We narrowed to 470 results for: LEP

1. pSicoR-ATF7IPi2

   Plasmid

   #59615

   Purpose

   Expression of shRNA against human ATF7IP

   Depositor

   Miguel Ramalho-Santos

   Article

   Qin et al Cell. 2014 Jul 17;158(2):449-61. doi: 10

   Insert

   ATF7IP (ATF7IP Human)
   

   Use

   RNAi

   Expression

   Mammalian

   Promoter

   U6

   Available Since

   Oct. 1, 2014

   Availability

   Academic Institutions and Nonprofits only

2. pSicoR-MED19i1

   Plasmid

   #59632

   Purpose

   Expression of shRNA against human MED19

   Depositor

   Miguel Ramalho-Santos

   Article

   Qin et al Cell. 2014 Jul 17;158(2):449-61. doi: 10

   Insert

   MED19 (MED19 Human)
   

   Use

   RNAi

   Expression

   Mammalian

   Promoter

   U6

   Available Since

   Sept. 29, 2014

   Availability

   Academic Institutions and Nonprofits only

3. pIR-CMV-SCN2A-Variant-4-IRES-mScarlet

   Plasmid

   #209410

   Purpose

   Expression of wild-type neonatal isoform of human SCN2A.

   Depositor

   Al George

   Article

   Thompson et al bioRxiv. 2023 Feb 23:2023.02.23.529757.

   Insert

   SCN2A Variant 4, stabilized (SCN2A Human)
   

   Expression

   Mammalian

   Mutation

   IVS intron inserted after bp 4551 of the SCN2A OR…

   Promoter

   CMV

   Available Since

   Jan. 2, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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4. pCK033 p5E desma MCS

   Plasmid

   #195948

   Purpose

   Gateway p5E vector

   Depositor

   Christian Mosimann

   Article

   Kemmler et al Development. 2023 Mar 28:dev.201531. doi

   Insert

   desmin a regulatory elements (desma Zebrafish)
   

   Use

   Other

   Available Since

   Feb. 22, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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5. pLVX-opto-hCaspase-9

   Plasmid

   #208787

   Purpose

   Inducibly expresses human Caspase 8 fused to light-activatable Cry2

   Depositor

   Petr Broz

   Article

   Shkarina et al J Cell Biol. 2022 Jun 6;221(6). pii: 213

   Insert

   Caspase 9 (CASP9 Human)
   

   Use

   Lentiviral

   Expression

   Mammalian

   Available Since

   Nov. 2, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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6. Pomc-pGL3

   Plasmid

   #17553

   Purpose

   Luciferase expression under control of Pomc promoter (–646 to +65).

   Depositor

   Domenico Accili

   Article

   Kitamura et al Nat Med. 2006 May . 12(5):534-40.

   Insert

   Pomc promoter (Pomc Mouse)
   

   Use

   Luciferase

   Expression

   Mammalian

   Promoter

   Pomc

   Available Since

   Oct. 17, 2008

   Availability

   Academic Institutions and Nonprofits only

   

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7. pCMV-Myc CDC4 WT*

   Plasmid

   #16652

   Depositor

   Bert Vogelstein

   Article

   Rajagopalan et al Nature. 2004 Mar 4. 428(6978):77-81.

   Insert

   CDC4 (FBXW7 Human)
   

   Tags

   myc

   Expression

   Mammalian

   Mutation

   *Note that this insert is only WT relative to the…

   Available Since

   March 12, 2008

   Availability

   Academic Institutions and Nonprofits only

   

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8. pIRES2Cx32WTEGFP

   Plasmid

   #78150

   Purpose

   Mammalian Expression of Connexin 32 and EGFP from a bicistronic mRNA

   Depositor

   Mario Bortolozzi

   Article

   Carrer et al Hum Mol Genet. 2017 Oct 25. pii: 4565496

   Insert

   Connexin 32 (GJB1 Human)
   

   Tags

   EGFP

   Expression

   Mammalian

   Promoter

   CMV

   Available Since

   Dec. 4, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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9. pCK036 desmaMCS:minCerulean,cryaa:Venus

   Plasmid

   #195981

   Purpose

   Expression construct

   Depositor

   Christian Mosimann

   Article

   Kemmler et al Development. 2023 Mar 28:dev.201531. doi

   Insert

   desmin a regulatory elements, mouse beta-globin minimal promoter mCerulean, cryaa Venus (desma Zebrafish)
   

   Use

   Other

   Available Since

   Feb. 10, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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10. pKLV-EF1aGFP2AKAT7(E508Q)-W

    Plasmid

    #159293

    Purpose

    Lentiviral vector expressing GFP and KAT7 (gRNA-resistant, E508Q mutant) driven by human EF1a promoter

    Depositor

    Kosuke Yusa

    Article

    Au et al Leukemia. 2021 Apr;35(4):1012-1022. doi:

    Insert

    KAT7 E508Q
    

    Use

    Lentiviral

    Expression

    Mammalian

    Mutation

    CRISPR sites mutated (gRNA ID. 5 and A10) and E50…

    Promoter

    human EF1a promoter

    Available Since

    Dec. 3, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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11. pCK069 desmaMCS:minprom_mApple,exorh:EGFP

    Plasmid

    #195982

    Purpose

    Expression construct

    Depositor

    Christian Mosimann

    Article

    Kemmler et al Development. 2023 Mar 28:dev.201531. doi

    Insert

    desmin a regulatory elements, mouse beta-globin minimal promoter mApple, exorh:EGFP (desma Zebrafish)
    

    Use

    Other

    Available Since

    Feb. 10, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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12. pAGT6471

    Plasmid

    #219428

    Purpose

    Module of intronized NLS-SpCas9-NLS for N-terminal and C-terminal tag fusions (AGGT_N-SpCas9i-N_TTCG)

    Depositor

    Tom Schreiber

    Article

    Schreiber et al Mol Plant. 2024 Mar 22:S1674-2052(24)000

    Insert

    AGGT_NLS-SpCas9i-NLS(no stop)_TTCG
    

    Use

    Moclo compatible level 0 module

    Available Since

    July 2, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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13. pRCPam

    Plasmid

    #195861

    Purpose

    Encodes chromogenic protein (CP) with nonsense mutation resulting in amber stop codon at amino acid 62. CP inducible with rhamnose in amber suppressor strains.

    Depositor

    Gregory Phillips

    Article

    DeWolf et al J Microbiol Biol Educ. 2023 Oct 25;24(3)

    Insert

    Amber Chromogenic Protein on pRCPam plasmid
    

    Expression

    Bacterial

    Mutation

    Gln62X

    Available Since

    Feb. 8, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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14. GFP-CYLD-C601A

    Plasmid

    #60028

    Purpose

    N-terminal GFP tagged catalytic inactive (C601A) expression

    Depositor

    Stephen Elledge

    Article

    Stegmeier et al Proc Natl Acad Sci U S A. 2007 May 22. 1

    Insert

    Cylindromatosis (CYLD Human)
    

    Tags

    GFP

    Expression

    Mammalian

    Mutation

    Cysteine 601 changed to Alanine

    Promoter

    CMV

    Available Since

    Nov. 25, 2014

    Availability

    Academic Institutions and Nonprofits only

    

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15. pTRE-Tight-FLAG-CYLD-C601A

    Plasmid

    #60029

    Purpose

    CYLD (C601A) catalytic dead under control of Tet promoter with N-terminal FLAG tag

    Depositor

    Stephen Elledge

    Article

    Stegmeier et al Proc Natl Acad Sci U S A. 2007 May 22. 1

    Insert

    Cylindromatosis (CYLD Human)
    

    Tags

    FLAG

    Expression

    Mammalian

    Mutation

    Cysteine 601 changed to Alanine

    Promoter

    TRE

    Available Since

    Aug. 13, 2015

    Availability

    Academic Institutions and Nonprofits only

16. pcDNA3 FLAG CEP68

    Plasmid

    #236463

    Purpose

    transient overexpression of Cep68 in mammalian cells

    Depositor

    Michele Pagano

    Article

    Pagan et al Nat Cell Biol. 2015 Jan;17(1):31-43. doi

    Insert

    Cep68 (CEP68 Human)
    

    Expression

    Mammalian

    Available Since

    May 20, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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17. pCMV2-SEP-GluA1 (M1)

    Plasmid

    #64942

    Purpose

    mammalian expression of rat GluA1

    Depositor

    Jeremy Henley

    Article

    Blanco-Suarez et al J Biol Chem. 2014 Feb 21;289(8):4644-51.

    Insert

    GluA1 (Gria1 Rat)
    

    Tags

    SEP (superecliptic pHluorin)

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    May 14, 2015

    Availability

    Academic Institutions and Nonprofits only

    

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18. pIRES2-DsRed-MST-Kv2.1

    Plasmid

    #131707

    Purpose

    Expresses Kv2.1in mammalian cells

    Depositor

    Jennifer Kearney

    Article

    Jorge et al Proc Natl Acad Sci U S A. 2011 Mar 29;10

    Insert

    KCNB1 (KCNB1 Human)
    

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    Oct. 22, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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19. hKCNB1 L211P

    Plasmid

    #124487

    Purpose

    missense mutation in children with EOEE. HA tagged in C-terminus, pCIneo vector

    Depositor

    Federico Sesti

    Article

    Yu et al FASEB J. 2019 Dec;33(12):14680-14689. do

    Insert

    human KCNB1 (KCNB1 Human)
    

    Tags

    HA

    Expression

    Mammalian

    Mutation

    changed leucine 211 to proline

    Available Since

    Sept. 3, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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20. hKCNB1 G381R

    Plasmid

    #124490

    Purpose

    missense mutation in children with EOEE. HA tagged in C-terminus, pCIneo vector

    Depositor

    Federico Sesti

    Article

    Yu et al FASEB J. 2019 Dec;33(12):14680-14689. do

    Insert

    human KCNB1 (KCNB1 Human)
    

    Tags

    HA

    Expression

    Mammalian

    Mutation

    changed glycine at 381 to arginine

    Available Since

    Sept. 3, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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21. hKCNB1 F416L

    Plasmid

    #124491

    Purpose

    missense mutation in children with EOEE. HA tagged in C-terminus, pCIneo vector

    Depositor

    Federico Sesti

    Article

    Yu et al FASEB J. 2019 Dec;33(12):14680-14689. do

    Insert

    human KCNB1 (KCNB1 Human)
    

    Tags

    HA

    Expression

    Mammalian

    Mutation

    changed phenyalanine 416 to leucine

    Available Since

    Sept. 3, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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22. pC013 - Twinstrep-SUMO-huLwCas13a

    Plasmid

    #90097

    Purpose

    Twinstrep-SUMO-huLwCas13a for recombinant protein bacterial expression. Insert is human codon optimized but expresses well in bacteria.

    Depositor

    Feng Zhang

    Article

    Gootenberg et al Science. 2017 Apr 13. pii: eaam9321. doi

    Insert

    LwCas13a
    

    Use

    CRISPR

    Tags

    6xHis-Twin Strep-SUMO

    Expression

    Bacterial

    Available Since

    June 13, 2017

    Availability

    Industry, Academic Institutions, and Nonprofits

    

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23. pcDNA5FRT_KCNQ3

    Plasmid

    #173163

    Purpose

    To generate Flp-In CHO-KCNQ3 stable cells

    Depositor

    Al George

    Article

    Vanoye et al JCI Insight. 2022 Mar 8;7(5):e156314. do

    Insert

    KCNQ3 (KCNQ3 Human)
    

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    Sept. 16, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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24. Cx32R220stop

    Plasmid

    #78151

    Purpose

    Mammalian Expression of the first 219 amino acids of Connexin 32 and EGFP from a bicistronic mRNA

    Depositor

    Mario Bortolozzi

    Article

    Carrer et al Hum Mol Genet. 2017 Oct 25. pii: 4565496

    Insert

    Connexin 32 (GJB1 Human)
    

    Tags

    EGFP

    Expression

    Mammalian

    Mutation

    Only contains first 219 residues

    Promoter

    CMV

    Available Since

    Dec. 4, 2017

    Availability

    Academic Institutions and Nonprofits only

25. pAAV.E2.ChETA

    Plasmid

    #220310

    Purpose

    Directs ChETA optogenetic actuator to fast spiking interneurons in cortex. Allows for single APs to be evoked.

    Depositor

    Matt Rowan

    Article

    Kumar et al Nat Commun. 2024 Apr 1;15(1):2823. doi:

    Insert

    ChETA
    

    Use

    AAV

    Expression

    Mammalian

    Promoter

    S5E2

    Available Since

    June 28, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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26. MSCV-TAP(FLAG-HA) CYLD

    Plasmid

    #60031

    Purpose

    CYLD with N-terminal TAP-tag (HA,FLAG) and IRES-Puro to allow tagged protein to be maintained

    Depositor

    Stephen Elledge

    Article

    Stegmeier et al Proc Natl Acad Sci U S A. 2007 May 22. 1

    Insert

    Cylindromatosis (CYLD Human)
    

    Use

    Retroviral

    Tags

    FLAG, HA, and IRES Puro

    Expression

    Mammalian

    Promoter

    LTR-driven expression

    Available Since

    Feb. 24, 2016

    Availability

    Academic Institutions and Nonprofits only

27. pRC/RSV-rat Agt

    Plasmid

    #122104

    Purpose

    Expression of angiotensinogen

    Depositor

    John Chan

    Article

    Zhang et al J Am Soc Nephrol. 2002 Feb;13(2):302-12.

    Insert

    angiotensinogen (Agt Rat)
    

    Expression

    Mammalian

    Promoter

    RSV promoter

    Available Since

    July 15, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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28. PC1575

    Plasmid

    #232088

    Purpose

    Mammalian expression plasmid for ubiquibody (uAb) cloning backbone. Includes an Esp3I restriction site directly upstream of GSGSG linker and CHIPΔTPR CDS and a C-terminal IRES-mCherry cassette.

    Depositor

    Pranam Chatterjee

    Article

    Bhat et al Sci Adv. 2025 Jan 24;11(4):eadr8638. doi

    Insert

    uAb with cloning Esp3I restriction site
    

    Tags

    IRES-mCherry

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    April 24, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

29. hKCNB1 R312H

    Plasmid

    #124488

    Purpose

    missense mutation in children with EOEE. HA tagged in C-terminus, pCIneo vector

    Depositor

    Federico Sesti

    Article

    Yu et al FASEB J. 2019 Dec;33(12):14680-14689. do

    Insert

    human KCNB1 (KCNB1 Human)
    

    Tags

    HA

    Expression

    Mammalian

    Mutation

    changed arginine 312 to histidine

    Available Since

    Sept. 3, 2019

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

30. hKCNB1 G379R

    Plasmid

    #124489

    Purpose

    missense mutation in children with EOEE. HA tagged in C-terminus, pCIneo vector

    Depositor

    Federico Sesti

    Article

    Yu et al FASEB J. 2019 Dec;33(12):14680-14689. do

    Insert

    human KCNB1 (KCNB1 Human)
    

    Tags

    HA

    Expression

    Mammalian

    Mutation

    changed glycine at 379 to arginine

    Available Since

    April 16, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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31. p3E ubb polyA

    Plasmid

    #195977

    Purpose

    Gateway p3E vector

    Depositor

    Christian Mosimann, Alexa Burger

    Article

    Kemmler et al Development. 2023 Mar 28:dev.201531. doi

    Insert

    ubb:polyA (ubb Zebrafish)
    

    Use

    Other

    Available Since

    Feb. 24, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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32. pKLV-EF1aGFP2AKAT7-W

    Plasmid

    #159292

    Purpose

    Lentiviral vector expressing GFP and KAT7 (gRNA-resistant) driven by human EF1a promoter

    Depositor

    Kosuke Yusa

    Article

    Au et al Leukemia. 2021 Apr;35(4):1012-1022. doi:

    Insert

    KAT7 (KAT7 Human)
    

    Use

    Lentiviral

    Expression

    Mammalian

    Mutation

    CRISPR sites mutated (gRNA ID. 5 and A10)

    Promoter

    human EF1a promoter

    Available Since

    Dec. 3, 2020

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

33. pAGT9569

    Plasmid

    #219431

    Purpose

    Transcriptional unit (MoClo-position 2): pAtRPS5a_PapE-4LF2-N-SpCas9i-N_tNOS

    Depositor

    Tom Schreiber

    Article

    Schreiber et al Mol Plant. 2024 Mar 22:S1674-2052(24)000

    Insert

    LB_AtRPS5a:PapE-4xLF2-NLS-SpCas9i-NLS:tNOS_RB (Position 2)
    

    Use

    CRISPR and Synthetic Biology; Moclo compatible le…

    Tags

    PapE-4LF2

    Expression

    Plant

    Available Since

    July 3, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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34. pKLV2-U6gRNA5(gKAT7-5)-PGKpuro2ABFP-W

    Plasmid

    #159287

    Purpose

    Lentiviral vector expressing gRNA targeting KAT7 (gRNA ID. 5)

    Depositor

    Kosuke Yusa

    Article

    Au et al Leukemia. 2021 Apr;35(4):1012-1022. doi:

    Insert

    guide RNA targeting KAT7 (ID. 5) (KAT7 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    human U6 promoter

    Available Since

    Sept. 23, 2020

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

35. hKCNQ5(WT).ires.GFP-pcDNA3

    Plasmid

    #204360

    Purpose

    Heterologous expression in mammalian cell lines or Xenopus oocyte (T7 RNA pol)

    Depositor

    Aguan Wei

    Article

    Wei et al J Neurophysiol. 2022 Jul 1;128(1):40-61.

    Insert

    KCNQ5 (KCNQ5 Human)
    

    Expression

    Mammalian

    Promoter

    CMV/T7 RNApol

    Available Since

    Aug. 21, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

36. hKCNQ3(WT).ires.mCherry-pcDNA3

    Plasmid

    #204362

    Purpose

    Heterologous expression in mammalian cell lines or Xenopus oocyte (T7 RNA pol)

    Depositor

    Aguan Wei

    Article

    Wei et al J Neurophysiol. 2022 Jul 1;128(1):40-61.

    Insert

    KCNQ3 (KCNQ3 Human)
    

    Expression

    Mammalian

    Promoter

    CMV/T7 RNApol

    Available Since

    Aug. 21, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

37. pAGT9054

    Plasmid

    #219430

    Purpose

    Transcriptional unit (MoClo-position 2): 2x35Ss_Omega enhancer_PapE-4LF2-N-SpCas9i-N_tOCS

    Depositor

    Tom Schreiber

    Article

    Schreiber et al Mol Plant. 2024 Mar 22:S1674-2052(24)000

    Insert

    LB_2x35Ss-omega enhancer:PapE-4xLF2-NLS-SpCas9i-NLS:tOCS_RB (Position 2)
    

    Use

    CRISPR; Moclo compatible level 1 module (position…

    Tags

    PapE-4LF2

    Expression

    Plant

    Available Since

    July 31, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

38. hBACE1(D289N).ires.mCherry-pcDNA3

    Plasmid

    #204363

    Purpose

    Heterologous expression in mammalian cell lines or Xenopus oocyte (T7 RNA pol)

    Depositor

    Aguan Wei

    Article

    Wei et al J Neurophysiol. 2022 Jul 1;128(1):40-61.

    Insert

    BACE1 (BACE1 Human)
    

    Expression

    Mammalian

    Mutation

    D289N

    Promoter

    CMV/T7 RNApol

    Available Since

    Aug. 21, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

39. hKCNQ5(WT).ires.mScarlet-pcDNA3

    Plasmid

    #204361

    Purpose

    Heterologous expression in mammalian cell lines or Xenopus oocyte (T7 RNA pol)

    Depositor

    Aguan Wei

    Article

    Wei et al J Neurophysiol. 2022 Jul 1;128(1):40-61.

    Insert

    KCNQ5 (KCNQ5 Human)
    

    Expression

    Mammalian

    Promoter

    CMV/T7 RNApol

    Available Since

    Aug. 21, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

40. Cherry-HA-KCC2

    Plasmid

    #104077

    Purpose

    To visualize the expression and localization of potassium-chloride cotransporter type 2 (KCC2)

    Depositor

    Igor Medyna

    Article

    Kahle et al EMBO Rep. 2014 Jul;15(7):766-74. doi: 10

    Insert

    KCC2 (b isoform) (Slc12a5 Rat)
    

    Tags

    mCherry-HA tag

    Expression

    Mammalian

    Mutation

    EcoR1 site in rat KCC2 was removed by silent muta…

    Promoter

    UbC

    Available Since

    Feb. 20, 2018

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge