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We narrowed to 752 results for: SON;

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Showing: 51 - 100 of 752 results

  1. Neurodegeneration Research Collection

    Type
    Collection
    ...nerve cell function within the cell. Parkinson's Disease Parkinson’s disease (PD) is a chronic and progressive...neurodegenerative diseases include Alzheimer’s, Parkinson’s, ALS, and Huntington’s Disease. These diseases...as early-onset, where symptoms appear between a person’s thirties and mid-sixties, or late-onset, where...where symptoms appear during or after a person's mid-sixties. The early-onset form accounts for less than...created with support from the BRAIN Initiative. Jackson Laboratory (Link opens in a new window) A collection...A foundation dedicated to finding a cure for Parkinson's disease through an aggressively funded research... of improved therapies for those living with Parkinson's today. The Michael J. Fox Foundation has made...

  2. New England Biolabs Cell-Imaging Plasmid Collection

    Type
    Collection
    ...website. For a comprehensive comparison to GFP, please refer to NEB's comparison of SNAP-tag, CLIP-tag, and...1998) References George N, Pick H, Vogel H, Johnsson N, Johnsson K. 2004. Specific labeling of cell surface...9712910 Vivero-Pol L, George N, Krumm H, Johnsson K, Johnsson N. 2005. Multicolor imaging of cell surface...

  3. Retrograde AAV viral preps

    Type
    Collection
    ...James M. Wilson 105553 pENN.AAV.hSyn.Cre.WPRE.hGH Syn Cre expression Recombinases James M. Wilson 105558...pENN.AAV.EF1a.eGFP.WPRE.rBG EF1a EGFP Control James M. Wilson 116869 pAAV-CAG-H2B-GFP CAG GFP Control Loren Looger...EGFP-tagged Cre expression Recombinases James M. Wilson 105551 pENN.AAV.CamKII.HI.GFP-Cre.WPRE.SV40 CamKII...Cre.SV40 CamKII Cre expression Recombinases James M. Wilson 107738 pAAV-hSyn-Cre-P2A-dTomato Syn Cre expression...AAV.rTH.PI.Cre.SV40 rTH Cre expression Recombinases James M. Wilson 55634 pAAV-EF1a-mCherry-IRES-Flpo EF1a Flpo and...Activator Optogenetics Edward Boyden 59171 pAAV-Syn-ChrimsonR-tdT Syn Activator Optogenetics Edward Boyden 83898...

  4. Fluorescent Protein Guide: Empty Backbones

    Type
    Collection
    ...Structure Plasmids mCrimson3 588 615 Monomer mCrimson3-N1 - Mammalian Expression mCrimson3-C1 - Mammalian ...Mammalian Expression E2-Crimson 611 646 29 4.5 24 min Tetramer pAAV-CAG-E2-Crimson - Mammalian AAV Expression...Expression pEB2-E2-Crimson - Bacterial Expression TagRFP657 611 657 0.34 5.3 27 min Prone to dimerization...Resources Addgene Collections Empty Backbones Michael Davidson Fluorescent Protein Collection Luciferase Plasmid...

  5. Adeno-associated virus (AAV) Plasmids

    Type
    Collection
    ...James M. Wilson 112864 pAAV2/8 AAV8 AAV packaging plasmid, expressing Rep2 and Cap8 James M. Wilson 112865...packaging plasmid, expressing Rep2 and Cap1 James M. Wilson 232199 pAAV2/2 AAV2 AAV packaging plasmid, expressing...packaging plasmid, expressing Rep2 and Cap9 James M. Wilson 240486 pAAV2/11 v1 AAV11 AAV packaging plasmid,...plasmid, expressing Rep2, and rh10 capsid James M. Wilson 81070 rAAV2-retro helper AAV retrograde AAV packaging...

  6. Antibody Guide

    Type
    Collection
    ...using sonication to break DNA up into fragments of 300-1000 bps in length. Note: This sonication process...may need additional processing steps, such as sonication. Denature proteins, using heat and/or chemicals...housekeeping genes). This allows for relative comparison of expression between different samples, by normalizing...normalizing protein expression to the controls before comparison. Alternatively, the samples can be normalized...ChIP protocols use enzyme digestion instead of sonication. This approach is gentler but results in non-...isolated and analyzed. Validation relies on size comparison of peptides. Independent antibody validation ...

  7. Rett Syndrome

    Type
    Collection
    ...Link opens in a new window) PMID: 17289941 2010 - Allyson Muotri's lab develops the first iPSC model for ...window) PMID: 26944080 (Link opens in a new window) Alysson Muotri Q83X C247T Q83X M Fibroblasts & iPSC (Link...window) PMID: 26944080 (Link opens in a new window) Alysson Muotri c.806delG 806delG G269Afs*20 M Fibroblasts...patient-derived iPSCs (Link opens in a new window) Jackson Labs - mouse line developer and repository, and...Pediatr Neurol . 52, 585-591.e2. PMID: 25801175 Tillotson and Bird. 2019. The Molecular Basis of MeCP2 Function...

  8. Michael J Fox Foundation (MJFF) Plasmid Collection

    Type
    Collection
    ... Collections MJFF Parkinson's Plasmid Resource Michael J. Fox Foundation Parkinson's Disease Plasmid Resource...Browse plasmids expressing genes relevant to Parkinson's disease created by the Michael J. Fox Foundation... researchers to assemble and share tools for Parkinson's disease research. This collection is part of ...

  9. Plasmids for Stem Cell Research

    Type
    Collection
    ...patient-specific or disease-specific cells. For this reason, iPSCs have become an excellent unlimited stem ...Cells. Science. 2007 Dec 21;318(5858):1917-20. Thomson Lentivirus Human Doxycycline-inducible expression...piggyBac Mouse Doxycycline-inducible piggyBac transposon reprogramming system; expression of mouse Oct4... pii: cells9112451. doi: 10.3390/cells9112451. Ottosson Stem Cell Research Plasmids This table contains...

  10. Genetic Code Expansion

    Type
    Collection
    ...synthetase M. maripaludis phosphoserine Bacterial Jason W Chin 174078 pDule-3-nitroTyrosine (A7) 3NY (A7...MmPylRS_MmtRNA-Pyl-opt(UGA) PylRS M. mazei Bacterial TGA Jason W Chin 174516 pMB1_1R26PylRS(CbzK)_AfTyrRS(p-I-Phe... AfTyrRS CbzK and p-I-Phe Bacterial TCG and TAG Jason W Chin 174718 pRSF-G1mCNPRS G1mCNPRS Methanogenic...coumarin-yl) ethylglycine Bacterial TAG Kenneth Johnson 198323 pRSF-G1TMSNKRS M. archaeon TMSNK Bacterial..., TCA, or TAG codons in all open reading frames Jason W Chin 174514 Syn61Δ3(ev5) No TCG, TCA, or TAG codons... codons. Deletion of serT, serU, and prfA genes Jason W Chin 182773 C321.∆A ompT- rne- lon- Recoded E....

  11. Chemogenetics AAV Preps

    Type
    Collection
    ... Inhibition IRES EGFP Cre-dependent 5, 9 Scott Sternson 119742 AAV SYN PSAM4 GlyR IRES EGFP PSAM4 GlyR...GlyR - Inhibition IRES EGFP none 5 Scott Sternson 119744 AAV CAMKII PSAM4 GlyR IRES EGFP PSAM4 GlyR - Inhibition...Inhibition IRES EGFP none 5 Scott Sternson 121538 pAAV SYN1 HA-hM4D(Gi) hM4D(Gi) - Inhibition HA fusion...hM4D(Gi) - Inhibition GFP Cre-dependent 1 Scott Sternson 228902 pAAV-CAG-DIO-HA-HCARD-P2A-mCitrine HCAD...

  12. Fluorescent Proteins: FRET

    Type
    Collection
    ...Additional Resources Förster (or Fluorescence) Resonance Energy Transfer (FRET) is a process by which energy...multiphoton spectral imaging and its use for measuring resonance energy transfer mCerulean, mVenus, and Amber (... positive controls for many FRET pairs Michael Davidson Lab (Unpublished) FRET Indicators - Live and Fixed...fluorescent protein acceptor for Bioluminescence Resonance Energy Transfer (BRET) . Browse Addgene's Luciferase...

  13. Deisseroth INTRSECT Collection

    Type
    Collection
    ...Berndt A, Grosenick L, Zalocusky KA, Bernstein H, Swanson H, Perry C, Diester I, Boyce FM, Bass CE, Neve ...opens in a new window) Wick ZC, Tetzlaff MR, Krook-Magnuson E. 2019. A novel population of long-range inhibitory...Tzortzi O, Weglage M, Märtin A, Xuan Y, Parent M, Johansson Y, Fuzik J, Fürth D, Fenno LE, Ramakrishnan C,...Hyun M, Umadevi Venkataraju K, Straub C, Wang W, Robertson K, Osten P, Sabatini BL. 2019. Distinct Cortical-Thalamic-Striatal...

  14. Fluorescent Protein Guide: Biosensors

    Type
    Collection
    ...permuted fluorescent protein (cpFP) or fluorescence resonance energy transfer (FRET) efficiency of a pair of...locations. PLoS One. 2012;7(11):e49371. Direct comparison of a genetically encoded sensor and small molecule... levels and metabolism (FLIPmal) Fluorescence Resonance Energy Transfer sensors for quantitative monitoring... Science. 2018 Sep 14;361(6407):1122-1126. Kai Johnsson NADPH/NADP+ or NAD+ Snifit FRET-based sensors ...dinucleotides. eLife. 2018 May 29;7. pii: 32638. Kai Johnsson NADPH/NADP+ NAPstar biosensors for NADPH/NADP+...Am Chem Soc. 2012 Nov 21;134(46):19026-34. Kai Johnsson Glutamate Fourth generation glutamate sensors ...

  15. The Pleiades Promoter Project

    Type
    Collection
    ...intron-lacZ/NLS References Portales-Casamar, E., Swanson, D. J., Liu, L., de Leeuw, C. N., Banks, K. G.,... Palma, B., Palmquist, D. L., Schmouth, J. F., Swanson, M. I., Tam, B., Ticoll, A., Turner, J. L., Varhol...Varhol, R., Vermeulen, J., Watkins, R. F., Wilson, G., Wong, B. K., Wong, S. H., Wong, T. Y., Yang, G. ... Holt, R. A., Goldowitz, D., Wasserman, W. W., Simpson, E. M. (2010). A regulatory toolbox of MiniPromoters...

  16. Caltech Systemic Capsids

    Type
    Collection
    ... CMV EGFP Control Wilson 105547 pENN.AAV.EF1a.eGFP.WPRE.rBG EF1a EGFP Control Wilson 114469 pAAV-CaMKIIa-mCherry...Cre-EGFP expression Cre Wilson 105550 pAAV.GFAP.Cre.WPRE.hGH GFAP Cre-expression Cre Wilson 107738 pAAV-hSyn-...

  17. Tetracycline Inducible Expression

    Type
    Collection
    ...et al., 2016 (Link opens in a new window) for comparison of Tet-On systems in different applications. ...Johannes Zuber 60495 pSBtet-GP Sleeping Beauty transposon system with luciferase in cloning site. See article...inducible expression of EGFP Tet-On 3G rtTA TRE3GS Jason Sheltzer 11651 pLVUT-tTR-KRAB Lentiviral Tet-On ...R., & Schiedlmeier, B. (2011). Retroviral and transposon-based tet-regulated all-in-one vectors with reduced...

  19. Distribution to Industry

    Type
    Collection
    ...CRISPR tools Fluorescent Proteins from the Michael Davidson collection Protein Labeling from New England Biolabs...RESOLUTE collection AAV Packaging from Addgene Parkinson's Research from The Michael J Fox Foundation Search...Screening Messer and MJFF Created for research in Parkinson's Disease; For target validation and drug design...

  20. Zebrafish Plasmid Collection

    Type
    Collection
    ...standard toolbox of genetic methods, such as Tol2 transposons, Cre-mediated site-specific recombination, morpholinos... expression system for use in zebrafish - Bret Pearson Lab MAZe: a tool for mosaic analysis of gene function...digital spectral barcodes for cell tracing - Sean Megason Lab Zebrabow - Albert Pan and Alex Schier Labs....

  21. Plant Plasmids and Resources

    Type
    Collection
    ...Includes modules for CRISPR/Cas9 genome editing, dexamethasone-inducible expression, and fluorescent plasma...Fluorescence Complementation (rBiFC) and Förster Resonance Energy Transfer (FRET). Gateway Christopher Grefen...

  22. Luciferase Plasmid Collection

    Type
    Collection
    ... expression of firefly luciferase and GFP James Wilson 22522 phGluc Gaussia EF1α Expression of Gaussia... CMV AAV expression of firefly luciferase James Wilson 101156 T7-CMVtrans-FFLuc-polyA Firefly T7 Expression...complementation assays in plants. Bioluminescence Resonance Energy Transfer (BRET) Similar to FRET, energy...

  23. Plan Your Experiment

    Type
    Collection
    .... D., Dionne, D., Burks, T., Raychowdhury, R., Adamson, B., Norman, T. M., Lander, E. S., Weissman, J....PMID: 35941224 Gilbert, L. A., Horlbeck, M. A., Adamson, B., Villalta, J. E., Chen, Y., Whitehead, E. H...s41594-023-01090-9 PMID: 37783853 Zuris, J. A., Thompson, D. B., Shu, Y., Guilinger, J. P., Bessen, J. ...

  24. Biosensor AAV Preps

    Type
    Collection
    ...GENIE Project 174007 pAAV-hSyn-DIO-jGCaMP8s-P2A-ChrimsonR-ST Syn jGCaMP8s none Cre-dependent 9 Mark Histed...CamKII GCaMP6f none Constitutive 1, 5, 9 James M. Wilson 100835 pAAV.CAG.Flex.GCaMP6f.WPRE.SV40 CAG GCaMP6f...AAV.CamKII.GCaMP6s.WPRE.SV40 CamKII GCaMP6f none Constitutive 9 James M. Wilson 111262 pAAV-hSynapsin1-axon-GCaMP6s Syn axon-GCaMP6s...

  25. KLF Research Plasmids

    Type
    Collection
    ...Rudolf Jaenisch Keisuke Kaji Jonathan Katz Nathan Lawson Kathrin Plath Miguel Ramalho-Santos Derrick Rossi...Rossi Michael Ruppert Michel Sadelain James Thomson Tim Townes Robert Weinberg Knut Woltjen Shinya Yamanaka...

  26. Depositor Collections

    Type
    Collection
    ...TREAT-AD Plasmid Collection Visualization Michael Davidson Fluorescent Protein Collection Allen Institute...mini-promoters to drive selective expression in the brain - Simpson Reagents for improved expression of recombinant...

  27. Brzezinski Lab CRISPR Collection

    Type
    Collection
    ...Plasmid Description PI Publications Kaufman, M. L., Goodson, N. B., Park, K. U., Schwanke, M., Office, E., ...148(12). doi: 10.1242/dev.199399. PMID: 34143204 Goodson, N. B., Kaufman, M. A., Park, K. U., & Brzezinski...

  28. Addgene Packaged on Request: Scope of Service

    Type
    Collection
    ...prep, mostly likely due to one of the following reasons: Transfer plasmids with sequence from the 5′ to...that may reduce titer due to toxicity or other reasons For these cases, Addgene will promptly notify you...

  29. Synthetic Biology - Overview

    Type
    Collection
    ...Engineering SynBio Depositing Labs Hal Alper J. Chris Anderson Adam Arkin Gabor Balazsi Matthew Bennett Carolyn...SynBio Deposits Alper Lab Y. Lipolytica Promoters Anderson Lab Plasmids and Phagemids Balazsi Lab Negative...

  30. Resolute Plasmid Collection

    Type
    Collection
    ... A., Insidioso, M., Maresca, G., Redaelli, L., Sassone, F., Scarabottolo, L., Stucchi, M., Tarroni, P....., Santacruz, D., Viollet, C., Whitehurst, C., Johnsson, K., Leippe, P., Baumgarten, B., Chang, L., Ibig...

  31. AAV Molecular Tools

    Type
    Collection
    ...pAAV-CamkII-tTA-2A-E2-Crimson-WPRE-pA CamKIIa Expression of tet-off transactivator (tTA) and E2 Crimson. 8 Jonathan...

  32. COVID-19 Resources

    Type
    Collection
    ... the entry of SARS-CoV and SARS-CoV-2 viruses (Anderson et al., 2020). TMPRSS2 plasmids - a serine protease...a potential cleavage site for furin proteases (Anderson et al., 2020). BSG plasmids - (CD147), transmembrane...

  33. TALEN Plasmids and Kits

    Type
    Collection
    ...Gate TALEN 2.0 38142 RCIscript-GoldyTALEN Daniel Carlson The plasmids pC-GoldyTALEN and RCIsricpt-GoldyTALEN...Lab TALE Toolbox 49622 - 49647 24 plasmids Thoru Pederson TALEColor plasmids: destination vectors for use...

  34. CRISPR References and Information

    Type
    Collection
    ...Proof-of-concept performed in zebrafish. Developed by the Jason Berman Lab . CRISPRdirect (Link opens in a new window... cloning into pLX-sgRNA pLX-sgRNA PDF, 129 KB Sontheimer gRNA design and cloning All-in-one plasmid containing...

  35. Zhang Lab CRISPR Page

    Type
    Collection
    .... The Cas9 knockin mouse can be purchased from Jackson Labs: Cre-dependent Cas9 mouse Constitutively active...Jhunjhunwala S, Heidenreich M, Xavier RJ, Langer 9, Anderson DG, Hacohen N, Regev A, Feng G, Sharp PA, Zhang...

  36. NETRF

    Type
    Collection
    ...Using Adult Stem Cell-Derived Organoids Matthew Meyerson Dana-Farber Cancer Institute Finding the Causes...

  37. Fluorescent Protein Guide

    Type
    Collection
    ...by fusing it to a fluorescent protein. Michael Davidson Fluorescent Protein Collection Browse this extensive...

  40. TALEN Engineering

    Type
    Collection
    ... ( Sander et al., Nat Biotechnol. 2011 ) Rats ( Tesson et al., Nat Biotechnol. 2011 ) Human somatic cells...

  41. Chemogenetics Plasmids

    Type
    Collection
    ...search for "hM4D mCherry", "KORD AAV", "LMO", "Sternson", or other terms. Looking for viral preps? We ...

  42. Mammalian RNAi Tools

    Type
    Collection
    ...Andrea Ventura lab) References Carthew, R. W., & Sontheimer, E. J. (2009). Origins and mechanisms of miRNAs...

  45. Antibody Plasmid Collection

    Type
    Collection
    ...analysis of scFv antibody fragments selected from Tomlinson I+J phagemid libraries. Immunol Lett. 2015 Oct...

  46. mTOR Pathway

    Type
    Collection
    ...machinery in cancer. Bhat M, Robichaud N, Hulea L, Sonenberg N, Pelletier J, Topisirovic I. Nat Rev Drug Discov...

  47. p53 Pathway

    Type
    Collection
    ..., Lu X, Soron G, Cooper B, Brayton C, Park SH, Thompson T, Karsenty G, Bradley A, Donehower LA. Nature...

  48. TALEN Guide

    Type
    Collection
    ...TALENs. Sander JD, Cade L, Khayter C, Reyon D, Peterson RT, Joung JK, Yeh JR. Nat Biotechnol. 2011 Aug...

  49. Lentivirus Plasmids

    Type
    Collection
    ...pLVX-TetOne-Puro-GFP 3rd Dox-inducible expression of GFP. Jason Sheltzer 20342 FUW-M2rtTA 3rd Contains reverse tetracycline...
Showing: 51 - 100 of 752 results