Showing: 21 - 40 of 116 results
-
Plasmid#35521PurposeMammalian expression of human DNMT3A with myc tagDepositorInsertDNMT3A (DNMT3A Human)
UseTagsMycExpressionMammalianMutationPromoterCMVAvailabilityAcademic Institutions and Nonprofits only -
pcDNA3/Myc-DNMT3A2
Plasmid#36941DepositorInsertDNMT3A2 (DNMT3A Human)
UseTagsMycExpressionMammalianMutationPromoterAvailabilityAcademic Institutions and Nonprofits only -
p-dCas9-DNMT3a-Hygro
Plasmid#104403Purposetransient expression of dCas9-DNMT3a fusion proteinDepositorInsertDNMT3a (DNMT3A Human)
UseCRISPRTagsExpressionMammalianMutationPromoterCMV promoterAvailabilityAcademic Institutions and Nonprofits only -
scFv-sfGFP-DNMT3A1
Plasmid#102278PurposeThe plasmid encodes a single-chain antibody that binds to the GCN4 peptide from the SunTag system, and is fused to a DNA methyltransferase DNMT3A1DepositorInsertDNMT3A1 (DNMT3A Human)
UseLentiviralTagsscFV-sfGFPExpressionMammalianMutationPromoterAvailabilityAcademic Institutions and Nonprofits only -
DNMT3ACD-CRY2-EGFP
Plasmid#82556PurposeEncodes DMNT3 under LITE2.0 systemDepositorUseAAVTags2A, NLS(alpha-imp), and NLS-VP64ExpressionMammalianMutationCRY2PHR (N-terminal photolyase homology region do…PromoterEF-1alphaAvailabilityAcademic Institutions and Nonprofits only -
Fuw-dCas9-Dnmt3a
Plasmid#84476PurposeLentiviral construct to express dCas9 fused with Dnmt3aDepositorInsertdCas9-Dnmt3a (DNMT3A Human, Synthetic)
UseLentiviralTagsExpressionMammalianMutationPromoterAvailabilityAcademic Institutions and Nonprofits only -
Fuw-dCas9-Dnmt3a_IM
Plasmid#84478PurposeLentiviral construct to express dCas9 fused with an inactive Dnmt3a catalytic domain (E664A, E756A)DepositorInsertdCas9-Dnmt3a_IM
UseLentiviralTagsExpressionMammalianMutationPromoterAvailabilityAcademic Institutions and Nonprofits only -
138-dCas9-Dnmt3a
Plasmid#84570PurposePiggyBac transposon system construct with dCas9-Dnmt3aDepositorInsertdCas9-Dnmt3a (DNMT3A Human, Synthetic)
UseTagsExpressionMammalianMutationPromoterAvailabilityAcademic Institutions and Nonprofits only -
Lenti-sgDnmt3a#1/Cre
Plasmid#173587PurposeExpresses a Dnmt3a-targeting gRNA and Cre-recombinaseDepositorInsertgRNA targeting Dnmt3a (Dnmt3a Mouse)
UseCRISPR, Cre/Lox, and LentiviralTagsExpressionMutationPromoterAvailabilityAcademic Institutions and Nonprofits only -
Lenti-sgDnmt3a#2/Cre
Plasmid#173588PurposeExpresses a Dnmt3a-targeting gRNA and Cre-recombinaseDepositorInsertgRNA targeting Dnmt3a (Dnmt3a Mouse)
UseCRISPR, Cre/Lox, and LentiviralTagsExpressionMutationPromoterAvailabilityAcademic Institutions and Nonprofits only -
pdCas9-DNMT3A-PuroR_BACH2-sgRNA8
Plasmid#71828PurposeExpression of dCas9-DNMT3A fusion with T2A-PuroR and specific sgRNA for targeted DNA methylation of BACH2 promoter in human cells; for use as a controlDepositorInsertBACH2-sgRNA8 (BACH2 S. pyogenes, Human, Synthetic)
UseCRISPRTags3xFLAG, SV40 NLS, and T2A-PuroRExpressionMammalianMutationD10A and H840A in S.pyogenes Cas9PromoterU6AvailabilityAcademic Institutions and Nonprofits only -
pdCas9-DNMT3A-PuroR (ANV)
Plasmid#71684PurposeExpression of mutant human codon-optimized dCas9-DNMT3A fusion (inactive catalytic domain of DNMT3A) with T2A-PuroR; cloning backbone for sgRNADepositorInsertS. pyogenes dCas9 fused with the inactivated (E756A) catalytic domain of human DNMT3A (amino acids P602-V912) and T2A-PuroR (DNMT3A S. pyogenes, Human, Synthetic)
UseCRISPRTags3xFLAG, SV40 NLS, and T2A-PuroRExpressionMammalianMutationD10A and H840A in S.pyogenes Cas9; E756A inactiva…PromoterCBhAvailabilityAcademic Institutions and Nonprofits only -
pdCas9-DNMT3A-EGFP (ANV)
Plasmid#71685PurposeExpression of mutant human codon-optimized dCas9-DNMT3A fusion (inactive catalytic domain of DNMT3A) with T2A-EGFP; cloning backbone for sgRNADepositorInsertS. pyogenes dCas9 fused with the inactivated (E756A) catalytic domain of human DNMT3A (amino acids P602-V912) and T2A-EGFP (DNMT3A S. pyogenes, Human, Synthetic)
UseCRISPRTags3xFLAG, SV40 NLS, and T2A-EGFPExpressionMammalianMutationD10A and H840A in S.pyogenes Cas9; E756A inactiva…PromoterCBhAvailabilityAcademic Institutions and Nonprofits only -
p-dCas9-dDNMT3a-C706S-Hygro
Plasmid#104412Purposetransient expression of dCas9-dDNMT3a fusion proteinDepositorInsertdDNMT3a
UseCRISPRTagsExpressionMammalianMutationC706SPromoterCMV promoterAvailabilityAcademic Institutions and Nonprofits only -
LLP185 pLVP-dCas9-DNMT3a V2
Plasmid#100936PurposedCas9 and DNMT WT on C terminus, 4 NLS, driven by pGK promoter, with P2A site and PURO gene, within a lentiviral transfer backboneDepositorInsertdCas9, DNMT3a catalytic domain (DNMT3A Human, S.pyogenes)
UseCRISPR and LentiviralTags3xHA and 3xTy1ExpressionMammalianMutationD10A, H840A for dCas9PromoterAvailabilityAcademic Institutions and Nonprofits only -
LLP245 pEF1a-TALE-DNMT3a-Wt
Plasmid#100937PurposeEmpty TALE vector driven by EF1a promoter, no Puro, contains DNMT3a catalytic domainDepositorInsertTALE insertion site, DNMT3a catalytic domain (DNMT3A Human, Synthetic)
UseTALENTags3xHA and 3xTy1ExpressionMammalianMutationPromoterAvailabilityAcademic Institutions and Nonprofits only -
LLP249 pGK-dCas9-DNMT3a V3
Plasmid#100938PurposedCas9 and DNMT WT driven by pGK promoter and Puromycin driven by EF1aDepositorInsertdCas9, DNMT3a catalytic domain (DNMT3A Human, S.pyogenes)
UseCRISPR and LentiviralTags3xHA and 3xTy1ExpressionMammalianMutationD10A, H840A for dCas9PromoterAvailabilityAcademic Institutions and Nonprofits only -
pAPM-D4 miR30-DNMT3a ts1
Plasmid#115865PurposeDNMT3a knockdownDepositorInsertDNMT3a shRNA (DNMT3A Human)
UseLentiviralTagsExpressionMutationPromoterSFFVAvailabilityAcademic Institutions and Nonprofits only -
pAPM-D4 miR30-DNMT3a ts2
Plasmid#115866PurposeDNMT3a knockdownDepositorInsertDNMT3a shRNA (DNMT3A Human)
UseLentiviralTagsExpressionMutationPromoterSFFVAvailabilityAcademic Institutions and Nonprofits only -
pAPM-D4 miR30-DNMT3a ts3
Plasmid#115867PurposeDNMT3a knockdownDepositorInsertDNMT3a shRNA (DNMT3A Human)
UseLentiviralTagsExpressionMutationPromoterSFFVAvailabilityAcademic Institutions and Nonprofits only
Showing: 21 - 40 of 116 results