral, and RNAi

   Expression

   Mammalian

   Available Since

   Aug. 17, 2006

   Availability

   Academic Institutions and Nonprofits only

   

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5. SpCas9-NG-ABE8e(V106W)

   Plasmid

   #198533

   Purpose

   Expresses human codon-optimized SpCas9-NG-ABE8e(V106W) and blasticidin resistance: EFS promoter-SpCas9-NG-ABE8e(V106W)-NLS-FLAG-P2A-BSD

   Depositor

   Hyongbum Kim

   Article

   Kim et al Nat Biotechnol. 2024 Mar;42(3):484-497.

   Insert

   SpCas9-NG-ABE8e(V106W)
   

   Use

   CRISPR and Lentiviral

   Tags

   BSD, FLAG, and NLS

   Expression

   Mammalian

   Promoter

   EFS

   Available Since

   Nov. 5, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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6. pLL3.7m-Clover-Geminin(1-110)-IRES-mKO2-Cdt(30-120)

   Plasmid

   #83841

   Purpose

   Fluorescent probe for G1/S transition and M/G1 transition

   Depositor

   Michael Lin

   Article

   Bajar et al Nat Methods. 2016 Oct 31. doi: 10.1038/n

   Insert

   Clover-Geminin(1-110)-IRES-mKO2-Cdt(30-120) (GMNN, CDT1 Human, Synthetic)
   

   Use

   Lentiviral

   Expression

   Mammalian

   Promoter

   CMV

   Available Since

   Jan. 27, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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7. DNA-PKcs ABCDE>A

   Plasmid

   #83318

   Purpose

   human DNA-PKcs/ABCDE>ala

   Depositor

   Katheryn Meek

   Article

   Cui et al Mol Cell Biol. 2005 Dec;25(24):10842-52.

   Insert

   human DNA-PKcs (PRKDC Human)
   

   Expression

   Mammalian

   Mutation

   6 phosphorylation sites in the ABCDE cluster subs…

   Available Since

   Aug. 8, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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8. CL20_mEGFP_KMT2A_MLLT10

   Plasmid

   #205843

   Purpose

   Express mEGFP-tagged fusion protein, KMT2A_MLLT10 from patient-derived sequence

   Depositor

   Richard Kriwacki

   Article

   Tripathi et al Nat Commun. 2023 Sep 28;14(1):6008. doi:

   Insert

   KMT2A_MLLT10 (KMT2A, MLLT10 Human)
   

   Tags

   mEGFP

   Expression

   Mammalian

   Available Since

   Nov. 9, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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9. p53-GFP

   Plasmid

   #11770

   Depositor

   Geoff Wahl

   Insert

   p53 (TP53 Human)
   

   Tags

   GFP

   Expression

   Mammalian

   Mutation

   72R variant of p53

   Available Since

   May 30, 2006

   Availability

   Academic Institutions and Nonprofits only

   

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10. TFORF2660

    Plasmid

    #142350

    Purpose

    Lentiviral vector for overexpressing transcription factor ORFs with unique 24-bp barcodes. Barcodes facilitate identification of transcription factors in pooled screens.

    Depositor

    Feng Zhang

    Article

    Joung et al Cell. 2023 Jan 5;186(1):209-229.e26. doi

    Insert

    STAT1 (STAT1 Human)
    

    Use

    Lentiviral

    Expression

    Mammalian

    Promoter

    EF1a

    Available Since

    June 20, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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11. Orai1-GCaMP6f

    Plasmid

    #73564

    Purpose

    Green fluorescent reporter of Orai1-associated calcium influx

    Depositor

    Michael Cahalan

    Article

    Dynes et al Proc Natl Acad Sci U S A. 2016 Jan 12;11

    Insert

    Orai1-GCaMP6f (ORAI1 Human, Synthetic)
    

    Tags

    GCaMP6f

    Expression

    Mammalian

    Promoter

    CMV Immediate Early

    Available Since

    March 11, 2016

    Availability

    Academic Institutions and Nonprofits only

    

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12. pEM705 Gsz

    Plasmid

    #109355

    Purpose

    GsX chimera with Gαz C-terminus

    Depositor

    Robert Lucas

    Article

    Ballister et al BMC Biol. 2018 Jan 16;16(1):10. doi: 10.

    Insert

    Gsz chimera
    

    Tags

    None

    Expression

    Mammalian

    Promoter

    CAG

    Available Since

    May 11, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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13. pLL3.7m-mTurquoise2-SLBP(18-126)-IRES-H1-mMaroon1

    Plasmid

    #83842

    Purpose

    Fluorescent probe for S/G2 cell cycle transition and G2/M transition

    Depositor

    Michael Lin

    Article

    Bajar et al Nat Methods. 2016 Oct 31. doi: 10.1038/n

    Insert

    mTurquoise2-SLBP(18-126)-IRES-H1-mMaroon1 (H1-0, SLBP Human, Synthetic)
    

    Use

    Lentiviral

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    Nov. 3, 2016

    Availability

    Academic Institutions and Nonprofits only

    

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14. pAcGFP-N1_CBP

    Plasmid

    #221903

    Purpose

    Transient expression of GFP-tagged CBP in mammalian cells

    Depositor

    Daniel Bose

    Insert

    CBP (CREBBP Human)
    

    Tags

    GFP

    Expression

    Mammalian

    Mutation

    N/A

    Available Since

    June 28, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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15. pcDNA Set9 wt

    Plasmid

    #24084

    Depositor

    Danny Reinberg

    Article

    Nishioka et al Genes Dev. 2002 Feb 15. 16(4):479-89.

    Insert

    Set9 (SETD7 Human)
    

    Tags

    FLAG

    Expression

    Mammalian

    Available Since

    Oct. 27, 2010

    Availability

    Academic Institutions and Nonprofits only

    

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16. pENTR221-JUN

    Plasmid

    #79512

    Purpose

    MultiSite Gateway entry clones, second fragment (attL5, attL2) Human JUN CDS

    Depositor

    Peter Jon Nelson

    Article

    Jackel et al Sci Rep. 2016 Oct 3;6:34365. doi: 10.103

    Insert

    JUN (JUN Human)
    

    Use

    Multisite gateway entry clone

    Tags

    HA Tag

    Promoter

    no Promoter

    Available Since

    May 12, 2017

    Availability

    Academic Institutions and Nonprofits only

    

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17. pCDNA3-hTLR4-VenusFlag

    Plasmid

    #197640

    Purpose

    Human TOLL protein expression in mammalian cells

    Depositor

    Haian Fu

    Insert

    TLR4 (TLR4 Human)
    

    Tags

    Venus-Flag

    Expression

    Mammalian

    Available Since

    April 28, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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18. CL20_mEGFP_NUP98_HOXD13

    Plasmid

    #205871

    Purpose

    Express mEGFP-tagged fusion protein, NUP98_HOXD13 from patient-derived sequence

    Depositor

    Richard Kriwacki

    Article

    Tripathi et al Nat Commun. 2023 Sep 28;14(1):6008. doi:

    Insert

    NUP98_HOXD13 (NUP98, HOXD13 Human)
    

    Tags

    mEGFP

    Expression

    Mammalian

    Available Since

    Nov. 9, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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19. pEM705 Gst (Ser)

    Plasmid

    #109354

    Purpose

    GsX chimera with Gαt C-terminus (Pertussis toxin insensitive mutant)

    Depositor

    Robert Lucas

    Article

    Ballister et al BMC Biol. 2018 Jan 16;16(1):10. doi: 10.

    Insert

    Gst chimera
    

    Tags

    None

    Expression

    Mammalian

    Mutation

    Changed Cysteine at position 391 to Serine (Pertu…

    Promoter

    CAG

    Available Since

    May 11, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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20. pHR-UCOE-SFFV-dCas9-mCherry-ZIM3-KRAB

    Plasmid

    #154473

    Purpose

    Expresses dCas9 fused to mCherry and the KRAB domain of ZIM3

    Depositor

    Mikko Taipale

    Article

    Alerasool et al Nat Methods. 2020 Nov;17(11):1093-1096.

    Insert

    ZIM3 (ZIM3 Human)
    

    Use

    Lentiviral

    Tags

    HA

    Expression

    Mammalian

    Mutation

    Includes ZIM3 aa 1-100

    Promoter

    SFFV

    Available Since

    Oct. 5, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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