We narrowed to 37 results for: atic
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TypeCollection...iPSCs or transdifferentiation of a somatic cell to a new type of somatic cell. Sort the table by cell type...reprogramming of adult pancreatic exocrine cells to beta-cells. Nature. 2008 Aug 27. Melton Pancreatic Acinar Cells...body. Multipotent stem cells, such as adult (or somatic) stem cells, can differentiate into multiple cell.... To create iPSCs, fully-differentiated adult somatic cells are returned to a pluripotent state using...they can be directly differentiated into specific somatic stem cells or fully differentiated cell types. ...possible to directly differentiate one differentiated somatic cell into another via transdifferentiation. This...Pluripotent Stem Cell Lines Derived from Human Somatic Cells. Science. 2007 Dec 21;318(5858):1917-20. ...
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CRISPR Guide
TypeCollection...a wide spectrum of single-nucleotide variants (somatic hypermutation) in a larger editing window. These...recommended in contexts where such mutations would be problematic. Browse Plasmids: Base Edit CRISPR Prime Editing... Cas nucleases dCas9 Nuclease dead Cas9, an enzymatically inactive form of Cas9; can bind, but cannot ...2016). Directed evolution using dCas9-targeted somatic hypermutation in mammalian cells. Nature Methods...Bintu, L., Bhatt, A. S., & Hsu, P. D. (2022). Systematic discovery of recombinases for efficient integration... -
NETRF
TypeCollection... and more effective treatments for carcinoid, pancreatic, and related neuroendocrine cancers. The NETRF...States and Drivers in Intestinal Carcinoid and Pancreatic Neuroendocrine Tumors... -
AAV for Neuronal Tracing
TypeCollection...from Addgene's viral service encoding tools for monosynpatic retrograde neuronal tracing, to be used with...cells engineered to express TVA will be infected. Schematic depicting steps for using AAV and modified rabies... -
CRISPR Plasmids - Tagging
TypeCollection...System Geraldine Seydoux's lab has developed a systematic and scalable method to create marker-free mutations...markers or footprints, and can be scaled up for systematic editing of multiple genes. Plasmids can be found... -
Brain Initiative Collection
TypeCollection...Adesnik 107708-AAV9 pAAV-hSynapsin- soCoChR-GFP A somatic channelrhodopsin, which enables single cell, single... 107712-AAV9 pAAV-hSynapsin-FLEX-soCoChR-GFP A somatic channelrhodopsin, which enables single cell, single... -
Fluorescent Protein Guide: Biosensors
TypeCollection...Indicators to Image Dynamic Zn(2+) Secretion of Pancreatic Islets. Anal Chem. 2019 Oct 1;91(19):12212-12219...One. 2014 Oct 23;9(10):e110600. Isei Tanida Electrostatic potential Quantitative measurements of membrane... -
iPSC Neurodegenerative Disease Initiative Plasmid Collection
TypeCollection...iNDI plasmid collection at Addgene. Figure 1: Schematic of iNDI iPSC line generation, phenotyping, and... -
Impact of Genomic Variation on Function (IGVF) Consortium Collection
TypeCollection... collection will grow as the IGVF community systematically perturbs the genome to assess the impact of... -
Cancer Research Plasmids and Resources
TypeCollection...initial Target Accelerator publications, focused on somatic variants found in lung adenocarcinoma as well as... -
CRISPR Plasmids - RNA Targeting
TypeCollection...cleaved the target RNA sequence, they adopt an enzymatically active state and can bind and cleave additional... -
Bikard Lab - CRISPR Repression Collection
TypeCollection...expression of two genes without crossâtalk. (A) Schematic of the strain expressing two reporters and dCas9... -
Brzezinski Lab CRISPR Collection
TypeCollection...activation CRISPR/Cas9 Plasmid Variants Figure 1: Schematic of the CRISPR Collection. Plasmids 159654 and ... -
TALEN Engineering
TypeCollection... ( Tesson et al., Nat Biotechnol. 2011 ) Human somatic cells ( Miller et al., Nat Biotechnol. 2011 ; Reyon... -
CRISPR Plasmids - Base Edit
TypeCollection...a wide spectrum of single-nucleotide variants (somatic hypermutation) in a wider editing window, and are... -
Malate Dehydrogenase CUREs Community Collection
TypeCollection...mentor, and more. References for teachers Using Bioinformatics and Molecular Visualization to Develop Student... -
Retrovirus Plasmids
TypeCollection...comprised of its genome and several structural and enzymatic proteins, including reverse transcriptase and ... -
New England Biolabs Cell-Imaging Plasmid Collection
TypeCollection...used exclusively for surface proteins and use enzymatic binding to attach substrate Control plasmids with... -
Promega Plasmid Collection
TypeCollection...window) reporter assays use light produced from an enzymatic reaction to measure subtle expression changes ... -
AAVED
TypeCollection...useful information. Experimental protocols or schematics. Examples of research materials to share: In ...