380 results

1. Mouse Liver CRISPR Knockout Library

   Pooled Library

   #192824

   Purpose

   CRISPR screening library containing ~72,000 sgRNAs

   Depositor

   Kristin Knouse

   Article

   Keys et al Cell Genom. 2022 Dec 14;2(12):100217. do

   Expression

   Mammalian

   Species

   Mus musculus

   Use

   CRISPR and Lentiviral

   Available since

   Dec. 1, 2022

   Availability

   Academic Institutions and Nonprofits only

2. Sabatini/Lander Lab Activity-Optimized Genome-wide Mouse sgRNA Library in pLenti-sgRNA

   Pooled Library

   #1000000096

   Purpose

   CRISPR gRNA knockout pooled library for targeting the mouse genome

   Depositor

   David Sabatini, Eric Lander

   Available since

   April 3, 2017

   Availability

   Academic Institutions and Nonprofits only

3. Human Brunello kinome pooled library, guides 1-4 in lentiGuide-Puro backbone

   Pooled Library

   #75312

   Purpose

   Human sgRNA library in backbone lentiGuide-Puro targeting 763 kinase genes and containing 3,052 unique sgRNAs along with 100 non-targeting controls

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available since

   June 27, 2016

   Availability

   Academic Institutions and Nonprofits only

4. mCRISPRa-v2, Cancer and Apoptosis (m2), top 5 sgRNAs/gene

   Pooled Library

   #83999

   Purpose

   Mouse CRISPRa Pooled Library targeting cancer and apoptosis genes

   Depositor

   Jonathan Weissman

   Article

   Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

   Available since

   Jan. 12, 2017

   Availability

   Academic Institutions and Nonprofits only

5. LV2btCRISPRko.v1

   Pooled Library

   #213927

   Purpose

   Uses lentivirus to deliver the library into hard-to-transduce cells

   Depositor

   Wenfang Spring Tan

   Article

   Tan et al PLoS Pathog. 2023 Dec 6;19(12):e1011822.

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available since

   April 9, 2024

   Availability

   Academic Institutions and Nonprofits only

6. hCRISPRa-v2, Mitochondria, Trafficking, and Motility (h4), top 5 sgRNAs/gene

   Pooled Library

   #83983

   Purpose

   Human CRISPRa Pooled Library targeting Mitochondria, Trafficking, and Motility genes

   Depositor

   Jonathan Weissman

   Article

   Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

   Available since

   Jan. 12, 2017

   Availability

   Academic Institutions and Nonprofits only

7. Wei lab paired-guide RNA (pgRNA) CRISPR–Cas9 library for human long non-coding RNAs (lncRNAs)

   Pooled Library

   #89640

   Purpose

   Paired sgRNA library containing 12,472 pgRNAs targeting 671 human long non-coding RNAs (lncRNAs)

   Depositor

   Wensheng Wei

   Article

   Zhu et al Nat Biotechnol. 2016 Dec;34(12):1279-128

   Expression

   Mammalian

   Use

   Lentiviral

   Available since

   May 17, 2017

   Availability

   Academic Institutions and Nonprofits only

8. Human CRISPR Knockout Pooled Library (H3)

   Pooled Library

   #133914

   Purpose

   CRISPR gRNA knockout pooled library for targeting the human genome - version H3

   Depositor

   Myles Brown, Xiaole Shirley Liu

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   Jan. 24, 2020

   Availability

   Academic Institutions and Nonprofits only

9. Sabatini/Lander Lab Activity-Optimized Genome-wide Human sgRNA Library in pLenti-sgRNA

   Pooled Library

   #1000000095

   Purpose

   CRISPR gRNA knockout pooled library for targeting the human genome

   Depositor

   David Sabatini, Eric Lander

   Available since

   April 3, 2017

   Availability

   Academic Institutions and Nonprofits only

10. Synuclein VHH Immune Library

    Pooled Library

    #1000000071

    Purpose

    Synuclein phagemid VHH phage display library

    Depositor

    Michael J Fox Foundation MJFF, Anne Messer

    Available since

    June 14, 2016

    Availability

    Industry, Academic Institutions, and Nonprofits

11. mCRISPRa-v2, Gene Expression (m5), top 5 sgRNAs/gene

    Pooled Library

    #84002

    Purpose

    Mouse CRISPRa Pooled Library targeting gene expression

    Depositor

    Jonathan Weissman

    Article

    Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

    Available since

    Jan. 12, 2017

    Availability

    Academic Institutions and Nonprofits only

12. TBG-mTSG

    Pooled Library

    #113585

    Purpose

    AAV-CRISPR library for pool mutagenesis of top tumor suppressor genes in mouse liver

    Depositor

    Sidi Chen

    Article

    Wang et al Sci Adv. 2018 Feb 28;4(2):eaao5508. doi:

    Expression

    Mammalian

    Use

    AAV, CRISPR, Lentiviral, and Luciferase

    Available since

    July 23, 2019

    Availability

    Academic Institutions and Nonprofits only

13. hCRISPRa-v2, Stress and Proteostasis (h3), top 5 sgRNAs/gene

    Pooled Library

    #83982

    Purpose

    Human CRISPRa Pooled Library targeting stress and proteostasis genes

    Depositor

    Jonathan Weissman

    Article

    Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

    Available since

    Jan. 12, 2017

    Availability

    Academic Institutions and Nonprofits only

14. Human Lentiviral sgRNA Library - Control

    Pooled Library

    #51048

    Purpose

    Sub-pool of Sabatini/Lander sgRNA library enriched for control targets.

    Depositor

    David Sabatini, Eric Lander

    Article

    Wang et al Science. 2014 Jan 3;343(6166):80-4. doi:

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    Feb. 7, 2014

    Availability

    Academic Institutions and Nonprofits only

15. CRISPRi non-coding library (CRiNCL) - Common to all 7 cell lines

    Pooled Library

    #86538

    Depositor

    Jonathan Weissman

    Article

    Liu et al Science. 2017 Jan 06. Vol. 355, Issue 63

    Available since

    March 8, 2017

    Availability

    Academic Institutions and Nonprofits only

16. hCRISPRi-v2, Cancer and Apoptosis (h2), top 5 sgRNAs/gene

    Pooled Library

    #83972

    Purpose

    Human CRISPRi Pooled Library targeting cancer and apoptosis genes

    Depositor

    Jonathan Weissman

    Article

    Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

    Available since

    Dec. 14, 2016

    Availability

    Academic Institutions and Nonprofits only

17. scQers promoter control #5 (high: EEF1A1 promoter, p028)

    Pooled Library

    #217424

    Purpose

    scQers promoter control #5 (high: EEF1A1 promoter, p028)

    Depositor

    Jay Shendure

    Article

    Lalanne et al bioRxiv 2022.12.10.519236

    Expression

    Bacterial and Mammalian

    Use

    RNAi

    Available since

    April 3, 2024

    Availability

    Academic Institutions and Nonprofits only

18. pRep-Cap Scanning Saturation Mutagenesis (SSM) pooled library

    Pooled Library

    #199601

    Purpose

    pRep-Cap SSM library enables VP1, VP2, and VP3 expression under the control of the endogenous p40 promoter

    Depositor

    George Church

    Article

    Ogden et al Science. 2019 Nov 29;366(6469):1139-1143

    Expression

    Mammalian

    Species

    Aav2

    Use

    AAV

    Available since

    June 13, 2023

    Availability

    Academic Institutions and Nonprofits only

19. Human lentiviral CRISPR library_v1

    Pooled Library

    #69763

    Purpose

    Genome-scale sgRNA screening library in lentiviral vector pLB, targeting 20,121 human protein-coding genes

    Depositor

    Haoquan Wu

    Article

    Ma et al Cell Rep. 2015 Jul 28;12(4):673-83. doi:

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    Feb. 9, 2016

    Availability

    Academic Institutions and Nonprofits only

20. Mouse Base Editing Sensor Library

    Pooled Library

    #179217

    Purpose

    sgRNAs that target frequently occurring cancer associated mutations identified in the MSK IMPACT dataset that can be modeled with cytosine base editing.

    Depositor

    Lukas Dow

    Article

    Sanchez-Rivera et al Nat Biotechnol. 2022 Feb 14. pii: 10.103

    Expression

    Mammalian

    Use

    Lentiviral

    Available since

    June 16, 2022

    Availability

    Academic Institutions and Nonprofits only