390 results

#221409

gRNA library to test the impact of transporters on biological processes

RESOLUTE Consortium, Giulio Superti-Furga

Wolf et al Cell Chem Biol. 2024 Dec 24:S2451-9456(2

Sept. 13, 2024

Academic Institutions and Nonprofits only

#113584

AAV-CRISPR library for pool mutagenesis of top tumor suppressor genes

Sidi Chen

Wang et al Sci Adv. 2018 Feb 28;4(2):eaao5508. doi:

July 23, 2019

Academic Institutions and Nonprofits only

#180272

Tiles the entire ~154 kb of the BAC16 Kaposi’s Sarcoma-associated Herpes Virus genome. A guide every ~8 bp allows pooled screening of the viral genome.

Britt Glaunsinger

Morgens et al PLoS Pathog. 2022 Jan 18;18(1):e1010236.

Feb. 11, 2022

Academic Institutions and Nonprofits only

#190744

Targets proximal poly(A) signal sequences in genes identified to be differentially polyadenylated in the mouse B16-F10 melanoma system.

Robert Bradley

Gabel et al Nat Commun. 2024 Feb 1;15(1):959. doi: 1

Feb. 2, 2024

Academic Institutions and Nonprofits only

#174197

MusCK library contains 23,622 unique sgRNAs targeting 4,787 gene locations in the genome. Sub-library MusCK M_b contains 5 gRNAs per gene.

Xiaole Shirley Liu

Wang et al Cell. 2021 Oct 14;184(21):5357-5374.e22.

Oct. 29, 2021

Academic Institutions and Nonprofits only

#86546

Jonathan Weissman

Liu et al Science. 2017 Jan 06. Vol. 355, Issue 63

March 8, 2017

Academic Institutions and Nonprofits only

#1000000188

Jesse Bloom

June 14, 2022

Academic Institutions and Nonprofits only

#1000000248

Tyler Starr

Sept. 6, 2024

Academic Institutions and Nonprofits only

#86547

Jonathan Weissman

Liu et al Science. 2017 Jan 06. Vol. 355, Issue 63

March 8, 2017

Academic Institutions and Nonprofits only

#83977

Human CRISPRi Pooled Library targeting unassigned genes

Jonathan Weissman

Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

Dec. 14, 2016

Academic Institutions and Nonprofits only

#209736

CHyMErA Exon Deletion hgRNA Library allows identification of frame-preserving exons that affect cell fitness in human cells using the CHyMErA screening platform.

Thomas Gonatopoulos-Pournatzis

Xiao et al Mol Cell. 2024 Jul 11;84(13):2553-2572.e

June 20, 2024

Academic Institutions and Nonprofits only

#86549

Jonathan Weissman

Liu et al Science. 2017 Jan 06. Vol. 355, Issue 63

March 8, 2017

Academic Institutions and Nonprofits only

#86548

Jonathan Weissman

Liu et al Science. 2017 Jan 06. Vol. 355, Issue 63

March 8, 2017

Academic Institutions and Nonprofits only

#86545

Jonathan Weissman

Liu et al Science. 2017 Jan 06. Vol. 355, Issue 63

March 8, 2017

Academic Institutions and Nonprofits only

#173195

Knockout library targeting human E-boxes genome-wide.

Agnieszka Dzikiewicz-Krawczyk

Kazimierska et al Mol Oncol. 2023 Nov;17(11):2295-2313. do

Aug. 11, 2021

Academic Institutions and Nonprofits only

#207478

HA-GD2-28z CAR in combination with 100 transcription factors (and related proteins) and 2 controls (GFP/RFP). Library can be used to generate HDR templates for modular pooled knockin (ModPoKI) into th

Alexander Marson

Blaeschke et al Cell. 2023 Sep 14;186(19):4216-4234.e33.

Jan. 26, 2024

Academic Institutions and Nonprofits only

#207480

HA-GD2-28z CAR in combination with ~10,000 transcription factor combinations (and related proteins) and controls (GFP/RFP combinations). Library can be used to generate HDR templates for modular poole

Alexander Marson

Blaeschke et al Cell. 2023 Sep 14;186(19):4216-4234.e33.

Jan. 26, 2024

Academic Institutions and Nonprofits only

#64750

Library designed for genomic targeting and screening in Drosophila cells. All possible gRNA target sites within the shared exonic regions on either DNA strand of the Drosophila genome were computed.

Ji-Long Liu

Bassett et al J Genet Genomics. 2015 Jun 20;42(6):301-

March 7, 2016

Academic Institutions and Nonprofits only

#75313

Human sgRNA library in backbone lentiGuide-Puro targeting 763 kinase genes and containing 3,052 unique sgRNAs along with 100 non-targeting controls

John Doench, David Root

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

June 27, 2016

Academic Institutions and Nonprofits only

#62843

amplified library of Salpingoeca rosetta

Nicole King

Fairclough et al Genome Biol. 2013 Feb 18;14(2):R15. doi:

June 16, 2015

Academic Institutions and Nonprofits only

#1000000209

Jesse Rinehart

Dec. 14, 2022

Academic Institutions and Nonprofits only

#188527

Express a library of MBP-Fusion proteins containing phosphoserine at a defined position in the fusion protein

Jesse Rinehart

Gassaway et al Nat Methods. 2022 Oct 24. pii: 10.1038/s

Dec. 14, 2022

Academic Institutions and Nonprofits only

#92384

CRISPRa

John Doench, David Root

Sanson et al Nat Commun. 2018 Dec 21;9(1):5416. doi:

July 13, 2018

Academic Institutions and Nonprofits only

#62844

amplified library of Salpingoeca rosetta from a colony rich culture which included the colony inducing bacteria Algoriphagus machipongonensis

Nicole King

Fairclough et al Genome Biol. 2013 Feb 18;14(2):R15. doi:

June 16, 2015

Academic Institutions and Nonprofits only

#187250

Ultra-compact, human genome-wide CRISPRi library targeting each gene with a single element encoding a dual sgRNA cassette.

Marco Jost, Jonathan Weissman

Replogle et al eLife. 2022 Dec 28;11:e81856. doi: 10.75

Sept. 30, 2022

Academic Institutions and Nonprofits only

#187251

Ultra-compact, human genome-wide CRISPRi library targeting each gene with a single element encoding a dual sgRNA cassette.

Marco Jost, Jonathan Weissman

Replogle et al eLife. 2022 Dec 28;11:e81856. doi: 10.75

Sept. 30, 2022

Academic Institutions and Nonprofits only

#1000000185

Jesse Bloom

June 14, 2022

Academic Institutions and Nonprofits only

#1000000214

Georg Seelig

March 31, 2023

Academic Institutions and Nonprofits only

#168776

Pooled library expressing barcoded SARS-CoV-2 RNA Binding Domain mutations

Timothy Whitehead

Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:

Sept. 13, 2021

Academic Institutions and Nonprofits only

#168777

Pooled library expressing barcoded SARS-CoV-2 RNA Binding Domain mutations

Timothy Whitehead

Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:

Sept. 13, 2021

Academic Institutions and Nonprofits only

#157973

Encodes Spike ectodomain mutations that stabilize 'up' prefusion conformation

Timothy Whitehead

Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:

Sept. 13, 2021

Academic Institutions and Nonprofits only

#157972

Encodes Spike ectodomain mutations that stabilize 'up' prefusion conformation

Timothy Whitehead

Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:

Sept. 13, 2021

Academic Institutions and Nonprofits only

#157971

Encodes Spike ectodomain mutations that stabilize 'up' prefusion conformation

Timothy Whitehead

Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:

Sept. 13, 2021

Academic Institutions and Nonprofits only

#174296

This library contains mutations to SARS-CoV-2 Spike RBD N501Y variant in which all surface exposed residues on S RBD (Tile 2, positions 437-527) were mutated to every other amino acid.

Timothy Whitehead

Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:

Sept. 13, 2021

Academic Institutions and Nonprofits only

#174295

This library contains mutations to SARS-CoV-2 Spike RBD N501Y variant in which all surface exposed residues on S RBD (Tile 1, positions 333-436) were mutated to every other amino acid.

Timothy Whitehead

Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:

Sept. 13, 2021

Academic Institutions and Nonprofits only

#174294

This library contains mutations to SARS-CoV-2 Spike RBD E484K variant in which all surface exposed residues on S RBD (Tile 2, positions 437-527) were mutated to every other amino acid.

Timothy Whitehead

Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:

Sept. 13, 2021

Academic Institutions and Nonprofits only

#174293

This library contains mutations to SARS-CoV-2 Spike RBD E484K variant in which all surface exposed residues on S RBD (Tile 1, positions 333-436) were mutated to every other amino acid.

Timothy Whitehead

Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:

Sept. 13, 2021

Academic Institutions and Nonprofits only

#136478

Expresses gRNAs for gene titration of ~2400 human genes using CRISPRi

Jonathan Weissman

Jost et al Nat Biotechnol. 2020 Jan 13. pii: 10.103

Feb. 25, 2020

Academic Institutions and Nonprofits only

#237473

Enables high-throughput identification of frame-preserving exons that influence transcriptional phenotypes, building on the CHyMErA system (Nature Biotechnology, 2020; PMID: 32249828).

Thomas Gonatopoulos-Pournatzis

Oct. 28, 2025

Academic Institutions and Nonprofits only

#232068

The CRASP-Seq backbone is designed to accommodate the cloning of diverse gRNA libraries. It includes a cell barcode (CBC), which enhances its functionality by enabling library preparation.

Thomas Gonatopoulos-Pournatzis

Behera et al bioRxiv [Preprint]. 2025 Apr 26:2025.04.

Oct. 28, 2025

Academic Institutions and Nonprofits only