We narrowed to 173 results for: ide

1. Human Lipid Droplet and Metabolism Library

   Pooled Library

   #191535

   Purpose

   Targets 1,196 genes related to lipid droplet biology and cell metabolism.

   Depositor

   James Olzmann

   Article

   Roberts et al Dev Cell. 2023 Jul 18:S1534-5807(23)0033

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available Since

   March 1, 2023

   Availability

   Academic Institutions and Nonprofits only

2. mTORC1 Focused library

   Pooled Library

   #164084

   Purpose

   Knockout library targeting human genes required for mTORC1 activation and inhibition.

   Depositor

   David Sabatini

   Article

   Condon et al Proc Natl Acad Sci U S A. 2021 Jan 26;11

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available Since

   Jan. 11, 2021

   Availability

   Academic Institutions and Nonprofits only

3. Splicing-targeting CRISPR-Cas9 library for human lncRNAs

   Pooled Library

   #119977

   Purpose

   Designed for genomic deletion screening of functional lncRNAs by targeting their splice sites.

   Depositor

   Wensheng Wei

   Article

   Liu et al Nat Biotechnol. 2018 Nov 5. pii: nbt.428

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available Since

   March 27, 2019

   Availability

   Academic Institutions and Nonprofits only

4. BARBEKO sgRNA library

   Pooled Library

   #174163

   Purpose

   Cytosine base editors for genome-scale knockout screens in human cells. Targets gene start codons, splice sites, or introduces premature termination codons.

   Depositor

   Wensheng Wei

   Article

   Xu et al Nat Biotechnol. 2021 Jun 21. pii: 10.103

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available Since

   Aug. 31, 2021

   Availability

   Academic Institutions and Nonprofits only

5. Human lentiviral CRISPR library_v1

   Pooled Library

   #69763

   Purpose

   Used for genome scale lentiviral CRISPR screening. Target sites were chosen in a region close to the translation initiation site.

   Depositor

   Haoquan Wu

   Article

   Ma et al Cell Rep. 2015 Jul 28;12(4):673-83. doi:

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available Since

   Feb. 9, 2016

   Availability

   Academic Institutions and Nonprofits only

6. pRep-Cap Scanning Saturation Mutagenesis (SSM) pooled library

   Pooled Library

   #199601

   Purpose

   pRep-Cap SSM library enables VP1, VP2, and VP3 expression under the control of the endogenous p40 promoter

   Depositor

   George Church

   Article

   Ogden et al Science. 2019 Nov 29;366(6469):1139-1143

   Expression

   Mammalian

   Species

   Aav2

   Use

   AAV

   Available Since

   June 13, 2023

   Availability

   Academic Institutions and Nonprofits only

7. CRISPRi non-coding library (CRiNCL) - Common to all 5 cancer cell lines

   Pooled Library

   #86539

   Depositor

   Jonathan Weissman

   Article

   Liu et al Science. 2017 Jan 06. Vol. 355, Issue 63

   Available Since

   March 8, 2017

   Availability

   Academic Institutions and Nonprofits only

8. Human Paralog Knockout Library (pgPEN)

   Pooled Library

   #171172

   Purpose

   Induces knockouts of paralogous gene pairs. Plasmids express a pair of guide RNAs targeting either individual genes or a pair of paralogs.

   Depositor

   Alice Berger

   Article

   Parrish et al Cell Rep. 2021 Aug 31;36(9):109597. doi:

   Expression

   Mammalian

   Species

   Homo sapiens and Synthetic

   Use

   CRISPR and Lentiviral

   Available Since

   Sept. 28, 2021

   Availability

   Academic Institutions and Nonprofits only

9. mTF-CRISPRai

   Pooled Library

   #122131

   Purpose

   Increases transcriptional repression of genes encoding transcription factors in combination with dCas9 repression systems, such as the dCas9-KRAB system.

   Depositor

   Stanley Qi

   Article

   Liu et al Cell Stem Cell. 2018 Sep 28. pii: S1934-

   Expression

   Mammalian

   Species

   Mus musculus

   Use

   CRISPR and Lentiviral

   Available Since

   April 25, 2019

   Availability

   Academic Institutions and Nonprofits only

10. Compact mismatched sgRNA library for gene titration (human essential genes, CRISPRi)

    Pooled Library

    #136479

    Purpose

    Expresses gRNAs for gene titration of ~2400 human genes using CRISPRi

    Depositor

    Jonathan Weissman

    Article

    Jost et al Nat Biotechnol. 2020 Jan 13. pii: 10.103

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available Since

    Feb. 25, 2020

    Availability

    Academic Institutions and Nonprofits only

11. Human SLC SAM Library

    Pooled Library

    #132561

    Purpose

    Activation library targeting human SLC proteins.

    Depositor

    Giulio Superti-Furga

    Article

    Rebsamen et al Life Sci Alliance. 2022 Sep 16;5(11):e20

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available Since

    May 18, 2020

    Availability

    Academic Institutions and Nonprofits only

12. SARS-CoV-2 Spike (S) Ectodomain Library C

    Pooled Library

    #157973

    Purpose

    Encodes Spike ectodomain mutations that stabilize 'up' prefusion conformation

    Depositor

    Timothy Whitehead

    Article

    Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:

    Expression

    Bacterial and Yeast

    Species

    Sars-cov-2

    Available Since

    Sept. 13, 2021

    Availability

    Academic Institutions and Nonprofits only

13. SARS-CoV-2 Spike (S) Ectodomain Library B

    Pooled Library

    #157972

    Purpose

    Encodes Spike ectodomain mutations that stabilize 'up' prefusion conformation

    Depositor

    Timothy Whitehead

    Article

    Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:

    Expression

    Bacterial and Yeast

    Species

    Sars-cov-2

    Available Since

    Sept. 13, 2021

    Availability

    Academic Institutions and Nonprofits only

14. SARS-CoV-2 Spike (S) Ectodomain Library A

    Pooled Library

    #157971

    Purpose

    Encodes Spike ectodomain mutations that stabilize 'up' prefusion conformation

    Depositor

    Timothy Whitehead

    Article

    Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:

    Expression

    Bacterial and Yeast

    Species

    Sars-cov-2

    Available Since

    Sept. 13, 2021

    Availability

    Academic Institutions and Nonprofits only

15. Large-scale mismatched sgRNA library for gene titration (human essential genes, CRISPRi)

    Pooled Library

    #136478

    Purpose

    Expresses gRNAs for gene titration of ~2400 human genes using CRISPRi

    Depositor

    Jonathan Weissman

    Article

    Jost et al Nat Biotechnol. 2020 Jan 13. pii: 10.103

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available Since

    Feb. 25, 2020

    Availability

    Academic Institutions and Nonprofits only

16. BLaER1 pgRNA CRISPR library

    Pooled Library

    #183825

    Purpose

    Paired gRNA library targeting genes related to B-cell to macrophage transdifferentiation.

    Depositor

    Roderic Guigo

    Article

    Arnan et al BMC Genomics. 2022 May 26;23(1):402. doi

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available Since

    Aug. 25, 2022

    Availability

    Academic Institutions and Nonprofits only

17. Human SLC KO Library

    Pooled Library

    #132552

    Purpose

    Knockout library targeting human SLC proteins.

    Depositor

    Giulio Superti-Furga

    Article

    Girardi et al Nat Chem Biol. 2020 Apr;16(4):469-478. d

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available Since

    May 7, 2020

    Availability

    Academic Institutions and Nonprofits only

18. SARS-CoV-2 Spike (S) Receptor Binding Domain (RBD) library 1

    Pooled Library

    #168776

    Purpose

    Pooled library expressing barcoded SARS-CoV-2 RNA Binding Domain mutations

    Depositor

    Timothy Whitehead

    Article

    Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:

    Expression

    Yeast

    Species

    Sars-cov-2

    Available Since

    Sept. 13, 2021

    Availability

    Academic Institutions and Nonprofits only

19. SARS-CoV-2 Spike (S) Receptor Binding Domain (RBD) library 2

    Pooled Library

    #168777

    Purpose

    Pooled library expressing barcoded SARS-CoV-2 RNA Binding Domain mutations

    Depositor

    Timothy Whitehead

    Article

    Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:

    Expression

    Yeast

    Species

    Sars-cov-2

    Available Since

    Sept. 13, 2021

    Availability

    Academic Institutions and Nonprofits only

20. Mouse Chromatin Regulator Library

    Pooled Library

    #200011

    Purpose

    Knockout library targeting a comprehensive set of mouse genes with annotated function as chromatin regulators.

    Depositor

    Bradley Bernstein, Gabriel Griffin, Robert Manguso

    Article

    Griffin et al Nature. 2021 Jul;595(7866):309-314. doi:

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available Since

    Dec. 15, 2023

    Availability

    Academic Institutions and Nonprofits only