We narrowed to 6,994 results for: Cad

1. 1014 pcDNA3 T7 Akt1 K179M T308A S473A

   Plasmid

   #9031

   Depositor

   William Sellers

   Article

   Ramaswamy et al Proc Natl Acad Sci U S A. 1999 Mar 2. 96

   Insert

   Akt1 K179M T308A S473A (AKT1 Human)
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   K179M T308A S473A

   Promoter

   Available since

   Dec. 7, 2005

   Availability

   Academic Institutions and Nonprofits only

   

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2. pcDNA3-myc-his-BACH1 K52R

   Plasmid

   #17643

   Depositor

   Ronny Drapkin

   Article

   Cantor et al Proc Natl Acad Sci U S A. 2004 Feb 24. 1

   Insert

   BACH1 (BRIP1 Human)
   

   Use

   Tags

   His and Myc

   Expression

   Mammalian

   Mutation

   The lysine residue at position 52 was changed to …

   Promoter

   Available since

   April 4, 2008

   Availability

   Academic Institutions and Nonprofits only

3. AAV-nEF-dCas9

   Plasmid

   #106430

   Purpose

   Expresses SpdCas9 from the nEF promoter in AAV backbone

   Depositor

   Juan Belmonte

   Article

   Liao et al Cell. 2017 Dec 14;171(7):1495-1507.e15.

   Insert

   nEF-dCas9
   

   Use

   AAV and CRISPR

   Tags

   HA-NLS and NLS

   Expression

   Mammalian

   Mutation

   Promoter

   nEF

   Available since

   Feb. 15, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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4. pAAV-CAG-FLEX-ArgiNLS-AausFP1

   Plasmid

   #220602

   Purpose

   Cre-dependent expression of a single-cell discriminating version of AausFP1 fluorescent protein.

   Depositor

   Sam Golden

   Article

   Szelenyi et al Proc Natl Acad Sci U S A. 2024 Aug 6;121

   Insert

   AausFP1
   

   Use

   AAV and Cre/Lox

   Tags

   ArgiNLS

   Expression

   Mammalian

   Mutation

   Promoter

   CAG

   Available since

   July 31, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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5. pLKO-puro-tetON-shOGDH 2497

   Plasmid

   #110942

   Purpose

   Tet-inducible shRNA targeting OGDH

   Depositor

   William Hahn

   Article

   Ilic et al Proc Natl Acad Sci U S A. 2017 Apr 25;11

   Insert

   shOGDH (OGDH Human)
   

   Use

   Lentiviral

   Tags

   Expression

   Mutation

   Promoter

   H1/TO

   Available since

   Oct. 31, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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6. pCALNL-Rheb(S16H)

   Plasmid

   #194204

   Purpose

   Cre/LoxP-dependent expression of a constitutively active form of Rheb (S16H). Expression of Cre excises a STOP codon before Rheb(S16H), facilitating expression of a constitutively active form of Rheb.

   Depositor

   Angelique Bordey

   Article

   Lin et al Proc Natl Acad Sci U S A. 2016 Oct 4;113

   Insert

   Ras Homolog Enriched Protein in Brain (S16H) (RHEB Human)
   

   Use

   Cre/Lox

   Tags

   Expression

   Mammalian

   Mutation

   S16H

   Promoter

   Available since

   Jan. 25, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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7. pCR-Flag-IKKbeta

   Plasmid

   #15465

   Depositor

   Hiroyasu Nakano

   Article

   Nakano et al Proc Natl Acad Sci U S A. 1998 Mar 31. 9

   Insert

   IkB kinase beta (Ikbkb Mouse)
   

   Use

   Tags

   Flag

   Expression

   Mammalian

   Mutation

   Promoter

   Available since

   Oct. 10, 2007

   Availability

   Academic Institutions and Nonprofits only

8. pCAGGS-hPhyB-mCherry-HRasCT

   Plasmid

   #100281

   Purpose

   Expresses Phytochrome B (1-908 aa) fused with mCherry and Hras C-terminus in mammalian cells

   Depositor

   Kazuhiro Aoki

   Article

   Uda et al Proc Natl Acad Sci U S A. 2017 Oct 24. p

   Insert

   Phytochrome B (PHYB Mustard Weed)
   

   Use

   Tags

   mCherry fused with HRas C-terminus for plasma mem…

   Expression

   Mammalian

   Mutation

   Human codon optimized PhyB (1-908 aa)

   Promoter

   CAG promoter

   Available since

   Oct. 25, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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9. pLKO-puro-tetON-shOGDH 1714

   Plasmid

   #110941

   Purpose

   Tet-inducible shRNA targeting OGDH

   Depositor

   William Hahn

   Article

   Ilic et al Proc Natl Acad Sci U S A. 2017 Apr 25;11

   Insert

   shOGDH (OGDH Human)
   

   Use

   RNAi

   Tags

   Expression

   Mutation

   Promoter

   H1/TO

   Available since

   Nov. 2, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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10. pCDNA5/tom20-pbira(79-c)-ha

    Plasmid

    #154456

    Purpose

    expresses tom20-pbira(79-c)-ha/biochemical assay

    Depositor

    Hyun-Woo Rhee

    Article

    Kwak et al Proc Natl Acad Sci U S A. 2020 May 15. p

    Insert

    tom20-pbira(79-c)-ha (TOMM20 Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    CMV-F

    Available since

    Aug. 24, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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11. 902 pLNCX myr HA Akt1 K179M

    Plasmid

    #9006

    Depositor

    William Sellers

    Article

    Ramaswamy et al Proc Natl Acad Sci U S A. 1999 Mar 2. 96

    Insert

    Akt1 K179M (AKT1 Human)
    

    Use

    Retroviral

    Tags

    HA and myr

    Expression

    Mammalian

    Mutation

    K179M. kinase dead.

    Promoter

    Available since

    Feb. 13, 2006

    Availability

    Academic Institutions and Nonprofits only

    

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12. pLKO-puro-tetON-shOGDH 2956

    Plasmid

    #110943

    Purpose

    Tet-inducible shRNA targeting OGDH

    Depositor

    William Hahn

    Article

    Ilic et al Proc Natl Acad Sci U S A. 2017 Apr 25;11

    Insert

    shOGDH (OGDH Human)
    

    Use

    Lentiviral and RNAi

    Tags

    Expression

    Mutation

    Promoter

    H1/TO

    Available since

    Oct. 31, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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13. pRRLNeo-pEF1a-p53ash-mCerulean

    Plasmid

    #69579

    Purpose

    Expresses p53 tagged with mCerulean

    Depositor

    Galit Lahav

    Article

    Gaglia et al Proc Natl Acad Sci U S A. 2013 Sep 17;11

    Insert

    p53 (TP53 Human)
    

    Use

    Lentiviral

    Tags

    mCerulean

    Expression

    Mammalian

    Mutation

    7 silent mutations in p53 DNA to prevent targetin…

    Promoter

    EF1alpha

    Available since

    Oct. 20, 2017

    Availability

    Academic Institutions and Nonprofits only

    

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14. hHS1-M7A,H102A

    Plasmid

    #159171

    Purpose

    Human codon-optimized cytosolic labile heme reporter

    Depositor

    Amit Reddi

    Article

    Hanna et al Proc Natl Acad Sci U S A. 2016 Jul 5;113

    Insert

    hHS1-M7A,H102A
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Mutated both Met 7 and His 102 of the cyt b562 mo…

    Promoter

    CMV

    Available since

    Sept. 29, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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15. pCDNA5/mCherry_pBirA-HA_FKBP8

    Plasmid

    #154457

    Purpose

    expresses mCherry_pBirA-HA_FKBP8/biochemical assay

    Depositor

    Hyun-Woo Rhee

    Article

    Kwak et al Proc Natl Acad Sci U S A. 2020 May 15. p

    Insert

    mCherry_pBirA-HA_FKBP8 (FKBP8 Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    CMV-F

    Available since

    Aug. 24, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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16. AAV-Best1-sCD200

    Plasmid

    #164424

    Purpose

    AAV plasmid expressing soluble CD200 in retinal pigment epithelium

    Depositor

    Connie Cepko

    Article

    Wang et al Proc Natl Acad Sci U S A. 2019 May 14;11

    Insert

    CD200 (Cd200 Mouse)
    

    Use

    AAV

    Tags

    Expression

    Mammalian

    Mutation

    deleted terminal 40 amino acids

    Promoter

    Best1

    Available since

    Feb. 24, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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17. proISG15 (2-165)

    Plasmid

    #110762

    Purpose

    Bacterial expression of proISG15

    Depositor

    David Komander

    Article

    Swatek et al Proc Natl Acad Sci U S A. 2018 Mar 6;115

    Insert

    ISG15 (ISG15 Human)
    

    Use

    Tags

    N-His6-3C

    Expression

    Bacterial

    Mutation

    Promoter

    T7

    Available since

    June 13, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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18. pLenti-TRE-FH-TET3 short

    Plasmid

    #166916

    Purpose

    Lentivirus for inducible overexpression of human TET3 short isoform lacking CXXC domain (NM_001366022.1)

    Depositor

    Roland Friedel

    Article

    Halawani et al Nat Commun. 2023 Aug 24;14(1):5165. doi:

    Insert

    TET3 short isoform
    

    Use

    Lentiviral

    Tags

    HA Tag

    Expression

    Mammalian

    Mutation

    Changed nucleotide 18 (G) to (A) to delete FseI r…

    Promoter

    Available since

    March 14, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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19. pSG5-hEKLF

    Plasmid

    #67835

    Purpose

    Expression of human EKLF driven by SV40 promoter for use in activation studies

    Depositor

    James Bieker

    Article

    Mas et al Proc Natl Acad Sci U S A. 2011 Jun 28;10

    Insert

    EKLF (KLF1 Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    SV40

    Available since

    Aug. 25, 2015

    Availability

    Academic Institutions and Nonprofits only

20. pAAV-FLEX-hGTB

    Plasmid

    #26196

    Depositor

    Edward Callaway

    Article

    Wall et al Proc Natl Acad Sci U S A. 2010 Dec 14;10

    Insert

    Tet transactivator, enhanced green fluorescent protein, TVA, rabies B19 glycoprotein
    

    Use

    AAV and Cre/Lox; Adeno-associated virus

    Tags

    Expression

    Mutation

    F2A has 2A cleavage site deleted, producing htTA-…

    Promoter

    Available since

    Nov. 29, 2010

    Availability

    Academic Institutions and Nonprofits only

    

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21. pcDNA3-eGFP-NLS-RNF168

    Plasmid

    #133977

    Purpose

    mammalian expression vector of eGFP tagged wild type RNF168

    Depositor

    Daniel Durocher

    Article

    Stewart et al Cell. 2009 Feb 6;136(3):420-34. doi: 10.

    Insert

    RNF168 (RNF168 Human)
    

    Use

    Tags

    eGFP

    Expression

    Mammalian

    Mutation

    siRNA resistant sequence: GAGGAGTCGTGTTTATTGA

    Promoter

    CMV

    Available since

    Nov. 4, 2019

    Availability

    Industry, Academic Institutions, and Nonprofits

    

    Enlarge

22. pCMV5 HA-TBRII (delta Cyt)

    Plasmid

    #14051

    Depositor

    Joan Massague

    Article

    Siegel et al Proc Natl Acad Sci U S A. 2003 Jul 8. 10

    Insert

    TGF beta rec II (delta cyt) (TGFBR2 Human)
    

    Use

    Tags

    HA (PYDVPDYA)

    Expression

    Mammalian

    Mutation

    Dominant negative mutant. A stop codon was introd…

    Promoter

    Available since

    May 10, 2007

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

23. pENTR-3xFLAG-YAP1-S127A

    Plasmid

    #42239

    Depositor

    William Pu

    Article

    von Gise et al Proc Natl Acad Sci U S A. 2012 Feb 14;10

    Insert

    YAP1 (YAP1 Human)
    

    Use

    Gateway

    Tags

    3xFLAG

    Expression

    Mutation

    Serine 127 changed to alanine

    Promoter

    none

    Available since

    May 7, 2013

    Availability

    Academic Institutions and Nonprofits only

    

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24. pmCherry-EXO1a

    Plasmid

    #111629

    Purpose

    Expresses human WT Exonuclease 1a (EXO1a) tagged with mCherry in mammalian cells

    Depositor

    Marco Muzi-Falconi

    Article

    Sertic et al Proc Natl Acad Sci U S A. 2011 Aug 16;10

    Insert

    Exonuclease 1a (EXO1 Human)
    

    Use

    Tags

    mCherry

    Expression

    Mammalian

    Mutation

    Promoter

    CMV

    Available since

    June 22, 2018

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

25. AAV-short_BrokenHeart (no BC)

    Plasmid

    #86950

    Purpose

    AAV transfer plasmid containing the BrokenHeart construct: a hyperpiggybac donor transposon interrupting the tdTomato fluorophore. Transposase activity rescues coding sequence.

    Depositor

    Rob Mitra, Joseph Dougherty

    Article

    Cammack et al Proc Natl Acad Sci U S A. 2020 May 5;117

    Insert

    Brokenheart construct
    

    Use

    AAV

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    April 13, 2020

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

26. G-GECO1-Orai1

    Plasmid

    #73561

    Purpose

    Green fluorescent reporter of Orai1-associated calcium influx

    Depositor

    Michael Cahalan

    Article

    Dynes et al Proc Natl Acad Sci U S A. 2016 Jan 12;11

    Insert

    NM_032790.3 (ORAI1 Human, Synthetic)
    

    Use

    Tags

    G-GECO1

    Expression

    Mammalian

    Mutation

    Promoter

    CMV Immediate Early

    Available since

    March 10, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

27. pCR-HA-IKKbeta

    Plasmid

    #15470

    Depositor

    Hiroyasu Nakano

    Article

    Nakano et al Proc Natl Acad Sci U S A. 1998 Mar 31. 9

    Insert

    IkB kinase beta (Ikbkb Mouse)
    

    Use

    Tags

    HA

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    Oct. 10, 2007

    Availability

    Academic Institutions and Nonprofits only

28. pAPM-miR30-LRPPRC-ts1

    Plasmid

    #174268

    Purpose

    LRPPRC knockdown

    Depositor

    Jeremy Luban

    Article

    Guney et al Proc Natl Acad Sci U S A. 2024 Jul 16;12

    Insert

    LRPPRC shRNA (LRPPRC Human)
    

    Use

    Lentiviral and RNAi

    Tags

    Expression

    Mutation

    Promoter

    SFFV

    Available since

    Aug. 27, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

29. pAPM-miR30-LRPPRC-ts2

    Plasmid

    #174269

    Purpose

    LRPPRC knockdown

    Depositor

    Jeremy Luban

    Article

    Guney et al Proc Natl Acad Sci U S A. 2024 Jul 16;12

    Insert

    LRPPRC shRNA (LRPPRC Human)
    

    Use

    Lentiviral and RNAi

    Tags

    Expression

    Mutation

    Promoter

    SFFV

    Available since

    Aug. 27, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

30. Chr1q_Cassette-Integration_gRNA

    Plasmid

    #195126

    Purpose

    gRNA in a third generation Cas9 vector with GFP, targeting location downstream of Chr1q_centromere-targeting_gRNA for positive-negative selection cassette integration

    Depositor

    Jason Sheltzer

    Article

    Girish et al Science. 2023 Jul 6:eadg4521. doi: 10.11

    Insert

    Chr1q gRNA
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    Feb. 3, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge