We narrowed to 15,997 results for: GRN

1. IRAK4 gRNA (BRDN0001149331)

   Plasmid

   #75666

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human IRAK4

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   IRAK4 (IRAK4 Human)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   hU6

   Available Since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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2. LIMK1 gRNA (BRDN0001147777)

   Plasmid

   #76049

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human LIMK1

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   LIMK1 (LIMK1 Human)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   hU6

   Available Since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

3. MAPK8 gRNA (BRDN0001144736)

   Plasmid

   #78046

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human MAPK8

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   MAPK8 (MAPK8 Human)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   hU6

   Available Since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

4. PLK1 gRNA (BRDN0001147678)

   Plasmid

   #76460

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human PLK1

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   PLK1 (PLK1 Human)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   hU6

   Available Since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

5. ANLN A2.2 gRNA

   Plasmid

   #90531

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human ANLN

   Depositor

   Iain Cheeseman

   Article

   McKinley et al Dev Cell. 2017 Feb 27;40(4):405-420.e2.

   Insert

   ANLN (Guide Designation A2.2)
   

   Use

   CRISPR and Lentiviral

   Promoter

   U6

   Available Since

   Aug. 2, 2017

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

6. pDT-sgRNA-XMAS-2x

   Plasmid

   #164414

   Purpose

   Dual targeted guide and cloning vector. Targets pEF-XMAS-2xStop. Guides targeting endogenous sites can be cloned into BbsI sites.

   Depositor

   Xiao Wang

   Article

   Brookhouser et al BMC Biol. 2020 Dec 14;18(1):193. doi: 10

   Insert

   sgRNA
   

   Use

   CRISPR and Synthetic Biology

   Expression

   Mammalian

   Promoter

   U6

   Available Since

   Aug. 4, 2021

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

7. GSK3B gRNA (BRDN0001146763)

   Plasmid

   #77283

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human GSK3B

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   GSK3B (GSK3B Human)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   hU6

   Available Since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

8. LATS2 gRNA (BRDN0001145273)

   Plasmid

   #77899

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human LATS2

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   LATS2 (LATS2 Human)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   hU6

   Available Since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

9. px335 Mettl14 sgRNA #1

   Plasmid

   #61515

   Purpose

   encodes sgRNA sequence for targeting mouse Mettl14 locus (Cas9-Nickase strategy)

   Depositor

   Jacob Hanna

   Article

   Geula et al Science. 2015 Feb 27;347(6225):1002-6. d

   Insert

   gcggcagctcctagctcagc
   

   Use

   CRISPR

   Expression

   Mammalian

   Available Since

   Jan. 6, 2015

   Availability

   Academic Institutions and Nonprofits only

10. px330_P53 exon 8 gRNA

    Plasmid

    #68349

    Purpose

    px330 with gRNA towards P53 exon 8. Cas9 is expressed from a CAG promoter.

    Depositor

    Jannik Elverløv-Jakobsen

    Insert

    P53 exon 8 gRNA
    

    Expression

    Mammalian

    Promoter

    U6

    Available Since

    Oct. 5, 2015

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

11. px330_P53 exon 7 gRNA

    Plasmid

    #68351

    Purpose

    px330 with gRNA towards P53 exon 7. Cas9 is expressed from a CAG promoter.

    Depositor

    Jannik Elverløv-Jakobsen

    Insert

    P53 exon 7 gRNA
    

    Expression

    Mammalian

    Promoter

    U6

    Available Since

    Oct. 5, 2015

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

12. CLK1 gRNA (BRDN0001146454)

    Plasmid

    #76232

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human CLK1

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    CLK1 (CLK1 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

13. CLK1 gRNA (BRDN0001147408)

    Plasmid

    #76233

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human CLK1

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    CLK1 (CLK1 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

14. pGL3-U6-sgRNA_SRD5A1-mcherry

    Plasmid

    #159780

    Purpose

    S. pyogenes sgRNA collocated with pegRNA targeting human SRD5A1 gene

    Depositor

    Xiaolong Wang

    Article

    Liu et al Cell Discov. 2020 Apr 28;6:27. doi: 10.1

    Insert

    spacer of sgRNA targeting SRD5A1 gene (SRD5A1 Human)
    

    Expression

    Mammalian

    Available Since

    Oct. 20, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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15. PPP2R2A B5.5 gRNA

    Plasmid

    #90847

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human PPP2R2A

    Depositor

    Iain Cheeseman

    Article

    McKinley et al Dev Cell. 2017 Feb 27;40(4):405-420.e2.

    Insert

    PPP2R2A (Guide Designation B5.5)
    

    Use

    CRISPR and Lentiviral

    Promoter

    U6

    Available Since

    July 25, 2017

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

16. Zebrafish-gRNA-0008

    Plasmid

    #42248

    Purpose

    gRNA targeted to zebrafish gene tia1l

    Depositor

    Keith Joung

    Article

    Hwang et al Nat Biotechnol. 2013 Jan 29. doi: 10.103

    Insert

    gRNA-tia1l (tia1l Zebrafish)
    

    Use

    CRISPR; Zebrafish expression

    Promoter

    T7

    Available Since

    Jan. 31, 2013

    Availability

    Academic Institutions and Nonprofits only

17. pAC-U63-QtgRNA2.1-8R

    Plasmid

    #170514

    Purpose

    gRNA cloning vector containing a Gal80 Co-CRISPR reporter for tissue-specific CRISPR in somatic tissues.

    Depositor

    Chun Han

    Article

    Koreman et al Proc Natl Acad Sci U S A. 2021 Apr 6;118

    Type

    Empty backbone

    Use

    CRISPR

    Expression

    Insect

    Promoter

    U6:3

    Available Since

    June 10, 2021

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. SIK3 gRNA (BRDN0001144776)

    Plasmid

    #75754

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human SIK3

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    SIK3 (SIK3 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. SIK3 gRNA (BRDN0001148297)

    Plasmid

    #75755

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human SIK3

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    SIK3 (SIK3 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. SIK3 gRNA (BRDN0001148836)

    Plasmid

    #75756

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human SIK3

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    SIK3 (SIK3 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge