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Showing: 121 - 140 of 174 results

Results per page:

hCRISPRi_dual_5_6

Pooled Library

#187248

Purpose

Ultra-compact, human genome-wide CRISPRi library targeting each gene with a single element encoding a dual sgRNA cassette.

Depositor

Jonathan Weissman, Marco Jost

Article

Replogle et al Elife. 2022 Dec 28;11:e81856. doi: 10.75

Species

Synthetic

Use

Lentiviral

Availability

Academic Institutions and Nonprofits only
hCRISPRa_dual_1_2

Pooled Library

#187249

Purpose

Ultra-compact, human genome-wide CRISPRi library targeting each gene with a single element encoding a dual sgRNA cassette.

Depositor

Jonathan Weissman, Marco Jost

Article

Replogle et al Elife. 2022 Dec 28;11:e81856. doi: 10.75

Species

Synthetic

Use

Lentiviral

Availability

Academic Institutions and Nonprofits only
hCRISPRa_dual_3_4

Pooled Library

#187250

Purpose

Ultra-compact, human genome-wide CRISPRi library targeting each gene with a single element encoding a dual sgRNA cassette.

Depositor

Jonathan Weissman, Marco Jost

Article

Replogle et al Elife. 2022 Dec 28;11:e81856. doi: 10.75

Species

Synthetic

Use

Lentiviral

Availability

Academic Institutions and Nonprofits only
hCRISPRa_dual_5_6

Pooled Library

#187251

Purpose

Ultra-compact, human genome-wide CRISPRi library targeting each gene with a single element encoding a dual sgRNA cassette.

Depositor

Jonathan Weissman, Marco Jost

Article

Replogle et al Elife. 2022 Dec 28;11:e81856. doi: 10.75

Species

Synthetic

Use

Lentiviral

Availability

Academic Institutions and Nonprofits only
Human CRISPR Knockout Pooled Library (H3)

Pooled Library

#133914

Purpose

CRISPR gRNA knockout pooled library for targeting the human genome - version H3

Depositor

Myles Brown, Xiaole Shirley Liu

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Availability

Academic Institutions and Nonprofits only
LX-miR

Pooled Library

#112200

Purpose

gRNA library targets human primary miRNAs

Depositor

Ren-Jang Lin

Article

Kurata et al RNA. 2018 May 2. pii: rna.066282.118. do

Expression

Mammalian

Species

Homo sapiens

Use

Lentiviral

Availability

Academic Institutions and Nonprofits only
Inzolia library in pRDA_052

Pooled Library

#209551

Purpose

The human, genome-wide, CRISPR knockout enAsCas12a gRNA library targets single genes and paralog pairs, triples, and quads with arrays of 4 gRNAs.

Depositor

John Doench

Article

Anvar et al bioRxiv. 2023 Sep 5:2023.01.03.522655. d

Use

CRISPR and Lentiviral

Availability

Academic Institutions and Nonprofits only
Inzolia library in pRDA_550

Pooled Library

#209552

Purpose

The human, genome-wide, CRISPR knockout enAsCas12a gRNA library targets single genes and paralog pairs, triples, and quads with arrays of 4 gRNAs.

Depositor

John Doench

Article

Anvar et al bioRxiv. 2023 Sep 5:2023.01.03.522655. d

Use

CRISPR and Lentiviral

Availability

Academic Institutions and Nonprofits only
mU6-CR1-CRISPRiv2_hU6-CR3-EMC2-guide_EF1a-PuroR-T2A-BFP

Pooled Library

#197349

Purpose

To allow for genome-wide genetic modifier screening, the library has a second fixed guide targeting EMC2.

Depositor

Jonathan Weissman, Rebecca Voorhees

Article

Guna et al bioRxiv. 2023 Jan 22:2023.01.22.525086.

Species

Homo sapiens

Use

Lentiviral

Availability

Academic Institutions and Nonprofits only
Pan-cancer CasRx lncRNA Albarossa library

Pooled Library

#212966

Purpose

The human CasRx CRISPR lentiviral library encodes 75,725 gRNA arrays (two gRNAs per array) targeting 24,171 lncRNAs.

Depositor

Roland Rad

Article

Montero et al Nat Methods. 2024 Feb 26. doi: 10.1038/s

Expression

Mammalian

Use

CRISPR and Lentiviral

Availability

Academic Institutions and Nonprofits only
mU6-CR1-CRISPRiv2_hU6-CR3-NT-ctrl-guide_EF1a-PuroR-T2A-BFP

Pooled Library

#197348

Purpose

To allow for genome-wide genetic modifier screening, the library has a second fixed non-targeting control guide.

Depositor

Jonathan Weissman, Rebecca Voorhees

Article

Guna et al bioRxiv. 2023 Jan 22:2023.01.22.525086.

Species

Homo sapiens

Use

Lentiviral

Availability

Academic Institutions and Nonprofits only
Oxford Drosophila melanogaster Genome-wide CRISPR Library

Pooled Library

#64750

Purpose

A genome-wide CRISPR library covering 13,501 genes (98.8% of the Drosophila melanogaster genome), among which 8,989 genes are targeted by three or more independent single guide RNAs (sgRNAs).

Depositor

Ji-Long Liu

Article

Bassett et al J Genet Genomics. 2015 Jun 20;42(6):301-

Expression

Insect

Species

Drosophila melanogaster, Streptococcus pyogenes, and Synthetic

Use

CRISPR

Availability

Academic Institutions and Nonprofits only
Splicing-targeting CRISPR-Cas9 library for human lncRNAs

Pooled Library

#119977

Purpose

The CRISPR sgRNA library was designed to target the 5' or 3' splice sites of lncRNAs in genome-scale, in order to knockout the targeted lncRNAs.

Depositor

Wensheng Wei

Article

Liu et al Nat Biotechnol. 2018 Nov 5. pii: nbt.428

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Availability

Academic Institutions and Nonprofits only
Human CRISPR Poison Exon Knockout Library

Pooled Library

#138084

Purpose

The human pgPoison library induces skipping of “poison” cassette exons and corresponding upstream constitutive exons by targeting 3' splice sites with paired gRNAs (pgRNAs).

Depositor

Robert Bradley

Article

Thomas et al Nat Genet. 2020 Jan;52(1):84-94. doi: 10

Species

Homo sapiens

Use

CRISPR and Lentiviral

Availability

Academic Institutions and Nonprofits only
MinLibCas9

Pooled Library

#164896

Purpose

Human genome-wide CRISPR-Cas9 gRNA library, optimised by mining existing large-scale screening datasets, which provides a >60% reduction in size while preserving key information content

Depositor

Mathew Garnett

Article

Goncalves et al Genome Biol. 2021 Jan 21;22(1):40. doi:

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Availability

Academic Institutions and Nonprofits only
Human SLC SAM Library

Pooled Library

#132561

Purpose

Expresses gRNAs for activation of human Solute Carrier family genes

Depositor

Giulio Superti-Furga

Article

Rebsamen et al Life Sci Alliance. 2022 Sep 16;5(11):e20

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Availability

Academic Institutions and Nonprofits only
Liu Lab MusCK Library A

Pooled Library

#174196

Purpose

MusCK library contains 23,622 unique sgRNAs targeting 4,787 gene locations in the genome. Sub-library MusCK A contains 5 gRNAs per gene.

Depositor

Xiaole Shirley Liu

Article

Wang et al Cell. 2021 Oct 14;184(21):5357-5374.e22.

Expression

Mammalian

Species

Mus musculus

Use

CRISPR and Lentiviral

Availability

Academic Institutions and Nonprofits only
Liu Lab MusCK Library B

Pooled Library

#174197

Purpose

MusCK library contains 23,622 unique sgRNAs targeting 4,787 gene locations in the genome. Sub-library MusCK M_b contains 5 gRNAs per gene.

Depositor

Xiaole Shirley Liu

Article

Wang et al Cell. 2021 Oct 14;184(21):5357-5374.e22.

Expression

Mammalian

Species

Mus musculus

Use

CRISPR and Lentiviral

Availability

Academic Institutions and Nonprofits only
ALL-PAM sensor Library

Pooled Library

#179219

Purpose

10 human and mouse sgRNAs each where for each sgRNA the tethered target site has 1 of 64 possible 3 bp PAM sequences.

Depositor

Lukas Dow

Article

Sanchez-Rivera et al Nat Biotechnol. 2022 Feb 14. pii: 10.103

Expression

Mammalian

Use

Lentiviral

Availability

Academic Institutions and Nonprofits only
Toronto KnockOut Library (TKOv1)

Pooled Library

#1000000069

Purpose

CRISPR gRNA knockout pooled library for targeting the human genome

Depositor

Jason Moffat, Stephane Angers

Availability

Academic Institutions and Nonprofits only

Showing: 121 - 140 of 174 results

Results per page:

hCRISPRi_dual_5_6

hCRISPRa_dual_1_2

hCRISPRa_dual_3_4

hCRISPRa_dual_5_6

Human CRISPR Knockout Pooled Library (H3)

LX-miR

Inzolia library in pRDA_052

Inzolia library in pRDA_550

mU6-CR1-CRISPRiv2_hU6-CR3-EMC2-guide_EF1a-PuroR-T2A-BFP

Pan-cancer CasRx lncRNA Albarossa library

mU6-CR1-CRISPRiv2_hU6-CR3-NT-ctrl-guide_EF1a-PuroR-T2A-BFP

Oxford Drosophila melanogaster Genome-wide CRISPR Library

Splicing-targeting CRISPR-Cas9 library for human lncRNAs

Human CRISPR Poison Exon Knockout Library

MinLibCas9

Human SLC SAM Library

Liu Lab MusCK Library A

Liu Lab MusCK Library B

ALL-PAM sensor Library

Toronto KnockOut Library (TKOv1)

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