165,613 results

1. pHBS1502 [IBB-GFP-mCherry3E]-[BFP-TDP43 deltaCTD]

   Plasmid

   #133326

   Purpose

   To test the effect of sequence on TDP43 splicing activity

   Depositor

   Rajat Rohatgi

   Article

   Schmidt et al Nat Commun. 2019 Oct 25;10(1):4890. doi:

   Insert

   TARDBP mutant (TARDBP Human)
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   Deletion of NTD in full-length TDP43

   Promoter

   Available since

   Nov. 6, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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2. pCasY1

   Plasmid

   #87687

   Purpose

   p15A plasmid expressing CasY1

   Depositor

   Jennifer Doudna

   Article

   Burstein et al Nature. 2016 Dec 22. doi: 10.1038/nature

   Insert

   CasY1
   

   Use

   Tags

   Expression

   Bacterial

   Mutation

   Promoter

   Available since

   April 27, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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3. pCMV-GFP-TFE3pA

   Plasmid

   #120201

   Purpose

   Human TFE3 poly(A) site reporter

   Depositor

   David Bartel

   Article

   Wu et al Cell. 2017 May 18;169(5):905-917.e11. do

   Insert

   TFE3 poly(A) site
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Available since

   March 4, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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4. PTK2 gRNA (BRDN0001146703)

   Plasmid

   #75544

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human PTK2

   Depositor

   David Root, John Doench

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   PTK2 (PTK2 Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   hU6

   Available since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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5. pKDsgRNA-pgaC

   Plasmid

   #154919

   Purpose

   aTc inducible gRNA targeting pgaC along with arabinose-inducible lambda red enzymes

   Depositor

   Michael Lynch

   Article

   Moreb et al CRISPR J. 2020 Dec;3(6):550-561. doi: 10

   Insert

   gRNA targeting pgaC
   

   Use

   CRISPR and Synthetic Biology

   Tags

   Expression

   Bacterial

   Mutation

   Promoter

   pTet

   Available since

   Jan. 20, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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6. pET15b-His-IkappaBalpha(FL)

   Plasmid

   #44738

   Depositor

   Gourisankar Ghosh

   Insert

   IkappaBalpga (Nfkbia Mouse)
   

   Use

   Tags

   6xHis

   Expression

   Bacterial

   Mutation

   Promoter

   Available since

   June 3, 2013

   Availability

   Academic Institutions and Nonprofits only

7. PTK2 gRNA (BRDN0001148426)

   Plasmid

   #75545

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human PTK2

   Depositor

   David Root, John Doench

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   PTK2 (PTK2 Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   hU6

   Available since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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8. PX383 Lactobacillus johnsonii Cas9

   Plasmid

   #68320

   Purpose

   Lactobacillus johnsonii Cas9

   Depositor

   Feng Zhang

   Insert

   LjCas9
   

   Use

   CRISPR

   Tags

   HA and NLS

   Expression

   Mammalian

   Mutation

   Promoter

   CMV

   Available since

   Sept. 28, 2015

   Availability

   Academic Institutions and Nonprofits only

   

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9. PTK2 gRNA (BRDN0001145734)

   Plasmid

   #75543

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human PTK2

   Depositor

   David Root, John Doench

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   PTK2 (PTK2 Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   hU6

   Available since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

10. PX386 Lactobacillus farciminis Cas9

    Plasmid

    #68323

    Purpose

    Lactobacillus farciminis Cas9

    Depositor

    Feng Zhang

    Insert

    LfCas9
    

    Use

    CRISPR

    Tags

    HA and NLS

    Expression

    Mammalian

    Mutation

    Promoter

    CMV

    Available since

    Aug. 26, 2015

    Availability

    Academic Institutions and Nonprofits only

    

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11. pCMV-MMLVgag-D3A-3L-dCas9-KOX1

    Plasmid

    #240532

    Purpose

    Expresses MMLVgag–DNMT3A-3L-dCas9-KOX1 for producing RENDER-DNMT3A-3L-dCas9-KOX1

    Depositor

    James Nuñez

    Article

    Xu et al Nat Commun. 2025 Aug 26;16(1):7948. doi:

    Insert

    MMLVgag-D3A-3L-dCas9-KOX1
    

    Use

    Tags

    FLAG, HA

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    Aug. 19, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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12. pHIV-LacZ-SapI

    Plasmid

    #237610

    Purpose

    Destination vector for complete TCR library

    Depositor

    Michael Birnbaum

    Article

    Gaglione et al bioRxiv 2025.04.24.649726

    Type

    Empty backbone

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    Available since

    Aug. 8, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

13. GST-GRP78-Full Length (pGEX4T1)

    Plasmid

    #238421

    Purpose

    Expresses GRP78 Full Length fused to the GST Tag

    Depositor

    Amy Shiu Lee

    Article

    Tseng et al Neoplasia. 2019 Aug;21(8):837-848. doi:

    Insert

    78-kDa glucose-regulated protein (HSPA5 Human)
    

    Use

    Tags

    GST

    Expression

    Bacterial

    Mutation

    Promoter

    Available since

    Aug. 7, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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14. UAS:dL5-mCer3

    Plasmid

    #241797

    Purpose

    Expresses cytoplasmic fluorogen activating protein dL5** fused to mCer under UAS promoter

    Depositor

    Harold Burgess

    Article

    Sharma et al bioRxiv [Preprint]. 2025 Apr 5:2025.04.0

    Insert

    dL5-mCer
    

    Use

    Zebrafish transgenesis (tol1)

    Tags

    Expression

    Mutation

    Promoter

    Available since

    July 24, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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15. 73-79 ZBneg PANCS-binder negAP

    Plasmid

    #240121

    Purpose

    ZBneg PANCS-binder negative AP

    Depositor

    Bryan Dickinson

    Article

    Styles et al bioRxiv [Preprint]. 2025 Jan 17:2025.01.

    Insert

    -ZBneg-RNAPC fusion
    

    Use

    Tags

    Expression

    Mutation

    Promoter

    Custom

    Available since

    July 22, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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16. 73-21 KRAS PANCS-binder posAP

    Plasmid

    #240119

    Purpose

    KRAS G12D PANCS-binder positive AP

    Depositor

    Bryan Dickinson

    Article

    Styles et al bioRxiv [Preprint]. 2025 Jan 17:2025.01.

    Insert

    KRas-RNAPC Pos AP fusion
    

    Use

    Tags

    Expression

    Bacterial

    Mutation

    Promoter

    custom

    Available since

    July 10, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. ATP5F1B-turboGFP

    Plasmid

    #239795

    Purpose

    Expresses human ATP5F1B tagged with turboGFP

    Depositor

    Samantha Lewis

    Article

    Rose et al bioRxiv [Preprint]. 2025 Mar 25:2025.03.

    Insert

    ATP5F1b (ATP5F1B Human)
    

    Use

    Tags

    turboGFP

    Expression

    Mammalian

    Mutation

    Promoter

    CMV

    Available since

    June 12, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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18. pYPQAT01

    Plasmid

    #223373

    Purpose

    T-DNA vector for SpCas9 mediated mutagenesis for dicot plants; NGG PAM; Cas9 was driven by AtUBQ10 and the sgRNA was driven by AtU3 promoter; Hygromycin for plants selection.

    Depositor

    Yiping Qi

    Article

    Cheng et al Plant Cell. 2025 Apr 9:koaf081. doi: 10.

    Insert

    AtUBQ10-SpCas9-AtU3-gRNA scaffold
    

    Use

    CRISPR

    Tags

    3x FLAG and NLS

    Expression

    Plant

    Mutation

    Promoter

    Available since

    April 10, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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19. pMT-Ex

    Plasmid

    #231106

    Purpose

    Inducible protein expression in insect cell culture. Stable cell line generation.

    Depositor

    Michael Jeltsch

    Type

    Empty backbone

    Use

    Tags

    6xHis and V5

    Expression

    Insect

    Mutation

    Promoter

    Drosophila metallothionein promoter, MT

    Available since

    April 1, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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20. pLenti-CRISPRv2-sgIl1r1_#2-hygro

    Plasmid

    #231990

    Purpose

    Knockout mouse Il1r1

    Depositor

    Brian Ruffell

    Article

    Hanggi et al Cancer Cell. 2024 Nov 13:S1535-6108(24)0

    Insert

    sgRNA with Cas9 and hygromycin resistance (Il1r1 Mouse)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    Available since

    Feb. 19, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge