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Addgene's collection of synthetic biology plasmids related to Networks and Gene Regulation

CRISPR plasmids that have been designed for use in Drosophila and other insects.

CRISPR plasmids with dCas9 fused to FokI for creating double-strand breaks (DSBs).

Synthetic Biology plasmids for cloning and genomic tools.

CRISPR plasmids for transcriptional repression of target genes.

CRISPR expression plasmids that have been designed for use in plants.

CRISPR plasmids that have been designed for use in yeast.

CRISPR plasmids based on Cas13 designed to precisely edit RNA targets.

CRISPR plasmids for targeted epigenetic modification, including histone acetylation/demethylation, and cytosine methylation/demethylation.

CRISPR expression plasmids that have been designed for use in parasites.

Browse mitogen-activated protein kinase (MAPK) plasmids.

CRISPR plasmids for activating or upregulating gene expression in various model organisms.

CRISPR plasmids that have been designed for use in bacteria.

Empty gRNA expression vectors for insertion of custom gRNA target sequences.

CRISPR nickase plasmids for the generation of single-strand breaks.

CRISPR plasmids for targeting RNA sequences, which include the enzymes C2c2/Cas13a and Cas13b.

CRISPR plasmids that have been designed for use in mammalian systems.

Browse the Zhang lab’s comprehensive human transcription factor collection, available at Addgene. The collection can be used for screening transcription factors for cellular programming or cancer drug resistance.

Catalytically inactive CRISPR plasmids for purification of target loci.

In our Antibody Guide, we define key terms, summarize antibody production and storage techniques, and explain common applications.